A CASE OF PRIMARY HYPERPARATHYROIDISM

Vestnik ◽  
2021 ◽  
pp. 195-197
Author(s):  
М.Е. Рамазанов ◽  
Р.Б. Базарбекова ◽  
А.К. Досанова ◽  
Ж.С. Шерияздан ◽  
У.З. Апбасова ◽  
...  
Keyword(s):  
Primary Hyperparathyroidism ◽  
Endocrine Diseases ◽  
Hypercalcemic Crisis ◽  
Benign Adenoma ◽  
Menopausal Women ◽  
High Incidence ◽  
The Common ◽  
The Given ◽  
Over 40 Years ◽  
Over Time

Первичный гиперпаратиреоз - одно из распространенных, но трудно диагностируемых в реальной клинической практике эндокринных заболеваний у взрослых. Актуальность данной публикации определяется высокой частотой заболевания у лиц старше 40 лет. Риск его возникновения у людей 40-50 лет достигает 2%. Имеются все основания считать, что данный показатель с течением времени будет увеличиваться, поскольку согласно прогнозам отдела народонаселения Организации Объединённых Наций от 2001г. удельный вес пожилых людей к 2050г. в мире достигнет 21% в сравнении с 10% в 2000г. Особенно подвержены первичному гиперпаратиреозу женщины менопаузального возраста, у которых заболевание встречается с частотой 1:500. В большинстве случаев первичный гиперпаратиреоз возникает вследствие солитарной доброкачественной аденомы паращитовидных желез. В данной статье представлен случай аденомы паращитовидной железы с развитием гиперкальциемического криза у женщины в возрасте 49 лет, выбор дальнейшей тактики ведения - консервативное или оперативное лечение, а также рекомендации по наблюдению в динамике. Приведенный случай будет интересен специалистам как терапевтического, так и хирургического профиля. Primary hyperparathyroidism is one of the common but difficult to diagnose endocrine diseases in adults in real clinical practice. The relevance of this publication is determined by the high incidence of the disease in persons over 40 years of age. The risk of its occurrence in people 40-50 years old reaches 2%. There is every reason to believe that this figure will increase over time, since according to the projections of the UN Population Division for 2001, the proportion of elderly people in the world will reach 21% by 2050, compared with 10% in 2000. Menopausal women are especially susceptible to primary hyperparathyroidism which the disease occurs with a frequency of 1: 500. In most cases, primary hyperparathyroidism occurs due to solitary benign adenoma of the parathyroid glands. This article presents a case of parathyroid adenoma with the development of a hypercalcemic crisis in a woman aged 49 years, the choice of further management tactics - conservative or surgical treatment, as well as recommendations for monitoring over time. The given case will be of interest to specialists of both therapeutic and surgical profile.

scholarly journals Primary hyperparathyroidism: case report

2021 ◽  
Vol 14 (2) ◽  
pp. 21-24
Author(s):  
Leila M. Farkhutdinova ◽  
Salam Yu. Mohammad ◽  
Ildar M. Yamaev ◽  
Bulat I. Abdulguzhin
Keyword(s):  
Primary Hyperparathyroidism ◽  
Clinical Case ◽  
Severe Form ◽  
Laboratory Studies ◽  
Mineral Density ◽  
Severe Osteoporosis ◽  
Multiple Fractures ◽  
Endocrine Diseases ◽  
The Russian Federation ◽  
The Common

Primary hyperparathyroidism is one of the common endocrine diseases, which is an actual medical and social problem. Bone disorders are the most common manifestations of primary hyperparathyroidism and are characterized by increased bone metabolism with a progressive decrease in mineral density and a high risk of fractures. In the Russian Federation, most cases are manifest forms of the disease (70%), which is mainly due to the low level of diagnosis, including due to the lack of awareness of doctors. At the same time, timely detection of the disease is based on relatively accessible laboratory studies, characterized by elevated levels of calcium and parathyroid hormone in the blood, and ultrasound and scintigraphy in most cases provide visualization of the paraadenoma. A clinical case of a severe form of primary hyperparathyroidism, the late diagnosis of which caused the development of severe osteoporosis with multiple fractures, is considered. The presented case indicates that an important role in the timely detection of the disease belongs to the analysis of the clinical picture.

