scholarly journals Chorioptes texanus causing mange in goats: comparison of two therapeutic protocols

2021 ◽  
Vol 52 (4) ◽  
Author(s):  
Chaithanya Chandran ◽  
Biju P. Habeeb ◽  
Biju P. Habeeb ◽  
O. K. Sindhu ◽  
Janus A. ◽  
...  
Keyword(s):  
Clinical Symptoms ◽  
Leukocyte Count ◽  
Haemoglobin Concentration ◽  
Serum Glucose ◽  
Total Leukocyte Count ◽  
Skin Scraping ◽  
Treatment Protocols ◽  
Lime Sulphur ◽  
Perineal Region ◽  
Therapeutic Protocols

Out of 34 caprine dermatological cases examined, 12 were detected positive for Chorioptes texanus. Pruritus, alopecia, crusts, thickening, wrinkling, cracks and fissures on legs, axillae, inguinal region and perineal region were the symptoms noticed in caprine chorioptic mange. In affected animals, reduction in haemoglobin concentration and per cent lymphocytes were noticed, along with elevation in the values of the total leukocyte count, per cent neutrophils and per cent monocytes. Values of serum glucose, zinc and copper were normal. All the 12 cases were treated with ivermectin at 10 days interval till two consecutive skin scrapings were negative for mites. In addition, all goats were treated with vitamin A supplements throughout the period. Six goats were treated topically with permethrin spray while other six animals were treated topically with lime sulphur spray. Both treatment protocols caused recovery of the animals from clinical symptoms, however, a skin scraping after 1 year revealed the presence of mites.

Prevalence of uterine infection in relation to certain haematological and biochemical changes of blood serum in dairy cows

2016 ◽  
Author(s):  
B. Sarkar ◽  
K. Ray ◽  
U. Sarkar
Keyword(s):  
Blood Serum ◽  
Leukocyte Count ◽  
Biochemical Study ◽  
Serum Glucose ◽  
Biochemical Changes ◽  
The Body ◽  
Total Leukocyte Count ◽  
Control Group ◽  
Uterine Infection ◽  
Causative Agents

In the present study, blood samples of 79 cows with different uterine infections (pyometra, endometritis, cervicitis and abortion) and 41 normal cows of non-descripts and crossbreds were collected to study the prevalence of uterine infection in relation to haematological as well as biochemical changes in blood serum. In uterine infections, major infection remained endometritis which was recorded as highest (34.16%) followed by pyometra (18.33%), cervicitis (10.00%) and abortion (3.33%). Haematological study revealed a significant decrease in haemoglobin and total erythrocyte count while a significant increase in total leukocyte count in animals with uterine infection as compared to the control group. Biochemical study revealed that there was a severe decrease in serum glucose and serum cholesterol level in uterine infected cows in comparison to healthy cows. It was concluded that infection in the body, nature of the causative agents, and resistance of animal and localization of inflammatory response might be possible causes of lower biochemical parameters and haematological parameters except total leukocyte count in uterine infected cows.

scholarly journals Responses of Fluvalinate Induced Stress in Hematological and Biochemical Parameters of Lake van Fish (Alburnus tarichi guldenstadt 1814)

2001 ◽  
Vol 71 (3) ◽  
pp. 528-533
Author(s):  
Necati Ozok
Keyword(s):  
Leukocyte Count ◽  
Serum Glucose ◽  
Total Leukocyte Count ◽  
Control Group ◽  
Lake Van ◽  
Serum Enzyme ◽  
Lactate Dehydrogenase Activity ◽  
Glucose Levels ◽  
Induced Stress ◽  
Hematological And Biochemical Parameters

This research was conducted to determine the toxicity of fluvalinate to Lake Van fish (Alburnus tarichi) biometric, hematologic, and serum biochemicals. The fish were exposed to sub lethal fluvalinate concentration for 24, 48, 72 and 96 h for hematological and biochemical analyzes. Red blood cell, hemoglobin and hematocrit values decreased significantly in fish exposed to fluvalinate compared to control group. Significant increases in total leukocyte count were found. Compared with the control group, the serum enzyme aspartate aminotransferase, alanine aminotransferase, lactate dehydrogenase activity and serum glucose levels have increased significantly. This synthetic pyrethroid can be said to have a toxic effect on the Lake Van fish and can be used for controlling toxicity.

