scholarly journals The Physical Properties and Applications of Gold Nanoparticles (Au NPs): Review

2021 ◽  
Vol 3 (1) ◽  
pp. 74-86
Author(s):  
Rusul Adnan Al-wardy . ◽  
Saad Khalid Rahi .
Keyword(s):  
Drug Delivery ◽  
Quantum Dots ◽  
Gold Nanoparticles ◽  
Physical Properties ◽  
Current Work ◽  
Spherical Nanoparticles ◽  
Au Nps ◽  
3 Dimensional ◽  
Nano Rods ◽  
Catalytic Applications

Nanoparticles of gold that for years have been recognized are the concept of an increasingly rising reports number and of promising for electronic, optical, magnetic, biomedical and catalytic applications in century of 21st. Because of Nanoparticles of gold stability, an interest in such research is a reason for performing the current work. There are various types of AuNPs: Zero-dimensional AuNps: quantum dots, spherical nanoparticles. AuNPs as 1-dimensional: nanowires, nano-rods, nano-belts, nanotubes. AuNPs as 2-dimensional: nano-plates of gold, nano-shell and, AuNPs as 3 dimensional: nano tadpoles of gold, nano- dumbbells of gold (AuNDs), AuNPs being spread, for example, nano-dendrites of gold, nano-pods, and nano-stars. Au NPs, in the field of medicine are investigated for several applications include vectors of drug delivery, agents of contrast, and therapy of localized heat, biomarkers of ultra-sensitive and more. AuNPs are very attractive material for biosensor, chemosensory, genosensor and immunosensor production

Quantum Dots Based Material for Drug Delivery Applications

2021 ◽  
pp. 191-215
Keyword(s):  
Drug Delivery ◽  
Quantum Dots ◽  
Particle Size ◽  
Physical Properties ◽  
Semiconductor Nanoparticles ◽  
Cellular Imaging ◽  
Biological Applications ◽  
Distinct Class ◽  
Imaging Probes ◽  
Biomedical Field

Quantum dots (QDs) have shown promising potential to many biomedical and biological applications, mainly in drug delivery or activation and cellular imaging. These semiconductor nanoparticles, QDs, whose particle size is in the range of 2-10 nanometer with unique photo-chemical and -physical properties that are not possessed by any other isolated molecules, have become one of the distinct class of imaging probes and worldwide platforms for manufacturing of multifunctional nanodevices. In this chapter, properties, applications of QDs, and importance in the biomedical field especially in drug delivery is presented.

scholarly journals Role of Nanobiotechnology in Developing Personalized Medicine for Cancer

2005 ◽  
Vol 4 (6) ◽  
pp. 645-650 ◽  
Author(s):  
K. K. Jain
Keyword(s):  
Drug Delivery ◽  
Quantum Dots ◽  
Gold Nanoparticles ◽  
Molecular Imaging ◽  
Personalized Medicine ◽  
Early Detection ◽  
Early Detection Of Cancer ◽  
Molecular Level ◽  
Cancer Therapies

Personalized medicine simply means the prescription of specific therapeutics best suited for an individual. Personalization of cancer therapies is based on a better understanding of the disease at the molecular level. Nanotechnology will play an important role in this area. Nanobiotechnology is being used to refine discovery of biomarkers, molecular diagnostics, drug discovery and drug delivery, which are important basic components of personalized medicine and are applicable to management of cancer as well. Examples are given of the application of quantum dots, gold nanoparticles, and molecular imaging in diagnostics and combination with therapeutics - another important feature of personalized medicine. Personalized medicine is beginning to be recognized and is expected to become a part of medical practice within the next decade. Personalized management of cancer, facilitated by nanobiotechnology, is expected to enable early detection of cancer, more effective and less toxic treatment increasing the chances of cure.

scholarly journals M13 Phages Uptake of Gold Nanoparticles for Radio- and Thermal-Therapy and Contrast Imaging Improvement

2021 ◽  
Vol 11 (23) ◽  
pp. 11391
Author(s):  
Lorenzo Torrisi ◽  
Letteria Silipigni ◽  
Lubomir Kovacik ◽  
Vasily Lavrentiev ◽  
Mariapompea Cutroneo ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Laser Ablation ◽  
Metallic Nanoparticles ◽  
Average Diameter ◽  
Thermal Therapy ◽  
Low Doses ◽  
Spherical Nanoparticles ◽  
Contrast Imaging ◽  
Au Nps ◽  
Tumoral Cells

