scholarly journals BENEFICIAL EFFECTS OF TREATMENT WITH TOCILIZUMAB IN MODERATE TO CRITICALLY ILL COVID-19 PATIENTS

2021 ◽  
Vol 2021 (1) ◽  
Author(s):  
MA Rana ◽  
MS Hashmi ◽  
R Pervaiz ◽  
A Qayyum ◽  
MMU Saif ◽  
...  
Keyword(s):  
Critically Ill ◽  
Serum Ferritin ◽  
The Body ◽  
Rank Test ◽  
P Value ◽  
Beneficial Effects ◽  
Before And After ◽  
Interleukin 6 Receptor ◽  
Clinical Benefits ◽  
Signed Rank Test

Introduction: COVID-19 virus initiates an inflammatory response in the body involving many cytokines. Interluukin-6 (IL-6) is one of them, elevated levels of which found to be directly related to morbidity and mortality of infected patients. The aim of the current study was to evaluate the clinical benefits of Tocilizumab, a monoclonal antibody against interleukin-6 receptor, as a therapeutic agent for the treatment of Coronavirus disease 2019. Methods: The current retrospective study was conducted at Bahria Town International hospital from rom May 1st to 5th July 2020. Total of one twenty (n=120) moderate to severely ill patients (94 males and 26 females), infected with SARS-CoV-2 virus, were included to assess the effect of TOCILIZUMAB in improvement of PF ratio and other biochemical variables of prognostic importance, including CRP, serum ferritin levels, D-dimers and LDH. These parameters were compared before and after the ten days of treatment with tocilizumab. Demographic, laboratory and clinical finding were recorded for the feather analyses.  Statistical analysis was performed by using software SPSS version 21.0. The Wilcoxon signed‐rank test used to compare parameters whenever appropriate. A P‐value of less than .05 was considered statistically significant. Results: The results of our study showed statistically significant improvement in PF ratio and decrease in CRP levels. Other parameters such as D-Dimer, Serum ferritin levels and LDH showed no change before and after treatment with tocilizumab. Conclusion: In summary, TOCILIZUMAB improved the PF and CRP ratio in COVID-19 patients, but other markers did not improve in response to TOCILIZUMAB in critically ill COVID-19 patients.

Effect Of Pregnancy Exercise On Third Trimester Primigravida Anxiety In Dealing With Childbirth

2021 ◽  
pp. 76-83
Author(s):  
Ismi Puji Astuti
Keyword(s):  
Treatment Group ◽  
Sampling Technique ◽  
The Body ◽  
Rank Test ◽  
Control Group ◽  
P Value ◽  
Research Subjects ◽  
Third Trimester ◽  
Quasi Experimental ◽  
Signed Rank Test

Background: The first labor anxiety is an unpleasant psychological condition due to physiological changes that cause psychological instability. The condition of excessive anxiety, worry, fear without cause, and stress, causes the muscles of the body to tense up, especially the muscles in the birth path to become stiff and hard, making it difficult to expand. This study analyzed the effect of pregnancy exercise on third trimester primigravida anxiety in dealing with childbirth. Methods: Quasi experimental design with nonrandomized pretest-postest control group. The sampling technique used was purposive sampling with 34 research subjects. 17 people for the treatment group were given pregnancy exercise 8 times, and 17 people for the control group were given health education about preparation for childbirth. Results: The results of data analysis using the Wilcoxon signed rank test showed that the average reduction in the treatment group was 8.00 and the control group was 3.00. The effect of pregnancy exercise on third trimester primigravida anxiety in the treatment group with a p-value (0.000) <(0.05), while the control group with a p-value (0.180)> (0.05). Conclusion: There is an effect of pregnancy exercise on third trimester primigravida anxiety in dealing with childbirth in the Wuryantoro Health Center work area. 

