scholarly journals Analysis of main statistical indicators of oral and pharyngeal cancer in the Republic of Uzbekistan

2021 ◽  
Vol 62 (4) ◽  
pp. 4-8
Author(s):  
J. Alimov ◽  
N. Karimova

Relevance: According to GLOBOCAN data for 2020, oral and pharyngeal cancer ranked 25th in mortality (98 412 cases, 0.5% of all cancer deaths) and 26th in the number of diagnosed new cases (48 143 cases, 0.5% of all new cancer cases) in the world. Oral and pharyngeal cancer incidence is growing steadily globally and in the Republic of Uzbekistan. Oral and pharyngeal cancer ranks 16th in the structure of cancer incidence in the Republic of Uzbekistan, with a rate of 1.8 per 100 000 people. The purpose of the study was to analyze the main statistical indicators for tumors of the oral cavity and pharynx in the Republic of Uzbekistan in 2015-2021. Methods: We analyzed the main statistical indicators for tumors of the oral cavity and pharynx in the Republic of Uzbekistan for 2015- 2020 obtained from the Reporting Form #7 “Information about malignant neoplasms cases.” Results: Over the past six years, the incidence rate per 100,000 people has increased from 1.4 in 2015 to 1.8 in 2020. In 2015-2020, in the Republic of Uzbekistan, 2,240 patients died from malignant neoplasms of the oral cavity and pharynx. The mortality rate per 100,000 people decreased from 1.4 in 2015 to 1.2 in 2020. Conclusions: Tumors of the oral cavity and pharynx rank 16th in the structure of cancer incidence in the Republic of Uzbekistan and tend to grow. A recent increase in oral and pharyngeal cancer incidence and its late detection could be explained by worsening detection and diagnostics. The stabilization of oral and pharyngeal cancer mortality results in socio-economic losses for the Republic. The provided statistical data is the basis for improving the indicators of incidence and mortality related to oral and pharyngeal cancer in the Republic of Uzbekistan

2020 ◽  
Vol 147 (4) ◽  
pp. 1040-1049 ◽  
Author(s):  
Cristina Bosetti ◽  
Greta Carioli ◽  
Claudia Santucci ◽  
Paola Bertuccio ◽  
Silvano Gallus ◽  
...  

2021 ◽  
Vol 23 (2) ◽  
pp. 155-164
Author(s):  
Vladislav E. Moiseenko ◽  
Alexander V. Pavlovsky ◽  
Dmitry A. Granov ◽  
Larisa V. Kochorova ◽  
Inna V. Dodonova ◽  
...  

Morbidity and mortality from pancreatic cancer is an urgent medical and social problem. Evaluation of statistical indicators in dynamics makes it possible to identify organizational and clinical problems in providing care to patients with malignant neoplasms of the pancreas. Medical and statistical indicators of incidence of malignant pancreatic neoplasms in St. Petersburg residents are evaluated. The assessment of medical and statistical indicators of the incidence of malignant neoplasms of the pancreas in residents of St. Petersburg. Statistical data were studied for the period from 2014 to 2019. The increase in the "rough" indicator of primary morbidity changed from 417.99 per 100 thousand population in 2014 to 505.6 in 2019. In the structure of primary cancer incidence, the indicator of active detection of pancreatic cancer glands in 2014 amounted to 3.6%, in 2019 3.8%. The proportion of patients with diagnoses confirmed morphologically increased from 48.9% to 61.4%. The proportion of patients with newly diagnosed stage IV of the disease changed from 39.5% in 2014 to 51.4% in 2019, and in patients with stage III in 2019 it was 33.3% (a decrease in comparison with 2014 15.3%). In 2019, the disease was diagnosed at stage II in 15.2% of patients. The proportion of patients with stage I in 2019 was 6.6%, this indicator in 2014 was registered at the level of 19.2%. From 2014 to 2019, the one-year mortality rate did not change and amounted to 67.9 and 67.4%, respectively (the decrease was 0.7%). Over the past 5 years, there has been no significant downward trend in the "rough" incidence and mortality rates from pancreatic cancer. However, in the dynamics, there was an increase in the number of patients registered for 5 or more years, and an increase in the accumulation index of the contingent of patients with pancreatic cancer.


