scholarly journals Gambaran Darah Tepi, Rasio Neutrofil-Limfosit, dan Rasio Trombosit-Limfosit pada Pasien Tuberkulosis Paru dengan Depresi

2019 ◽  
Vol 6 (2) ◽  
pp. 82
Author(s):  
Hamzah Shatri ◽  
Reinaldo Alexander ◽  
Rudi Putranto ◽  
Ikhwan Rinaldi ◽  
Cleopas Martin Rumende
Keyword(s):  
Pulmonary Tuberculosis ◽  
Multidrug Resistant ◽  
Blood Cell Count ◽  
Statistical Manual ◽  
Pulmonary Tb ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Diagnostic And Statistical Manual ◽  
Dsm V ◽  
Severity Of Depression

Pendahuluan.  Pasien dengan tuberkulosis (TB) paru memiliki peningkatan risiko untuk mengalami depresi sampai 1,53 kali dari sebuah studi kohort besar. Studi – studi menemukan adanya peningkatan rasio neutrofil – limfosit (RNL) pada berbagai gangguan mood termasuk depresi, juga rasio trombosit – limfosit (RTL) terkait dengan depresi berat yang disertai dengan gejala psikotik. Penelitian ini dilakukan untuk mengetahui karakteristik gambaran darah tepi, RNL, dan RTL pada pasien TB paru yang mengalami depresi.Metode. Studi dengan desain potong lintang dilakukan terhadap 106 pasien TB paru tidak resisten obat yang berobat jalan di poliklinik paru RS Cipto Mangunkusumo, Jakarta dari bulan Agustus hingga Oktober 2018. Diagnosis depresi ditegakkan dengan wawancara menurut kriteria diagnosis dari Diagnostic and Statistical Manual of Mental Disorder-V (DSM-V) dan derajat depresi ditentukan menggunakan kuesioner Beck Depression Inventory-II (BDI-II). Pemeriksaan laboratorium dilakukan untuk mendapatkan hasil darah perifer lengkap, RNL, dan RTL. Uji statistik parametrik digunakan untuk variabel-variabel numerik dengan sebaran merata, sementara uji nonparametrik digunakan bila sebaran tidak merata.Hasil. Dari 106 pasien TB paru tidak resisten obat yang menjadi subjek penelitian, didapatkan proporsi depresi sebesar 32%. Didapatkan nilai leukosit lebih rendah pada pasien TB paru dengan depresi (p=0,024), dan juga nilai limfosit absolut yang lebih rendah pada pasien TB paru dengan depresi (p=0,004) bila dibandingkan dengan subjek tanpa depresi. Rasio neutrofil – limfosit (RNL) dan RTL tidak berhubungan signifikan secara statistik (p>0,05) dengan beratnya derajat depresi. Simpulan. Nilai hitung leukosit dan limfosit pada pasien TB paru dengan depresi lebih rendah dibandingkan pasien tanpa depresi. Nilai RNL dan RTL pada pasien depresi dengan TB paru lebih tinggi walaupun tidak signifikan secara statistik. Kata Kunci: Depresi, Gambaran darah tepi, Rasio neutrofil – limfosit, Rasio trombosit – limfosit, Tuberkulosis paruPeripheral Blood Count Characteristics, Neutrophil-Lymphocyte Ratio, and Platelet-Lymphocyte Ratio Pulmonary Tuberculosis Patients with DepressionIntroduction. Patients with pulmonary tuberculosis (TB) had an increased risk for depression up to 1.53 times from a large cohort study. Studies have found an increase in the neutrophil - lymphocyte ratio (NLR) in various mood disorders including depression, also the value of the platelet-lymphocyte ratio (PLR) associated with major depression accompanied by psychotic symptoms. This study aimed to describe the peripheral blood characteristics, NLR,  and PLR in pulmonary TB patients with depression.  Methods. A cross-sectional study of 106 non-multidrug-resistant pulmonary TB patients was done at outpatient department of Cipto Mangunkusumo General Hospital, Jakarta from August to October 2018. The diagnosis of depression was made by interview according to Diagnostic and Statistical Manual of Mental Disorder-V (DSM-V) criteria, and severity of depression is determined using Beck Depression Inventory-II (BDI-II). The laboratory tests were done to obtain complete peripheral blood results, NLR, and TLR. Parametric test was used for numeric variables with even distribution, and nonparametric test for variables with uneven distribution.Results. From 106 patients with non-multidrug-resistant pulmonary TB, the proportion of depression was 32%. White blood cell count (p=0.024), and absolute lymphocte count (p=0.004) is lower in depressed TB patients compared to nondepressed TB patients. There were no significant relationship between NLR and TLR and the severity of depression in depressed pulmonary TB patients (p>0.05). Conclusion. White blood cell count and absolute lymphocyte count are lower in depressed pulmonary TB patients. Meanwhile, RNL and PLR are higher in depressed pulmonary TB patients eventhough not statistically significant.