EFEKTIVITAS PEMBERIAN INFUSED WATER KURMA TERHADAP PENINGKATAN KADAR HEMOGLOBIN REMAJA PUTRI KEBIDANAN POLTEKKES MEDAN TAHUN 2020

2021 ◽  
Vol 2 (1) ◽  
pp. 64-69
Author(s):  
HIJRA HIDAYANA ◽  
Suswati Suswati
Keyword(s):  
Red Blood Cells ◽  
Adolescent Girls ◽  
Blood Cells ◽  
The Body ◽  
Rank Test ◽  
Plain Water ◽  
P Value ◽  
Signed Rank ◽  
Wilcoxon Signed Rank Test ◽  
Signed Rank Test

Hemoglobin is the red pigment-protein contained in red blood cells. The function of hemoglobin is to transport oxygen from the lungs and in the bloodstream to be carried to the tissues. Hemoglobin can increase by increasing the intake of iron in the body. One way to increase hemoglobin can be done by giving method Infused Water Dates. Infused water is a drink consisting of plain water with fresh fruit added and soaking or settling together for a certain time. The making of infused water is carried out by soaking for a period of 0 to 12 hours, so that the infused water becomes a liquid medium that carries more nutrients than ordinary water and will be more easily absorbed by cells and distributed throughout the body (Sidauruk, 2018 ). In several studies, it is stated that dates can increase hemoglobin levels in the blood. Where dates contain iron, vitamin A, vitamin C, protein to form red blood cells. With the method, Infused Water the date palm water becomes alkaline so that it can accelerate the absorption process in the body. The purpose of this study was to determine the effectiveness of dates infused water provision to increase hemoglobin levels of midwifery adolescent girls at Medan Health Polytechnic in 2020. This research was quasi-experimental study using the One Group Pretest-Posttest Without Control Design approach. The sample in this study were 20 respondents of midwifery adolescent girls from Medan Health Polytechnic, using the technique of purposive sampling. The statistical test used wa the Wilcoxon Signed Rank Test because the data was not normal. The results of the Wilcoxon Signed Rank Test obtained the value of P-Value = 0.001. So it can be concluded that the date infused water  is effective in increasing hemoglobin levels of midwifery adolescent girls at Medan Health Polytechnic in 2020.   Keywords: Dates Infused Water, Increased Hemoglobin Levels, Girls Adolescent

scholarly journals Three Acupoints of Acupressure Improve the Anxiety Level in Cancer Patients based on Types of Cancer Therapy

2019 ◽  
Vol 13 (4) ◽  
pp. 110
Author(s):  
Yesiana Dwi Wahyu Werdani
Keyword(s):  
Cancer Therapy ◽  
Cancer Patients ◽  
Anxiety Level ◽  
The Body ◽  
Rank Test ◽  
P Value ◽  
Chemotherapy Group ◽  
Post Test ◽  
Physical Disorders ◽  
Signed Rank Test

Background: Cancer and its therapeutic management trigger the multiorgans physical disorders, that can cause the patient to worry and become anxious about the condition. Three acupoints of acupressure therapy stimulates relaxation of the body and can reduce anxiety. The purpose was to determine the influence of three acupoints of acupressure therapy to improve the anxiety level in cancer patients based on types of cancer therapy.Methods: This was an interventional study using pre-experiment pre-test post-test design. Samples were 30 cancer patients living at the Indonesian Cancer Foundation East Java Branch Surabaya Indonesia, taken by purposive technique sampling based on inclusion criteria. The instrument was Beck Anxiety Inventory that it was valid and reliable based on the test. Ethical feasibility tests has been carried out. Acupressure therapy is given on acupoint St36, Li4 and Li11. It conducted 2 times per week for 4 weeks. Wilcoxon Signed Rank Test was applied to analyze this result with p < 0.05.Results: There was a significant effect of acupressure for improving anxiety levels in both groups with p value in the chemotherapy group 0.001 and in the chemoradiotherapy group 0.002. But a greater influence occurred in the chemotherapy group compared to chemoradiotherapy group.Conclusions: Acupressure therapy in three acupoints can stimulate relaxation condition, it can decrease the anxiety level for cancer patients with all types of cancer therapy.

scholarly journals Group Education Model Improving The Knowledge of School Age Children in Protecting of Sexual Violence

2019 ◽  
Vol 3 (4) ◽  
pp. 204
Author(s):  
I Ketut Labir ◽  
Ni Luh Kompyang Sulisnadewi ◽  
I Nyoman Ribek
Keyword(s):  
Sexual Violence ◽  
Sampling Technique ◽  
School Age Children ◽  
Rank Test ◽  
Average Score ◽  
P Value ◽  
School Age ◽  
Significance Level ◽  
Before And After ◽  
Signed Rank Test