scholarly journals Peripheral blood and bone marrow responses under stress of cypermethrin in albino rats

2014 ◽  
Vol 7 (1) ◽  
pp. 33-40 ◽  
Author(s):  
Sunita Pande ◽  
Prabhu Narain Saxena ◽  
Brijender Bhushan ◽  
Nishi Saxena
Keyword(s):  
Bone Marrow ◽  
Peripheral Blood ◽  
Leukocyte Count ◽  
Haemoglobin Concentration ◽  
Total Leukocyte Count ◽  
Albino Rats ◽  
Differential Leukocyte Count ◽  
Corpuscular Haemoglobin ◽  
Mean Corpuscular Haemoglobin ◽  
Rbc Count

Abstract Pyrethroids, commercially available pesticides, are greatly in use these days, and thus they carry considerable chances of contaminating various ecosystems. Haematotoxicity of cypermethrin, a broadly used type II pyrethroid, has been assessed in the present study. Selected parameters included determination of total RBC count, haemoglobin concentration (Hb conc.), packed cell volume (PCV), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC), erythrocyte sedimentation rate (ESR), total leukocyte count (TLC), differential leukocyte count (DLC), along with qualitative analysis of blood and bone marrow. Of these parameters, those showing significant decline following cypermethrin intoxication included total RBC count, Hb conc., PCV, MCV, MCH, whereas non-significant decrease was observed in the case of MCHC. ESR, TLC and DLC, on the other hand, increased significantly following cypermethrin intoxication. Qualitative changes included altered red cell morphology such as microcystosis, appearance of stomatocytes, poikilocytosis, giant platelet formation, etc. in peripheral blood and increased erythroid precursors in bone marrow of treated rats. These parameters were however normalised following twenty-two days of recovery phase

scholarly journals Thermoregulation and Haematological Responses to Induced Acute Haemorrhage in Adult Nubian Goats

2019 ◽  
pp. 1-12
Author(s):  
Selma E. Abdalla ◽  
Abdalla M. Abdelatif ◽  
Shadia A. Omer
Keyword(s):  
Total Protein ◽  
Leukocyte Count ◽  
Venous Blood ◽  
Haemoglobin Concentration ◽  
Multiple Organ ◽  
Total Leukocyte Count ◽  
Serum Total Protein ◽  
Differential Leukocyte Count ◽  
Veterinary Haematology ◽  
Acute Haemorrhage

Background and Objectives: Acute haemorrhage is a major cause of morbidity and mortality in surgery and trauma due to ischaemic lesions followed by multiple organ dysfunction. After haemorrhage, compensatory redistribution of blood volume may occur to more vital and survival organs. The objective of the study was evaluation of thermoregulation and haematological responses to acute haemorrhage in Nubian goats. Materials and Methods: The study used 6 female mature goats, weighing 18.0 kg on average. The goats were subjected to 40% bleeding. The rectal temperature (Tr), respiration rate (RR) and heart rate (HR) were monitored before bleeding and then immediately after bleeding and at 1,2,3,4,5,6,24 hrs post-bleeding. Venous blood samples were collected before and then immediately after bleeding and at 6, 24, 48, 72 hrs post-bleeding. The haemoglobin concentration (Hb), packed cell volume (PCV), total leukocyte count(TLC), differential leukocyte count (DLC), serum total protein, albumin, and concentrations of sodium (Na) were determined. Results: The post-bleeding values of Tr, RR and HR were significantly higher compared to the pre-bleeding values. The post-bleeding values of PCV, Hb concentration, erythrocyte count and TLC were lower compared to prebleeding values. The ratios of lymphocytes, monocytes and eosinophils decreased, whereas the neutrophil ratio increased post-bleeding. The values of serum total protein, albumin and serum Na concentrations decreased post-bleeding. Conclusion: The studies indicate that the goat can be adopted as a valid research model in investigations of experimental haemorrhage. The findings have implications in the fields of veterinary haematology and surgery and comparative medicine.

scholarly journals Immune function during pregnancy varies between ecologically distinct populations

