Literature Review : Pengaruh Batuk Efektif Untuk Pengeluaran Sputum Pada Pasien Tuberculosis

Tuberculosis (TB) is in infectious disease that attacks the lungs caused by the bacterium Mycobacterium tuberculosis. Tuberculosis patients usually have symptoms of a prolonged cough, from the cought it can cause shortness of breath in someone who experiences these symtoms because there are too many secretions that are difficult to expel, causing a forced expiration. Forced expiration is one of the non-pharmacological interventions carried out to expel secretions, increase lung expansion, mobilize secretions and prevent side effects of retention of secretions. The purpose of this study was to describe the effect of forced expiration for sputum extraction in tuberculosis patients. Used in this study was a literature review from a database that had been determined used the keywoard tuberculosis, forced expiration, and sputum extraction. Obtained after forced expiration was reduced in the number of secretions in the patient. This study is that forced expiration can effectively reduce the amount of secretions in the body of tuberculosis patients. Keywoard: Forced expiration; Sputum extraction; Tuberculosis (Pulponary tuberculosis) AbstrakTuberculosis (TB) adalah salah satu penyakit infeksi yang menyerang bagian paru-paru disebabkan oleh bakteri mycrobacterium tuberculosis. Pendertia tuberculosis biasanya memiliki gejala batuk yang berkepanjangan, dari batuk tersebut dapat menyebabkan sesak nafas pada seseorang yang mengalami gejala tersebut karena terlalu banyak sekret yang susah untuk dikeluarkan sehingga menyebabkan batuk efektif. Batuk efektif adalah salah satu tindakan non farmakologi yang dilakukan untuk pengeluaran sekresi, meningkatkan ekspansi paru, memobilisasi sekret dan mencegah efek samping dari retensi sekresi. Dari karya tulis ilmiah adalah untuk mengetahui gambaran tentang pengaruh batuk efektif untuk pengeluaran sputum pada pasien tuberculosis. Metode yang dilakukan dalam penelitian adalah literature review dari database yang telah ditentukan dengan menggunakan kata kunci Tuberculosis, latihan batuk efektif, dan pengeluaran sputum. Hasil yang didapatkan setelah dilakukan tindakan latihan batuk efektif yaitu banyaknya sekret pada pasien mulai berkurang. Kesimpulan karya tulis ilmiah ini bahwa tindakan latihan batuk efektif dapat mengurangi jumlah sekresi yang ada pada tubuh pasien tuberculosis.Kata kunci: Latihan batuk efektik; Pengeluaran Sputum; Tuberculosis ( TB Paru)

Neck Stabilization Exercises Enhance Respiratory Function after Stroke: Respiratory Function Index Change Trajectory Analyzed Using a Hierarchical Linear Model

Background and Objectives: This study aimed to assess the effect of neck stabilization exercise on respiratory function in stroke patients through longitudinal observation and determine whether there is a difference in its effect based on the side of paralysis in the patients. It is difficult to observe the amount of change observed in individuals and groups as most intergroup comparison studies only use mean values. To address these shortcomings, this study adopted a hierarchical linear model (HLM) in our trajectory analysis. Materials and Methods: We conducted neck stabilization training three times a week for four weeks in a single group of 21 stroke patients. To evaluate respiratory function, their forced vital capacity (FVC), forced expiratory volume in the first second (FEV1), forced expiration ratio (FEV1/FVC), and peak cough flow (PCF) were measured. Data analysis was performed using HLM 8.0. Results: A significant increase was found in the respiratory function after neck stabilization training (p < 0.05). While neck stabilization training overall was longitudinally effective, the growth rate of respiratory function in left-sided paralytic patients was less than the whole group value. Conversely, the growth rate of respiratory function in right-sided paralytic patients was greater than the whole group value. Conclusions: This study demonstrated that neck stabilization training is longitudinally effective in improving respiratory function in stroke patients. Additionally, the growth rate of respiratory function was greater in patients with right side paralysis than in patients with left side paralysis.