Validación de la escala de sintomas somáticos (SSS-8) en pacientes de una zona rural en Ecuador

2018 ◽  
Vol 3 (2) ◽  
Author(s):  
Mercy García ◽  
Ernestina Tamami ◽  
Giovanni Rojas-Velasco ◽  
Carolina Posso ◽  
Galo Sánchez del Hierro ◽  
...  
Keyword(s):  
Mental Disorders ◽  
Somatic Symptom ◽  
Symptom Scale ◽  
Statistical Manual ◽  
Diagnostic And Statistical Manual ◽  
Calidad De Vida ◽  
Dsm V ◽  
Scale 8

Introducción.- Los síntomas somáticos causan malestar y afectan la calidad de  vida de los pacientes, incrementando la frecuencia del uso de los servicios de salud. En Ecuador no existe un instrumento validado que evalúe somatización. La escala Somatic Symtom Scale-8 (SSS-8), es un instrumento usado como medida de referencia en the Diagnostic and Statistical Manual of Mental Disorders(DSM-V), para evaluar la carga de síntomas somáticos, validada en inglés y adaptada culturalmente a los idiomas alemán y japonés. Objetivos.- En esta investigación el propósito fue validar la escala “Somatic Symptom Scale-8” y determinar sus propiedades métricas. Métodos.- Investigación descriptiva y transversal en la que se realizó la validación de la herramienta clínica SSS-8 en 401 pacientes en la consulta externa del hospital Pedro Vicente Maldonado, desde mayo a julio de 2017. Para el análisis de datos se utilizaron los programas estadísticos SPSS versión 23, Latent gold y EpiDat 3.1. Resultados.- El grupo mayoritario fue de 30 a 47 años, con ligero predominio del sexo masculino (con 52,6%) sobre el femenino (47,4%). El SSS-8 mostró adecuadas propiedades métricas (alfa de Cronbach de 0,73). Mediante este análisis se obtuvo que, los pacientes que respondieron: algo, bastante o muchísimo en las dimensiones sentirse cansado, dolor de cabeza, dolor de brazos y dolor de espalda; tenían un 99% de probabilidades de presentar somatización. Conclusiones.- En este estudio, el SSS-8 demostró ser una herramienta útil para evaluar los síntomas somáticos en pacientes que acuden a consulta externa, ya que presentó buenas propiedades métricas: consistencia interna elevada, buena validez y una apropiada capacidad discriminativa.

scholarly journals Incidence of Delirium in Hospitalized Children with Cancer

2019 ◽  
Vol 4 (2) ◽  
Keyword(s):  
Cognitive Deficits ◽  
Pediatric Intensive Care ◽  
Limited Data ◽  
Statistical Manual ◽  
Diagnostic And Statistical Manual ◽  
Dsm V ◽  
Increased Risk ◽  
Short Period ◽  
Fluctuating Course

