The use of state-of-the-art haemostatic materials in gastrointestinal surgery

2021 ◽  
Vol 93 (1) ◽  
pp. 49-54
Author(s):  
Alicja Przywózka-Suwał ◽  
Bartosz Ziółkowski ◽  
Marek Szczepkowski
Keyword(s):  
Anastomotic Leakage ◽  
Gastrointestinal Surgery ◽  
Ease Of Use ◽  
Bleeding Complications ◽  
Scientific Publications ◽  
Collagen Matrices ◽  
Conscious Decision ◽  
Cochrane Database ◽  
Wide Range ◽  
Human Thrombin

Haemostatic materials such as: gelatine sponges, oxygenated cellulose meshes, tissue sealants, collagen matrices with human thrombin and fibrinogen are gaining on popularity in gastrointestinal surgery, especially in colorectal surgery. We searched for available scientific publications in the Pubmed and Cochrane database on the use of individual hemostatic materials in the field of gastrointestinal surgery. The analysis focused on the assessment of the safety of the use of individual materials in terms of the rate of bleeding complications and the rate of anastomotic leakage cases. The use of haemostatic materials has for years been a recognized method of reducing the rate of intra- and postoperative complications, both in gastrointestinal surgery and in other surgical specialties. Based on the available studies, it can be concluded that the use of hemostatic materials such as matrices, sponges and adhesives in gastrointestinal surgery, even in patients at high risk of anastomotic leakage and bleeding complications, reduces the incidence of complications. The growing popularity of haemostatics and sealants in surgery means that they are currently used in a wide range of indications, and surgeons are more and more willing to use them even in case of standard surgical procedures, which is reflected in the available studies. Choosing a haemostat should be a conscious decision, taking into account the site and type of bleeding, mechanism of action, ease of use, efficacy, safety, and price, among others.

From the history of the development of electronic dictionaries: foreign and domestic experience

2020 ◽  
Vol 11 (1) ◽  
pp. 6-12
Author(s):  
O. Y. Balalaieva ◽  
Keyword(s):  
Human Activity ◽  
Current Level ◽  
Ease Of Use ◽  
Advanced Search ◽  
Wide Range ◽  
Promising Area ◽  
History Of ◽  
Machine Readable ◽  
Everyday Communication ◽  
Educational Professional

The purpose of the article is to study the dynamics of electronic dictionaries development abroad and in Ukraine using methods of analysis of scientific sources, comparison, generalization and systematization. Electronic dictionaries have been found to be a relatively new phenomenon in the lexicographic market, evolving from machine-readable dictionaries, exact copies of paper editions to complex digital lexicographic systems with a powerful arsenal of functions over the decades. The stages of development of autonomous and online dictionaries are described. Electronic dictionaries due to the advanced search capabilities, speed, simplicity, ease of use, accessibility and compactness have gained popularity among a wide range of users. Today they are used in many spheres of human activity – scientific, educational, professional, everyday communication. However, the analysis of the current level of development of Ukrainian electronic resources indicates a shortage of electronic dictionaries both common and terminological vocabulary. The lack of electronic dictionaries is due to a number of objective problems, both practical and theoretical, that is why research in the field of domestic computer lexicography is a promising area of further research.

Network Organizational Structure (a Scientific and Practical Review)

2020 ◽  
Vol 26 (6) ◽  
pp. 613-618
Author(s):  
A. V. Altukhov ◽  
S. A. Tishchenko
Keyword(s):  
Organizational Structure ◽  
Network Structure ◽  
Business Models ◽  
Scientific Development ◽  
Network Structures ◽  
Scientific Publications ◽  
Wide Range ◽  
Modern Business ◽  
History Of ◽  
Business Structures

The presented study reviews practically relevant research papers in the field of network structures, modern network business models and platforms.Aim. The study aims to elaborate and explain the concept of network structure and platform and to show the reasons for the progressiveness and potential of network organizational structure at the current stage of socio-economic and scientific development.Tasks. The authors highlight the main scientific ideas about network structures in business, including significant studies in this area; provide and explain the main terms and definitions and examine the key characteristics of network business structures; characterize “platforms” as an important concept for modern business and show the relationship between platforms and network structures.Methods. This study uses analysis of information and subsequent synthesis of new knowledge in the form of the authors’ conclusions and a wide range of relevant scientific publications of Russian and foreign authors, including original publications in English and French.Results. The history of network structures is briefly provided. Definitions and characteristics of such concepts as “network structure” and “platform” in relation to business are provided and explained by the authors.

