scholarly journals Prevalence and Associated Factors of Regular Nonsteroidal Anti-inflammatory Drugs used in a Rural Community, Thailand

2017 ◽  
Vol 9 (9) ◽  
pp. 58 ◽  
Author(s):  
Pongsom Luanghirun ◽  
Patid Tanaboriboon ◽  
Pawaris Mahissarakul ◽  
Chanikarn Tongruang ◽  
Chanita Chaichirawiwat ◽  
...  
Keyword(s):  
Side Effects ◽  
Qualitative Study ◽  
Associated Factors ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Factors Associated ◽  
Attitudes And Practices ◽  
Pain Medications ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

BACKGROUND: In Thailand, 67.2% of the population widely uses analgesics including nonsteroidal anti-inflammatory drugs (NSAIDs), which may lead to serious side effects. However, the information of regular NSAIDs used in Thailand is still limited.METHODS: A mixed method cross-sectional study was conducted. Quantitative data were collected using questionnaires to determine the prevalence and factors associated with regular NSAID use. The qualitative study was conducted using group and in-depth interviews to determine the knowledge, attitudes and practices of NSAID users.RESULTS: Of 771 participants, the prevalence of NSAID use was 31.1 and regular NSAID use was 7.4. Age, pain at the hips or thighs and pain score were independent factors associated with regular NSAID use. The qualitative study indicated that the use of NSAIDs was influenced by drug effectiveness, sources of NSAIDs and consideration of benefits and risks of the drugs.CONCLUSION: This was the first report on the prevalence and associated factors of regular NSAID use in Thailand. In this community, nonprescribed NSAIDs might cause some serious side effects and undesirable drug interaction. Information on side effects of pain medications should be disseminated to the public including guidelines on how to use pain medications.

scholarly journals PREVALENCE OF PREMATURE EJACULATION AND ERECTILE DYSFUNCTION AND THEIR ASSOCIATED FACTORS AMONG URBAN AND RURAL POPULATION OF MALAYSIA

2017 ◽  
Vol 17 (3) ◽  
pp. 86-96 ◽  
Author(s):  
Mohd Rohaizat Hassan ◽  
Mohd Fadhli Samsuri ◽  
Shamsul Azhar Shah ◽  
Nazarudin Safian ◽  
Zulkifli Md Zainuddin ◽  
...  
Keyword(s):  
Erectile Dysfunction ◽  
Rural Areas ◽  
Rural Population ◽  
Associated Factors ◽  
Premature Ejaculation ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated ◽  
Urban And Rural Areas

The purpose of this study was to determine the prevalence and factors associated with of Premature Ejaculation &Erectile Dysfunctionamong Malaysian men. A cross-sectional study was conducted in urban and rural areas using standardized and validated self-administered questionnaires. A total of 319 samples were recruited for PE screening. The overall prevalence of PE was 31.7% with 20.7% and 40.8% for urban and rural area respectively. Depression, anxiety and frequent masturbation were significantly associated with PE. While For ED, infrequent sexual intercourse was the sole factor significantly associated with ED.PE and ED were highly prevalent in both urban and rural areas; with several significant preventable associated factors.

Non-Steroidal Anti-Inflammatory Drugs: Usage and Co-prescription with Other Potentially Interacting Drugs in Elderly: a Cross-sectional Study