Cases of sexual violence and abuse in Indonesia are increasingly common. Not only in adults, children are now victims. Some cases of victims or perpetrators involve underage children. Many parents feel taboo to talk about early childhood education with children. This causes children not to get information that is supposed to protect themselves from sexual violence. Need to do various efforts to provide education to children about knowledge to protect themselves from sexual violence. The purpose of this study was to determine the effect of sexual violence education on children on efforts to protect from sexual violence. This study uses pre-experimental design with approach pretest-posttest design. The number of samples is 195 children taken by purposive sampling technique. Analyze data using  different Wilcoxon Signed Rank test with 95% significance level, p ≤ (0.05). The results showed that the average age of the respondents was 10.2 years and most of the men were 52.8%. Before giving education, the average score of respondents' knowledge about efforts to protect themselves from sexual violence was 6.7 and increased to 7.79 after giving education. There is a difference in knowledge about efforts to protect themselves from sexual violence before and after being given education (p value ≤ 0.001; <α = 0.05). It is recommended that the provision of information about sexual violence be given regularly by teachers and parents.Keywords: Education - Elementary School Age Knowledge - Efforts to Protect Themselves from Sexual Violence

scholarly journals Aromaterapi Lavender dapat Menurunkan Intensitas Nyeri Perineum pada Ibu Post Partum

2017 ◽  
Vol 4 (3) ◽  
pp. 123
Author(s):  
Wiwin Widayani
Keyword(s):  
Post Partum ◽  
Sampling Technique ◽  
Complementary Therapy ◽  
Perineal Pain ◽  
Rank Test ◽  
P Value ◽  
Relieve Pain ◽  
Signed Rank ◽  
Before And After ◽  
Signed Rank Test

<p><em>Perineal</em><em>s pain affects  woman ability to mobilize so that it can cause complications such as post-partum haemoragik</em><em>. T</em><em>rauma to the perineum also cause discomfort and </em><em>dyspareunia</em><em>, therefore, perineal pain management is important. Currently the handling used to relieve pain is complementary therapy aromatherapy with essential oils of lavender, because lavender has the properties of anticonvulsant, antidepressant, anxiolytic, and </em><em>also</em><em> soothing. Aromatherapy stimulates the hypothalamus to secrete chemical mediators that serve as pain relievers and give rise to feelings of happiness. The purpose of this study was to determine the effect of lavender aromatherapy </em><em>to the</em><em> </em><em>perineal pain</em><em> </em><em>intensity in post partum</em><em> women.</em><em> </em><em>This study is a quasy experiment pre and post non random control </em><em>in </em><em>postpartum </em><em>women at</em><em> Bidan Praktik Mandiri in Bandung. Sampling this study using consecutive sampling technique. </em><em>The d</em><em>ata taken using the instrument in the adaptation of a Visual Analog Scale (VAS) </em><em>and </em><em>analy</em><em>zed by using</em><em> the</em><em> wilcoxon signed rank test</em><em>. The result is</em><em> there was a decrease in pain intensity before and after the administration of inhaled lavender aromatherapy</em><em> (</em><em>Z=-3.77</em><em>)</em><em> with p-value 0.001.</em><em> Lavender aromatherapy can be a complementary alternative therap</em><em>y</em><em> to reduce pain in postpartum </em><em>women</em><em> but more research </em><em>necessary </em><em>is needed with </em><em>more </em><em>respondents.</em><strong></strong></p>

scholarly journals Pengaruh Pelatihan terhadap Peningkatan Pengetahuan Kader Posyandu tentang Deteksi Dini TBC Anak di Kelurahan Tanjung Mas Semarang

2021 ◽  
Vol 4 (3) ◽  
pp. 222
Author(s):  
Eti Rimawati ◽  
Sri Handayani ◽  
Catur Yuantari
Keyword(s):  
Early Detection ◽  
Junior High School ◽  
Rank Test ◽  
P Value ◽  
Test Analysis ◽  
Signed Rank ◽  
Before And After ◽  
Signed Rank Test ◽  
The Difference ◽  
Tuberculosis In Children

Introduction: Symptoms of tuberculosis in children that are not specific require early detection efforts. One of the efforts to carry out early detection is to monitor children's growth and development in posyandu activities. Posyandu cadres have an important role in this. The purpose of this training activity is to increase the knowledge of posyandu cadres in early detection of tuberculosis in children. Method: The target of the training was 21 posyandu cadres who were selected by purposive sampling. Training activities as a form of community service are carried out with the stages of giving a pretest, presentation of material and case and posttest questions. The Wilcoxon Signed Rank Test analysis is used to determine differences in knowledge before and after training.Result Recommendation: All cadres were female, with the lowest education was junior high school (9.8%), the youngest was 38 years old and the oldest was 65 years old. The results of the difference test showed that there was a difference between before and after training (p value 0.0006), indicating that the training method was effective in increasing the knowledge of the cadres

scholarly journals PENAMBAHAN LATIHAN CORE STABILITY PADA PROGRAM PELATIHAN ATLET DAYUNG UNTUK PENINGKATAN KECEPATAN MENDAYUNG