scholarly journals Combination of InnoSEAL plus TR band compared with TR band alone for radial artery outcomes in patients undergoing transradial coronary intervention (InnoSEAL-II): an open-label randomised controlled trial (protocol)

BMJ Open ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. e042101
Author(s):  
Saba Aijaz ◽  
Sana Sheikh ◽  
Asad Pathan
Keyword(s):  
Randomised Controlled Trial ◽  
Radial Artery ◽  
Controlled Trial ◽  
Coronary Intervention ◽  
Ease Of Use ◽  
P Value ◽  
Radial Compression ◽  
Open Label ◽  
Scientific Publications ◽  
Randomised Controlled

IntroductionAbout 2%–30% of cardiac catheterisation procedures get complicated by radial artery occlusion (RAO). Ensuring patent haemostasis appears to be an important factor in reducing RAO. Currently employed method is a radial compression device (RCD) such as transradial band (TRB) that take hours to achieve haemostasis and cause discomfort to the patients. Haemostatic pads offer an alternative to RCD with reduced time to achieve haemostasis. Our trial aims to determine the non-inferiority of the catecholamine chitosan-based pad (InnoSEAL haemostatic pad) used in conjunction with TRB (InnoSEAL +TRB) when compared with the TRB alone in reducing composite adverse access site outcomes.Methods and analysisIt will be an open-label, parallel, randomised controlled trial on 714 adult patients (325 in each arm) undergoing coronary procedure using transradial approach at a cardiac health facility over 7 months duration. InnoSEAL patch along with TRB will be used to control bleeding in intervention arm and TRB alone in control arm, which is the standard practice. Study primary outcomes include RAO and haematoma; secondary outcomes are compression time, patient discomfort, time to discharge and ease of use of the intervention technique by the healthcare staff. χ2 test will be used to compare the categorical outcomes between two arms and student’s t-test for continuous outcomes. A p value of <0.05 will be considered significant.Ethics and disseminationEthical approval for the study has been obtained from the Institutional Review Board of Tabba Heart Institute number IORG0007863. Findings will be disseminated through seminars and scientific publications.Trial registration numberNCT04380883; Pre-results.

scholarly journals Selective Decontamination of the Digestive Tract to Prevent Postoperative Pneumonia and Anastomotic Leakage after Esophagectomy: A Retrospective Cohort Study

Antibiotics ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 43
Author(s):  
Robin Janssen ◽  
Frans Van Workum ◽  
Nikolaj Baranov ◽  
Harmen Blok ◽  
Jaap ten Oever ◽  
...  
Keyword(s):  
Cohort Study ◽  
Anastomotic Leakage ◽  
Digestive Tract ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Protective Factor ◽  
Gastrointestinal Surgery ◽  
Surgical Site Infections ◽  
Selective Decontamination ◽  
Postoperative Pneumonia

Infectious complications occur frequently after esophagectomy. Selective decontamination of the digestive tract (SDD) has been shown to reduce postoperative infections and anastomotic leakage in gastrointestinal surgery, but robust evidence for esophageal surgery is lacking. The aim was to evaluate the association between SDD and pneumonia, surgical-site infections (SSIs), anastomotic leakage, and 1-year mortality after esophagectomy. A retrospective cohort study was conducted in patients undergoing Ivor Lewis esophagectomy in four Dutch hospitals between 2012 and 2018. Two hospitals used SDD perioperatively and two did not. SDD consisted of an oral paste and suspension (containing amphotericin B, colistin, and tobramycin). The primary outcomes were 30-day postoperative pneumonia and SSIs. Secondary outcomes were anastomotic leakage and 1-year mortality. Logistic regression analyses were performed to determine the association between SDD and the relevant outcomes (odds ratio (OR)). A total of 496 patients were included, of whom 179 received SDD perioperatively and the other 317 patients did not receive SDD. Patients who received SDD were less likely to develop postoperative pneumonia (20.1% vs. 36.9%, p < 0.001) and anastomotic leakage (10.6% vs. 19.9%, p = 0.008). Multivariate analysis showed that SDD is an independent protective factor for postoperative pneumonia (OR 0.40, 95% CI 0.23–0.67, p < 0.001) and anastomotic leakage (OR 0.46, 95% CI 0.26–0.84, p = 0.011). Use of perioperative SDD seems to be associated with a lower risk of pneumonia and anastomotic leakage after esophagectomy.

