scholarly journals Association between myostatin serum concentration and body fat level in peri- and postmenopausal women.

2021 ◽  
Author(s):  
Iwona Bojar ◽  
Radosław Mlak ◽  
Iwona Homa-Mlak ◽  
Monika Prendecka ◽  
Alfred Owoc ◽  
...  
Keyword(s):  
Blood Serum ◽  
Postmenopausal Women ◽  
Body Fat ◽  
Hormone Replacement ◽  
Serum Levels ◽  
The Body ◽  
Independent Predictive Factor ◽  
Average Percentage ◽  
Body Composition Change ◽  
Fat Level

IntroductionEvery year over 25 million women worldwide experience menopause symptoms. Menopause lead to the occurrence and intensification of many psychological and somatic disorders including body composition change. Myostatin may play a crucial role in the remodelling of muscle and fat tissue. The aim of the study was to determine the relationship between the level of body fat and the concentration of myostatin protein in serum of peri- or postmenopausal women.Material and methodsThe study included 300 Caucasian women (in perimenopause or postmenopause). Detail data were collected at a single time point from all enrolled women. The data included: age, body mass index, hormone replacement therapy and body fat. Measurements of adipose tissue were performed using electronic skinfold calipers. Serum levels of myostatin were determined using Human Myostatin ELISA Kit.ResultsThe average myostatin concentration in blood serum was 6.58±3.59 ng/ml. The average percentage of body fat was 32.7±6.3 (range: 16.1 to 50.7). The percentages of women in particular groups of the body fat level (I, II, III, IV and V) amounted to 1.7%, 11%, 35.3%, 30.7% and 21.3% respectively. Myostatin level in blood serum was significantly decreased (median concentrations: 5.5 vs 7.0 ng/ml, p=0.0269) in subjects with higher body fat (groups IV and V) compared to the ones classified as having normal or low level of body fat (groups I-III). Myostatin was independent predictive factor of the occurrence of high body fat (p=0.0463).ConclusionsDecreased level of myostatin is related to higher level of body fat in peri- and postmenopausal women

scholarly journals Factors Predicting the Response to a Vitamin D-Fortified Milk in Healthy Postmenopausal Women

Nutrients ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 2641 ◽  
Author(s):  
Rebeca Reyes-Garcia ◽  
Antonia Garcia-Martin ◽  
Santiago Palacios ◽  
Nancy Salas ◽  
Nicolas Mendoza ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Vitamin D ◽  
Postmenopausal Women ◽  
Body Mass ◽  
Body Fat ◽  
Dietary Intervention ◽  
The Body ◽  
Hydroxyvitamin D ◽  
Percentage Of Body Fat ◽  
Fortified Milk

Background: Milk products fortified with vitamin D may constitute an alternative to pharmacological supplements for reaching the optimal levels of serum 25-hydroxyvitamin D [25(OH)D]. Our aim was to analyze the response of serum 25(OH)D and its predictive factors in postmenopausal healthy women after a dietary intervention with a milk fortified with vitamin D and calcium. Methods: We designed a prospective study including 305 healthy postmenopausal women who consumed a fortified milk with calcium (900 mg/500 mL) and vitamin D3 (600 IU/500 mL) daily for 24 months. Results: The 25(OH)D concentrations at 24 months were correlated to weight, to body mass index, to the percentage of fat, triglycerides and to baseline 25(OH)D levels. We found significant differences in the levels of 25(OH)D at 24 months according to baseline 25(OH)D levels (p < 0.001) and body mass index (p = 0.019) expressed at quartiles. Multivariate analysis showed an association between levels of 25(OH)D after the intervention and at baseline 25(OH)D (Beta = 0.47, p < 0.001) and percentage of body fat (Beta = −0.227, p = 0.049), regardless of the body mass index. Conclusions: In healthy postmenopausal women, the improvement in 25(OH)D after an intervention with a fortified milk for 24 months depends mainly on the baseline levels of serum 25(OH)D and on the percentage of body fat.

Combined Effects of Dietary Protein Type and Fat Level on the Body Fat-Reducing Activity of Conjugated Linoleic Acid (CLA) in Rats

2005 ◽  
Vol 69 (12) ◽  
pp. 2409-2415 ◽  
Author(s):  
Asuka AKAHOSHI ◽  
Kazunori KOBA ◽  
Rie ENMOTO ◽  
Kazuko NISHIMURA ◽  
Yukiko HONDA ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Body Fat ◽  
Dietary Protein ◽  
The Body ◽  
Combined Effects ◽  
Fat Level ◽  
Reducing Activity

scholarly journals Effects of Hormone Replacement Therapy Type and Route of Administration on Plasma Matrix Metalloproteinases and Their Tissue Inhibitors in Postmenopausal Women

