scholarly journals Epidemiology of benign and malignant tumors in children in the Republic of Moldova (1 year of activity-2020)

Author(s):  
Gheorghe Tibirna ◽  
◽  
Eva Gudumac ◽  
Ion Mereuta ◽  
Silvia Railean ◽  
...  

The work was carried out within the State Program (1 year of activity-2020); „Modern personalized surgery in the diagnosis and complex treatment of tumors in children” N. 20.80009.8007.06. Analyzing the statistical data during the first year of activity of the project were registered 777 children with tumors, of which 279 (35.2%) primary and 498 (64.8%) – secondary. Of the 777 children, 455 (58.5%) had benign tumors and 97 (12.4%) had malignancies, 231 (29.7%) patients underwent surgical treatment, 455 (58.5%) chemotherapeutic treatment, 13 (1.9%) radiotherapy. Since March 2020, we have been active under the SARS-CoV-2 pandemic. We have developed a special proce- dure for the prevention of coronavirus infection. The COVID-19 pandemic is a new situation, unprecedented for the whole world, with many unknowns, including for the field of Pediatric Oncology and Dental Surgery. First of all, we highlight the adult or child oncological ill patient – as an emergency patient, therefore, the child with the malignant tumor must be treated urgently. Therefore, the treatment of oncological ill patients was conditionaly devided into 3 groups. Group I – primary patients with a diagnosis of malignant tumor, histologically confirmed, who must undergo treat- ment. Postponing this treatment is more dangerous than coronavirus. The treatment should be conducted under pandemic conditions: at distance, using disinfectants, masks, visiting relatives prohibition. Group II – pediatric patients, who at the beginning of the pandemic were at the treatment stage (chemo- or radiother- apy). If the concrete situation allows, the treatment continues. Hormone injection therapy can be performed at home by the specialized team (doctor and nurse). Group III – consisting of children – patients, who have undergone treatment and currently have no signs of disease, but require monitoring. These patients must be in quarantine. Oncological ill patients are considered to have compromised immunity. In adolescent and children, immunity is rela- tively good if there are no serious diseases such as systemic diseases. The tactics must be personalized, strictly individual. During 2020 we performed 3 types of surgical interventions in pediatric oncology: typical surgeries, enlarged surger- ies, combined surgeries.

Author(s):  
KRISHNA PRASAD MARAM ◽  
Vikram Kudumula ◽  
Dilip Ratti

Primary cardiac tumors are rare in children, usually consist of benign tumors like rhabdomyomas and fibromas that may spontaneously regress. Primary malignant tumors are extremely rare even in adults and very few paediatric cases were reported in literature. Rhabdomyosarcoma is a rare primary malignant tumor in children and most of the reported cases occur in right ventricle, left atrium and right atrium. We report a 15 month old child with primary rhabdomyosarcoma of left ventricle presenting in cardiac tamponade and circulatory failure.


2020 ◽  
pp. 1-3
Author(s):  
Richa Chauhan ◽  
Richa Chauhan ◽  
Gyanendra Singh ◽  
Upendra Prasad Singh

Renal cell carcinoma (RCC) is an uncommon malignant tumor of the kidney, particularly in the Asian population. It is more commonly seen in an elderly male patient with typical complains of haematuria, flank pain and lump. Recently incidental diagnosis of small RCCs has been rising due to increased used of abdominal imaging for other reasons. Spontaneous rupture of a renal mass leading to large perinephric collection and presenting as an acute pain abdomen in an adult male is a rare finding but should be considered as a differential diagnosis. The most common cause of spontaneously ruptured renal mass includes benign tumor as angiomyolipoma followed by malignant tumor like RCC, vascular causes, coagulation defects and infection in other cases. Contrast enhanced CT scan is the most common imaging modality used for diagnosis. Initial resuscitation depending up on the patient’s general condition followed by nephrectomy for malignant tumors and embolization for benign tumors is the treatment of choice.