Author(s):  
E. S. Sedova ◽  
V. I. Jusupov ◽  
N. N. Vorobieva ◽  
N. V. Kanischeva ◽  
A. A. Chernyavskii ◽  
...  

Low-level laser therapy as a method for correcting the mucositis caused by ionizing radiation of the oral mucosa is used in clinical practice for various exposure parameters: radiation power not less than 10 mW, laser doses not less than 2 J/cm2. The purpose of this study was to compare the efficacy of low-level laser therapyred and infrared laser radiation for the correction of mucositis of the oral mucosa in patients receiving radiation and chemoradiotherapy for oral and pharyngeal cancer, with laser doses of less than 1 J/cm2. The study included 106 patients who received radiation and chemoradiotherapy for cancer of the oral cavity and pharynx, which were randomly divided into three groups. In the first (37 patients), mucositis was prevented and corrected in accordance with the standards of the clinic, in the second (36 patients) and the third (33 patients), patients were additionally exposed to the oral cavity with Low-level laser therapy (LLLT) at 635 nm and 780 nm at powers of 5 mW and 20 mW, respectively. The effect of LLLT on the wavelength of 635 nm significantly reduced the frequency and severity of mucositis, increased the time until the appearance of the first symptoms of mucositis of the oral mucosa, shortened the duration of severe mucositis (grade 3), and reduced the need for painkillers, including narcotic analgesics compared with the group who received standard prophylaxis and correction of mucositis.


Vestnik NSUEM ◽  
2019 ◽  
pp. 208-219
Author(s):  
N. I. Ovechkina ◽  
E. S. Shmarikhina

The article reflects the problems of solving theoretical and methodological issues of the statistical research of demographic security. In order to justify the system of statistical indicators of the demographic security, considered regional differences in the incidence of socially significant diseases:tuberculosis, HIV infections, malignant neoplasms, mental disorders, psychotic disorders associated with alcohol use and alcohol dependence syndrome, syphilis. Groups of subjects of the Russian Federation with the maximum and minimum values of indicators are allocated and shown on the map. The most socially prosperous regions in Russia are the Republic of Dagestan, the Chechen Republic, the Republic of Kalmykia, the Republic of Ingushetia and the Belgorod region, the Irkutsk region and the Chukotka Autonomous Okrug were the absolute Champions in terms of social disadvantage in 2018.


2021 ◽  
Vol 58 (4) ◽  
pp. 4-11
Author(s):  
D. KAIDAROVA ◽  
O. SHATKOVSKAYA ◽  
Z. DUSHIMOVA

Relevance: Cancer control is among the key social policy priorities in the Republic of Kazakhstan. 14,000 people die from cancer every year. As a result, our country faces an epidemiologic crisis caused by the increasing malignancy-related incidence and mortality, plus the increasing number of people living with cancer. In 2019, 186 326 patients with malignant neoplasms were under dynamic supervision in Kazakhstan; 52.5% lived for five years or more [1]. WHO prognosis a 1.5-2 times growth of annual malignancy-related incidence and mortality worldwide by 2022. The Republic of Kazakhstan follows the same trend, taking into account the growing welfare and life expectancy of the population and an increase in the detection of malignant neoplasms due to the introduction of early detection programs [2]. This study aimed to assess the implementation in 2019 of the Comprehensive Cancer Control Plan in the Republic of Kazakhstan for 2018-2022. Results: Intermediate Comprehensive Plan implementation results showed the efficacy of the conducted measures as reflected by major cancer service indicators. Thus, the early detection has improved: stage 0-I detection amounted to 27.1% of all new cases (2019 target – 25.2%). This had a positive impact on cancer survival: in 2019, the proportion of 5-year or more survival was 54.7% for breast cancer (2019 target – 54.5%), 56.8% for cervical cancer (2019 target – 55.8%), 46.6% for colorectal cancer (2019 target – 45.8%) [1]. Conclusion: The Comprehensive Cancer Control Plan implementation results evidence cancer service improvement in the Republic of Kazakhstan as of 2019 (increased 5-year survival and decreased mortality). However, a high share of detection of visually accessible malignant neoplasms at generalized and advanced stages should be addressed in the coming years.


