The role of Radiation Therapy in Treatment of COVID-19 induced Pneumonia

2020 ◽  
Vol 1 (1) ◽  
Author(s):  
Eter Natelauri ◽  
Tea Natelauri ◽  
Zurab Tcheishvili
Keyword(s):  
Radiation Therapy ◽  
Second Phase ◽  
Inflammatory Reactions ◽  
Infected People ◽  
Search Terms ◽  
Low Dose Radiotherapy ◽  
Early Results ◽  
Pubmed Database ◽  
Pros And Cons

Background: Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Infected people can develop severe inflammatory reactions, which can lead to pneumonia, acute respiratory distress syndrome, and death. The use of radiation in the treatment of COVID-19 induced pneumonia sounds unusual, but is currently being investigated in clinical trials. Some early results have been already published. This study aims to review existing information about the role of radiation therapy in the Treatment of COVID-19 induced pneumonia. Methods and Materials: An electronic search of the PubMed database and additional resources ware used to obtain key literature. The following search terms were used: “Radiation therapy” and “COVID-19”. Results: Search resulted in 137 citations. The first phase of screening identified 13 articles, from which nine articles were identified to be relevant for the second phase of screening. Six articles were included in the review. Conclusion: Low-dose radiotherapy has been considered as a potential treatment for COVID-19 induced pneumonia. The benefits of LDRT for pneumonia have been reported since the early 20th. However knowledge is lacking, hence further investigation of the pros and cons of this method is strongly recommended. LDRT as a prospective cure of COVID-19 induced pneumonia is worthy of research in a clinical setting.

Long Non-coding RNAs in Metabolic and Inflammatory Pathways in Obesity

2020 ◽  
Vol 26 (27) ◽  
pp. 3317-3325
Author(s):  
Yue Shi ◽  
Jiayuan Qu ◽  
Liyue Gai ◽  
Ding Yuan ◽  
Chengfu Yuan
Keyword(s):  
Metabolic Pathways ◽  
Metabolic Diseases ◽  
Metabolic Stress ◽  
Inflammatory Reactions ◽  
Metabolic Inflammation ◽  
Pubmed Database ◽  
Prevention And Treatment ◽  
New Ideas ◽  
Non Coding Rnas

Background: In recent decades, the incidence of obesity has been rising globally. Obesity can often cause various inflammatory reactions, resulting in several diseases that threaten public health. The purpose of this review is to explore the role of long non-coding RNAs in metabolic obesity and find new targets for the prevention and treatment of metabolic diseases. Methods: We described the relationship between obesity and inflammation, reviewed several signaling pathways in metabolic inflammation, and summarized some of the long non-coding RNAs and their targets associated with metabolic inflammation. The related studies were retrieved through a systematic search of the PubMed database. Result: Metabolic stress during obesity can cause inflammation through several metabolic pathways. Many long non-coding RNAs can affect the progression of metabolic inflammation by affecting different pathways. Conclusion: Downregulation or antagonization of long non-coding RNAs in metabolic pathways may provide new ideas and therapeutic targets for the prevention and treatment of metabolic inflammation.

scholarly journals Techniques of Eyebrow Lifting: A Narrative Review

2020 ◽  
Author(s):  
Mohsen Bahmani Kashkouli ◽  
Nasser Karimi ◽  
Hamed Sianati ◽  
Behzad Khademi
Keyword(s):  
English Language ◽  
Botulinum Toxin A ◽  
Forehead Lift ◽  
Search Terms ◽  
Brow Lift ◽  
Limited Effectiveness ◽  
Pubmed Database ◽  
Surgical Methods ◽  
Pros And Cons ◽  
Eyebrow Lift

None of brow lift techniques are completely satisfactory because of their limited effectiveness, lack of longevity, and potential complications. The aim of this study was to provide a comprehensive review of the literature on the pros and cons of the most popular techniques in brow and forehead lift. Relevant original articles in the PubMed database (English language) were sought using the search terms “eyebrow lift”, “forehead lift”, ”periorbital rejuvenation”, ”eyebrow ptosis”, ”blepharoplasty and eyebrow change”, ”surgical eyebrow lift”, and ”non-surgical eyebrow lift”, No date limitation was considered. Titles and abstracts were scanned to include the most pertinent articles. Subsequently, full texts of included articles (111 articles) were skimmed and finally 56 references were selected for the review. A narrative synthesis of data was finally undertaken with particular attention to the indications, techniques, and common complications of the eyebrow lift procedures. Ten popular techniques including two nonsurgical methods (Botulinum toxin A and soft tissue fillers) were reviewed in this article. In general, non-surgical methods of forehead/brow lift are temporary, need less experience and correction would be easier should any complication occur. Surgical methods are divided into three categories: trans-blepharoplasty eyebrow lift, direct eyebrow lift, and trans-forehead eyebrow/forehead lift. Currently, the most popular method is the endoscopic forehead lift approach even though its longevity is limited. Direct brow-lift is particularly useful in patients with facial palsy and those who are more likely to be accepting of the scar (male gender, high forehead hair line).

scholarly journals Selected Biomarkers of Tick-Borne Encephalitis: A Review

2021 ◽  
Vol 22 (19) ◽  
pp. 10615
Author(s):  
Monika Gudowska-Sawczuk ◽  
Barbara Mroczko
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Clinical Decision Making ◽  
White Blood Cells ◽  
Clinical Decision ◽  
Second Phase ◽  
Inflammatory Reactions ◽  
Tick Borne Encephalitis ◽  
Pubmed Database ◽  
The Central Nervous System