2019 ◽  
pp. 39-42
Author(s):  
G.Yu. BEREZKINA ◽  
S.L. VOROBYEVA ◽  
E.M. KISLYAKOVA ◽  
A.A. KOREPANOVA

Изучено влияние возраста и живой массы при первом осеменении на воспроизводительные качества коровпервотелок чернопестрой породы в племенных заводах Удмуртской Республики. Исследования проводились в период с 2015 по 2018 гг. Для проведения исследований были сформированы 6 групп животных в зависимости от возраста первого осеменения. В I группу вошли коровы с возрастом первого осеменения до 13 мес, во II от 13,1 до 15 мес, в III от 15,1 до 17, в IV от 17,1 до 19, в V от 19,1 до 21 и в VI группу от 21 мес и старше. При этом живая масса телок в I группе в среднем составила 349,5 кг, во II 370,9, в III 387,7, в IV 400,2, в V 420,7 и в VI группе 440,2 кг. Анализ возраста первого осеменения в племенных хозяйствах республики показал, что средний возраст плодотворного осеменения в 2018 году составил 17,0 мес. с живой массой 394 кг. По результатам экспериментальных исследований нами получено, что лучшие воспроизводительные показатели и молочная продуктивность выявлена у коровпервотелок, которых осеменяли в возрасте 14,6 мес. В данной группе продолжительность сервиспериода составила 127,3 дня, коэффициент воспроизводительной способности 0,90, выход телят на 100 коров составил более 85,3. Удой за 305 дней лактации, у коровпервотелок второй опытной группы составил 6332,3 кг с массовой долей жира 3,65 и белка 3,15 .The influence of age and live weight at the first insemination on reproductive qualities of cowsborn black and white breed in breeding farms of the Udmurt Republic was studied. The studies were conducted between 2015 and 2018. For the research 6 groups of animals were formed depending on the age of the first insemination. Group I included cows with the age of first insemination up to 13 months, in group II from 13.1 to 15 months, in III group from 15.1 to 17 months, in group IV from 17.1 to 19 months, in group V from 19.1 to 21 months and in VI group from 21 months and more. At the same time, the live weight of heifers in group I averaged 349.5 kg, in group II370.9 kg, in group III 387.7 kg, in group IV 400.2 kg, in group V 420.7 kg and in group VI 440.2 kg. The analysis of the age of the first insemination in breeding farms of the Republic showed that the average age of fruitful insemination in 2018 was 17.0 months with a live weight of 394 kg. According to the results of experimental studies, we obtained that the best reproductive performance and milk productivity was revealed in cows, which were inseminated at the age of 14.6 months. In this group, the duration of the service period was 127.3 days, the coefficient of reproductive capacity 0.90, yield of calves per 100 cows. Milk yield for 305 days of lactation, in cows of the second experimental group was 6332.3 kg with a mass fraction of fat 3.65 and protein 3.15.


2021 ◽  
Vol 13 (2) ◽  
pp. 11-17
Author(s):  
R. M. Kabardaev ◽  
E. R. Musaev ◽  
A. K. Valiev ◽  
K. A. Borzov ◽  
S. F. Kuznetsov ◽  
...  

Introduction. Radical surgical resections in the treatment of malignant tumors of the spine have proven effective in improving both overall and disease-free survival of patients. Indications for such interventions are primary malignant tumors of the spine, primary benign tumors with aggressive growth, and solitary metastatic lesions in patients with a favorable oncological prognosis. Due to the anatomical features of the vertebral column, it is very difficult to perform radical resections. An even more difficult task is to perform such interventions for multilevel spinal lesions.The study objective is to evaluate the results of radical surgical treatment for multilevel tumor lesions of the spine.Materials and methods. From 2004 to 2019, in the department of spine surgery of the N.N. Blokhin National Medical Research Center of Oncology treated 36 patients with spinal tumors, who underwent multilevel radical resections. The analysis of this surgical treatment of patients with multilevel neoplastic lesions of the spine was carried out.Results. Performing radical surgical interventions on the spine makes it possible to reduce the frequency of local relapses, improve functional results and overall survival of patients. After performing multilevel resections, complications often occur.


2016 ◽  
Vol 1 (1) ◽  
pp. 27-29 ◽  
Author(s):  
Гизатова ◽  
Natalya Gizatova

The research object is improvement of the productive qualities of heifers of Kazakh white breed by introducing additional to the basic diet of different doses of feed additives BioDarin. Protein-vitamin-mineral supplement BioDarin in its composition contains nutrients, micro- and macroelements, which are the source of energy, stimulate digestive processes, metabolism, growth and improve immunity, positive effect on animal performance. Currently of great practical and scientific importance is the use of the additive BioDarin for the correction of diet feeding. Scientific and economic experiment was carried out on the basis of JSC AIC «Alga+» Tuimazinsk district of the Republic of Bashkortostan. For the experiment there were formed 4 groups of heifers of Kazakh white-headed breed: group I – control; group II heifers in addition to the basic diet received a feed additive in a dose of 0.5 kg per 100 kg of grain mixture, the animals of group III received 1 kg of the feed additive per 100 kg of grain mixture, peers IV groups received 1.5 kg of a grain mixture. It is established that heifers of the III experienced group receiving feed additive BioDarin in the dose of 1.0 kg per 100 kg of grain mixture, had the best body weight, and average day growth.