2019 ◽  
Author(s):  
Nuru Abdu ◽  
Samuel Teweldemedhin ◽  
Asmerom Mosazghi ◽  
Luwam Asfaha ◽  
Makda Teshale ◽  
...  
Keyword(s):  
Adverse Effects ◽  
Drug Interactions ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Female Ratio ◽  
Protective Agents ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Abstract Introduction: Globally, non-steroidal anti-inflammatory drugs (NSAIDs) usage in the elderly with chronic pain has been reported as frequent. Though it is fundamental in maintaining their quality of life, the risk of polypharmacy, drug interactions and adverse effects is of paramount importance as the elderly usually require multiple medications for their co-morbidities. If prescriptions are not appropriately monitored and managed, they are likely to expose patients to serious drug interactions and potentially fatal adverse effects. Thus, the objective of the study was to assess the appropriateness of NSAIDs use and incidence of NSAIDs related potential interactions in elderly. Methods: A descriptive cross-sectional study was conducted among elderly out-patients (aged 60 and above) who visited three hospitals in Asmara between August 22 and September 29, 2018. The sampling design was two-stage random sampling and data was collected using a questionnaire, exit interview and by abstracting information from patients’ clinical cards. Descriptive and analytical statistics including chi-square test and logistic regression were employed using SPSS. Results: A total of 285 elderly respondents were enrolled in the study with similar male to female ratio. One in four of all respondents were chronic NSAIDs users, of which 74.6% were not prescribed prophylactic gastro-protective agents (GPAs). About 20% of the elderly were involved in polypharmacy and nearly all of the encountered potential NSAIDs related interactions (n=322) with prescribed drugs were moderate. Diabetes and hypertension were significantly associated with chronic NSAIDs use (OR=3, 95% CI: 1.54, 5.84; OR=9.99, 95% CI: 4.46, 22.38) and incidence of drug interactions (OR=3.95, 95%CI: 1.92, 8.13; OR=3.12, 95%CI: 1.81, 5.33) while diabetes and cardiac problem were significantly associated with incidence of polypharmacy (OR=4.33, 95% CI: 2.36, 7.96; OR=3.56, 95% CI: 1.05, 12.11). Conclusion: Though the overall reflection of prescription pattern of NSAIDs during the study period was almost satisfactory, gastro-protective agents were poorly prescribed as a prophylaxis.

Prelacteal Feeding and Associated Factors Among Northwestern Ethiopian Women Having Children Less than Six Months Age: A Community Based Cross- Sectional Study

2020 ◽  
Author(s):  
Maezu G/slassie1 ◽  
Kiflay Mulugeta ◽  
Abraha Teklay Berhe
Keyword(s):  
Breast Feeding ◽  
Associated Factors ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Prelacteal Feeding ◽  
Community Based ◽  
Cross Sectional ◽  
Timely Initiation ◽  
Factors Associated

Abstract Background: Prelacteal feeding is administration of any food or fluid other than breast milk before initiation of breast feeding. Optimal breastfeeding including discouraging prelacteal feeding could save 823,000 lives per year among children ages five years old and younger. Despite of this mothers give prelacteal feeding to their child in different part of Ethiopia; However, there is a paucity of information on prevalence of prelacteal feeding and associated factors in the study area. Thus, the current study aimed at determining of the prevalence of prelacteal feeding and associated factors among mothers of children aged less than six months in Gozamen district, East Gojjam zone, North West Ethiopia, 2019-2020Methods: A community -based cross-sectional study was conducted among 741 mothers of children aged less than six months in Gozamen district from August 2019 to Feb 2020. Stratified cluster sampling technique was used to select study participants. Data were collected by face to face interviewer-administered, pretested and semi-structured questionnaire. Descriptive analysis, bi-variable and multivariable logistic regression model were employed. Adjusted odds ratio with 95% confidence interval was used to identify factors associated with prelacteal feeding.Results: In this study the prevalence of prelacteal feeding was found to be 17.1%with 95%CI [14.3, 20]. Mothers who had no ANC follow up [AOR: 7.53, CI; 3.32, 17.05], those mothers who did not discard colostrum [AOR: 0.12, CI; 0.07, 0.12] time of breast feeding initiation [AOR: 3.53, CI; 2.05, 6.11] and mothers who had single ANC visit [AOR: 2.98, CI; 1.52, 5.85] were significant independent factors associated with prelacteal feeding.Conclusion: This study concluded that prelacteal feeding was high in the study area .Therefore, in order to tackle this problem strengthening antenatal follow up, timely initiation of breastfeeding, health education and awarenes creation of the communities are recommended interventions.