2017 ◽  
Author(s):  
Dyno Aryo Christanto ◽  
N. Adiputra ◽  
S. Indra Lesmana ◽  
Dw P. Sutjana ◽  
Made Muliarta ◽  
...  
Keyword(s):  
Training Program ◽  
Core Stability ◽  
Rank Test ◽  
P Value ◽  
Signed Rank ◽  
Wilcoxon Signed Rank Test ◽  
Before And After ◽  
Post Test ◽  
Signed Rank Test ◽  
The Difference

Introduction: Generally, core stability exercise as a training program is needed in almost kind of sport including paddle, analysis of movement in any kind of paddle sport such as kayak, canoe, or even rowing have been showed that the activity of core stability muscles are really needed. Purpose: purpose of this research is to know the effectivity of core stability exercise replenishment to increase sculling speed in paddle training program. Methods: This research is experimental with treatment by subject design project, involving 15 paddle athletes which divided into two groups and consists of II periods which are, Period I and Period II. In the 1st period, the athletes were given extra core stability exercise along with their normal paddling routine mean while in the 2nd period, the athletes only doing their normal paddling routine. Each period do the trial in 6 weeks, so this reseach took 12 weeks. In 1st period, the subjects were given extra core stability training 3 times a week along with their normal paddling routine where as subjects in period II only do their normal paddling routine. Results: The used of parametric paired t test is to know the difference of sculling speed before and after the trials were given. To period I pre test value is 3.80 ± 0.26 meters/second while the post test value is 4.06 ± 0.41 meters/second and the value 0.001 (p<0.05)mean while the 2nd period use Wilcoxon signed rank test to know the difference of sculling speed between before and after the trial were given resulting pre test value 3.80 ± 0.22 meters/second and post test value 3.91 ± 0.27 meters/second while the p value is 0.004 (p<0.05). After 12 weeks of sculling speed test between both period using Wilcoxon signed rank test and resulting obvions with period I value 0.26 ± 0.20 meters/second and period II value is 0.11 ± 0.12 meters/second along with p value 0.001 (p<0.05). Conclusion: Therefore, based on the result of my research test, we can concluded that the addition of core stability exercise in paddle training program is more effective to increase sculling speed.

scholarly journals The Effect of Health Education on The Knowledge and Adherence of Diet for Gout Arthritis Patients

2021 ◽  
Vol 4 (2) ◽  
pp. 120
Author(s):  
Anatun Aupia
Keyword(s):  
Uric Acid ◽  
Health Education ◽  
Protein Metabolism ◽  
Analysis Data ◽  
The Body ◽  
Rank Test ◽  
P Value ◽  
Adherence To Diet ◽  
Signed Rank ◽  
Signed Rank Test

Uric acid is the result of production by the body, so its quality can be normal in the blood and urine. However, the rest of the protein metabolism of foods containing purines also produces uric acid. One variable that impacts uric acid levels is the knowledge a person has so that a better lifestyle can be improved by providing health education. This research purpose is to establish the effect of health education on knowledge and adherence to the gout diet on gout arthritis patient. Pre-experimental with One group pretest-posttest design has been used in this research. Forty-five respondents were collected using total sampling and a questionnaire was used to measure the data. The analysis data using the Wilcoxon Signed Rank Test showed that the significance value (p-value) is about 0.000 <0.05 which indicate that there is an effect of health education on knowledge and adherence. It can be deduced there is an effect of health education on knowledge and adherence to diet for gout arthritis patients.

scholarly journals The Effectiveness of Dark Chocolate Consumption toward Anxienty of Post Sectio Caesaraea Mother

2016 ◽  
Vol 3 (2) ◽  
pp. 131-135
Author(s):  
Laily Wahidatul Oktavia ◽  
Maria Ulfa
Keyword(s):  
Anxiety Scale ◽  
Dark Chocolate ◽  
Sectio Caesarea ◽  
Rank Test ◽  
P Value ◽  
Post Surgery ◽  
Signed Rank ◽  
Before And After ◽  
Signed Rank Test ◽  
Wilcoxon Rank Test