Kumis treatment in medical rehabilitation of patients with pneumonia associated with the novel coronavirus infection COVID-19

The results of evaluating the effectiveness of the use of kumis treatment in 64 patients who have had pneumonia associated with the novel coronavirus infection COVID-19 are presented. It was found that the use of kumis treatment in addition to the basic complex in 32 patients of the main group has led to an increase in exercise tolerance by 13.6 % (p < 0,05), a decrease in the severity of shortness of breath by 36.3 % (p < 0.05), and contributed to the improvement of the parameters of the function of external respiration with an increase in the vital capacity of the lungs by 14,4 % (p < 0,05), the volume of forced expiration — by 24,5 % (p < 0,05). Against the background of kumis treatment, the patients of the main group showed a significant decrease in the severity of depression and anxiety — by 62.5 % (p < 0.05) and by 62.3 % (p < 0,05), respectively, an improvement in the parameters of «well-being» by 62,2 % (p < 0.05), «activity» — by 37,6 % (p < 0,05), «mood» — by 35,5 % (p < 0,05), compared to the initial values. The dynamics of parameters in the patients of the control group against the background of the basic complex turned out to be less significant in comparison with the main group.

The relatıonship between shooting performance and respiratory muscle strength in archers aged 9-12

Introduction: The aim of this study is to investigate the relationship between shooting performance and pulmonary functions and respiratory muscle strength in archers. Material and methods: The research was conducted with 31 boy and 11 girl archers aged 9-12. The forced vital capacity (FVC), forced expiration volume in one second (FEV1), FEV1/FVC, peak expiratory flow (PEF), maximum voluntary ventilation (MVV), maximum inspiratory pressure (MIP), and maximum expiratory pressure (MEP) of the archers were measured. To determine the shooting performance, a total of 30 shots (15+15) were taken from an 18-meter distance in closed shooting range. Results: A significant difference was found between the 15 shots done in each half and the total shot point and the averages of FVC (r=0.375, 0.353, 0.378 respectively) and FEV1 (r=0.368, 0.339, 0.367 respectively). However, a significant difference was not found among these shot points and other respiratory parameters (p>0.05). A relationship was detected between the second 15-shot points of boy archers and MEP (r=0.370). Conclusions: A strong correlation was not found between the respiratory parameters and shooting performances of the archers in this study. However, it is thought that this level of relationship will rise as training level and age increases.

The Effect of Participation in Educational Games Activity on Respiratory Values and Anthropometric Properties in Children

Aim: In this study, it was aimed to examine the anthropometric properties and respiratory parameter values of students between the ages of 10-11 who regularly participate in educational games. Methods: 34 students studying, İncesu Kızılören Parlaklar Secondary School, voluntarily participated in the study. While the experimental group (n=18) participated in educational game activities three days a week along with physical education lessons for five weeks, the control group (n=16) attended only physical education lessons. They did not participate in the educational game activities. Two measurements were carried out to the students as pre-test and post-test. Results: While the anthropometric measurements of the students participating in the study were measured with the Tanita measuring device, their respiration values were determined with a spirometer. Data are shown as arithmetic mean and standard deviation. A dependent sample t-test was used to compare independent groups and also paired sample t-test was used to compare dependent groups. The significance level was determined as (p<0.05). In the study, it was seen that there was a significant difference in body fat mass, lean body mass (FFM), total body fluid (ibw) values of the experimental group (p<0.05), while only a significant difference was found in basal metabolic rate (bmh) values in the control group. In the respiratory function values, the forced vital capacity (fvc), the air volume removed in the first second of forced expiration (fev1) of the experimental group. While the difference in peak expiratory flow (pef) and maximum voluntary ventilation (mvv) values were found to be significant, fev1, pef, and mvv values were found to be significant in the control group (p<0.05). Conclusion: It was seen that educational games had a positive effect on anthropometric measurement and respiration values in primary school students aged 10-11 years. We think that increasing the time of the physical education lessons and sparing more time to educational games, explaining the importance of educational games to physical education teachers, school administration, and students, and regular educational game competitions will make a significant contribution to the development of children. Keywords: Educational Games, Anthropometric Measurement, Respiratory

