Effect of Vitex agnus-castus on Depression of Postmenopausal Women: A Randomized Clinical Trial

Background: During menopause, women undergo biological, social, and psychological changes and are sensitive to stressors, especially anxiety and depression. Decreased estrogen in postmenopausal women causes mood swings, especially depression and anxiety. Objectives: We aimed to determine the effect of the Vitex agnus-castus extract on depression in postmenopausal women referring to a bone density measurement center in Shiraz. Methods: In a randomized controlled tria1, 60 postmenopausal women were randomly divided into an intervention group and a control group. In the intervention group, the research units were assigned to two groups of Vitex agnus-castus tablets and placebo, using random permuted blocks with a block size from one to six for each eligible case. After three months, depression was evaluated by the Edinburg Postnatal Depression Scale (EPDS) in both groups. Then, the results were analyzed using the independent t-test for quantitative variables. The obtained data were analyzed by a statistician using SPSS21. Results: Based on the results, the two groups were homogeneous in terms of the level of education, occupation, and housing, and a significant decrease was observed in the mean depression score in the Agnugolgroup (P < 0.001). Conclusions: Because depression increases during menopause, it is recommended that it should be used as a supplement during menopause.

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The effect of ketamine on preventing postpartum depression

Journal of Medicine and Life ◽

10.25122/jml-2020-0116 ◽

2021 ◽

Vol 14 (1) ◽

pp. 87-92

Author(s):

Mina Alipoor ◽

◽

Marzeyeh Loripoor ◽

Majid Kazemi ◽

Farshid Farahbakhsh ◽

...

Keyword(s):

Body Weight ◽

Postpartum Depression ◽

Repeated Measures ◽

Intervention Group ◽

Depression Scale ◽

Caesarian Section ◽

Depression Score ◽

Control Group ◽

Chi Square ◽

Double Blind

Postpartum depression is a common disabling psychosocial disorder that could have adverse effects on the life of the mother, infant, and family. The present study was conducted to evaluate the effect of ketamine on preventing postpartum depression in women undergoing caesarian sections considering the relatively known positive effect of ketamine on major depression. The present double-blind, randomized clinical trial was conducted on 134 women undergoing scheduled caesarian sections. Participants were randomly allocated into two groups of control and intervention. To induce anesthesia, 1–2 mg/kg of body weight of Nesdonal and 0.5 mg/kg of body weight of ketamine were used in the intervention group, while only 3–5 mg/kg of body weight Nesdonal was administered in the control group. Data were gathered using the Edinburgh Postnatal Depression Scale (EPDS) in three stages: before the caesarian section and two and four weeks after the caesarian section. Data were analyzed using variance analysis with repeated measures and the Chi-square test. Results of the present study showed that the mean (± standard deviation) of the depression score in the intervention and control groups were 13.78±3.87 and 13.79±4.78(p = 0.98) before the caesarian section, 11.82±3.41 and 14.34±4.29 (p < 0.001) two weeks after and 10.84±3.48 and 13.09±3.79 (p = 0.001) four weeks after the caesarian section, respectively. Using ketamine in the induction of general anesthesia could be effective in preventing postpartum depression. However, further studies are required to strengthen these findings.

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A Randomized Clinical Trial of the Effect of Zinc Supplement on Depression and Anxiety in the Elderly

The Open Public Health Journal ◽

10.2174/1874944502114010537 ◽

2021 ◽

Vol 14 (1) ◽

pp. 537-544

Author(s):

Abolfazl Afzali ◽

Zarichehr Vakili ◽

Shahrbanoo Goli ◽

Hossein Bagheri ◽

Seyedmohammad Mirhosseini ◽

...