scholarly journals Internet Addiction and its Associated Factors Among Dilla University Undergraduate Students, Dilla, Ethiopia, 2019: A Cross-Sectional Study

2021 ◽  
Author(s):  
Nebiyu Mengistu ◽  
Desalegn Tarekegn ◽  
Wondwosen Molla ◽  
Seid Shumye
Keyword(s):  
Logistic Regression ◽  
University Students ◽  
Undergraduate Students ◽  
Internet Addiction ◽  
Associated Factors ◽  
Internet Use ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated

Abstract Background: Internet addiction is characterized by excessive or poorly controlled preoccupation, urges or behavior regarding computer use and internet access that lead to impairment or distress. Globally, it has been found that the occurrence rate of internet addiction among university students ranges from 0.8% to 47.7%. Despite, there are multiple challenges that related with internet addiction which remains under-recognized and largely ignored by stakeholders and also not well known especially in low income countries including Ethiopia. Therefore, this study was conducted aimed to assess the magnitude of the internet addiction and its associated factors among undergraduate students. Methods: Institutional based cross-sectional study was employed from May 1st to June 1st 2019. Multi-stage sampling technique was used to get a total of 846 undergraduate Students. Data was collected by using self-administered structured questionnaires of Young’s Internet Addiction Test. The collected data was coded and entered into EPIDATA 3.1 and analyzed by using SPSS version 22, Bivariate and multivariate logistic regression analysis was conducted to identify factors associated with internet addiction and statistically significant was considered at P-value <0.05. Results: A total of 846 study participants, giving a response rate were 761 (90%) and the prevalence of internet addiction was 19.4%. Multiple logistic regression model revealed that being male [AOR=1.69, 95% CI: (1.80, 6.41)], probable depression [AOR =3.61, 95% CI (2.40, 5.43)] and khat or caffeinated drinks [AOR=1.86, 95%CI: (1.21, 2.87)] were significantly associated with internet addiction.Conclusion: This study revealed that a high prevalence of internet addiction among Dilla university students and there were various factors associated with increased prevalence of problematic internet use. Therefore, students need to be educated about safe, valuable, and healthy practice of internet use and better to counsel on substance use and its consequences and also psychiatric evaluation (referring for mental health services) to overcome the anticipated increase in internet addiction

scholarly journals Early implanon discontinuation and associated factors among women ever used implanon in Mettu district, Oromia regional state, southwest Ethiopia, 2021

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Hana Tesfaye ◽  
Ebissa Negara ◽  
Kenbon Bayisa
Keyword(s):  
Side Effects ◽  
Associated Factors ◽  
Statistical Significance ◽  
Descriptive Analysis ◽  
Sampling Technique ◽  
Cross Sectional Study ◽  
Relative Effect ◽  
Outcome Variable ◽  
P Value ◽  
Cross Sectional

Abstract Background Implanon is an effective form of long-acting reversible contraceptive used to prevent conception with a clinical failure rate of less than one per 100 users. However, in sub-Saharan countries the utilization of implanon was very low. Regardless of low utilization; its early discontinuation is very common in most developing countries including Ethiopia. Objectives To assess the prevalence of early implanon discontinuation and associated factors among women ever used implanon in Mettu district. Methods A community based cross-sectional study design was conducted from October 11 to December 4, 2020 G C. A total of 430 women were included in the study by systematic random sampling technique. Data were entered into epi data version 3.1 and analyzed by SPSS version 25.0. Descriptive analysis was computed to describe descriptive results. Logistics regression was computed to see the relative effect of factors on the outcome variable. Adjusted odds ratio was calculated with 95% confidence intervals to show strength of association and p-value < 0.05 was used to declare statistical significance. The finding of the study was presented using narrations, tables and chart. Result The total proportion of early implanon discontinuation among 430 mothers was 19.3%. Women who did not counseled about the presence of alternatives methods [AOR = 2.28: 95% CI (1.22–4.26)], women who experienced dizziness after insertion of implanon [AOR = 1.90: 95% CI (1.06–3.43)] and being having menstrual disturbance after insertion of implanon [AOR = 2.17: 95% CI (1.16–4.08)] were significantly associated with early implanon discontinuation. Women who were counseled about the advantage of implanon [AOR: 0.49: 95% CI (0.28–0.87)] were protective from early implanon discontinuation. Conclusion and recommendation Early implanon discontinuation among mothers was found to be high. Hence, effective counseling on advantages and side effects of implanon and proper management of the side effects should be made to increase implanon retention.