2020 ◽  
Vol 55 (1) ◽  
pp. 12-15
Author(s):  
K. TOLEUTAIULУ ◽  
A. ZHYLKAYDAROVA ◽  
U. ZHUMASHEV ◽  
S. YESSENKULOVA ◽  
A. JAKIPBAYEVA ◽  
...  

Relevance: Esophageal cancer ranks eighth in the structure of malignant tumors in the Republic of Kazakhstan. According to the Kazakh Institute of Oncology and Radiology, in 2018, 1225 were primarily registered with esophageal cancer, and 825 patients died from this disease. The purpose of this study was to analyze the esophageal cancer incidence and mortality among the population of the Republic of Kazakhstan in 2009-2018 and determine the cancer service efficacy. Results: The analysis of intensive indicators of esophageal cancer incidence showed a decrease in the number of primary cases from 8.2‰ in 2009 to 6.7‰ in 2018, and the mortality – from 6.9‰ to 3.8‰. The share of early detection (Stage I-II) increased by 38.2% since 2009 to reach 52.1% in 2018. The share of stage IV esophageal cancer decreased from 7.2% in 2009 to 5.8% in 2018. One-year mortality decreased by 14.7% since 2009 to reach 41.2% in 2018, which speaks of the improvements in the timely diagnosis of esophageal cancer. The number of patients who received radical comprehensive treatment increased by 8.6% to reach 32.2% in 2018. The number of patients who received surgical treatment in 2009-2018 remained almost at the same level and amounted to 18.9 and 18.0%, respectively. However, during the years of screening for esophageal cancer, the proportion of surgical treatment increased from 26.6% to 30.4%. The ratio of incidence to mortality decreased from 91.4% to 68.8% in the study period indicating an improvement in the level of cancer service in the Republic of Kazakhstan. Conclusion: The analysis of intensive indicators of esophageal cancer incidence showed a decrease in primary incidence. The screening conducted in 2013-2016 has shown an improvement in early detection of esophageal cancer (stages I-II) and a decrease in the share of the advanced stage. The findings of this study shall serve as the basis for planning anti-cancer measures


Author(s):  
АА Kovshov ◽  
YuA Novikova ◽  
VN Fedorov ◽  
NA Tikhonova ◽  
OA Istorik

Introduction: Extensive measures are taken in the Russian Federation to reduce cancer incidence and mortality in the population but the proportion of incident cases in advanced stages is still large while correct registration of deaths and diseases remains a challenge. Our objectives were to study the incidence of malignant neoplasms in the Leningrad Region, to establish territories at risk, and to analyze carcinogenic risk factors associated with environmental conditions in these territories. Materials and methods: We used data of the Federal Statistical Observation Forms No. 7 “Information on Malignant Neoplasms”, No. 12 “Information on the Number of Diseases Registered in Patients Living in the Service Area of a Medical Organization”, No. 18 “Information on the Sanitary Condition of the Subject of the Russian Federation”, and information on the size of population by sex and age in the Leningrad Region and its districts for 2008–2018. We applied a direct method of standardizing incidence rates by age, analyzed the dynamics of incidence, and estimated statistical significance of differences in the incidence rates between the territories of comparison. Results: Cancer incidence in the Leningrad Region was lower than that in Russia. In 2008–2018, the highest rates were registered in the Kirishsky and Podporozhsky districts. In the Podporozhsky district, the standardized incidence rate in 2018 was 328.1 cases per 100,000 population or 1.79 times higher than the regional average, while the average rate for 2008–2018 exceeded the regional average by 1.36 times. The Kirishsky district ranked second by the incidence of malignant neoplasms in the Leningrad Region in 2018 (241.4 cases per 100,000 population or 1.32 times higher than the regional average), while the average rate for 2008–2018 exceeded the regional one by 1.47 times. Conclusions: Additional research is necessary to establish the causes of high cancer incidence rates in the Kirishsky and Podporozhsky districts of the Leningrad Region.


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