Keyword(s):

Clinical Trial ◽

Randomized Clinical Trial ◽

Zinc Supplementation ◽

Statistical Tests ◽

Intervention Group ◽

Depression Scale ◽

The Elderly ◽

Control Group ◽

Depression And Anxiety ◽

Zinc Supplements

Background: Anxiety and depression in the elderly are considered important mental disorders. Objective: This study was designed to determine the effect of zinc Supplementation on depression and anxiety in the elderly. Methods: This study was a parallel randomized clinical trial. A total of 150 elderly aged 60 years and older were allocated into intervention and control groups by using the quadruple blocking method. The elderly in the intervention group received a daily dose of 30 mg zinc supplementation pill for 70 days and the elderly in the control group did not receive this supplement. Depression and anxiety in the elderly were measured using the Geriatric Depression Scale and the Beck Anxiety Inventory, respectively. A significance level of 0.05 was considered for all statistical tests. Results: After the intervention, the mean scores of depression and anxiety in the elderly were significantly decreased in the intervention group, as compared with the control group. Moreover, after the intervention, the serum zinc level in the elderly was significantly increased in the intervention group, as compared with the control group (P<0.05). Conclusion: The use of zinc supplements improved depression and anxiety in the elderly. Therefore, it is recommended to use zinc supplements as a new therapeutic strategy for the prevention and treatment of depression and anxiety in the elderly. Registration No: This research was registered in the Iranian clinical trial system with code IRCT2017071635110N1.

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Listening to Javanese Gamelan Can Reduce Depression Score in Institutionalized Elderly

Jurnal Keperawatan Soedirman ◽

10.20884/1.jks.2020.15.1.1155 ◽

2020 ◽

Vol 15 (1) ◽

Author(s):

Wahyu Rochdiat M ◽

Elfiana Dewi Lestari

Keyword(s):

Nursing Home ◽

Intervention Group ◽

Depression Scale ◽

Sampling Technique ◽

Depression Score ◽

Wilcoxon Test ◽

Control Group ◽

P Value ◽

Institutionalized Elderly ◽

The Impact

ABSTRACTElderlies who lives in nursing home conceive a high risk of experiencing depression. Music that is usually heard by the elderly in Java Province is Javanese gamelan and there was a few of research that examined its effect on the elderlies depression. The purpose of this study was to assess the impact of listening to Javanese gamelan on the depression score of institutionalized elderly. This research used a quasi-experimental design with a pretest-posttest control group approach. The researchers screened 88 elderlies who live in one of nursing home in Yogyakarta with GDS (Geriatric Depression Scale), which acquired 49 depressed elderlies. A purposive sampling technique (criteria: Javanese, not experiencing the hearing loss, cooperative, and not in an isolation room) conduced 26 elderlies as samples. The subjects were divided into two groups with same proportion of ages in each group. Wilcoxon test indicated that there was a decreasing of the depression score in the intervention group (p-value 0.000). The depression score in the control group increased from 7.46 to 9.46. Javanese gamelan is effective in reducing the depression score in institutionalized elderlies.Keywords: Depression, elderly, Javanese gamelan

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The effect bibliotheraphy on depression and anxiety level of breast cancer patient at Arifin Achmad Regional General Hospital of Riau Province

Jurnal Kesehatan Komunitas ◽

10.25311/keskom.vol5.iss3.466 ◽

2019 ◽

Vol 5 (3) ◽

pp. 248-253

Author(s):

Bayu saputra ◽

Yani Sofiani ◽

Diana Irawati

Keyword(s):

Breast Cancer ◽

Cancer Patient ◽

Breast Cancer Patient ◽

Intervention Group ◽

Depression Scale ◽

Psychological Problem ◽

Future Research ◽

Control Group ◽

Depression And Anxiety ◽

Control Group Design

Patient with breast cancer who get chemotheraphy has an side effect, one of this effect is psychological problem. The psychological problem among breast cancer patient is about depression and anxiety. The implementation of biblioteraphy has a positive effect on psychological condition. The aim of this research was to identify the effect biblioteraphy method on the level of depression and anxiety of breast cancer patient. The method was used quasy experimental pretest-postest with intervention control group design. The sampel was 32 respondents using purposive sampling technique wich divided into 2 groups, the intervention group received biblioteraphy story telling method and pray of Prophet Ayyub Alaihisalam while the control group without intervention.The evaluation of psychological aspect depression and anxiety used Hospital Anxiety Depression Scale (HADS) in bahasa. The analysis of depression and anxiety changes measured using independent t-test. The result: There was a significant relationship between level of depression and anxiety in pre and post on respondents who received intervention and without intervention. Conclusion: the applying of intervention of biblioteraphy method with frequency as much as 5 time and maximum in 45 minutes proved in lowering level of depression and anxiety. It is suggested for applying bibliotheraphy when giving nursing care of breast cancer patient. The future research should investigate other aspect such as education and environment against level of depression and anxiety.

