scholarly journals An attempt to understand the concept of PCOS w. s. r. to artavavaha sroto dusti

Author(s):  
Dharmaraj Nagorao Lone ◽  
Chitra Gawande ◽  
Pratibha Kulkarni ◽  
Nagorao Dattarao Lone

Polycystic ovarian syndrome (PCOS) is the most common endocrine ovarian disorder affecting 5 to 10% women of reproductive age. It is also known as stein- laventhal syndrome or hyper androgenic Anovulation. The main primary character of PCOS is irregular menstrual cycle which leads to improper ovulation. Exact pathogenesis of PCOS is not understood clearly, it may be discussed under following headings: Abnormality of Hypothalamic-pituitary compartment (Hormonal imbalance), androgen excess, anovulation, obesity and insulin resistance etc. Srotas are the circulatory channels through which Dosha’s, Dhatu’s and Mala’s moves from one part to another part of the body. Each srotas has srotomoola, srotomarga and srotomukha. The moolasthana of artavavaha srotas are garbhashaya(uterus) and artavavahi dhamani’s(uterine & ovarian arteries). Artavavaha srotas may be categorized into Shonita artavavaha srotas which carries menstrual blood through blood vessels and capillaries of the uterus & Beejartavavaha srotas which carries ovum through fallopian tubes. Abnormality of Artavavaha srotas causes Vandhyatva, Maithuna Asahishnuta and Artavanasha. Vandhyatva caused due to abnormality in chaturvidha garbhottpadaka(rutu, kshetra, ambu and beeja) samagri. Maithuna Asahishnuta related to vatala, paripluta, vipluta and shandi yoniyapada, while Artavanasha related to Vandhya, Arajaska and shushka yonivyapada. All these symptoms like Vandhyatva, Maithuna Asahishnuta and Artavanasha are correlated with common symptoms of PCOS which include Infertility, Dyspareunia & Amenorrhoea respectively. As there is no curative treatment available in modern medicine, understanding of PCOS with reference to Artavavaha sroto dusti may be a ray of hope to treat PCOS with Ayurvedic remedies. KEY WORDS: Artava, Srotas, PCOS, Vandhyatva, Yonivyapada.

Author(s):  
Oluwatoni D. Adebisi ◽  
Blessing C. Denwigwe-aggrey ◽  
Ashiat Bolanle Tairu ◽  
Ngozichukwu Ozoemena ◽  
Joy F. David ◽  
...  

Polycystic ovary syndrome (PCOS) is defined as a hormonal disorder that is prevalent among women of reproductive age. It affects the metabolic, endocrine, and reproductive systems of the body as well as mental health. We compared up to 20 peer-reviewed literature that displayed the relationship between PCOS and mental health. We searched the PMC/NCBI/NIH database and we used the following keywords while searching the database: "polycystic ovarian syndrome" or "PCOS" and "mental health" or "depression" or "anxiety" or "low self-esteem" were included in the search for articles. Women of reproductive age are seen to be affected by PCOS. The effect of polycystic ovarian syndrome on the mental health of women of reproductive age has serious complications. Complications include an increased rate of anxiety and depression in the individual. When there is an increase in depression and anxiety, it tends to affect the physical changes and the confidence of women with PCOS. PCOS has been proven to be incurable but its symptoms can be managed. PCOS is linked with mental health and it has serious implications on the psychological health of the individual. Management of PCOS should include an early assessment of the patients’ mental health. If required, medications for mental health improvement should be prescribed in addition to medication for treating the physical and biochemical symptoms of PCOS. 