Author(s):  
I. I. Rosenfeld

Aim. The article discusses the results of a study using a patented method of two-layer laparoscopic repair of large and giant hiatal hernias using a biocarbon implant in comparison with other surgical techniques.Materials and methods. 716 patients were divided into 3 study groups based on the area of the size of the esophageal hernia defect: group I (314 patients) – with small (less than 5 cm2) and medium (5–10 cm2) hiatal hernias, that is, up to 10 cm2, which hernioplasty was performed only by the method of posterior cruraphy; group II (323 patients) – with large hernias 10–20 cm2: subgroup 1 (92 patients) underwent posterior cruraphy, subgroup 2 (231 patients) – alloplasty. Depending on the alloplasty technique, subgroup 2, in turn, was divided: subgroup A (89 people) – hernioplasty with a polypropylene implant and subgroup B (142 people) – hernioplasty with a medical biocarbon construction. Study group III (79 patients) – patients with giant diaphragmatic hernias of more than 20 cm2 using alloplasty: subgroup A (29 people) – hernioplasty with a polypropylene implant and subgroup B (50 patients) – alloplasty with a medical biocarbon construction.Results. When comparing group I with subgroup 1 of group II, the following results were obtained. Statistically significant differences were found in the degrees and types of diaphragmatic hernias. The average age of patients and statistical differences for it were insignificant. When comparing subgroup 1 with subgroup 2 of group II, statistically insignificant differences were found in the degrees and types of hiatal hernias. The difference in the average age of patients was also statistically insignificant. The difference in the average age of patients was also statistically insignificant. When comparing subgroup A with subgroup B of group II, statistically insignificant differences were found among themselves in the degrees and types of hiatal hernias. When comparing subgroup 2 of group II with group III, the difference turned out to be statistically significant in the distribution of patients by types and degrees of diaphragmatic hernias. When comparing subgroup A with subgroup B of group III by degrees and types of hiatal hernias, statistically insignificant differences were revealed.Conclusion. Posterior cruraphia in small and medium diaphragmatic hernias had significant statistical differences in types and degrees compared to that in large hernias, as well as in the average area of the hernial defect. Posterior cruraphia with hernioplasty in large hiatal hernias did not differ statistically significantly according to any of the criteria. Plastic surgery with a polypropylene implant with alloplasty of a biocarbon implant for large hernias did not differ significantly according to any of the criteria. Hernioplasty for large hiatal hernias, when compared with giant hernias, differed significantly only in the degree and type, as well as in the area of the hernial defect. «Onlay» plastic surgery with a polypropylene implant with alloplasty of biocarbon structures for giant hernias did not differ significantly according to any of the criteria, except for gender distribution, which did not have significant fundamental significance, which made it possible to make a more correct comparison of the results of surgical interventions in these research subgroups.


2016 ◽  
Vol 1 (1) ◽  
pp. 23-26
Author(s):  
Долженкова ◽  
Galina Dolzhenkova ◽  
Тагиров ◽  
Khamit Tagirov ◽  
Гизатова ◽  
...  

The research objective is improvement of the productive qualities of Kazakh white breed heifers by introducing in addition to the basic diet of different doses of feed additives BioDarin. Currently raising meats-term productivity of livestock through a full feeding is promising direction. One way of addressing this issue is the use in the diet of animals. One of the promising supplements is BioDarin. Scientific and economic experiment was carried out on the basis of JSC AIC «Alga+» Tuimazinsk district of the Republic of Bashkortostan. For the experiment there were formed 4 groups of heifers of Kazakh white breed: group I – control; group II heifers in addition to the basic diet received a feed additive in a dose of 0.5 kg per 100 kg of grain mixture, the animals of group III received 1 kg of the feed additive per 100 kg of grain mixture, peers IV groups received 1.5 kg of a grain mixture. Among the studied groups, heifers of the III experienced group receiving feed additive at a dose of 1.0 kg per 100 kg of grain mixture, had better hematological indices. In the course of the research established that the highest levels of productivity and better metabolism differed heifers, which were included in the diet a food additive BioDarin.


1982 ◽  
Vol 68 (2) ◽  
pp. 133-136
Author(s):  
G. Pastore ◽  
L. Cordero Di Montezemolo ◽  
A. Brach Del Prever ◽  
G. Bartolozzi ◽  
M. Carli ◽  
...  