Articulatory Generalization in Two Word-Medial, Ambisyllabic Contexts

1988 ◽  
Vol 19 (3) ◽  
pp. 251-258 ◽  
Author(s):  
Virginia I. Wolfe ◽  
Suzanne D. Blocker ◽  
Norma J. Prater
Keyword(s):  
Common View ◽  
Perceptual Salience ◽  
The Common ◽  
Unitary Concept ◽  
Over Time

Articulatory generalization of velar cognates /k/, /g/ in two phonologically disordered children was studied over time as a function of sequential word-morpheme position training. Although patterns of contextual acquisition differed, correct responses to the word-medial, inflected context (e.g., "picking," "hugging") occurred earlier and exceeded those to the word-medial, noninflected context (e.g., "bacon," "wagon"). This finding indicates that the common view of the word-medial position as a unitary concept is an oversimplification. Possible explanations for superior generalization to the word-medial, inflected position are discussed in terms of coarticulation, perceptual salience, and the representational integrity of the word.

THE EU SUGAR MARKET PROFILE AND ITS MAIN DRIVERS

2015 ◽  
Author(s):  
Lubos SMUTKA ◽  
Irena BENEŠOVÁ ◽  
Patrik ROVNÝ ◽  
Renata MATYSIK-PEJAS
Keyword(s):  
Market Failure ◽  
Current System ◽  
Quota System ◽  
Considerable Debate ◽  
Sugar Market ◽  
The Common ◽  
The One ◽  
Production Capacities ◽  
The Given ◽  
The Eu

Sugar is one of the most important elements in human nutrition. The Common Market Organisation for sugar has been a subject of considerable debate since its establishment in 1968. The European agricultural market has been criticized for its heavy regulations and subsidization. The sugar market is one of the most regulated ones; however, this will change radically in 2017 when the current system of production quotas will end. The current EU sugar market changed is structure during the last several decades. The significant number of companies left the market and EU internal sugar market became more concentrated. The aim of this paper is presentation characteristics of sugar market with respect to the supposed market failure – reduction in competition. The analysis also identifies the main drivers and determinants of the EU especially quota sugar market. In relation to paper’s aim the following results are important. The present conditions of the European sugar market have led to market failure when nearly 75 % (10 million tonnes) of the quota is controlled by five multinational companies only. These multinational alliances (especially German and French one) are also taking control over the production capacities of their subsidiaries. In most countries, this causes serious problems as the given quota is controlled by one or two producers only. This is a significant indicator of market imperfection. The quota system cannot overcome the problem of production quotas on the one hand and the demand on the other; furthermore, it also leads to economic inefficiency. The current EU sugar market is under the control of only Sudzucker, Nordzucker, Pfeifer and Langen, Tereos and ABF.

The Still Life of Objects – Heidegger, Schapiro, and Derrida reconsidered

2015 ◽  
Vol 60 (1) ◽  
pp. 81-102
Author(s):  
KErstin Thomas
Keyword(s):  
Still Life ◽  
Work Of Art ◽  
Concrete Material ◽  
Vincent Van Gogh ◽  
Starting Point ◽  
Specific Object ◽  
Truth Claims ◽  
The Common ◽  
Critical Intervention ◽  
The Given

Kerstin Thomas revaluates the famous dispute between Martin Heidegger, Meyer Schapiro, and Jacques Derrida, concerning a painting of shoes by Vincent Van Gogh. The starting point for this dispute was the description and analysis of things and artworks developed in his essay, “The Origin of the Work of Art”. In discussing Heidegger’s account, the art historian Meyer Schapiro’s main point of critique concerned Heidegger’s claim that the artwork reveals the truth of equipment in depicting shoes of a peasant woman and thereby showing her world. Schapiro sees a striking paradox in Heidegger’s claim for truth, based on a specific object in a specific artwork while at the same time following a rather metaphysical idea of the artwork. Kerstin Thomas proposes an interpretation, which exceeds the common confrontation of philosophy versus art history by focussing on the respective notion of facticity at stake in the theoretical accounts of both thinkers. Schapiro accuses Heidegger of a lack of concreteness, which he sees as the basis for every truth claim on objects. Thomas understands Schapiro’s objections as motivated by this demand for a facticity, which not only includes the work of art, but also investigator in his concrete historical perspective. Truth claims under such conditions of facticity are always relative to historical knowledge, and open to critical intervention and therefore necessarily contingent. Following Thomas, Schapiro’s critique shows that despite his intention of giving the work of art back its autonomy, Heidegger could be accused of achieving quite the opposite: through the abstraction of the concrete, the factual, and the given to the type, he actually sets the self and the realm of knowledge of the creator as absolute and not the object of his knowledge. Instead, she argues for a revaluation of Schapiro’s position with recognition of the arbitrariness of the artwork, by introducing the notion of factuality as formulated by Quentin Meillassoux. Understood as exchange between artist and object in its concrete material quality as well as with the beholder, the truth of painting could only be shown as radically contingent. Thomas argues that the critical intervention of Derrida who discusses both positions anew is exactly motivated by a recognition of the contingent character of object, artwork and interpretation. His deconstructive analysis can be understood as recognition of the dynamic character of things and hence this could be shown with Meillassoux to be exactly its character of facticity – or factuality.