Delirium is defined in the Diagnostic and Statistical Manual of Mental Disorders: Fifth edition (DSM-V) as a “disturbance and change in attention and awareness from baseline that develops over a short period of time, with fluctuating course” [1]. Delirium occurs as a result of factors related to primary illness, the treatment of that illness, and stressful and disorientating environment of the hospital [2]. There are limited data to describe the incidence of delirium in children hospitalized with cancer [3]. Delirium occurs frequently in adults and is an independent predictor of mortality, increased length of stay, and increased risk for long-term cognitive deficits [3]. The prevalence of delirium in hospitalized adults ages 18-56 with cancer ranges from 18%-44% [4]. Most pediatric studies on delirium focus on the critically ill child in the pediatric intensive care unit (PICU). It is estimated that the incidence of delirium in this population is as high as 29% [5].

scholarly journals Validity Evidence of the Autistic Spectrum Disorder Behavior Scale

2021 ◽  
Vol 31 ◽  
Author(s):  
Camila Costa e Silva ◽  
Daniela Sacramento Zanini
Keyword(s):  
Autistic Spectrum Disorder ◽  
School Setting ◽  
Spectrum Disorder ◽  
Statistical Manual ◽  
Autistic Spectrum ◽  
Diagnostic And Statistical Manual ◽  
Dsm V ◽  
Behavior Scale ◽  
Pilot Sample ◽  
Abstract Screening

Abstract Screening instruments to detect symptoms of Autistic Spectrum Disorder (ASD) in the school setting are still needed. The study aimed to develop the Autistic Spectrum Disorder Behavior Scale (ASD-BS) according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V). The scale consists of 31 items, divided into communication; social interactions; restrictive, repetitive and ritual behaviors; and other indicators. The content validity included five expert judges and a pilot sample with 29 children between six and 12 years old. The results were shown to be adequate, all items reached agreement rates above 80% and Kappa of 0.84. Exploratory statistical analyzes showed Cronbach’s alpha equal to 0.78, sensitivity values ranging from 86 to 93% and specificity from 34 to 100%. ASD-BS is of quick implementation, uses the teacher as an informant and contributes to psychological assessment.

scholarly journals Ciberdependência: o papel das emoções na dependência de tecnologias digitais

2014 ◽  
Vol 7 (2) ◽  
pp. 148-161
Author(s):  
Jefferson Cabral Azevedo ◽  
Carlos Henrique Medeiros de Souza ◽  
Giovane do Nascimento
Keyword(s):  
Online Social Networks ◽  
Digital Technologies ◽  
Theoretical Research ◽  
Statistical Manual ◽  
Diagnostic And Statistical Manual ◽  
Internet Users ◽  
Dsm V ◽  
Compulsive Behaviors ◽  
Icd 10 ◽  
Statistical Results

RESUMO: O presente artigo visa utilizar conceitos de diversas áreas, proporcionando uma perspectiva multicausal e dialógica sobre os processos nosológicos de dependência de tecnologias digitais e as influências dos mecanismos motivacionais e emocionais sobre a aprendizagem de comportamentos compulsivos. A metodologia aplicada ao estudo é de caráter qualitativo e quantitativo, pois abrange tanto os fatores conceituais obtidos através de revisão bibliográfica como o desenvolvimento de resultados estatísticos através das análises dos resultados dos questionários aplicados no estudo em questão. Este breve constructo teórico busca evidenciar comportamentos patológicos na utilização das tecnologias digitais, principalmente dos usuários de internet e redes sociais digitais, utilizando os parâmetros da neuropsicologia, psicologia, psiquiatria e descrições presentes no DSM V, Manual Diagnóstico e Estatístico de Transtornos Mentais, e o CID 10, Compêndio Internacional de Doenças.PALAVRAS-CHAVE: dependência; tecnologias digitais; motivação; emoção; neuropsicologia; psicologia; psiquiatria.ABSTRACT: This research apply concepts from different areas, aiming to provide a multicausal and dialogical perspective on the nosologic process of dependence upon digital technologies and the influences of motivational and emotional mechanisms on learning compulsive behaviors. The data is approached both qualitatively and quantitatively, since its analysis covers the conceptual factors obtained from literature review and the development of statistical results obtained from the questionnaires applied. This brief theoretical research pursues to reveal pathological behaviors in the use of digital technologies, especially in the actions of internet users in online social networks. The parameters of neuropsychology, psychology, psychiatry are combined with descriptions contained in the DSM V, Diagnostic and Statistical Manual of Mental Disorders, and the ICD 10, International Compendium of Diseases.KEYWORDS: addiction, digital technologies; motivation; emotion; neuropsychology; psychology; psychiatry.