Effect of Methylation Status of lncRNA-MALAT1 and MicroRNA-146a on Pulmonary Function and Expression Level of COX2 in Patients With Chronic Obstructive Pulmonary Disease

This study aimed to investigate the role of methylation of MALAT1 and miR-146a in the pathogenesis of chronic obstructive pulmonary disease (COPD). COPD patients were grouped according to their methylation status of MALAT1 and miR-146a promoters, and we found that forced vital capacity, volume that has been exhaled at the end of the first second of forced expiration, and diffusion capacity for carbon monoxide were the highest in the MALAT1 HYPO + miR-146a HYPER group and lowest in the MALAT1 HYPER + miR-146a HYPO group, and COPD patients with hypermethylated MALAT1 showed lower expression of MALAT1 than that in the COPD patients with hypomethylated MALAT1. Meanwhile, miR-146a was the most significantly upregulated in the MALAT1 HYPER + miR-146a HYPO group and the most significantly downregulated in the MALAT1 HYPO + miR-146a HYPER group. Both prostaglandin E1 and cyclooxygenase 2 (COX2) expression were the highest in the MALAT1 HYPO + miR-146a HYPER group and the lowest in the MALAT1 HYPER + miR-146a HYPO group. In conclusion, our results established a MALAT1/miR-146a/COX2 signaling axis. The overexpression of MALAT1 could increase the expression of COX2 by inhibiting the expression of miR-146a, thus affecting the pulmonary function of COPD patients.

Middle-Ear Resonance Frequency and Eustachian Tube Function in Players of Wind Instruments

<b><i>Introduction:</i></b> The effect of the continuous forced expiration action of players of wind instruments to produce sound, on the eustachian tube functions and the middle-ear resonance frequency (RF), has not been investigated in the literature to date. The aim of this study is to evaluate eustachian tube functions and the middle-ear RF of players of wind instruments. <b><i>Methods:</i></b> In this prospective case-control clinical study, a study group of 28 players of wind instruments in the orchestra (28 participants, 56 ears) and a control group of 34 volunteers (34 participants, 68 ears) were included. The eustachian function of wind instrument players in a symphony orchestra was measured using an automatic eustachian tube function test in acoustic tympanometry and the RF of the middle ear was determined in multifrequency tympanometry. <b><i>Results:</i></b> There was a statistically significant difference among the musicians, especially in players of woodwind instruments, in terms of dysfunction of the eustachian tubes (<i>p</i> = 0.048). In the musicians, the pre- and postperformance RF mean values for all ears were 925 and 1,020 Hz, respectively, and these were significantly different (<i>p</i> = 0.004). <b><i>Conclusion:</i></b> This is the first study to uses multifrequency tympanometry to examine the middle-ear RF and eustachian tube function of wind instrument musicians in an orchestra. Eustachian tube dysfunction was found to be more prominent and a higher RF of the middle ear was seen after a performance, especially in players of wood wind instruments. However, the effect of these on the professional performance of players of wind instruments should be investigated in future work.

Predictors of exercise-induced bronchoconstriction in subjects with mild asthma

Background Physical effort is capable of triggering airway obstruction in asthmatics, the so-called exercise-induced bronchoconstriction in asthma (EIBa). This study was performed in subjects with mild persistent asthma, aiming to find predictors for developing EIBa. Methods In 20 subjects with mild asthma, measurements of baseline functional respiratory parameters and airways responsiveness by a methacholine challenge were obtained on the first day. A maximal, symptom-limited incremental cardiopulmonary exercise test (CPExT) was performed the day after, with subsequent, repeated maneuvers of maximal full forced expiration to monitor the FEV1 change at 1,3,5,7,10 and 15 min after the end of the exercise. Results 19 subjects completed the two-days protocol. No functional parameters both at rest and during effort were useful to predict EIBa after stopping exercise. In asthmatics with EIBa, mean Inspiratory Capacity (IC) did not increase with increasing ventilatory requirements during CPExT because 6 of them (50%) displayed dynamic pulmonary hyperinflation (DH), as documented by their progressive increase of end-expiratory lung volume. This subgroup, showing earlier post-exercise FEV1 fall, had significantly lower forced mean expiratory flow between 25% and 75% of forced vital capacity (FEF25-75%) at rest (p < 0.05) and higher airways responsiveness, expressed as PD20FEV1 (p < 0.05) as compared with other asthmatics with EIBa. Conclusions No functional respiratory parameters seem to predict EIBa in mild asthmatics. However, in those with EIBa, a subgroup developed DH during exercise, and this was associated with a baseline reduced forced expiratory flow rates at lower lung volumes and higher airway hyperresponsiveness, suggesting a prominent small airways impairment.