Use of Phosphatidylcholine in the Treatment of Localized Fat Deposits. Results and expectations

2017 ◽  
Vol 68 (7) ◽  
pp. 1438-1441 ◽  
Author(s):  
Sorin Berbece ◽  
Dan Iliescu ◽  
Valeriu Ardeleanu ◽  
Alexandru Nicolau ◽  
Radu Cristian Jecan
Keyword(s):  
World Health Organisation ◽  
Normal Weight ◽  
World Health ◽  
Basic Substance ◽  
Physical Exercises ◽  
Fat Deposits ◽  
The World ◽  
The Common ◽  
Global Health Problem ◽  
Over Time

Obesity represents a global health problem. According to the latest studies released by the World Health Organisation (WHO), 1.7 billion currently in excess of normal weight individuals, of which approx. 75% are overweight (body mass index - BMI 25 to 30). The common form of excess adipose tissue manifestation in overweight individuals is localized fat deposits with high (abdominal) or low (buttocks and thighs) disposition. Although the overweight can be corrected relatively easy by changing behavioral habits or food, a constant physical exercises program or following a diet food are not accessible to all through the efforts of will, financial and time involved. Several methods have been studied and tested over time to eliminate more or less invasive fat deposits with varying efficacy and adverse effects. Chemical lipolysis using phosphatidylcholine as the basic substance was initially used in hypercholesterolemia and its complications and was rapidly adopted in mesotherapy techniques for the treatment of fat deposits. This study reveals the results obtained using Dermastabilon on a sample of 16 patients, the time allocated to treatment and discomfort being minimal, and rapid and notable results. There were no side effects.

scholarly journals Acute symptoms of mild to moderate COVID-19 are highly heterogeneous across individuals and over time

2021 ◽  
Author(s):  
Thomas L Rodebaugh ◽  
Madelyn R Frumkin ◽  
Angela M Reiersen ◽  
Eric J Lenze ◽  
Michael S Avidan ◽  
...  
Keyword(s):  
Temporal Dynamics ◽  
Survey Methods ◽  
Clinical Care ◽  
Clinical Deterioration ◽  
Symptom Profiles ◽  
Fluctuating Course ◽  
The Common ◽  
Symptom Changes ◽  
Over Time

Abstract Background The symptoms of COVID-19 appear to be heterogenous, and the typical course of these symptoms is unknown. Our objectives were to characterize the common trajectories of COVID-19 symptoms and assess how symptom course predicts other symptom changes as well as clinical deterioration. Methods 162 participants with acute COVID-19 responded to surveys up to 31 times for up to 17 days. Several statistical methods were used to characterize the temporal dynamics of these symptoms. Because nine participants showed clinical deterioration, we explored whether these participants showed any differences in symptom profiles. Results Trajectories varied greatly between individuals, with many having persistently severe symptoms or developing new symptoms several days after being diagnosed. A typical trajectory was for a symptom to improve at a decremental rate, with most symptoms still persisting to some degree at the end of the reporting period. The pattern of symptoms over time suggested a fluctuating course for many patients. Participants who showed clinical deterioration were more likely to present with higher reports of severity of cough and diarrhea. Conclusion The course of symptoms during the initial weeks of COVID-19 is highly heterogeneous and is neither predictable nor easily characterized using typical survey methods. This has implications for clinical care and early-treatment clinical trials. Additional research is needed to determine whether the decelerating improvement pattern seen in our data is related to the phenomenon of patients reporting long-term symptoms, and whether higher symptoms of diarrhea in early illness presages deterioration.