Designing Soft Reactive Adhesives by Controlling Polymer Chemistry

MRS Bulletin ◽  
2003 ◽  
Vol 28 (6) ◽  
pp. 424-427 ◽  
Author(s):  
Agnès Aymonier ◽  
Eric Papon
Keyword(s):  
Automotive Industry ◽  
Ease Of Use ◽  
Large Strains ◽  
Structural Adhesives ◽  
Wide Range ◽  
Step Growth ◽  
Visible Irradiation ◽  
Step Growth Polymerization ◽  
Uv Visible ◽  
Activation Heat

AbstractSoft reactive adhesives (SRAs) are polymer-based materials (e.g., polyurethanes, polysiloxanes, polydienes) designed to be further vulcanized or slightly cross-linked through external activation (heat, moisture, oxygen, UV–visible irradiation, etc.), either at the time of their application or within a subsequent predefined period. They are used mainly as mastics, or sealing compounds, in a wide range of industrial and commercial fields such as construction, footwear, and the automotive industry. Generally deposited as thick films, SRAs behave as structural adhesives; their low elastic moduli accommodate large strains between the bonded parts without incurring permanent damage. Other outstanding attributes of SRAs are their resistance to solvents, their ability to withstand aggressive environments, and their ease of use. This article discusses examples of SRAs and, more specifically, shows how the cross-linking chemistry, mainly through step-growth polymerization, provides their primary advantages.

Ultrasonographic Applications in the Thorax

2021 ◽  
Vol 18 ◽  
Author(s):  
Mehmet Zeki Gunluoglu ◽  
Tugrul Ormeci ◽  
Selva Sen
Keyword(s):  
Emergency Department ◽  
Intensive Care ◽  
Pleural Effusion ◽  
Respiratory System ◽  
Ease Of Use ◽  
Endobronchial Ultrasound ◽  
Access Price ◽  
Wide Range ◽  
Diagnostic Sensitivity And Specificity ◽  
Fast Access

Abstract: Rapid developments and increasing technological knowledge have changed perspectives on ultrasonography. Previously, ultrasonography was used to evaluate chest wall pathologies, to distinguish between pleural effusion and consolidation, to evacuate pleural effusion, or to evaluate diaphragm movement. Today, it is also used in a wide range of pleural and parenchymal diseases. Ultrasonography is not just used in the emergency department and the intensive care units. It is also utilized in many clinical branches dealing with the respiratory system—due to its ease of use, fast access, price advantage, non-radiation exposure, higher diagnostic sensitivity, and specificity in many clinical situations—and has become a part of the examination. In this review, we have assessed not just transthoracic ultrasonography but also more focal and targeted sonographic applications, such as the endobronchial ultrasound and esophageal ultrasound.

scholarly journals Effect of Postoperative Diclofenac on Anastomotic Strength and Histologic Healing in Rabbit Small Intestine

2015 ◽  
Vol 100 (11-12) ◽  
pp. 1435-1442
Author(s):  
Sebastian S Le Grevès ◽  
Petter Lysberg Bremseth ◽  
Matteo Biagini ◽  
Rene Holst ◽  
Niels Qvist
Keyword(s):  
Placebo Group ◽  
Anastomotic Leakage ◽  
Breaking Strength ◽  
Gastrointestinal Surgery ◽  
Isotonic Saline ◽  
Anastomotic Healing ◽  
Postoperative Treatment ◽  
White Female ◽  
Negative Effects ◽  
Negative Effect

