scholarly journals POTENSI TANAMAN MANGROVE SEBAGAI AGEN ANTIKANKER: LITERATURE REVIEW

2021 ◽  
Vol 10 (1) ◽  
pp. 12-16
Author(s):  
Widya Rahmah

Kanker merupakan suatu penyakit yang diakibatkan karena pertumbuhan yang tidak normal sel jaringan tubuh yang akan menjadi sel kanker. Penyakit kanker sampai saat ini masih merupakan salah satu penyakit yang menjadi problem dunia. Kanker menyebabkan kematian yang cukup besar, pada tahun 2018 tercatat 17 juta kasus kanker yang menyebabkan 9,5 juta kematian penduduk dunia disebabkan karena penyakit kanker. Indonesia tercatat sebagai negara yang memiliki jenis mangrove terkaya di dunia. Tumbuhan mangrove memiliki banyak sekali manfaat bagi kesehatan, salah satunya adalah sebagai antikanker. Tujuan dari penulisan literature review ini adalah untuk memberikan informasi dan gambaran mengenai kandungan metabolit sekunder dan senyawa bioaktif yang terdapat didalam tanaman mangrove, serta untuk mengetahui potensi tanaman mangrove sebagai agen antikanker. Pada penyusunan literature review ini digunakan suatu metode penelitian sekunder tanpa panduan tertentu dalam penulisannya (non-systematic review) yaitu metode pendekatan narrative review. Hal ini dilakukan dengan mengumpulkan data-data terkait  topik penelitian yang berasal dari berbagai pustaka elektronik dan non elektronik. Berdasarkan beberapa hasil penelitian, diketahui bahwa ekstrak tanaman mangrove memiliki aktivitas sitotoksik terhadap sel kanker myeloma dengan IC50 sebesar 508,19 μg/mL. Hasil isolasi senyawa squalene mempunyai efektivitas sebagai antikanker pada lambung dengan potensi aktivitas sitotoksik terhadap sel kanker MCF-7 dengan nilai IC50 masing-masing, yaitu 644,008 dan 595,164μg/mL.  Maka sangatlah sayang bila potensi ini tidak kita gali dan manfaatkan semaksimal demi kepentingan bersama. Banyak perguruan tinggi dan lembaga penelitian yang telah mengeksplorasi berbagai tumbuhan sebagai sumber obat namun belum banyak melirik khasiat pada tumbuhan mangrove.

Author(s):  
Camila Cristine Gomes Nazareth

RESUMO A pesquisa contou com um total de 57 (cinquenta e sete) trabalhos científicos que incluíram artigos científicos e editoriais de revistas científicas. Ao todo foram selecionados 28 (vinte e oito) trabalhos científicos com base no delineamento da pesquisa de revisão sistemática, sendo: 22 (vinte e dois) trabalhos científicos cujo eixo era a temática da revisão de literatura e 7 (sete) trabalhos científicos discutiam especificamente as diferenças e semelhanças entre revisão de literatura e revisão sistemática. Estes sete artigos serviram de base para o estudo no presente trabalho já que versam exclusivamente sobre o assunto. O objetivo do presente trabalho é realizar uma análise objetiva das diferenças entre a revisão de literatura comparada com a revisão sistemática de literatura. Palavras Chave: Revisão de Literatura; Revisão Sistemática; Revisão Narrativa  ABSTRACT A survey included a total of 57 (fifty-seven) scientific papers, including scientific articles and editorials from scientific journals. When 28 (twenty-eight) scientific papers were selected based on systematic review research, 22 (twenty-two) scientific papers focused on literature review and 7 (seven) scientific studies discussed as the similarities between literature review and systematic review. These seven articles served as the basis for the study in the present work since they deal exclusively with the subject.The objective of the present work is to carry out an objective analysis of the differences between a literature review compared to a systematic review. Key words: Literature Review; Systematic Review; Narrative Review


2019 ◽  
pp. 121-143
Author(s):  
Riccardo Resciniti ◽  
Federica De Vanna

The rise of e-commerce has brought considerable changes to the relationship between firms and consumers, especially within international business. Hence, understanding the use of such means for entering foreign markets has become critical for companies. However, the research on this issue is new and so it is important to evaluate what has been studied in the past. In this study, we conduct a systematic review of e-commerce and internationalisation studies to explicate how firms use e-commerce to enter new markets and to export. The studies are classified by theories and methods used in the literature. Moreover, we draw upon the internationalisation decision process (antecedents-modalities-consequences) to propose an integrative framework for understanding the role of e-commerce in internationalisation


