scholarly journals Motor control of Drosophila feeding behavior

eLife ◽  
2017 ◽  
Vol 6 ◽  
Author(s):  
Olivia Schwarz ◽  
Ali Asgar Bohra ◽  
Xinyu Liu ◽  
Heinrich Reichert ◽  
Krishnaswamy VijayRaghavan ◽  
...  

The precise coordination of body parts is essential for survival and behavior of higher organisms. While progress has been made towards the identification of central mechanisms coordinating limb movement, only limited knowledge exists regarding the generation and execution of sequential motor action patterns at the level of individual motoneurons. Here we use Drosophila proboscis extension as a model system for a reaching-like behavior. We first provide a neuroanatomical description of the motoneurons and muscles contributing to proboscis motion. Using genetic targeting in combination with artificial activation and silencing assays we identify the individual motoneurons controlling the five major sequential steps of proboscis extension and retraction. Activity-manipulations during naturally evoked proboscis extension show that orchestration of serial motoneuron activation does not rely on feed-forward mechanisms. Our data support a model in which central command circuits recruit individual motoneurons to generate task-specific proboscis extension sequences.

Author(s):  
Rajendra Pai N. ◽  
U. Govindaraju

Ayurveda in its principle has given importance to individualistic approach rather than generalize. Application of this examination can be clearly seem like even though two patients suffering from same disease, the treatment modality may change depending upon the results of Dashvidha Pariksha. Prakruti and Pramana both used in Dashvidha Pariksha. Both determine the health of the individual and Bala (strength) of Rogi (Patient). Ayurveda followed Swa-angula Pramana as the unit of measurement for measuring the different parts of the body which is prime step assessing patient before treatment. Sushruta and Charaka had stated different Angula Pramana of each Pratyanga (body parts). Specificity is the characteristic property of Swa-angula Pramana. This can be applicable in present era for example artificial limbs. A scientific research includes collection, compilation, analysis and lastly scrutiny of entire findings to arrive at a conclusion. Study of Pramana and its relation with Prakruti was conducted in 1000 volunteers using Prakruti Parkishan proforma with an objective of evaluation of Anguli Pramana in various Prakriti. It was observed co-relating Pramana in each Prakruti and Granthokta Pramana that there is no vast difference in measurement of head, upper limb and lower limb. The observational study shows closer relation of features with classical texts.


Author(s):  
Abbie J. Shipp

Temporal focus is the individual tendency to characteristically think more or less about the past, present, and future. Although originally rooted in early work from psychology, research on temporal focus has been steadily growing in a number of research areas, particularly since Zimbardo and Boyd’s (1999) influential article on the topic. This chapter will review temporal focus research from the past to the present, including how temporal focus has been conceptualized and measured, and which correlates and outcomes have been tested in terms of well-being and behavior. Based on this review, an agenda for research is created to direct temporal focus research in the future.


2021 ◽  
Author(s):  
Qiushi Wang ◽  
Yuehua Xu ◽  
Tengda Zhao ◽  
Zhilei Xu ◽  
Yong He ◽  
...  

Abstract The functional connectome is highly distinctive in adults and adolescents, underlying individual differences in cognition and behavior. However, it remains unknown whether the individual uniqueness of the functional connectome is present in neonates, who are far from mature. Here, we utilized the multiband resting-state functional magnetic resonance imaging data of 40 healthy neonates from the Developing Human Connectome Project and a split-half analysis approach to characterize the uniqueness of the functional connectome in the neonatal brain. Through functional connectome-based individual identification analysis, we found that all the neonates were correctly identified, with the most discriminative regions predominantly confined to the higher-order cortices (e.g., prefrontal and parietal regions). The connectivities with the highest contributions to individual uniqueness were primarily located between different functional systems, and the short- (0–30 mm) and middle-range (30–60 mm) connectivities were more distinctive than the long-range (>60 mm) connectivities. Interestingly, we found that functional data with a scanning length longer than 3.5 min were able to capture the individual uniqueness in the functional connectome. Our results highlight that individual uniqueness is present in the functional connectome of neonates and provide insights into the brain mechanisms underlying individual differences in cognition and behavior later in life.


Author(s):  
Leah S. Hartman ◽  
Stephanie A. Whetsel Borzendowski ◽  
Alan O. Campbell

As the use of surveillance video at commercial properties becomes more prevalent, it is more likely an incident involving a personal injury will be captured on film. This provides a unique opportunity for Human Factors practitioners involved in forensic investigations to analyze the behavior of the individual prior to, during, and after the event in question. It also provides an opportunity to gather unique and objective data. The present work describes a case study of a slip and fall where surveillance video and onsite measurements were combined and analyzed to quantify a plaintiff’s gait pattern. Using this type of analysis, we were able to determine that the plaintiff was likely aware that the floor was slippery and adjusted her gait and behavior prior to the slip and fall incident.


2021 ◽  
Vol 11 (2) ◽  
pp. 167
Author(s):  
Rubén Pérez-Elvira ◽  
Javier Oltra-Cucarella ◽  
José Antonio Carrobles ◽  
Minodora Teodoru ◽  
Ciprian Bacila ◽  
...  