2006 ◽  
Vol 91 (8) ◽  
pp. 3123-3130 ◽  
Author(s):  
K. C. Lewandowski ◽  
J. Komorowski ◽  
D. P. Mikhalidis ◽  
M. Bienkiewicz ◽  
B. K. Tan ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Hormone Replacement Therapy ◽  
Matrix Metalloproteinases ◽  
Replacement Therapy ◽  
Postmenopausal Women ◽  
Hormone Replacement ◽  
Serum Levels ◽  
Tissue Inhibitors ◽  
Healthy Women ◽  
Transdermal Estradiol

Abstract Background: Matrix metalloproteinases (MMPs) are implicated in numerous disease states including cardiovascular disease and cancer. Because recent studies have shown a detrimental effect of hormone replacement therapy on cardiovascular disease and breast cancer, we investigated whether there are any differences in the concentrations of MMPs and their tissue inhibitors (TIMPs) in women receiving various forms of postmenopausal therapy. Material and Methods: A total of 195 healthy postmenopausal women were assessed: 46 were taking tibolone, 47 were taking transdermal estradiol, 46 were taking conjugated equine estrogens (CEE), and 56 were not taking any menopausal therapy (CTR). Plasma levels of MMP-2 and -9 and TIMP-1 and TIMP-2 were measured by ELISA methods. Results: MMP-9 levels were significantly higher in the CEE group in comparison with healthy women not receiving menopausal therapy (P &lt; 0.05). In contrast, MMP-9 levels in the tibolone group were significantly lower than in any other group (P &lt; 0.01, compared with transdermal estradiol and CTR, and P &lt; 0.001, compared with CEE). MMP-9 to TIMP-1 ratio was also significantly higher in the CEE, compared with CTR (P &lt; 0.05), and lower in the tibolone group (P &lt; 0.01, compared with all groups). MMP-2 levels were higher in the CEE group, compared with healthy women not receiving any menopausal therapy, and women taking tibolone (P &lt; 0.05). Conclusions: Our study demonstrates differential effects of various forms of postmenopausal therapy on serum levels of MMP-9 and MMP-2. It remains to be established whether these differences might be associated with differences in risks of cardiovascular disease and cancer in these women.

Physical activity, body fat, and serum c-reactive protein in postmenopausal women with and without hormone replacement

2003 ◽  
Vol 15 (1) ◽  
pp. 91-100 ◽  
Author(s):  
Patricia J. Manns ◽  
Daniel P. Williams ◽  
Christine M. Snow ◽  
Rosemary C. Wander
Keyword(s):  
Physical Activity ◽  
Postmenopausal Women ◽  
Body Fat ◽  
Hormone Replacement ◽  
C Reactive Protein ◽  
Reactive Protein

scholarly journals BODY FAT AND VISCERAL FAT AMONG MARRIED MAN AND WOMAN IN RURAL SOCIETIES

2021 ◽  
Vol 12 (02) ◽  
pp. 80-92
Author(s):  
Loan Subarno ◽  
Samsudin ◽  
Nur Ali
Keyword(s):  
Body Fat ◽  
Visceral Fat ◽  
Eating Behaviors ◽  
Impedance Analysis ◽  
The Body ◽  
P Value ◽  
Percentage Body Fat ◽  
Fat Level ◽  
Positive Correlations ◽  
The Village

High levels of body fat and visceral fat are the causes of metabolic disorders which are influenced by several factors, including gender. Good social economic condition has brought many changes in the food choices and eating behaviors among married man and woman in rural societies. This shift around nutrition has given rise to Body Fat dan Visceral Fat level which is lead to degenerative illness. Considering this condition, the present study was planned to 1) determine the differences of Body Fat and Visceral fat among married Man and Woman and 2) Find the relationship between the Body Fat with Visceral Fat among Man and Woman. A total of 34 Karang Tengah Villagers 15 Men, 19 women, 18-30+ years from all over the village were voluntary joining the study. Verbal Inform concern was obtained, a self-administered questionnaire was given, and the Body composition were measured by bio-electric impedance analysis device. Data were analyzed using SPSS – 23. The results indicated that Body Fat average in Man were lower than Woman with 21,28% and 39,25%, respectively (p-value 0.000). But different result showed in Visceral Fat, Men were Higher than Women, 10,4 and 7,26, respectively (p-value 0.028). Significant positive correlations were found among Body Fat and Visceral Fat level in both Men (r 0,977, p-value 0,000) and Women (r 0,971, p-value 0,000). Findings of present study suggest that there is need for coordinated efforts to reduce the prevalence of high percentage Body Fat and Visceral Fat and to develop healthy eating behaviors among Villagers.

scholarly journals Tocotrienol Supplementation Led to Higher Serum Levels of Lysophospholipids but Lower Acylcarnitines in Postmenopausal Women: A Randomized Double-Blinded Placebo-Controlled Clinical Trial

2021 ◽  
Vol 8 ◽  
Author(s):  
Chwan-Li Shen ◽  
Huanbiao Mo ◽  
Dale M. Dunn ◽  
Bruce A. Watkins
Keyword(s):  
Oxidative Stress ◽  
Postmenopausal Women ◽  
Serum Levels ◽  
Phospholipid Metabolism ◽  
The Body ◽  
Controlled Clinical Trial ◽  
Serum Samples ◽  
Major Health Problem ◽  
Double Blinded ◽  
And Oxidative Stress