Lupus ◽  
2020 ◽  
pp. 096120332096570
Author(s):  
Juliana P Ocanha-Xavier ◽  
Camila O Cola-Senra ◽  
Jose Candido C Xavier-Junior

Reticular erythematous mucinosis (REM) was first described 50 years ago, but only around 100 case reports in English have been published. Its relation with other inflammatory skin disorders is still being debated. We report a case of REM, including the clinical and histopathological findings. Also, a systematic review of 94 English-language reported cases is provided. The described criteria for clinical and histopathological diagnosis are highlighted in order to REM can be confidently diagnosed.


2020 ◽  
Vol 12 (7) ◽  
pp. 2702
Author(s):  
Alejandro Balanzo ◽  
Leonardo Garavito ◽  
Héctor Rojas ◽  
Lenka Sobotova ◽  
Oscar Pérez ◽  
...  

The paper aims to identify and analyze what types of governance challenges for sustainable regional development in the context of globalization are more frequently found in scholarship regarding Latin America. In order to do so, we carried out a systematic review of scholarly works discussing regional sustainability issues across the region. Analytically, it provides a heuristic multidimensional framework for organizing and typifying the most frequent sustainable regional development governance challenges under study, offering a nuanced and interrelated account of economic, environmental, political, and socio-spatial scientific discussions. According to our findings, scholarship on Latin America shows a bricolage-like scenery where political atomization linked to economic factionalism and fragmentation stand out as frequently analyzed situations. Another frequent topic relates to discussions about political endeavors linked to environmental concerns, connecting incidence strategies with collective environmental conservation approaches.


Author(s):  
Jan Schmidt ◽  
Martina Kunderova ◽  
Nela Pilbauerova ◽  
Martin Kapitan

This work provides a narrative review covering evidence-based recommendations for pericoronitis management (Part A) and a systematic review of antibiotic prescribing for pericoronitis from January 2000 to May 2021 (Part B). Part A presents the most recent, clinically significant, and evidence-based guidance for pericoronitis diagnosis and proper treatment recommending the local therapy over antibiotic prescribing, which should be reserved for severe conditions. The systematic review includes publications analyzing sets of patients treated for pericoronitis and questionnaires that identified dentists' therapeutic approaches to pericoronitis. Questionnaires among dentists revealed that almost 75% of them prescribed antibiotics for pericoronitis, and pericoronitis was among the top 4 in the frequency of antibiotic use within the surveyed diagnoses and situations. Studies involving patients showed that antibiotics were prescribed to more than half of the patients with pericoronitis, and pericoronitis was among the top 2 in the frequency of antibiotic use within the monitored diagnoses and situations. The most prescribed antibiotics for pericoronitis were amoxicillin and metronidazole. The systematic review results show abundant and unnecessary use of antibiotics for pericoronitis and are in strong contrast to evidence-based recommendations summarized in the narrative review. Adherence of dental professionals to the recommendations presented in this work can help rapidly reduce the duration of pericoronitis, prevent its complications, and reduce the use of antibiotics and thus reduce its impact on patients' quality of life, healthcare costs, and antimicrobial resistance development.


2021 ◽  
pp. 003151252110059
Author(s):  
Anne-Sophie Lamotte ◽  
Aziz Essadek ◽  
Gérard Shadili ◽  
Jean-Michel Perez ◽  
Julien Raft

Communication through discussion and conversations is fundamental to human life; but when such discourse escapes the control of a teacher in the classroom, it becomes little more than chatter. This noise challenges teaching methods and the teaching stance with students. Yet, its impact on comprehension has rarely been studied. The aim of this literature review was to examine the research on the impact of classroom noise generated by chatter on students’ comprehension performance. We adopted the PRISMA (Preferred Reporting Items for Systematic Reviews and Metanalysis) guidelines to examine this literature. This review covered a 10-year period (papers written between 2009 and 2019), with nine experimental studies selected from the 2,954 papers screened. In 89% of these nine studies, there were significant comprehension differences on all tests, revealed when comprehension took place in a noisy environment due to chatter. This review indicated an essential need for a field survey to better understand the impact of chatter on comprehension. Other studies are recommended to highlight any correlation between measured chatter and student comprehension in a real classroom environment.