Author(s):  
Rajashree Panigrahy ◽  
Bratati Singh ◽  
Tapan K. Pattnaik ◽  
Sanjukta Misra

Background: Ovarian androgen production can be promoted by insulin resistance which leads to reproductive abnormalities in Polycystic Ovarian Syndrome (PCOS). A wide variety of female tissues can synthesize and secrete Prostate Specific Antigen (PSA). Androgens may take part a significant role in PSA secretion in PCOS. As insulin resistance stimulates androgen production, the baseline value of PSA may decline by insulin sensitising agents in PCOS. Present study is an attempt to measure the function of PSA as a marker of androgen excess in PCOS and to assess the role of insulin sensitising agent metformin in altering PSA level in PCOS.Methods: The study was undertaken to assess the insulin resistance, testosterone and PSA level in 45 women diagnosed as PCOS and 45 healthy controls. Alteration of insulin resistance, serum testosterone and PSA levels by metformin was also analysed.Results: A significant increase in testosterone, PSA level and insulin resistance was observed in PCOS cases when compared with control (p<0.001). When metformin was given for 4 months, improvement in insulin resistance and testosterone level was found in cases, but PSA values observed no change. Correlation was not found linking insulin resistance with PSA level prior to and after therapy.Conclusions: Serum PSA level could be detected in high significant concentration in PCOS women. Various researches explain that insulin resistance and BMI may perhaps control serum PSA level, but our result demonstrate no effect of insulin sensitising agent on serum PSA value.


2020 ◽  
Vol 11 (4) ◽  
pp. 644-649
Author(s):  
Saroj Kumari ◽  
Sarvesh Kumar Singh ◽  
Kshipra Rajoria ◽  
Avadhesh Kumar

Polycystic ovarian syndrome (PCOS) is a probably fastest growing endocrinological disorder in females of reproductive age. In PCOS, follicular growth is influenced by hormonal imbalance during the ovarian cycle, leads to affected follicles remain in the ovary. The prevalence of PCOS is estimated 6-10% globally and 3.7% - 22.5% in Indian female population, which is relatively high. It is characterised by hyperandrogenism, anovulation and polycystic ovaries which clinically manifests in the terms of amenorrhea or oligomenorrhea, hirsutism, acne, infertility etc. In present scenario, incidence of this disease increasing exponentially due to sedentary lifestyle and faulty dietary habits. This particular disease is not described word to word in Ayurveda. Associated features of PCOS are closely resembling with Bandhya Yonivyapada, Artavavahasrotasa-Vidhha Lakshana, Nastartava and Ksheenaartava described by Acharya Sushruta and Pushpghani Jatharini and Vikuta Jatharini mentioned by Acharya Kashyap. Maximum congruence of PCOS can be established with Bandhya Yonivyapada. The purpose of this study is to understand Nastartava which is the cardinal feature of Bandhya. Word Artava has been used exclusively in Samhita in context of menstrual blood, ovum and ovarian hormones. Therefore Amenorrhea, anovulation, hormonal dysfunction is considered exposed manifestations of Nastartava. Possible line of treatment is stipulated with Nidanaparivarjan, herbal drugs and Panchakarma procedures. Keywords- Ayurveda, Artava, Nastartava, PCOS, Herbal drugs, Panchakarma