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Comparison of the Effects of Fenugreek Vaginal Cream and Ultra Low- Dose Estrogen on Atrophic Vaginitis

Current Drug Delivery ◽

10.2174/1567201817666200708112655 ◽

2020 ◽

Vol 17 (9) ◽

pp. 815-822

Author(s):

Maryam Safary ◽

Sevil Hakimi ◽

Noushin Mobaraki-Asl ◽

Paria Amiri ◽

Habib Tvassoli ◽

...

Keyword(s):

Postmenopausal Women ◽

Low Dose ◽

Intervention Group ◽

Clinical Signs ◽

Control Group ◽

Conjugated Estrogens ◽

Atrophic Vaginitis ◽

Vaginal Cream ◽

Intergroup Comparison ◽

Significant Difference

Introduction: Atrophic vaginitis is a common problem in postmenopausal women and results from decreased levels of blood estrogen. It is associated with symptoms of itching, burning, dyspareunia, and postmenopausal bleeding. The present study evaluated the effects of fenugreek extract on atrophic vaginitis. Materials and Methods: This randomized controlled clinical trial was performed on 60 postmenopausal women in Ardabil, Iran, in 2018. The participants were selected using block randomization with the allocation ratio 1:1. Those in the intervention group received 0.5g (the applicator filled to the half-full mark) fenugreek vaginal cream 5% twice a week for 12 weeks. The control group received conjugated estrogens vaginal cream at the dose of 0.625 mg (the applicator filled to the half-full mark) containing 0.3 mg of conjugated estrogens. Atrophic vaginitis was evaluated before and after the treatment through clinical examination, clinical signs, and measurement of Vaginal Maturation Index (VMI). Findings: After the 12-week intervention and modification of the baseline score, the mean (standard error) score for atrophic vaginitis signs was 3.100 (1.43-4.75). This difference was statistically significant in intragroup comparison and in favor of the control group in intergroup comparison (p=0.001). VMI was less than 49% in 86.7% and 46.7% of the participants in the intervention and control groups, respectively. This was a significant difference in favor of the control group (p=0.001). Conclusion: The results of this study showed that total fenugreek extract could be effective in treating signs of atrophic vaginitis, but it was not as effective as ultra-low-dose estrogen.

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The effectiveness of emotional freedom techniques (EFT) on depression of postmenopausal women: a randomized controlled trial

Journal of Complementary and Integrative Medicine ◽

10.1515/jcim-2020-0245 ◽

2021 ◽

Vol 0 (0) ◽

Author(s):

Asieh Mehdipour ◽

Parvin Abedi ◽

Somayeh Ansari ◽

Maryam Dastoorpoor

Keyword(s):

Randomized Controlled Trial ◽

Postmenopausal Women ◽

Controlled Trial ◽

Intervention Group ◽

Control Group ◽

Randomized Controlled ◽

Moderate Depression ◽

Before And After ◽

The Mean ◽

And Control

Abstract Objectives Postmenopausal women are at greater risk of depression. Depression may negatively affect the quality of life of women. An emotional freedom technique (EFT) is an evidence-based therapy combining cognitive and exposure components with acupressure. This study aimed to evaluate the effect of EFT on depression in postmenopausal women. Methods This was a randomized controlled trial in which 88 women with mild to moderate depression recruited from a menopausal clinic in Ahvaz, Iran, and randomly assigned into two groups of EFT (n=44) and control for sham therapy (n=44). Women in the EFT group received two sessions of training and asked to continue EFT for 8 weeks, one time per day. The Beck Depression Inventory (BDI2) completed by women before and after the intervention. The control group received training on sham acupressure points similar to the intervention group. Data collected using a demographic and BDI2. Women requested to complete the BDI2 before and after the intervention. The independent t-test, chi-square, and ANCOVA were used to analyze data. Results The mean depression score in the intervention group reduced from 20.93 ± 4.6 to 10.96 ± 4.38 in comparison to the control group that reduced from 19.18 ± 2.79 to 17.01 ± 6.05 after intervention (p=0.001). After the 8 week intervention, the frequency of moderate depression decreased from 56.8 to 9.35% in the intervention and from 50 to 29.5% in the control group. In total, 63.4 and 34.15% in the intervention and control groups were free of depression respectively after the intervention (p<0.001). Conclusions The results of this study showed that using EFT for 8 weeks could significantly reduce the mean score of depression in postmenopausal women. Using this method in public health centers for postmenopausal women is recommended.