Thirty-four infants under 1 year of age with Wilms’ tumor were diagnosed and treated in 14 Italian pediatric oncology units during 1970-79. The 3-year survival rates decreased with higher group unilateral tumors: 95% in group I Wilms’ tumor, 75% in group II and 20% in group III. The survival rates for children with group I and II Wilms’ tumor were similar for those who were treated with surgery and chemotherapy and those who also received postoperative radiotherapy. During 1975-79 fewer patients with group I Wilms’ tumor received radiotherapy (1 of 11) than during 1970-74 (4 of 6, p < 0.05). All these children are alive at this writing.


2019 ◽  
Vol 1 (Supplement_2) ◽  
pp. ii26-ii26
Author(s):  
Shinichi Okonogi ◽  
Shuuhei Kubota ◽  
Yuuki Sakaeyama ◽  
Keita Ueda ◽  
Masaaki Nemoto ◽  
...  

Abstract INTRODUCTION The frequency of intraorbital tumors is small as 0.9% of all brain tumors, but its pathological type is diverse. Among them, the diagnosis of whether particularly malignant tumor scan clinically, is extremely important. Nuclear medical testing is essential for non-invasive differential diagnosis in brain tumors. SPECT, good malignancy differentiation, evaluation of malignancy, usefulness such as differentiation of non-tumorous lesions have been reported many. However, there are few reports that SPECT was useful in preoperative differential diagnosis of orbital tumors. Since 123IMP-SPECT was useful in preoperative differential diagnosis of intraorbital tumors, we report some literature considerations. METHOD Among the 27 cases of intraorbital tumors that were operated on in our clinic between August 2005 and August 2016, 14 cases of SPECT prior to surgery were examined for the usefulness of preoperative differential diagnosis. Breakdown of cases, as the malignant tumor, two cases of malignant lymphoma, MALT lymphoma 2 cases, adenoid cystic carcinoma 1 case, in one case plasma cytoma, as a benign tumor, false tumors 4 cases, three hemangioma cases, neurocytoma 1 case it was. RESULTS In IMP early image, accumulation of clear IMP was observed in all six cases of malignant tumors. In benign tumors, there is no accumulation in hemangioma and neurosheath, there is a strong accumulation in one of the four cases in false tumors, it was observed mild accumulation in the remaining two cases. Tumor to normal ratio of IMP early image was an average of 2.39 in six malignant tumors and 1.52 in 8 benign tumors. CONCLUSION This time, we examined the usefulness of 123IMP-SPECT in preoperative differential diagnosis of intraorbital tumors. The T/N ratio of intraorbital malignant tumors is higher than benign tumors, and it was thought to help to evaluate preoperative malignancy of intraorbital tumors.


Author(s):  
А.Р. ФАРХУТДИНОВА ◽  
М.Т. САБИТОВ

In a scientific and economic experiment lasting 90 days on 4 groups of black-and-white calves, formed by the method of analogs, the effect of a complex mineral-vitamin feed supplement (CMVFS ) on the nutrient digestibility of feed in the Republic of Bashkortostan was studied. Animals of the control group received the basic diet (BD) and mineral feeds (chalk, salt, premix); I, II and III experimental groups — BD + CMVFS according to recipe No. 1, No. 2 and No. 3 respectively. A distinctive feature of the recipes is the ratio of natural zeolite and sapropel in 1 kg of the supplement. It was found that the content of calcium, phosphorus, magnesium, sulfur, manganese, copper, zinc and cobalt in the green mass, as well as in the feed harvested from it, does not meet the needs of young animals. Significantly high digestibility of dry and organic matter relative to the control was observed in animals of group III by 3.84% (R<0.05) and 2.78% (R<0.05); crude protein — by 3.21 and 3.96% — in young animals of groups II and III (R<0.05); crude fat — by 2.83% (R<0.05) in group I, by 4.01% (R<0.05) in group II and by 5.05% (P<0.01) in group III; nitrogen-free extractive substances — by 3.24% (R<0.05) in II and by 3.67% (R<0.05) in III experimental groups. The balance of nitrogen and minerals in all experimental groups was positive. The digested and deposited nitrogen in the body corresponds to the obtained average daily live weight gain of calves. In order to balance the diets of calves in terms of macro- and microelements, we recommend vitamins to introduce CMVFS according to the recipe No. 3 into the mixture of grains at the rate of 35 g per 1 head per day.


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