Author(s):  
Chaitali Maitra ◽  
Ramesh Chandra Gupta ◽  
Rishika Raj

Introduction: Polycystic Ovarian Syndrome (PCOS) is a common endocrine disorder in the women of reproductive age. Studies show that there is an intensive relationship between insulin and gonadal function. As per Rotterdam Criteria, there are four major phenotypes of PCOS with different presentation. Early detection of Insulin Resistance (IR) and consequential prevention of Metabolic Syndrome (MS) associated with PCOS may lead to better prospect for the disease. Aim: To find the pattern of IR in all the phenotypes of PCOS in relation to Waist Hip Ratio (WHR), Body Mass Index (BMI) and Testosterone and thereby, providing data for designing phenotype specific treatment of the disease. Materials and Methods: In this cross-sectional observational study, fasting insulin and fasting glucose were analysed to calculate Homeostasis Model Assessment (HOMA-IR) and Testosterone for total 144 female subjects of reproductive age group (18-40 years). Subjects were classified in to four groups as per Rotterdam Criteria. Complete PCOS (PCO-COM), PCO with Oligo/Anovulation (PCO-O), Anovulation with Hyperandrogenism (O-HA), and PCO with Hyperandrogenism (PCO-HA). Regression analysis was done to find the relation among the study variables. Analysis of Variance (ANOVA) was used to analyse the significant variance among the groups. Results: IR was found to be maximum among O-HA phenotype (2.4±0.37) and lowest among PCO-HA phenotypes (1.3±0.22). Regression analysis shows that there exist significant associations between IR and BMI (t=4.96, p=0.001) as well as between IR and WHR (t=2.97, p=0.003). No independent association between testosterone and IR was observed. Conclusion: Significant difference of IR, WHR, and BMI was observed among the four phenotypes of PCOS. Due to increased IR, O-HA and PCO-COM phenotypes are more predisposed to Cardiometabolic consequences of PCOS.


2017 ◽  
Vol 19 (1) ◽  
pp. 49-53
Author(s):  
Rabia Farooq

Polycystic ovarian syndrome (PCOS) is a metabolic disease and a common endocrine system disorder among women of reproductive age. Infrequent or prolonged menstrual periods, excess hair growth, acne, and obesity can occur in women with PCOS. Early diagnosis and treatment along with weight loss may reduce the risk of long-term complications. Now a days PCOS is also the cause of infertility. India is PCOS capital of the world. PCOS management is necessary to reduce its long time complications.J MEDICINE Jan 2018; 19 (1) : 49-53


Author(s):  
Sukhleen Kaur ◽  
Sunil K. Gupta ◽  
Sunil K. Juneja ◽  
Sukhjot Kaur ◽  
Monika Rani

Background: Polycystic ovarian syndrome (PCOS) is one of the most frequently encountered endocrine disorders that occurs in as many as 4 to 10% of women of reproductive age group. It presents with a series of skin changes including acne, hirsutism, seborrhea, androgenetic alopecia (AGA) and acanthosis nigricans. Aim of the study was to determine the prevalence and frequency of different cutaneous manifestations in PCOS patients and to correlate them with the degree of hormonal abnormalities.Methods: A total 100 patients with features of PCOS who presented to department of dermatology, gynecology (January 2018-December 2019) with cutaneous manifestations were recorded and diagnosis of PCOS was made using Rotterdam’s criteria. Pregnant women and diagnosed cases of any other endocrine disorder were excluded. Hirsutism was assessed using Ferriman-Gallwey score and AGA according to Ludwig’s classification. Serum hormonal profile including FSH, LH, prolactin, testosterone (free), DHEAS, TSH, FBS, fasting insulin were done. Insulin resistance was determined by calculating HOMA-IR score.Results: Among cutaneous manifestations of PCOS, hirsutism (85%) was the most common finding followed by acne (73%), seborrhea (50%), AGA (36%), acanthosis nigricans (29%) and acrochordons (9%). The most common hormonal abnormality was insulin resistance in 53% patients, followed by raised free testosterone in 19% and serum prolactin in 18% patients. A statistically significant association was present between AGA and insulin resistance, hirsutism and raised prolactin levels, seborrhea and raised body mass index (p < 0.05).Conclusions: Dermatological manifestations of PCOS play a significant role in making the diagnosis and constitute a substantial portion of the symptoms experienced by women with this syndrome.