Effect of osteopathic manipulative therapy on pulmonary function testing in children with asthma

Context Asthma is a leading cause of pediatric chronic illness, and poor disease control can lead to decreased quality of life and impaired academic performance. Although osteopathic manipulative treatment (OMT) has been shown to have positive effects on pulmonary function in adult patient populations, less is known about its impact in children. Objectives To evaluate changes in pulmonary function testing (PFT) in pediatric patients on the same day they received OMT compared with PFT in those who received usual care. Methods We recruited patients between the ages of 7–18 years with a diagnosis of asthma who were receiving routine care at a primary care asthma clinic and had undergone baseline spirometry. Patients were excluded if they met any of the following criteria: clinical indication for pre- and postbronchodilator spirometry on the day of their visit, albuterol use in the last 8 hours, oral steroid use in the previous 2 weeks, or diagnosis of asthma exacerbation in the previous 4 weeks. Eligible patients were then randomized to either an OMT or a control group. Patients in the OMT group were treated with rib raising and suboccipital release in addition to standard asthma care, while control group patients received standard care only. A second PFT was performed for patients in both groups at the end of the visit. OMT was performed by multiple osteopathic pediatric residents specifically trained for this study. Change in spirometry results (forced vital capacity [FVC], forced expiration volume in 1 second [FEV1], FVC/FEV1, and forced expiratory flow 25–75%) were then compared. Results The study population included 58 patients: 31 (53.4%) were assigned to the OMT group and 27 (46.6%) were assigned to the standard of care group. Patients who received OMT had greater improvement in all spirometry values compared to the usual group; however, these changes were not statistically significant. Conclusions The benefits of OMT on short term spirometry results in pediatric asthma patients remain unclear.

Predictors of exercise-induced bronchoconstriction in subjects with mild asthma

Background Physical effort is a stimulus capable of triggering airway obstruction in asthmatics, the so-called exercise-induced bronchoconstriction in asthma (EIBa). This study was performed in subjects with mild persistent asthma, aiming to find predictors for developing EIBa. Methods In 20 subjects with mild asthma, measurements of baseline functional respiratory parameters and airways responsiveness by a methacholine challenge were obtained on the first day. The day after, a maximal, symptom-limited incremental cardiopulmonary exercise test (CPExT) was performed, with subsequent, repeated maneuvers of maximal full forced expiration to monitor the FEV 1 change at 1,3,5,7,10 and 15 minutes after the end of exercise. Results 19 subjects completed the two-days protocol. No functional parameters both at rest and during effort were useful to predict EIBa after stopping exercise. In asthmatics with EIBa, mean Inspiratory Capacity (IC) did not increase with increasing ventilatory requirements during CPExT, because 6 of them (50%) displayed dynamic pulmonary hyperinflation (DH), as documented by their progressive increase of end-expiratory lung volume. This subgroup, showing earlier post-exercise FEV 1 fall, had significantly lower forced mean expiratory flow between 25% and 75% of forced vital capacity (FEF 25-75% ) at rest (p<0.05) and higher airways responsiveness, expressed as PD 20 FEV 1 (p<0.05) as compared with other asthmatics with EIBa. Conclusions No functional respiratory parameters seem to predict EIBa in mild asthmatics. However, in those with EIBa, a subgroup developed DH during exercise, and this was associated with a baseline reduced forced expiratory flow-rates at lower lung volumes and higher airway hyperresponsiveness, suggesting a prominent small airways impairment.