2013 ◽  
Vol 21 (02) ◽  
pp. 123-151 ◽  
Author(s):  
MICHAEL LORZ ◽  
SUSAN MUELLER ◽  
THIERRY VOLERY

The majority of studies that analyze the impact of entrepreneurship education on entrepreneurial attitudes, intentions, and venture activities report positive influences. However, several scholars have recently cast doubts about research methods and the generalizability of entrepreneurship education impact studies. In this study, we conducted a systematic literature review of the methods used in entrepreneurship education impact studies. Our results uncover significant methodological deficiencies and question the overwhelmingly positive impact of entrepreneurship education. Based on this evidence, we propose a series of recommendations to improve the reliability and validity of entrepreneurship education impact studies and we outline promising topics which are currently under-researched.


2013 ◽  
Vol 18 (6) ◽  
pp. 100-105 ◽  
Author(s):  
Mariana de Aguiar Bulhões Galvão ◽  
Gladys Cristina Dominguez ◽  
Sérgio Thomaz Tormin ◽  
Alex Akamine ◽  
André Tortamano ◽  
...  

INTRODUCTION: Moyers analysis is widely used for analyzing mixed dentition, however, the accuracy of its theoretical probability tables has been recently questioned. Taking into consideration the fact the mixed dentition analysis is of paramount importance to precisely determine the space needed for alignment of canines and premolars, this research aimed at objectively assessing in the literature such an important step for orthodontic diagnosis. METHODS: A computerized search involving articles published on PubMed and Lilacs between 1990 and September, 2011 was conducted in accordance with the method described in the Cochrane 5.1.0 handbook. RESULTS: The research resulted in a sample composed of 629 articles. The inclusion criteria were: Articles using the Moyers analysis with a sample greater or equal to 40 patients. Conversely, the exclusion criteria were: Dental casts of patients with syndromes or oral cleft, researches conducted with a literature review, only, or clinical case reports and researches conducted before 1990. For this systematic review, 19 articles were selected. CONCLUSION: Based on the literature available, we can conclude that the Moyers mixed dentition analysis must be carefully used, since the majority of the articles analyzed showed that the probability of 75% was not as accurate as expected, leading to the need of adapting the probability levels depending on the study population.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Gonjin Song ◽  
Ji Yea Kim ◽  
Ha Young Yoon ◽  
Jeong Yee ◽  
Hye Sun Gwak

AbstractAlthough a considerable volume of data supporting induction or aggravation of psoriasis because of angiotensin-converting enzyme (ACE) inhibitor use exists, it remains insufficient for definitive conclusions. Therefore, we aimed to evaluate the association between ACE inhibitor use and psoriasis incidence through a systematic literature review and meta-analysis. We searched for qualifying studies across PubMed, Web of Science, and Embase. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to evaluate the strength of the association between ACE inhibitor use and psoriasis incidence. Eight studies with a total of 54,509 patients with a psoriasis diagnosis were included in this meta-analysis. The pooled OR for psoriasis incidence among ACE inhibitor users was 1.52 (95% CI, 1.16–2.00) compared to that among non-users. From subgroup analysis by continent, the OR for ACE inhibitor users versus non-users was 2.37 (95% CI 1.28–4.37) in Asia. Per the subgroup analysis by climate, the OR for ACE inhibitor users vs non-users in dry climate was 3.45 (95% CI: 2.05–5.79) vs 1.32 (95% CI 1.01–1.73) in temperate climate. Our results reveal a significant association between ACE inhibitor use and psoriasis incidence.


2021 ◽  
pp. 205789112110405
Author(s):  
Ikhsan Darmawan

Although the number of countries that have adopted e-voting has decreased lately, the number of academic publications on e-voting adoption has increased in the last two years. To date, there is no coherent narrative in the existing literature that explains the progress of the research on e-voting adoption. This article aims to answer the following research question: “How has research on the topic of e-voting adoption progressed over the last 15 years?” The article provides a semi-systematic review of 78 studies that were conducted from 2005 to 2020. In this article, I argue that although the studies on e-voting adoption are dominated by a single case study, by research in the United States, and by the positivist paradigm, scholars have employed the term “e-voting adoption” diversely and the research on e-voting adoption has evolved to address more specific research questions. Recommendations for the future agenda of research on e-voting adoption are also discussed.


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