scholarly journals Magnitude of preterm hospital neonatal mortality and associated factors in northern Ethiopia: a cross-sectional study

BMJ Open ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. e051161
Author(s):  
Bekahegn Girma ◽  
Jemberu Nigussie
Keyword(s):  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Neonatal Mortality ◽  
Associated Factors ◽  
Distress Syndrome ◽  
Cross Sectional Study ◽  
Northern Ethiopia ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated

ObjectiveThis study aimed to assess the magnitude of preterm neonatal mortality in hospitals and associated factors in northern Ethiopia.DesignInstitutional-based cross-sectional study.SettingComprehensive specialised hospitals in the Tigray region, northern Ethiopia.ParticipantsPreterm neonates admitted in Ayder and Aksum comprehensive specialised hospitalsPrimary outcomeMagnitude of preterm neonatal mortality.Secondary outcomeFactors associated with preterm neonatal mortalityResultThis study was conducted from 1 April 2019 to 15 May 2019 among 336 participants with a response rate of 96.8%. The magnitude of preterm neonatal mortality was 28.6% (95% CI: 24.0 to 33.7). In multivariable logistic regression, respiratory distress syndrome (adjusted odd ratio (AOR)=2.85; 95% CI: 1.35 to 6.00), apnoea of prematurity (AOR=5.45; 95% CI: 1.32 to 22.5), nulli parity (AOR=3.63; 95% CI: 1.59 to 8.24) and grand parity (AOR=3.21; 95% CI: 1.04 to 9.94) were significant factors associated with preterm neonatal mortality. However, receiving Kangaroo mother care (AOR=0.08; 95% CI: 0.03 to 0.20) and feeding initiated during hospitalisation (AOR=0.07; 95% CI: 0.03 to 0.15) were protective against preterm neonatal mortality.ConclusionsThe magnitude of preterm neonatal mortality in hospitals was still high. Interventions geared towards curbing preterm in-hospital neonatal mortality should strengthen early diagnosis and treatment of preterm newborns with respiratory distress syndrome and apnoea of prematurity; while concomitantly reinforcing the implementation of kangaroo care and early feeding initiation is important.

scholarly journals Magnitude of optimal adherence and predictors for a low level of adherence among HIV/AIDS-infected adults in South Gondar zone, Northwest Ethiopia: a multifacility cross-sectional study

BMJ Open ◽  
2022 ◽  
Vol 12 (1) ◽  
pp. e056009
Author(s):  
Shimeles Biru Zewude ◽  
Tewodros Magegnet Ajebe
Keyword(s):  
Associated Factors ◽  
Cross Sectional Study ◽  
Northwest Ethiopia ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated ◽  
Low Level ◽  
South Gondar ◽  
Hiv Aids