Author(s):  
Najma Malik ◽  
Navneet Dubey

Background: PCOS is one of the most common endocrine disorder in women of reproductive age, it affects about 5-10% of women of reproductive age. It is characterized by chronic anovulation, hyperandrogenism, and insulin resistance. 30-40% of PCOS women have impaired glucose tolerance.Methods: This was prospective observational study carried out on 100 patients of PCOS visiting outpatient Department of Obstetrics and Gynecology, BRD Medical College, Gorakhpur from 1st July 2018 to 30th June 2019. Patients were diagnosed as PCOS on basis of Rotterdam criteria. In these 100 patients, oral inositol 2 gm twice daily was given for 3 months to 6 months depending upon the response of the patient and patients were examined every 4 week for menstrual regularity, acne improvement, hirsutism, spontaneous ovulation and pregnancy.Results: With inositol supplementation, menstrual abnormality corrected in 80% cases, 45% cases having acne improved. Ovulation occurred in 75.5% cases and 66.6% cases conceived with inositol supplementation.Conclusions: Insulin resistance is the basic pathophysiology for PCOS hence inositol supplementation is supposed to be very good medicine for management of PCOS to improve insulin sensitivity. Inositol leads to improvement in regularity of menstrual cycle, insulin resistance, hyperandrogenic features like hirsutism, acne, restores ovulation and improves oocyte quality.


2018 ◽  
Vol 7 (2) ◽  
pp. 118-122
Author(s):  
A. Saravanan ◽  
S. Sathiamoorthy

Polycystic Ovarian Syndrome is an endocrine ailment affecting women of reproductive age. This syndrome is largely found in women whose age is in between 25 and 35. Without knowing the accurate region of a follicle in ovary, the hazard rigorousness of the patient cannot be exposed. Since, super-pixels can be functional on segmentation and image representation, it has turned out to be essential for refining the competence in computer vision systems. Thus, in this paper, a novel image denoising methodology for the detection of a follicle in the PCOS has been suggested by exploring the super-pixel clustering and Fuzzy C means clustering.


2017 ◽  
Vol 9 (4) ◽  
pp. 341-347
Author(s):  
Rekha R Madusudhanan ◽  
Bindu Nambisan ◽  
Mayadevi Brahmanandan ◽  
Sreekumari Radha

ABSTRACT Introduction Polycystic ovarian syndrome (PCOS) is an endocrine disorder affecting all age groups and presenting with myriad problems like menstrual irregularities, hirsutism, anovulatory infertility, and long-term complications like diabetes, cardiovascular problems, etc. Aim Study was aimed at finding the prevalence, characteristics, and various risk factors of metabolic syndrome (MS) in reproductive age group in our hospital. Materials and methods Using statistical table, a sample size of 131 was calculated and patients were recruited as per inclusion criteria. Polycystic ovarian syndrome was diagnosed by the American Society for Reproductive Medicine (ASRM)/European Society of Human Reproduction and Embryology (ESHRE) criteria. After informed consent, a detailed history was obtained and physical examination was carried out to assess, body weight, height, body mass index (BMI), waist—hip ratio (WHR), and blood pressure (BP). Fasting blood glucose, triglycerides, and high-density lipoprotein (HDL) were measured for each woman Results Prevalence of MS in our study was 45.8%; 26.7% of patients had a combination of increased waist circumference, raised triglycerides, and low HDL; 55.2% of patients had a fasting blood sugar (FBS) levels more than 100 mg%. Age of the patient was a statistically significant risk factor of MS with 100% of patients in the age group of 35 to 39 presenting with MC. Body mass index was also a statistically significant risk factor with 82.6% with BMI > 30 having MC. Other important risk factors include a WHR more than 0.95, presence of diabetes in mother or sister, and presence of acanthosis; 71% of patients with WHR more than 0.95 had MC. Age of menarche, duration of menstrual cycles, and hirsutism showed no significant relationship. Conclusion An outstanding fact that emerged in this study was that 94% of women with PCOS had HDL values <50 mg/dL. And 58% had triglycerides more than 150 mg/dL. Hence, lifestyle modification and early intervention will hopefully spare long-term complication of PCOS. How to cite this article Madusudhanan RR, Nambisan B, Brahmanandan M, Radha S. Study on the Prevalence and Characteristics of Metabolic Syndrome in Women of Reproductive Age Group with Polycystic Ovarian Syndrome. J South Asian Feder Obst Gynae 2017;9(4):341-347.


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