In this experimental study, we investigated the effects of a 5-day postoperative treatment with the nonsteroidal anti-inflammatory drug (NSAID) diclofenac on anastomotic healing in rabbits. NSAIDs are widely used analgesics in today's “fast-track surgery,” raising concerns about their potential negative effects on healing in humans. A total of 33 New Zealand White female rabbits underwent laparotomy and 2 separate end-to-end anastomoses of the ileum.. The animals were randomized to receive subcutaneous diclofenac 4 mg/kg/d (17 experimental rabbits) or subcutaneous isotonic saline 0.1 mL/kg/d (16 control rabbits) postoperatively. On the fifth postoperative day, the animals were humanely killed, and anastomotic leakage, anastomotic breaking strength, and histopathologic changes were evaluated. Breaking strength in the diclofenac group was 21% lower than in the placebo group (P = 0.027). Anastomotic leakage was found in 4 rabbits in the diclofenac group (26.7%). The rabbits treated with diclofenac demonstrated a 16% lower collagen deposition compared with the placebo group (P = 0.008). In our study, postoperative treatment with diclofenac had a negative effect on the anastomotic healing and strength in the ileum of rabbits. Caution should be taken in the use of diclofenac after gastrointestinal surgery.

scholarly journals Violência doméstica contra a mulher gestante

2017 ◽  
Vol 11 (12) ◽  
pp. 4999
Author(s):  
Naiany Monise Gomes Ramalho ◽  
Josefa Danielma Lopes Ferreira ◽  
Carla Lidiane Jácome de Lima ◽  
Thalys Maynnard Costa Ferreira ◽  
Sayonara Lays Umbelino Souto ◽  
...  
Keyword(s):  
Risk Factors ◽  
Domestic Violence ◽  
Pregnant Women ◽  
Violence Against Women ◽  
Exclusion Criteria ◽  
Scientific Publications ◽  
Cross Sectional ◽  
Wide Range ◽  
Factores De Riesgo ◽  
Violencia Domestica

RESUMOObjetivo: analisar as publicações científicas sobre a violência doméstica contra a mulher gestante. Método: revisão integrativa, com buscas nas bases de dados MEDLINE, SCOPUS, LILACS e BDENF, usando os descritores em português e inglês violência doméstica, mulher grávida e Enfermagem. Foram identificados 536 artigos. Após critérios de inclusão e exclusão, obtiveram-se 16 estudos que compuseram a amostra. A apresentação dos resultados e a discussão final foram feitas de forma descritiva, além de estatística simples por porcentagem e apresentados sob a forma de figuras. Resultados: dos estudos incluídos na revisão, 18,8% foram publicados em 2007. Quanto ao tipo de estudo, 56,3% foram estudos de corte transversal. Os tipos de violência mais retratados foram o sexual, o físico e o psicológico. Todos os estudos relatavam os fatores de risco para a violência contra a mulher gestante. Conclusão: analisando os estudos, foi possível identificar uma ampla gama de fatores de risco encontrados na literatura e a falta de registros sobre a assistência de saúde à mulher grávida em situação de violência. Descritores: Enfermagem; Violência Doméstica; Mulher Grávida; Violência Contra a Mulher; Cuidados De Enfermagem; Fatores de Risco.ABSTRACTObjective: to analyze the scientific publications on domestic violence against pregnant women. Method: integrative review, with searches in the MEDLINE, SCOPUS, LILACS and BDENF databases, using the descriptors in Portuguese and English, domestic violence, pregnant women and Nursing. A total of 536 articles were identified. After inclusion and exclusion criteria, we obtained 16 studies that composed the sample. The presentation of the results and final discussion was done in a descriptive way, in addition to simple statistics by percentage and presented in the form of figures. Results: of the studies included in the review, 18.8% were published in 2007. Regarding the type of study, 56.3% were cross-sectional studies. The types of violence most portrayed were sexual, physical and psychological. All studies reported the risk factors for violence against pregnant women. Conclusion: analyzing the studies, it was possible to identify a wide range of risk factors found in the literature and the lack of records on health care for pregnant women in situations of violence. Descriptors: Nursing; Domestic Violence; Pregnant Woman; Violence Against Women; Nursing Care; Risk Factors.RESUMENObjetivo: analizar las publicaciones científicas sobre la violencia doméstica contra la mujer gestante. Método: revisión integrativa, con búsquedas en las bases de datos MEDLINE, SCOPUS, LILACS y BDENF, usando los descriptores en portugués e inglés violencia doméstica, mujer embarazada y Enfermería. Se identificaron 536 artículos. Después de criterios de inclusión y exclusión, se obtuvieron 16 estudios que compusieron la muestra. La presentación de los resultados y la discusión final fueron hechas de forma descriptiva, además de estadística simple por porcentaje y presentados bajo la forma de figuras. Resultados: de los estudios incluidos en la revisión, el 18,8% fueron publicados en 2007. En cuanto al tipo de estudio, el 56,3%, fueron estudios de corte transversal. Los tipos de violencia más retratados fueron el sexual, el físico y el psicológico. Todos los estudios relataban los factores de riesgo para la violencia contra la mujer embarazada. Conclusión: analizando los estudios, fue posible identificar una amplia gama de factores de riesgo encontrados en la literatura y la falta de registros sobre la asistencia de salud a la mujer embarazada en situación de violencia. Descriptores: Enfermería; La Violencia Doméstica; Mujer Embarazada; Violencia Contra la Mujer; Atención de Enfermería; Factores de Riesgo.