ObjectivesThis study aims to identify levels of adherence to antiretroviral therapy (ART) drugs and factors associated with them in Northwest Ethiopia. We hypothesise that in the era of COVID-19, there would be suboptimal adherence to ART drugs.DesignAn observational cross-sectional study was conducted. Factors associated with the level of adherence were selected for multiple logistic regressions at a p value of less than 0.2 in the analysis. Statistically significant associated factors were identified at a p value less than 0.05 and adjusted OR with a 95% CI.SettingThe study was conducted in one specialised hospital and three district hospitals found in the South Gondar zone, Northwest Ethiopia.ParticipantsAbout 432 people living with HIV/AIDS receiving highly active ART in South Gondar zone public hospitals and who have been on treatment for more than a 3-month period participated in the study.Primary and secondary outcome measuresLevels of adherence to ART drugs and their associated factors.ResultsAmong 432 study participants, 81.5% (95% CI: 78% to 85.2%) of participants were optimally adherent to ART drugs. Determinants of a low level of adherence: stigma or discrimination (OR=0.4, p=0.016), missed scheduled clinical visit (OR=0.45, p=0.034), being on tuberculosis treatment (OR=0.45, p=0.01), recent CD4 cell count less than 500 cells/mm3 (OR=0.3, p=0.023) and patients who had been on WHO clinical stage III at the time of ART initiation (OR=0.24, p=0.027) were factors significantly associated with adherence to ART drugs.ConclusionsLevel of adherence was relatively low compared with some local studies. The intervention targeted to reduce discrimination, counselling before initiation of treatment and awareness regarding compliance is advised to improve adherence to antiretroviral regimens.

scholarly journals Patients’ Adherence to Anti-diabetic Medications and Associated Factors in Mizan-Tepi University Teaching Hospital: A Cross-Sectional Study

2021 ◽  
Vol 58 ◽  
pp. 004695802110674
Author(s):  
Jafer Siraj ◽  
Turi Abateka ◽  
Oliyad Kebede
Keyword(s):  
Side Effects ◽  
Drug Use ◽  
Associated Factors ◽  
Cross Sectional Study ◽  
University Teaching ◽  
P Value ◽  
Diabetic Patients ◽  
Sectional Study ◽  
Monthly Income ◽  
Cross Sectional

Introduction: A number of medications have been demonstrated to lower blood glucose. However, current-day management has failed to achieve and maintain the optimal glycemic level for diabetic patients. Patients’ non-adherence is among the most contributing factors. Therefore, the aim of this study was to explore the prevalence of non-adherence to anti-diabetic medications and associated factors. Methods: A hospital based cross-sectional study was conducted from November 2020 to January 2021. A systematic random sampling technique was used. Data were collected by structured questionnaire adapted from different literatures. Then, data were entered into SPSS version 25 and analyzed. To determine the association of dependent and independent variables, multiple logistic regression was done. P-value <.05 was considered statistically significant. Results: A total of 275 study participants were interviewed with a response rate of 100%. From this 53.8% were females, 59.3% were in the age group of 41-60 years, 35.3% were college/university graduates and 79.3% were not using social drugs. One hundred eighty-seven (68%) of them were adherent to their anti-diabetic medication. Factors found to be significantly associated with anti-diabetic medication adherence were age >60 years (AOR = .276, 95% CI = .124-.611) attending higher education (AOR = 6.203, 95% CI = 1.775-21.93), retired (AOR = 7.771, 95% CI = 1.458-41.427), housewife (AOR = 7.023, 95% CI = 1.485-33.215), average monthly income 1001birr-2000 birr (AOR = .246, 95% CI = .067-.911) and social drug use (AOR = 3.695, 95% CI = 1.599-8.542). Forgetfulness, not affording, side effects, misunderstanding of instructions, and poly-pharmacy were identified reasons for non-adherence. Conclusions and Recommendations: Patients’ adherence to anti-diabetic medications in the current study is sub-optimal. Age, monthly income, level of education, occupational status, and social drug use were associated with adherence. Forgetfulness, not affording, and side effects were reasons identified to contribute to non-adherence. Therefore, adherence counseling, use of alarms, and the way to mitigate non-affordability, including anti-diabetic medications into a program drug should be considered.

scholarly journals Magnitude of self-medication practice and the associated factors among adult household members living in western region, Tanzania

2021 ◽  
Author(s):  
Mussa S. Manhyabili ◽  
George M. Bwire ◽  
Lubinza Maziku ◽  
Mecky .I. N. Matee
Keyword(s):  
Side Effects ◽  
Health Care Professionals ◽  
Household Income ◽  
Cross Sectional Study ◽  
University Education ◽  
Self Medication ◽  
Cross Sectional ◽  
Medication Practice ◽  
Factors Associated ◽  
Household Members