The presented work deals with the uptake of gold nanoparticles (Au NPs) by M13 phages in solutions. In particular, the Au NPs uptake modalities and their localization in the filamentous phages are evaluated and measured. Gold spherical nanoparticles (with an average diameter of the order of 10 nm) are obtained by laser ablation in water with a sodium citrated surfactant. The interest of such application comes from the possibility to employ living biological structures to transport heavy metallic nanoparticles inside cells of tumoral tissues. Indeed, phages have the capability to introduce Au NPs in the proximity to the cell nucleus, increasing the efficiency of DNA destruction in the tumoral cells by employing low doses of ionizing radiation during radiotherapy and hyperthermia treatments. Several analyses and microscopy characterizations of the prepared phages samples embedding gold nanoparticles are presented, demonstrating that the presence of Au NPs increases the phages imaging contrast.

scholarly journals Preparation, Functionalization, Modification, and Applications of Nanostructured Gold: A Critical Review

Energies ◽  
2021 ◽  
Vol 14 (5) ◽  
pp. 1278
Author(s):  
Muhammad Yaseen ◽  
Muhammad Humayun ◽  
Abbas Khan ◽  
Muhammad Usman ◽  
Habib Ullah ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Vapor Deposition ◽  
Sol Gel ◽  
Chemical Vapor ◽  
Catalytic Performance ◽  
Direct Oxidation ◽  
Au Nps ◽  
Potential Applications ◽  
Nanostructured Gold ◽  
Catalytic Applications

Gold nanoparticles (Au NPs) play a significant role in science and technology because of their unique size, shape, properties and broad range of potential applications. This review focuses on the various approaches employed for the synthesis, modification and functionalization of nanostructured Au. The potential catalytic applications and their enhancement upon modification of Au nanostructures have also been discussed in detail. The present analysis also offers brief summaries of the major Au nanomaterials synthetic procedures, such as hydrothermal, solvothermal, sol-gel, direct oxidation, chemical vapor deposition, sonochemical deposition, electrochemical deposition, microwave and laser pyrolysis. Among the various strategies used for improving the catalytic performance of nanostructured Au, the modification and functionalization of nanostructured Au produced better results. Therefore, various synthesis, modification and functionalization methods employed for better catalytic outcomes of nanostructured Au have been summarized in this review.

scholarly journals Immobilization of functional nano-objects in living engineered bacterial biofilms for catalytic applications

2019 ◽  
Vol 6 (5) ◽  
pp. 929-943 ◽  
Author(s):  
Xinyu Wang ◽  
Jiahua Pu ◽  
Yi Liu ◽  
Fang Ba ◽  
Mengkui Cui ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Quantum Dots ◽  
Gold Nanoparticles ◽  
Organic Dyes ◽  
High Energy ◽  
Genetically Engineered ◽  
Bacterial Biofilms ◽  
Proof Of Concept ◽  
Catalytic Applications ◽  
Cellular Components

Abstract Nanoscale objects feature very large surface-area-to-volume ratios and are now understood as powerful tools for catalysis, but their nature as nanomaterials brings challenges including toxicity and nanomaterial pollution. Immobilization is considered a feasible strategy for addressing these limitations. Here, as a proof-of-concept for the immobilization of nanoscale catalysts in the extracellular matrix of bacterial biofilms, we genetically engineered amyloid monomers of the Escherichia coli curli nanofiber system that are secreted and can self-assemble and anchor nano-objects in a spatially precise manner. We demonstrated three scalable, tunable and reusable catalysis systems: biofilm-anchored gold nanoparticles to reduce nitro aromatic compounds such as the pollutant p-nitrophenol, biofilm-anchored hybrid Cd0.9Zn0.1S quantum dots and gold nanoparticles to degrade organic dyes and biofilm-anchored CdSeS@ZnS quantum dots in a semi-artificial photosynthesis system for hydrogen production. Our work demonstrates how the ability of biofilms to grow in scalable and complex spatial arrangements can be exploited for catalytic applications and clearly illustrates the design utility of segregating high-energy nano-objects from injury-prone cellular components by engineering anchoring points in an extracellular matrix.