2020 ◽  
Vol 2020 (1) ◽  
pp. 114-128
Author(s):  
Carmen Hové ◽  
Benjamin C Trumble ◽  
Amy S Anderson ◽  
Jonathan Stieglitz ◽  
Hillard Kaplan ◽  
...  
Keyword(s):  
Leukocyte Count ◽  
Total Leukocyte Count ◽  
Future Research ◽  
Differential Leukocyte Count ◽  
Ecological Conditions ◽  
Trade Offs ◽  
The Usa ◽  
Immunological Changes ◽  
Fetal Antigens ◽  
Pathogen Exposure

Abstract Background and objectives Among placental mammals, females undergo immunological shifts during pregnancy to accommodate the fetus (i.e. fetal tolerance). Fetal tolerance has primarily been characterized within post-industrial populations experiencing evolutionarily novel conditions (e.g. reduced pathogen exposure), which may shape maternal response to fetal antigens. This study investigates how ecological conditions affect maternal immune status during pregnancy by comparing the direction and magnitude of immunological changes associated with each trimester among the Tsimane (a subsistence population subjected to high pathogen load) and women in the USA. Methodology Data from the Tsimane Health and Life History Project (N = 935) and the National Health and Nutrition Examination Survey (N = 1395) were used to estimate population-specific effects of trimester on differential leukocyte count and C-reactive protein (CRP), a marker of systemic inflammation. Results In both populations, pregnancy was associated with increased neutrophil prevalence, reduced lymphocyte and eosinophil count and elevated CRP. Compared to their US counterparts, pregnant Tsimane women exhibited elevated lymphocyte and eosinophil counts, fewer neutrophils and monocytes and lower CRP. Total leukocyte count remained high and unchanged among pregnant Tsimane women while pregnant US women exhibited substantially elevated counts, resulting in overlapping leukocyte prevalence among all third-trimester individuals. Conclusions and implications Our findings indicate that ecological conditions shape non-pregnant immune baselines and the magnitude of immunological shifts during pregnancy via developmental constraints and current trade-offs. Future research should investigate how such flexibility impacts maternal health and disease susceptibility, particularly the degree to which chronic pathogen exposure might dampen inflammatory response to fetal antigens. Lay Summary This study compares immunological changes associated with pregnancy between the Tsimane (an Amazonian subsistence population) and individuals in the USA. Results suggest that while pregnancy enhances non-specific defenses and dampens both antigen-specific immunity and parasite/allergy response, ecological conditions strongly influence immune baselines and the magnitude of shifts during gestation.

scholarly journals The mongolian gerbil: qualitative and quantitative aspects of the cellular blood picture

1975 ◽  
Vol 9 (4) ◽  
pp. 283-287 ◽  
Author(s):  
Walter G. Dillon ◽  
Chester A. Glomski
Keyword(s):  
Haemoglobin Level ◽  
Cell Volume ◽  
Mongolian Gerbil ◽  
Leukocyte Count ◽  
Absolute Number ◽  
Total Leukocyte Count ◽  
Red Cell ◽  
Blood Picture ◽  
Qualitative And Quantitative ◽  
Circulating Lymphocytes

The gerbil displays sex determined differences in packed red-cell volume, haemoglobin level, total leukocyte count and absolute number of circulating lymphocytes. The erythrocytes demonstrate a prominent polychromasia and frequent occurrence of basophilic stippling.

Outcomes of Peripheral Blood Eosinophilia in Hospitalized Exacerbations of COPD

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Samar El Sharkawy ◽  
Riham Hazem Raafat ◽  
Reem Osama Mohamed Ahmed Qassem
Keyword(s):  
Peripheral Blood ◽  
Diagnostic Performance ◽  
Leukocyte Count ◽  
Airflow Limitation ◽  
Total Leukocyte Count ◽  
Blood Eosinophil ◽  
Copd Exacerbation ◽  
Peripheral Blood Eosinophil ◽  
Copd Exacerbations ◽  
Cutoff Points