Abstract Background: Self-medication practice (SMP) is the use of medication without the prescription of health care professionals. The major problems associated with self-medication practice have been drug resistance, drug side effects, wastage of resources, and serious health hazards including death. This study was conducted to assess the magnitude and factors associated with self-medication practice among adult household members in Shinyanga Municipal Council (SMC).Methods: A community based cross-sectional study was conducted in SMC, in September and October 2020. A multistage cluster random sampling was used to select study participants. Variables such as socio-demographic factors and reasons for SMP were summarized using frequencies and percentages. Chi square and logistic regression test were used to identify factors associated with SMP. All statistics were done using SPSS version 25.Results: In total 422 adult household members were studied, the magnitude of SMP among adult household members in SMC was 86%. The major symptom of illness that lead to SMP were headache 75(38.9%), fever 71 (37%) and cough 52 (27.1%) while paracetamol 84(43.8%), Ampiclox 30 (15.5%) and artemether lumefantrine 25 (13%) were the commonly used drugs. Perceptions of illness as mild 141(38.8%)and previous experience of self-medication138(38%) were the reasons for SMP. Participants who did not complete secondary education were seven times more likely to practice SMP as compared to those who had university education (adjusted odds ratio [aOR] =7.136, 95%CI=1.447-35.180, P=0.016). Participants with average household income (AHI) (<180,000 TSH=<78USD) were less likely to practice SMP compared to those with AHI (B 180,000Tsh) (aOR = 0.424, 95%CI = 0.214 – 0.840, P = 0.014).Conclusion: The magnitude of SMP in Shinyanga Municipal was found to be high.SMP was significantly associated with level of education and average monthly household income. Strengthening of the community’s awareness on the side effects of SMP including antimicrobial resistance in the study area is recommended.

scholarly journals Potential and clinical relevant drug-drug interactions among elderly from nursing homes: a multicentre study in Murcia, Spain

2019 ◽  
Vol 24 (5) ◽  
pp. 1895-1902
Author(s):  
Carles Iniesta-Navalón ◽  
Juan Jose Gascón-Cánovas ◽  
Zenewton André da Silva Gama ◽  
José Francisco Sánchez-Ruiz ◽  
Erick Angelico Gutiérrez-Estrada ◽  
...  
Keyword(s):  
Nursing Homes ◽  
Drug Interactions ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated ◽  
Complex Sampling ◽  
Inflammatory Drugs ◽  
Multi Level ◽  
Relevant Factors

Abstract This study purposes to determine the prevalence of potential and clinical relevant Drug-Drug-Interactions (pDDIs) in institutionalized older adults and to identify the pertinent factors associated. We conduct an observational, multicenter and cross-sectional study during the last quarter of 2010. We selected a sample of 275 subjects (aged ≥ 65 years) from 10 nursing homes of Murcia (Spain) by a two-stage complex sampling. pDDIs were identified using the College of Pharmacists Database. We only considered pDDIs of clinical relevance, and thereafter the relevant factors were identified through uni-level and multi-level regression analyses. A total of 210 pDDIs were identified, 120 of which were considered clinically relevant (57.1%), affecting a total of 70 elderly (25.8%). Eight pharmacological groups made up 70.2% of the clinically relevant pDDIs. More clinically relevant DDIs were found in people suffering several pathologies (OR = 2.3; 95%CI = 1.4-4.5), and also in people who take ten or more drugs daily (OR = 9.6; 95%CI = 4.8-19.1), and people who take anti-inflammatory drugs (OR = 3.9; 95%CI = 1.4-10.4). This study reveals that clinically relevant pDDIs are very common in institutionalized elderly people, and that caregivers should aim at improving their practice in order to reduce the prevalence of this phenomenon.

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