Facile synthesis of thermo-responsive episulfide group-containing diblock copolymers as robust protecting ligands of gold nanoparticles for catalytic applications

RSC Advances ◽  
2016 ◽  
Vol 6 (44) ◽  
pp. 37487-37499 ◽  
Author(s):  
Dongmei Wang ◽  
Bingxin Liu ◽  
Jianhua Lü ◽  
Changli Lü
Keyword(s):  
Gold Nanoparticles ◽  
Catalytic Activity ◽  
Diblock Copolymers ◽  
Colloidal Stability ◽  
High Catalytic Activity ◽  
Facile Synthesis ◽  
Au Nps ◽  
Catalytic Applications

Well-defined novel thermo-responsive diblock copolymers containing episulfide ligand stabilized Au NPs show interesting assembly morphologies, excellent colloidal stability and high catalytic activity for the reduction of 4-nitrophenol.

Synthesis of Chitosan-Gold Nanoparticles for Drug Delivery

2014 ◽  
Vol 896 ◽  
pp. 280-283 ◽  
Author(s):  
Hanani Yazid ◽  
Amirah Mohd Yassin ◽  
Ahmad Zahid Ruslan ◽  
Siti Hajar Alias ◽  
Rohana Adnan ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Particle Size ◽  
Gold Nanoparticles ◽  
Environmental Remediation ◽  
Gold Salt ◽  
Au Nps ◽  
Chitosan Concentration ◽  
Wide Range ◽  
Potential Applications ◽  
Au Particle Size

Gold nanoparticles (Au NPs) have potential applications in catalysis, drug delivery, sensors and environmental remediation. This wide range application is due to its amenability of synthesis and functionalization, less toxicity and ease of detection. The present work focuses on functionalization of Au NPs with chitosan for further application in biomedical research. Gold nanoparticles (Au NPs) functionalized chitosan were prepared by reducing gold salt solution at various pH medium in the presence of sodium borohydride. The effect of pH and chitosan concentration on the Au particle size and distribution are studied. The results revealed the dependence of Au particle size on the pH of the solution. The smallest Au particle size is found to form in a range of 10.22 ± 2.96 nm at 0.2% chitosan concentration. In this study, we anticipate the Au NPs functionalized chitosan can be used for drug delivery applications.

scholarly journals Gold Nanoparticles for Drug Delivery and Cancer Therapy

2020 ◽  
Vol 10 (11) ◽  
pp. 3824 ◽  
Author(s):  
Sarkar Siddique ◽  
James C. L. Chow
Keyword(s):  
Drug Delivery ◽  
Gold Nanoparticles ◽  
Cancer Therapy ◽  
Rapid Development ◽  
Disease Diagnosis ◽  
The Novel ◽  
Au Nps ◽  
Functionalized Nanomaterials ◽  
Cancer Agent ◽  
Gold Nanomaterials

Nanomaterials are popularly used in drug delivery, disease diagnosis and therapy. Among a number of functionalized nanomaterials such as carbon nanotubes, peptide nanostructures, liposomes and polymers, gold nanoparticles (Au NPs) make excellent drug and anticancer agent carriers in biomedical and cancer therapy application. Recent advances of synthetic technique improved the surface coating of Au NPs with accurate control of particle size, shape and surface chemistry. These make the gold nanomaterials a much easier and safer cancer agent and drug to be applied to the patient’s tumor. Although many studies on Au NPs have been published, more results are in the pipeline due to the rapid development of nanotechnology. The purpose of this review is to assess how the novel nanomaterials fabricated by Au NPs can impact biomedical applications such as drug delivery and cancer therapy. Moreover, this review explores the viability, property and cytotoxicity of various Au NPs.

Gold nanoparticles decorated on a graphene-periodic mesoporous silica sandwich nanocomposite as a highly efficient and recyclable heterogeneous catalyst for catalytic applications

RSC Advances ◽  
2015 ◽  
Vol 5 (42) ◽  
pp. 33423-33431 ◽  
Author(s):  
Siyavash Kazemi Movahed ◽  
Monire Shariatipour ◽  
Minoo Dabiri
Keyword(s):  
Gold Nanoparticles ◽  
Mesoporous Silica ◽  
Heterogeneous Catalyst ◽  
Au Nanoparticles ◽  
The Novel ◽  
Au Nps ◽  
Highly Efficient ◽  
Nanocomposite Catalyst ◽  
Catalytic Applications ◽  
Recyclable Heterogeneous Catalyst

Ultra-small Au nanoparticles (Au NPs) were immobilized on HS-functionalized sandwich-like periodic mesoporous silica (PMS) coated graphene (G) to form the novel nanocomposite catalyst Au NPs@HS-G-PMS.

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