scholarly journals On the Difficulty of Budget Allocation in Claims Problems with Indivisible Items and Prices

2021 ◽  
Author(s):  
Teresa Estañ ◽  
Natividad Llorca ◽  
Ricardo Martínez ◽  
Joaquín Sánchez-Soriano
Keyword(s):  
Budget Allocation ◽  
Pareto Efficiency ◽  
Claims Problems ◽  
The Common ◽  
The Given

AbstractIn this paper we study the class of claims problems where the amount to be divided is perfectly divisible and claims are made on indivisible units of several items. Each item has a price, and the available amount falls short to be able to cover all the claims at the given prices. We propose several properties that may be of interest in this particular framework. These properties represent the common principles of fairness, efficiency, and non-manipulability by merging or splitting. Efficiency is our focal principle, which is formalized by means of two axioms: non-wastefulness and Pareto efficiency. We show that some combinations of the properties we consider are compatible, others are not.

scholarly journals Business Co-operatives in Australia: “Unlikely Soil for a Co-operative Movement”

2021 ◽  
pp. 1-25
Author(s):  
Greg Patmore ◽  
Nikola Balnave ◽  
Olivera Marjanovic
Keyword(s):  
Business Model ◽  
Common Good ◽  
Business Owners ◽  
The Self ◽  
Small Business Owners ◽  
Large Database ◽  
Average Life ◽  
Direct Competition ◽  
The Common ◽  
Over Time

While co-operatives are traditionally associated with workers, consumers, and farmers, the business model, with its emphasis on democracy and community, has also been adopted by small business owners, the self-employed, and professionals. These business co-operatives are distinct phenomenon, because they primarily consist of independent organizational entities that are not co-operatives and are generally in direct competition with one another. They are unique in that they bring together separate organizations that seek to combat market threats while adopting a philosophy based on co-operative principles. This article begins with an overview of the Australian co-operative landscape. It then defines the concept of business co-operatives and then draws upon the Visual Atlas of Australian Co-operatives History Project, which has developed a large database of Australian co-operatives over time and space, to examine the development of business co-operatives in Australia. It looks at where business co-operatives formed in the economy, the motivation underlying their formation, their average life spans, and their relationships with the broader co-operative movement. The article highlights the value of business co-operatives in introducing the values of participatory democracy and working for the common good into unanticipated markets and reinforcing the co-operative movement.

scholarly journals Does the Arc of Science Bend Towards Impact? Four Decades of Empirical Research Published in JADD Since the DSM-III

2021 ◽  
Author(s):  
Peter Doehring
Keyword(s):  
Empirical Research ◽  
Research Funding ◽  
Basic Research ◽  
Intervention Research ◽  
Community Based ◽  
Community Impact ◽  
Population Impact ◽  
Community Based Programs ◽  
Over 40 Years ◽  
Over Time

AbstractThe present study explored the shift from understanding to intervention to population impact in the empirical research published in this journal at five points of time over 40 years since the release of DSM-III. Two-thirds of the more than 600 original studies identified involved basic research, a pattern that is consistent with previous analyses of research funding allocations and that did not change over time. One of every eight studies involved intervention research, which occurred in community-based programs only about one-quarter of the time. These gaps in intervention research and community impact did not improve over time. The findings underscore the need to broaden the training and experience of researchers, and to re-consider priorities for research funding and publication.

Common Heritage of Mankind as a Limit to Exploitation of the Global Commons

2019 ◽  
Vol 30 (2) ◽  
pp. 635-663
Author(s):  
Karin Mickelson
Keyword(s):  
Global Commons ◽  
Common Heritage ◽  
Economic Exploitation ◽  
Common Heritage Of Mankind ◽  
The Commons ◽  
The Common ◽  
Environmental Limits ◽  
Over Time

Abstract This contribution to the symposium on the economic exploitation of the commons focuses on the question of whether and to what extent the principle of the common heritage of mankind (CHM) imposes environmental limits on economic exploitation of the global commons. Focusing on the need to go beyond a unidimensional assessment of the principle, it considers how CHM was originally envisaged, the form it took in the deep seabed regime, in particular, how its role in that regime has developed over time and how it has been utilized as a basis for advocacy. It concludes with an assessment of CHM’s limitations and strategic advantages.

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