The consumption of dark chocolate on the second day of mother post section caesarea canreduce anxiety, since the asetosal substance can stimulate the limbic system of hypothalamus to suppressthe anxiety. Method: The research design was a Quasy experimental. The research sample was 8mother post sectio caesarea in Ngudi Waluyo Hospital Cempaka Wlingi at August 14th, up to September14th, 2015, it was chosen using accidental sampling. The data analyzed by Wilcoxon rank test. Result:showed a decrease in the percentage of anxiety scale before and after eating dark chocolate in whichthe anxiety scale of 87.5% to 20%. Based on statistical analysis showed Wlicoxon Signed Rank Test pvalue = 0,008, so p value = 0.008 < = 0.05. Discussion: relaxed condition was needed in the processof recovery condition after partum mothers, especially post surgery. Psychological factors like familysupport also needed to optimize all of the action taken.

UJI BEDA PREFERENSI BELANJA IMPOR BARANG KIRIMAN ATAS PERUBAHAN BATAS PEMBEBASAN BEA MASUK

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Himawan Yusuf
Keyword(s):  
Consumer Preferences ◽  
T Test ◽  
Rank Test ◽  
P Value ◽  
Average Value ◽  
Signed Rank ◽  
Wilcoxon Signed Rank Test ◽  
Before And After ◽  
Initial Hypothesis ◽  
Signed Rank Test

ABSTRACT: Modification of threshold exemption from import duties was tested whether changing consumer preferences in shopping from abroad. This study uses a paired test with the initial hypothesis that there is no difference in the daily average value of imports before and after the policy is applied. The research data is only from the Customs offices which have services for shipment items (32 offices) on October 1, 2019, to March 2, 2020. Descriptive statistical results show that the average was USD135,065, then dropped to USD127,430. Based on the results, both the Paired Sample T Test and The Wilcoxon Signed Rank Test obtained a p-value of 0,000, meaning that the initial hypothesis was rejected. The adoption of this policy has changed the preferences of consumers shopping from abroad. The Government's aim to reduce the trade balance deficit and protect domestic businesses appears to be successful, however, if there are no substitute goods available in the country, the import will only move from importing consignment goods to general imports. The novelty is the variable of import duty on shopping preferences is not widely used. The limitation of this study only measures changes in spending preferences, do not in state revenue.Keywords: shopping preference, consignment, tax exemption, difference test ABSTRAK:Perubahan kebijakan batas pembebasan terhadap bea masuk dan pajak atas impor barang kiriman diuji apakah merubah preferensi konsumen dalam berbelanja barang yang dikirim langsung dari luar negeri melalui mekanisme impor barang kiriman. Penelitian ini menggunakan metode kuantitatif melalui uji berpasangan dengan hipotesis awal tidak adanya perbedaan nilai rerata impor harian baik sebelum maupun setelah kebijakan berlaku. Data penelitian hanya kantor-kantor Bea Cukai yang memiliki pelayanan atas barang kiriman (32 kantor) pada 1 Oktober 2019 sampai dengan 2 Maret 2020. Hasil statistik deskriptif menunjukkan bahwa rerata harian impor sebelum kebijakan tersebut berlaku sebesar USD135.065, kemudian turun menjadi USD127.430. Berdasarkan pengujian, baik pada Paired Sampel T Test maupun pada Wilcoxon Signed Rank Test diperoleh nilai p sebesar 0.000 (hipotesis awal ditolak). Hal ini berarti penerapan kebijakan tersebut telah merubah preferensi belanja dari luar negeri melalui impor barang kiriman. Tujuan Pemerintah untuk mengurangi defisit neraca perdagangan dan melindungi usaha dalam negeri tampaknya berhasil, namun apabila belum tersedia barang subtitusi di dalam negeri, importasi tersebut hanya akan berpindah dari impor barang kiriman menjadi impor umum. Keterbaruan pada penelitian ini adalah variabel bea masuk pada preferensi belanja belum banyak digunakan. Keterbatasan penelitian ini hanya mengukur perubahan preferensi belanja, tidak mengukur perubahan penerimaan negara.Kata Kunci: preferensi belanja, impor barang kiriman, pembebasan pajak, uji beda

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