Tick-borne encephalitis (TBE) is an acute disease caused by the tick-borne encephalitis virus. Due to the viral nature of the condition, there is no effective causal treatment for full-blown disease. Current and nonspecific TBE treatments only relieve symptoms. Unfortunately, the first phase of TBE is characterized by flu-like symptoms, making diagnosis difficult during this period. The second phase is referred to as the neurological phase as it involves structures in the central nervous system—most commonly the meninges and, in more severe cases, the brain and the spinal cord. Therefore, it is important that early markers of TBE that will guide clinical decision-making and the choice of treatment are established. In this review, we performed an extensive search of literature reports relevant to biomarkers associated with TBE using the MEDLINE/PubMed database. We observed that apart from routinely determined specific immunoglobulins, free light chains may also be useful in the evaluation of intrathecal synthesis in the central nervous system (CNS) during TBEV infection. Moreover, selected metalloproteinases, chemokines, or cytokines appear to play an important role in the pathogenesis of TBE as a consequence of inflammatory reactions and recruitment of white blood cells into the CNS. Furthermore, we reported promising findings on tau protein or Toll-like receptors. It was also observed that some people may be predisposed to TBE. Therefore, to understand the role of selected tick-borne encephalitis biomarkers, we categorized these factors and discussed their potential application in the diagnosis, prognosis, monitoring, or management of TBE.

The Role of Radiation Therapy in the Treatment of Laryngeal Cancer

1984 ◽  
Vol 17 (1) ◽  
pp. 227-235
Author(s):  
Leslie E. Botnick ◽  
Christopher M. Rose ◽  
Izhak Goldberg ◽  
Abraham Recht
Keyword(s):  
Radiation Therapy ◽  
Laryngeal Cancer

The evolving role of pelvic radiation therapy

2003 ◽  
Vol 13 (2) ◽  
pp. 109-120 ◽  
Author(s):  
Terence Roberts ◽  
Mack Roach
Keyword(s):  
Radiation Therapy ◽  
Pelvic Radiation

Exercise in intensive care units, safety and hemodynamic monitoring

2020 ◽  
Vol 19 (1) ◽  
pp. 3
Author(s):  
Giulliano Gardenghi
Keyword(s):  
Intensive Care ◽  
Intensive Care Units ◽  
Hemodynamic Monitoring ◽  
Artificial Respiration ◽  
Exercise Physiology ◽  
Ventilatory Support ◽  
Early Mobilization ◽  
Cycle Ergometer ◽  
Search Terms

Introduction: Patients in the intensive care unit (ICU) have several deleterious effects of immobilization, including weakness acquired in the ICU. Exercise appears as an alternative for early mobilization in these patients. Objective: This work aims to highlight the hemodynamic repercussions and the applicability of exercise in the ICU. Methods: An integrative literature review was carried out, with articles published between 2010 and 2018, in the Lilacs, PubMed and Scielo databases, using the following search terms: exercise, cycle ergometer, intensive care units, early mobilization, mechanical ventilation, artificial respiration. Results: 13 articles were included, addressing hemodynamic monitoring and the role of exercise as early mobilization, with or without ventilatory support. The exercise sessions were feasible and safe within the ICU environment. Conclusion: Physical exercise can be performed safely in an ICU environment, if respecting a series of criteria such as those presented here. It is important that the assistant professional seeks to prescribe interventions based on Exercise Physiology that can positively intervene in the functional prognosis in critically ill patients.Keywords: exercise, intensive care units, patient safety.

ANALYSIS OF APPLICATION OF BLOCKCHAIN TECHNOLOGIES FOR THE BANKING SECTOR

2017 ◽  
Author(s):  
Svitlana Ilkovych ◽  
◽  
Maryna Korol ◽  
Keyword(s):  
Banking Sector ◽  
Blockchain Technology ◽  
Current State ◽  
Global Banking ◽  
Banking Institutions ◽  
Pros And Cons ◽  
Further Development

The article considers the essence of blockchain technology and the possibility of its application in the banking sector. The current state of development and application of blockchain technologies in various industries is analyzed. The pros and cons of using blockchain technologies for the banking sector are identified. Emphasis is placed on the role of blockchain technologies in the further development of the banking sector. The most promising directions of development of this technology are considered. Particular attention is paid to examples of the use of blockchain technology by global banking institutions.

Health and social problems associated with HIV infection and AIDS in the professional activity of specialists with secondary medical education

2020 ◽  
pp. 5-13
Author(s):  
L. Guseva
Keyword(s):  
Medical Education ◽  
Hiv Infection ◽  
Clinical Signs ◽  
Modern Society ◽  
Progressive Increase ◽  
Professional Activity ◽  
Infected People ◽  
Immunodeficiency Virus ◽  
Epidemiological Characteristics

The article considers urgent problem of modern society – progressive increase in the number of people infected with the human immunodeficiency virus (HIV). Epidemiological characteristics of the pathogen are given, clinical signs of the disease and a modern strategy aimed at reducing the number of infected people are presented. The role of specialists with secondary medical education in the implementation of the Strategy aimed at combating the spread of HIV infection epidemic in the Russian Federation is emphasized.

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