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The Effect of Dialectic Behavioral Counseling on Depression, Anxiety, and Postpartum Hematocrit Level

Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics ◽

10.1055/s-0041-1728780 ◽

2021 ◽

Vol 43 (04) ◽

pp. 275-282

Author(s):

Nasrin Pour Amiri ◽

Atefeh Ahmadi ◽

Firoozeh Mirzaee ◽

Moghadameh Mirzai ◽

Nader Shahrokhi

Keyword(s):

Postpartum Depression ◽

Behavioral Therapy ◽

Intervention Group ◽

Anxiety Symptoms ◽

Control Group ◽

P Value ◽

Depression And Anxiety ◽

Hematocrit Level ◽

Negative Experience ◽

Behavioral Counseling

Abstract Objective Childbirth is a biological, psychological, and sociological event that can be a positive or negative experience, and, without support, this period may be potentially damaging. Parturition may distort maternal emotions and lead to short- or long-term disorders such as postpartum depression and anxiety. The present research aims to study the effects of dialectic behavioral therapy-based counseling on depression, anxiety symptoms, and postpartum hematocrit level. Methods The current research is a clinical trial study, and the sample was selected using parturients who were referred to the Health General Center with a diagnosis of postpartum depression and anxiety. The sample size consisted of 116 subjects who agreed to participate in the study. The patients in intervention group underwent group dialectic behavioral counseling (10 sessions/one session per week) and the control group did not receive any type of intervention. The patients were assessed in the first and last sessions as well as 2 months after the end of the sessions, using the Beck depression scale and Spielberg anxiety scale as well as the results of hematocrit tests. Data were analyzed using the IBM SPSS Statistics for Windows, Version 21.0 (IBM Corp., Armonk, NY, USA) Results The results implied the effectiveness of dialectic behavioral therapy on reduction of the depression score, anxiety symptoms (p-value ≤ 0.0001), and hematocrit level (p-value = 0.04). The participants' depression, anxiety, and hematocrit levels decreased in the experiment group compared to the control group, and this decrease has remained until the 2-month follow-up. Conclusion It seems that dialectic behavioral counseling reduces the levels of postpartum depression, anxiety, and hematocrits.

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Effect of Communication Skills Training Program for Oncologists Based on Patient Preferences for Communication When Receiving Bad News: A Randomized Controlled Trial

Journal of Clinical Oncology ◽

10.1200/jco.2013.51.2756 ◽

2014 ◽

Vol 32 (20) ◽

pp. 2166-2172 ◽

Cited By ~ 91

Author(s):

Maiko Fujimori ◽

Yuki Shirai ◽

Mariko Asai ◽

Kaoru Kubota ◽

Noriyuki Katsumata ◽

...

Keyword(s):

Communication Skills ◽

Patient Preferences ◽

Controlled Trial ◽

Intervention Group ◽

Depression Scale ◽

Skills Training ◽

Control Group ◽

Communication Skills Training ◽

Communication Performance

Purpose The aim of this study was to identify the effects of a communication skills training (CST) program for oncologists, developed based on patient preferences regarding oncologists' communication. Participants and Methods Thirty oncologists were randomly assigned to either an intervention group (IG; 2-day CST workshop) or control group (CG). Participants were assessed on their communication performance during simulated consultation and their confidence in communicating with patients at baseline and follow-up. A total of 1,192 patients (response rate, 84.6%) who had consultations with the participating oncologists at baseline and/or follow-up were assessed regarding their distress using the Hospital Anxiety and Depression Scale, satisfaction with the consultation, and trust in their oncologist after the consultation. Results At the follow-up survey, the performance scores of the IG had improved significantly, in terms of their emotional support (P = .011), setting up a supportive environment (P = .002), and ability to deliver information (P = .001), compared with those of the CG. Oncologists in the IG were rated higher at follow-up than those in the CG in terms of their confidence in themselves (P = .001). Patients who met with oncologists after they had undergone the CST were significantly less depressed than those who met with oncologists in the CG (P = .027). However, the CST program did not affect patient satisfaction with oncologists' style of communication. Conclusion A CST program based on patient preferences is effective for both oncologists and patients with cancer. Oncologists should consider CST as an approach to enhancing their communication skills.