scholarly journals Identification and Reporting of Patient and Public Partner Authorship on Knowledge Syntheses: Rapid Review (Preprint)

2021 ◽  
Author(s):  
Ursula Ellis ◽  
Vanessa Kitchin ◽  
Mathew Vis-Dunbar
Keyword(s):  
Public Involvement ◽  
Geographic Location ◽  
Patient And Public Involvement ◽  
Advisory Council ◽  
Rapid Review ◽  
Medline Search ◽  
Ovid Medline ◽  
Cochrane Database ◽  
Wide Range ◽  
Scoping Reviews

BACKGROUND Patient and public involvement (PPI) in health research is an area of growing interest. Several studies have examined the use and impact of PPI in knowledge syntheses (systematic, scoping, and related reviews); however, few studies have focused specifically on the patient or public coauthorship of such reviews. OBJECTIVE This study seeks to identify published systematic and scoping reviews coauthored by patient or public partners and examine the characteristics of these coauthored reviews, such as which journals publish them, geographic location of research teams, and terms used to describe patient or public partner authors in affiliations, abstracts, or article text. METHODS We searched CAB Direct, CINAHL, Cochrane Database of Systematic Reviews (Ovid), Embase (Ovid), MEDLINE (Ovid), and PsycInfo from 2011 to May 2019, with a supplementary search of several PPI-focused databases. We refined the Ovid MEDLINE search by examining frequently used words and phrases in relevant search results and searched Ovid MEDLINE using the modified search strategy in June 2020. RESULTS We screened 13,998 results and found 37 studies that met our inclusion criteria. In line with other PPI research, we found that a wide range of terms were used for patient and public authors in author affiliations. In some cases, partners were easy to identify with titles such as patient, caregiver or consumer representative, patient partner, expert by experience, citizen researcher, or public contributor. In 11% (n=4) of studies, they were identified as members of a panel or advisory council. In 27% (n=10) of articles, it was either impossible or difficult to tell whether an author was a partner solely from the affiliation, and confirmation was found elsewhere in the article. We also investigated where in the reviews the partner coauthors’ roles were described, and when possible, what their specific roles were. Often, there was little or no information about which review tasks the partner coauthors contributed to. Furthermore, only 14% (5/37) of reviews mentioned patient or public involvement as authors in the abstract; involvement was often only indicated in the author affiliation field or in the review text (most often in the methods or contributions section). CONCLUSIONS Our findings add to the evidence that searching for coproduced research is difficult because of the diversity of terms used to describe patient and public partners, and the lack of consistent, detailed reporting about PPI. For better discoverability, we recommend ensuring that patient and public authorships are indicated in commonly searched database fields. When patient and public-authored research is easier to find, its impact will be easier to measure.

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