Abstract Background The Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines define COPD as a disease state characterized by airflow limitation that is not fully reversible, is usually progressive, and is associated with an abnormal inflammatory response of the lungs to inhaled noxious particles or gases. Objective To identify outcomes of patients with eosinophilic COPD exacerbations requiring hospital admission. Patients and Methods This study is a prospective cohort study that was conducted on two groups of total 60 patients recruited from Ain Shams University hospitals between October 2019 and July 2020. Group 1: Eosinophilic COPD exacerbation if the peripheral blood eosinophil on admission is ≥ 200 cells/µL and/or ≥2% of the total leukocyte count Group 2: Non-eosinophilic COPD exacerbation if the peripheral blood eosinophil on admission is < 200 cells/µL and/or < 2% of the total leukocyte count. Results There was significant high diagnostic performance in predicting readmission at 6-month among eosinophilic group. Eosinophils count, percent (%) and NLR cutoff points had high characteristics (highest in NLR ≥3.1 at discharge) in predicting readmission at 6-month among eosinophilic group. Diagnostic performance of Eosinophils count, percent (%) and NLR were assessed. Eosinophils count, percent (%) and NLR had significant high diagnostic performance in predicting readmission at 6-month among eosinophilic group. Eosinophils count, % and NLR cutoff points had high characteristics (highest in NLR ≥2.1 at discharge) in predicting readmission at 6month among non-eosinophilic group. Conclusion Eosinophils can be used as a prognostic marker in non-infective COPD exacerbations. Validity of eosinophil count and percent as a prognostic parameter in COPD exacerbation can be increased by combining with other parameters for example NLR.

Utility of Blood Markers in Early Prediction of Bacteraemia in Acute Febrile Paediatric Patients – An Observational Cohort Study in a Tertiary Care Hospital of North India

2021 ◽  
Vol 8 (28) ◽  
pp. 2526-2531
Author(s):  
Rabindra Bhunia ◽  
Bindu T. Nair ◽  
Vandana Negi
Keyword(s):  
Tertiary Care Hospital ◽  
Leukocyte Count ◽  
Tertiary Care ◽  
North India ◽  
Total Leukocyte Count ◽  
Care Hospital ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Neutrophil Percentage ◽  
Observational Cohort

BACKGROUND Bacteraemia is a common cause of children presenting to the paediatric emergency with acute febrile illness. Blood cultures remain the gold standard for detection of bacteraemia but the positivity is low and also takes time to show positive results. A rapid and reliable biomarker like procalcitonin (PCT), C-reactive protein (CRP), total leucocyte count (TLC), and neutrophil-lymphocyte count ratio (NLCR) can be used to identify febrile children with greater risk for bacteraemia or serious bacterial infections. This would be very helpful to start early treatment of bacteraemia with antibiotics. METHODS The study was an observational cohort study conducted in the Department of Paediatrics of a tertiary care hospital in North India in children between age group 6 months to 12 years presenting with fever of > 100.4° F for 2 - 7 days. Blood samples were sent for PCT, CRP, TLC, NLCR and blood cultures. RESULTS The most sensitive biomarker was total leukocyte count (47.36 %) followed by the neutrophil percentage (26.32 %), C-reactive protein (21.05 %), and procalcitonin (15.79 %). The most specific biomarker was procalcitonin (75.14 %) followed by C-reactive protein (58.56 %), neutrophil percentage (22.65 %) and total leukocyte count (11.05 %). The only biomarker that was statistically significant between the bacteraemia and non-bacteraemia group in the present study was total leukocyte count (P – value < 0.05). CONCLUSIONS The sensitivity and specificity of each single biomarker is low and hence these cannot be used singly to predict bacteraemia. There should be a combination of biomarkers with adequate sensitivity and specificity that can be used to create an algorithm to aid in diagnosis and prognostication. KEYWORDS Procalcitonin, C-Reactive Protein, Blood Culture, Acute Febrile Patient

scholarly journals CORRELATION OF TOTAL LEUKOCYTE COUNT AND PLATELETS WITH THE RECOVERY PHASE IN CHILDREN WITH DENGUE ADMITTED IN AN URBAN TERTIARY CARE CENTER

2019 ◽  
Vol 6 (6) ◽  
pp. 295-299
Author(s):  
Nishikant Kotwal ◽  
Milind Mandlik ◽  
Sachin Daharwal ◽  
Kamble Taposhi ◽  
Abhishek Madhura ◽  
...  
Keyword(s):  
Leukocyte Count ◽  
Care Center ◽  
Tertiary Care ◽  
Recovery Phase ◽  
Total Leukocyte Count ◽  
Tertiary Care Center
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