Osteoporosis is a major health problem in postmenopausal women. Herein we evaluated the effects of 12-week tocotrienols (TT) supplementation on serum metabolites in postmenopausal, osteopenic women. Eighty-nine participants (59.7 ± 6.8 yr, BMI 28.7 ± 5.7 kg/m2) were assigned to 3 treatments: placebo (860 mg olive oil/day), 300mg TT (300 mg TT/day), and 600mg TT (600 mg TT/day) for 12 weeks. TT consisted of 90% δ-TT and 10% γ-TT. In this metabolomic study, we evaluated the placebo and 600mgTT at baseline and 12 weeks. As expected, TT and its metabolite levels were higher in the supplemented group after 12 weeks. At baseline, there were no differences in demographic parameters or comprehensive metabolic panels (CMP). Metabolomics analysis of serum samples revealed that 48 biochemicals were higher and 65 were lower in the 600mg TT group at 12 weeks, compared to baseline. The results confirmed higher serum levels of tocotrienols and lysophospholipids, but lower acylcarnitines and catabolites of tryptophan and steroids in subjects given 600mg TT. In summary, 12-week TT supplementation altered many serum metabolite levels in postmenopausal women. The present study supports our previous findings that TT supplementation helps reduce bone loss in postmenopausal osteopenic women by suppressing inflammation and oxidative stress. Furthermore, the body incorporates TT which restructures biomembranes and modifies phospholipid metabolism, a response potentially linked to reduced inflammation and oxidative stress.

Cocoa-rich chocolate and body composition in postmenopausal women: a randomised clinical trial

2020 ◽  
pp. 1-9 ◽  
Author(s):  
Irene A. Garcia-Yu ◽  
Luis Garcia-Ortiz ◽  
Manuel A. Gomez-Marcos ◽  
Emiliano Rodriguez-Sanchez ◽  
Cristina Lugones-Sanchez ◽  
...  
Keyword(s):  
Body Composition ◽  
Postmenopausal Women ◽  
Body Fat ◽  
Fat Mass ◽  
The Body ◽  
Control Group ◽  
Body Fat Percentage ◽  
Body Fat Mass ◽  
Fat Percentage ◽  
Habitual Diet

Abstract During menopause, women undergo a series of physiological changes that include a redistribution of fat tissue. This study was designed to investigate the effect of adding 10 g of cocoa-rich chocolate to the habitual diet of postmenopausal women daily on body composition. We conducted a 6-month, two-arm randomised, controlled trial. Postmenopausal women (57·2 (sd 3·6) years, n 132) were recruited in primary care clinics. Participants in the control group (CG) did not receive any intervention. Those of the intervention group (IG) received 10 g daily of 99 % cocoa chocolate in addition to their habitual diet for 6 months. This quantity comprises 247 kJ (59 kcal) and 65·4 mg of polyphenols. The primary outcomes were the between-group differences in body composition variables, measured by impendancemetry at the end of the study. The main effect of the intervention showed a favourable reduction in the IG with respect to the CG in body fat mass (–0·63 kg (95 % CI –1·15, –0·11), P = 0·019; Cohen’s d = –0·450) and body fat percentage (–0·79 % (95 % CI –1·31, –0·26), P = 0·004; Cohen’s d = –0·539). A non-significant decrease was also observed in BMI (–0·20 kg/m2 (95 % CI –0·44, 0·03), P = 0·092; Cohen’s d = –0·345). Both the body fat mass and the body fat percentage showed a decrease in the IG for the three body segments analysed (trunk, arms and legs). Daily addition of 10 g of cocoa-rich chocolate to the habitual diet of postmenopausal women reduces their body fat mass and body fat percentage without modifying their weight.

Seasonal Changes of Fat Content in the Yellow Perch (Perca flavescens) of Two Laurentian Lakes

1975 ◽  
Vol 32 (11) ◽  
pp. 2214-2221 ◽  
Author(s):  
George E. Newsome ◽  
Gérard Leduc
Keyword(s):  
Body Fat ◽  
Yellow Perch ◽  
Perca Flavescens ◽  
Fat Content ◽  
The Body ◽  
Differential Mortality ◽  
Fat Reserves ◽  
Body Fat Content ◽  
Fat Level ◽  
Males And Females

Different body fat reserves in male and female yellow perch (Perca flavescens) may determine a marked differential mortality during the winter. This was revealed by a study in two Laurentian lakes of the Province of Quebec harboring stunted yellow perch with a marked predominance of males. The proportion of females in each year-class is markedly smaller, thus suggesting a higher mortality among immature and mature females than among males.In an attempt to explain the differential mortality, the seasonal variation of body fat content in males and females was measured; also the fat level at time of death caused by starvation under laboratory conditions was determined. The results showed that in the females the body fat content falls to a critical level of about 2% at least 4 mo before spawning, whereas the males maintain a fat level of almost 5% throughout winter.

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