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THE EFFECT OF DHIKR ON ANXIETY AND DEPRESSION LEVEL IN HEMODIALYSIS PATIENTS AT PURWOKERTO ISLAMIC HOSPITAL

International Journal of Islamic Medicine ◽

10.37275/ijim.v2i1.17 ◽

2021 ◽

Vol 2 (1) ◽

pp. 15-25

Author(s):

Muhammad Anggun ◽

Titik Kusumawinakhyu ◽

Irma Finurina Mustikawati ◽

Wiharto Wiharto

Keyword(s):

Intervention Group ◽

Depression Scale ◽

Sampling Technique ◽

Hemodialysis Patients ◽

Anxiety And Depression ◽

Control Group ◽

Control Group Design ◽

Hemodialysis Unit ◽

Before And After ◽

The Mean

Hemodialysis is a routinely performed therapy on chronic kidney patients, leading to psychological problems among subjects who undergo hemodialysis, such as anxiety and depression. One of the efforts to overcome anxiety and depression is with the dhikr intervention. Dhikr presents hearts to remember and be obedient to Allah followed by the words and actions in various conditions. Discover dhikr's influence on the level of anxiety and depression in patients on hemodialysis in Purwokerto Islamic Hospital. It was a quantitative study using quasi experiment with a non-quivalent control group design. The number of samples was 12 subjects consisting of 6 subjects in the control group and six subjects in the intervention group with the purposive sampling technique. Instruments were used to measure anxiety and depression are the HADS ( Hospital Anxiety and Depression Scale ) before and after dhikr intervention as much as 12 times. Research is carried out in Hemodialysis Unit of Purwokerto Islamic Hospital. Test statistics on research are used paired t-test and independent t-tests. This study showed a decrease in the mean level of anxiety from 5, 83 to 1.67 in the experimental group ( p = 0.003). The mean level of depression experienced a decline of 9, 67 becomes 4.67 on a group experiment ( p = 0.003). Dhikr reduces the level of anxiety and depression in hemodialysis patients at the Purwokerto Islamic Hospital.

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Nursing consultation protocol for patients after myocardial revascularization: influence on anxiety and depression

Revista Latino-Americana de Enfermagem ◽

10.1590/s0104-11692010000300006 ◽

2010 ◽

Vol 18 (3) ◽

pp. 331-338 ◽

Cited By ~ 2

Author(s):

Francisca Elisângela Teixeira Lima ◽

Thelma Leite de Araújo ◽

Edilma Casimiro Gomes Serafim ◽

Ires Lopes Custódio

Keyword(s):

Clinical Trial ◽

Outpatient Clinic ◽

Public Hospital ◽

Intervention Group ◽

Myocardial Revascularization ◽

Depression Scale ◽

Lower Percentage ◽

Anxiety And Depression ◽

Control Group ◽

Hospital Anxiety

The objective was to evaluate the influence of the Nursing Consultation Protocol in aspects of anxiety and depression in patients after myocardial revascularization using the Hospital Anxiety and Depression scale (HAD). A randomized clinical trial developed in the outpatient clinic of a public hospital in Fortaleza-Ceará. One hundred and forty six patients, who underwent myocardial revascularization, composed the population, providing the sample of 39 patients in the control group (CG) and 39 in the intervention group (IG). The results were presented in tables. Anxiety had a mean of 5.41 in the CG and a median of 5 and a mean in the IG of 5.21 and a median of 4. Depression predominated in the CG, with a mean 4.82 and a median of 4, while the IG had a mean of 3.79 and a median of 3. It was found that people monitored in accordance with the Nursing Consultation Protocol had a lower percentage of anxiety and depression after six months.

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