Problemi di psicoterapia

2010 ◽  
pp. 53-66
Keyword(s):  
Statistical Manual ◽  
Diagnostic And Statistical Manual ◽  
Dsm V ◽  
Classification Of Diseases ◽  
Icd 10 ◽  
Dsm Iv

Vengono presentati i principali sistemi di diagnosi psichiatrica, e precisamente le ultime edizioni del Diagnostic and Statistical Manual (DSM) dell'American Psychiatric Association (il DSM-III del 1980, il DSM-III-R del 1987, il DSM-IV del 1994, il DSM-IV-TR del 2000, e il DSM-V previsto per il 2013), la 10a edizione dell'International Classification of Diseases (ICD-10) proposta nel 1992 dall'Organizzazione Mondiale della Sanitŕ (OMS), e il Manuale Diagnostico Psicodinamico (PDM) prodotto dalla comunitŕ psicoanalitica internazionale nel 2006. A proposito dei DSM, vengono discussi alcuni problemi metodologici quali le dicotomie validitŕ/attendibilitŕ, categorie/dimensioni e politetico/monotetico, e anticipati alcuni dibattiti critici a proposito del futuro DSM-V. Infine, vengono discusse le seguenti problematiche: la psicopatologia "descrittiva" e "strutturale"; la diagnosi come "difesa" del terapeuta; l'aspetto scientifico e l'aspetto filosofico della diagnosi; i tentativi di "sospensione" del giudizio e dei nostri preconcetti; la dicotomia nomotetico-idiografico.

Developing the diagnostic and statistical manual V: what will “statistical” mean in DSM-V?

2007 ◽  
Vol 42 (4) ◽  
pp. 259-267 ◽  
Author(s):  
Helena Chmura Kraemer ◽  
Patrick E. Shrout ◽  
Maritza Rubio-Stipec
Keyword(s):  
Statistical Manual ◽  
Diagnostic And Statistical Manual ◽  
Dsm V

Evaluating the Usefulness of DSM in Diagnosing Mental Health Problems: A Review of the Literature

2016 ◽  
Vol 6 (1) ◽  
pp. 46-51
Author(s):  
Basak Baglama
Keyword(s):  
Mental Health ◽  
Mental Health Professionals ◽  
Mental Health Problems ◽  
Recent Literature ◽  
Health Problems ◽  
Analysis Method ◽  
Statistical Manual ◽  
Diagnostic And Statistical Manual ◽  
Dsm V

Understanding the needs of indivudals with mental disabilities is really important in terms of improving quality of life, intervention and promotion. Diagnostic and Statistical Manual of Mental Disorders (DSM-V) is widely used book for mental health professionals in order to make diagnosis. The present study discusses the usefulness of DSM in diagnosing mental health problems by emphasizing it’s advantages and criticisms. This study used document analysis method in order to provide an overview and discussion of recent literature regarding advantages and criticisms of DSM. Various issues have been discussed and conclusions have been made based on the literature review of this study. 

scholarly journals A unifying perspective on personality pathology across the life span: Developmental considerations for the fifth edition of theDiagnostic and Statistical Manual of Mental Disorders