Learning disabilities (LDs) have an estimated prevalence between 5% and 9% in the pediatric population and are associated with difficulties in reading, arithmetic, and writing. Previous electroencephalography (EEG) research has reported a lag in alpha-band development in specific LD phenotypes, which seems to offer a possible explanation for differences in EEG maturation. In this study, 40 adolescents aged 10–15 years with LDs underwent 10 sessions of Live Z-Score Training Neurofeedback (LZT-NF) Training to improve their cognition and behavior. Based on the individual alpha peak frequency (i-APF) values from the spectrogram, a group with normal i-APF (ni-APF) and a group with low i-APF (li-APF) were compared in a pre-and-post-LZT-NF intervention. There were no statistical differences in age, gender, or the distribution of LDs between the groups. The li-APF group showed a higher theta absolute power in P4 (p = 0.016) at baseline and higher Hi-Beta absolute power in F3 (p = 0.007) post-treatment compared with the ni-APF group. In both groups, extreme waves (absolute Z-score of ≥1.5) were more likely to move toward the normative values, with better results in the ni-APF group. Conversely, the waves within the normal range at baseline were more likely to move out of the range after treatment in the li-APF group. Our results provide evidence of a viable biomarker for identifying optimal responders for the LZT-NF technique based on the i-APF metric reflecting the patient’s neurophysiological individuality.


Nutrients ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 199
Author(s):  
Kathrin Cohen Kadosh ◽  
Leilani Muhardi ◽  
Panam Parikh ◽  
Melissa Basso ◽  
Hamid Jan Jan Mohamed ◽  
...  

Proper nutrition is crucial for normal brain and neurocognitive development. Failure to optimize neurodevelopment early in life can have profound long-term implications for both mental health and quality of life. Although the first 1000 days of life represent the most critical period of neurodevelopment, the central and peripheral nervous systems continue to develop and change throughout life. All this time, development and functioning depend on many factors, including adequate nutrition. In this review, we outline the role of nutrients in cognitive, emotional, and neural development in infants and young children with special attention to the emerging roles of polar lipids and high quality (available) protein. Furthermore, we discuss the dynamic nature of the gut-brain axis and the importance of microbial diversity in relation to a variety of outcomes, including brain maturation/function and behavior are discussed. Finally, the promising therapeutic potential of psychobiotics to modify gut microbial ecology in order to improve mental well-being is presented. Here, we show that the individual contribution of nutrients, their interaction with other micro- and macronutrients and the way in which they are organized in the food matrix are of crucial importance for normal neurocognitive development.


2021 ◽  
Vol 6 (2) ◽  
pp. 84
Author(s):  
Dyah Ayu Widiasih ◽  
Johanna Frida Lindahl ◽  
Wayan T. Artama ◽  
Adi Heru Sutomo ◽  
Pande Made Kutanegara ◽  
...  

Leptospirosis is a zoonotic disease occurring worldwide with reproductive symptoms and production losses in livestock, while humans can suffer fatal renal failure. In Yogyakarta Special Province, Indonesia, there have been several outbreaks with high case fatality, demonstrating the public health importance, but there is limited understanding of the epidemiology. This study used an EcoHealth approach to ensure transdisciplinarity and community participation. Seroprevalence of Leptospira in animals was studied between October 2011 and May 2013 in 15 villages. Serum samples from 1404 cattle and 60 small ruminants were screened by a Microscopic Agglutination Test (MAT), first in pools, and then the individual positive samples were identified. Focus group discussions including farmers, village officials, and official stakeholders were used to explore knowledge and behavior of zoonotic diseases, particularly leptospirosis. Two small ruminants were seropositive for Leptospira icterohemorrhagiae. From the cattle, 3.7% were seropositive, and the most common serovars were Leptospira hardjo, followed by L. icterohemorrhagiae. Out of all farms, 5.6% had at least one positive cattle. Risk factor analyses showed that the risk of the farm being seropositive increased if the farmer used water from an open source, or if farming was not the main occupation. This study showed the presence of Leptospira spp. in ruminants in Yogyakarta and identified use of open water as a risk factor for the livestock. We also observed that the knowledge related to leptospirosis was low, and risky farm management practices were commonly employed.


2012 ◽  
Vol 546-547 ◽  
pp. 248-253
Author(s):  
Jing Jing Xiong ◽  
Zhen Feng ◽  
Jiao Yu Liu

In this paper, based on the principle of the speed and current double closed loop DC regulating system and the requirement of the static and dynamic performance, we calculate time constant of the regulator, select the structure of the regulator to calculate related parameter and then correct its parameters, and model system and simulation by using Simulink, analysis waveform and debug to find out the optimal parameters of the system regulator to guide the actual system design.


Author(s):  
Jovana Jovanova ◽  
Maja Anachkova ◽  
Viktor Gavriloski ◽  
Dimitar Petrevski ◽  
Franka Grazhdani ◽  
...  

Arthropod animals like scorpions with modular body parts can be an inspiration for a robot’s structure. The design presented here relays on inter-connected origami towers, but could also be easily disassembled. Each origami tower is fully autonomous and at the same time is part of the robot as a whole. The towers are positioned between two platforms that enable modularity. The scorpion’s tale shape is achieved by the varying platform diameter resulting in cone-like form. Each tower is actuated independently to enable multiple degrees of freedom. Maneuvering with separated units, assists in easier reparation as well as replacement. Detaching the towers into separate parts makes this structure develop more precise movements, since every unit will move autonomously. Therefore, having a higher number of separated movements combined leads to a smooth bionic movement. So, the overall hierarchy will be modular contributing to a greater curvature bending of the whole structure. Actuating and maneuvering the robot in the main concept is done by separated electro motors, built in the platform. The basic structure will be built from thick paper with plastic coatings. The thick paper itself is lightweight, but at the same time flexible. To protect the paper towers, double plastic foil is placed as an outer coating which acts as an origami cover. This transparent layer is elastic hence it can follow and support the individual units’ movements. This work is focused on understanding origami towers kinematics and different combinations of inter-connected towers to achieve multiple degrees of freedom. A conceptual model is developed, supported by CAD and mathematical models. At the end a prototype is presented.


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