2009 ◽  
Vol 21 (3) ◽  
pp. 687-713 ◽  
Author(s):  
Jennifer L. Tackett ◽  
Steve Balsis ◽  
Thomas F. Oltmanns ◽  
Robert F. Krueger
Keyword(s):  
Mental Disorders ◽  
Life Span ◽  
Later Life ◽  
Personality Pathology ◽  
Statistical Manual ◽  
Developmental Issues ◽  
Diagnostic And Statistical Manual ◽  
Dsm V ◽  
Dimensional Models ◽  
Middle Aged Adult

AbstractProposed changes in the fifth edition of theDiagnostic and Statistical Manual of Mental Disorders(DSM-V) include replacing current personality disorder (PD) categories on Axis II with a taxonomy of dimensional maladaptive personality traits. Most of the work on dimensional models of personality pathology, and on personality disorders per se, has been conducted on young and middle-aged adult populations. Numerous questions remain regarding the applicability and limitations of applying various PD models to early and later life. In the present paper, we provide an overview of such dimensional models and review current proposals for conceptualizing PDs inDSM-V. Next, we extensively review existing evidence on the development, measurement, and manifestation of personality pathology in early and later life focusing on those issues deemed most relevant for informingDSM-V. Finally, we present overall conclusions regarding the need to incorporate developmental issues in conceptualizing PDs inDSM-Vand highlight the advantages of a dimensional model in unifying PD perspectives across the life span.

scholarly journals Higher Neutrophil-lymphocyte Ratio in TB/HIV Co-infection Compared to Pulmonary Tuberculosis

2021 ◽  
Vol 13 (4) ◽  
pp. 375-82
Author(s):  
Nuni Sulastri ◽  
Bachti Alisjahbana ◽  
Resvi Livia ◽  
Edhyana Sahiratmadja
Keyword(s):  
Pulmonary Tuberculosis ◽  
Complete Blood Count ◽  
Inflammatory Marker ◽  
Cross Sectional Study ◽  
High Ratio ◽  
Sectional Study ◽  
Cross Sectional ◽  
Pulmonary Tb ◽  
Neutrophil Lymphocyte Ratio ◽  
Potential Marker

BACKGROUND: Neutrophils and lymphocytes play a significant role in inflammation and a high ratio of neutrophils over lymphocytes (NLR) has been used as an inflammatory marker to predict the severity of various diseases. Here we compared the NLR among pulmonary tuberculosis and TB/HIV co-infection.METHODS: A retrospective cross-sectional study was conducted, included patients with pulmonary TB without cavitation TB (n=50), with cavitation TB (n=50) and HIV co-infection (n=27). Complete blood count was examined, including neutrophils and lymphocyte. NLR was calculated and compared between groups. RESULTS: Neutrophils were significantly higher (p=0.004) in TB with cavitation compared to those with no cavitation (8.27±1.45 x103/μL vs. 6.61±1.4 x103/μL, respectively); whereas the lymphocytes were similar in both groups, resulting in a significantly higher NLR (p=0.009) in pulmonary TB with cavitation compared to pulmonary TB with no cavitation (5.98±1.85 vs. 4.42±1.86, respectively). On the contrary, both neutrophils as well as lymphocyte were significantly lower in TB/HIV compared to pulmonary TB, which for neutrophil were 5.14±2.19 x103/μL vs. 7.4±1.45 x103/μL, respectively (p=0.003) and for lymphocyte (1.02 ±0.57 x103/μL vs. 1.57±0.64 x103/μL, respectively (p=0.001), resulting in a significantly higher (p=0.041) NLR value in TB/HIV (6.05±2.67) compared to pulmonary TB (5.16±1.88).CONCLUSION: High NLR in pulmonary TB with cavitation as well as in TB with HIV co-infection may be of great interest for biomarker in TB severity. Further study confirming NLR as potential marker is imperative.KEYWORDS: lymphocyte, neutrophil, NLR, tuberculosis, TB/HIV

Sign in / Sign up

Export Citation Format

Share Document