scholarly journals A CRITICAL REVIEW ON PUSHKARMOOLADI YOGA IN SHWASA ROGA

2022 ◽  
Vol 12 (6) ◽  
pp. 64-68
Author(s):  
Khobragade Swapnil ◽  
Upadhyay Prem Shanker
Keyword(s):  
Antimicrobial Activity ◽  
Phenolic Compound ◽  
Bronchial Asthma ◽  
Critical Review ◽  
Antioxidant Properties ◽  
Smooth Muscles ◽  
Inflammatory Disorder ◽  
Research Papers ◽  
Chronic Inflammatory Disorder ◽  
Asthma Symptoms

Shwasa is a disease of Pranavaha strotas. It is clinically correlated with bronchial asthma. Symptoms of Shwasa are nearly similar to Bronchial Asthma, a chronic inflammatory disorder of the airways. Pushkarmoladi yoga is described in Yoga Ratnakara and Bhaishjya Ratnavali. This yoga contains Pushkarmoola, Pippali, Dhanvayasa, Karkatshringi and Ativisha. This study was conducted to know the efficacy of Pushkarmoola diyoga in Shwasa (Bronchial Asthma). The literary review was performed by a collection of material related to the clinical efficacy of Pushkarmooladiyoga with the help of several essential Ayurvedic and Modern textbooks, Research papers and journals. Pushkarmooladi yoga shows bronchodilator property by relaxation of bronchial smooth muscles and antimicrobial activity against various gram +ve and gram-ve bacteria, which are responsible for Shwasa and have antioxidant properties due to the presence of the particular phenolic compound in its ingredients.

A Critical Review on Tamaka Shwasa (Bronchial Asthma) - An Ayurvedic View

2017 ◽  
Vol 2 (3) ◽  
Author(s):  
Sandip R. Baheti ◽  
Deepa Sharma ◽  
Saroj Devi ◽  
Amit Rai
Keyword(s):  
Bronchial Asthma ◽  
Inflammatory Disease ◽  
Critical Review ◽  
Modern Science ◽  
Modern Medicine ◽  
Chronic Inflammatory Disease ◽  
The Body ◽  
Natural Immunity ◽  
Shortness Of Breath ◽  
Asthma Symptoms

Difficulty in breathing or shortness of breath may be simply termed as Shwasa (Asthma), As per Ayurveda, Shwasa is mainly caused by the Vata and Kapha Doshas. Shwasa is broadly classified into five types in Maha Shwasa (Dyspnoea major), Urdhawa Shwasa (Expiratory Dyspnoea), Chinna Shwasa (Chyne-stroke respiration), Kshudra Shwasa (Dyspnoea minor), Tamaka Shwasa (Bronchial Asthma). In modern science Tamaka Shwasa can be correlated with Asthma, Asthma which is a chronic inflammatory disease of airway. In modern medicine there is no cure for Asthma, symptoms can typically be improved. In Ayurveda, Asthma can be effectively and safely manage the condition without inducing any drug dependency where Pachakarma procedures and use of internal medication detoxifies the body, provides nutrition and increases the elasticity of lung tissue it also develops natural immunity of the body thus decreasing episodic recurrence of the disease.

scholarly journals The Impact of Food Histamine Intake on Asthma Activity: A Pilot Study

Nutrients ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 3402
Author(s):  
Emilia Vassilopoulou ◽  
George N. Konstantinou ◽  
Anastasia Dimitriou ◽  
Yannis Manios ◽  
Lemonica Koumbi ◽  
...  
Keyword(s):  
Food Choice ◽  
Dietary Intervention ◽  
Peak Flow ◽  
Inflammatory Disorder ◽  
Intervention Period ◽  
Chronic Inflammatory Disorder ◽  
Asthma Symptoms ◽  
Intervention Adherence ◽  
The Impact ◽  
Intermittent Asthma

Asthma is a complex chronic inflammatory disorder. Diet’s impact on asthma symptoms is controversial. The objective of this pilot crossover, randomized, two-period study was to examine the effect of dietary histamine intake on asthma symptoms in twenty-one children with mild intermittent asthma. Children were randomly assigned to either a high- or low-histamine diet, based on the Mediterranean pattern, for 4 weeks. After a 2-week washout period, patients crossed to the alternative diet for 4 additional weeks. Asthma symptoms were assessed at baseline and after the completion of each diet period by a clinician. Daily symptoms and peak flow were recorded throughout the intervention. Adherence to the dietary intervention was assessed via analysis of four random 24-h recalls, for each intervention period. Eighteen children completed the study. Significantly higher mean air flow obstruction was recorded and a trend for prolonged and more severe symptoms was observed during the high-histamine period. Diet may have an active and direct impact on asthma symptoms. Food choice is affected and/or may affect symptoms in children with mild asthma. Diet intervention is promising yet challenging, for asthma control.

scholarly journals Study of efficacy and adverse effect of fluticasone and formoterol combination in bronchial asthma

2020 ◽  
Vol 9 (10) ◽  
pp. 1509
Author(s):  
Sharad Chaddha ◽  
Tajinder Kaur
Keyword(s):  
Adverse Effect ◽  
Bronchial Asthma ◽  
Forced Expiratory Volume ◽  
Dose Inhaler ◽  
Inflammatory Disorder ◽  
Pulmonary Medicine ◽  
Chronic Inflammatory Disorder ◽  
Medical College ◽  
Metered Dose ◽  
The Mean

Background: Bronchial asthma is a chronic inflammatory disorder of the airways associated with airway hyperresponsiveness that leads to recurrent episodes of wheezing, breathlessness, chest tightness and coughing particularly at night or in the early morning.Methods: This study has recruited 25 newly (male/female) cases of Bronchial Asthma diagnosed on the basis of spirometry in the Department of Pulmonary Medicine, Era’s Lucknow Medical College & Hospital (ELMC&H). Patients were received Fluticasone/Formoterol (200/10 μg OD). The drugs were administered through metered-dose inhaler (MDI).Results: The mean forced expiratory volume recorded before treatment 54.92±4.47 in a group who were treated with formoterol/fluticasone combination changed to 75.48±5.03 after the treatment. No significant adverse effect of this regimens was observed.Conclusions: The results of this study revealed this regimen showed a significant improvement in lung functions without any significant adverse event.

scholarly journals Vitamin D levels in children with bronchial asthma

2020 ◽  
Vol 7 (11) ◽  
pp. 2163
Author(s):  
Kaisar R. Wani ◽  
Reyaz A. Malik Malik ◽  
Asif Ahmed
Keyword(s):  
Vitamin D ◽  
Bronchial Asthma ◽  
Serum Vitamin ◽  
Inflammatory Disorder ◽  
Healthy Children ◽  
Chronic Inflammatory Disorder ◽  
Asthmatic Children ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
The Mean

Background: Bronchial asthma is a common chronic inflammatory disorder of the airways in childhood. Vitamin D, initially described as a vitamin that regulated calcium homeostasis, has also been shown to exert important antimicrobial effects and is also a potent immune system regulator having a potential role in various allergic diseases. The main objective of this study was to look the levels of vitamin D in children with bronchial asthma and to study the co relationship between vitamin D levels and severity of asthma.Methods: This study included 80 (40 asthmatic children and 40 healthy controls) children aged between 4 and 15 year. Serum vitamin D levels where determined and compared between the two groups. The association between vitamin D levels and severity of asthma was studied in the asthmatic children.Results: Among 40 asthmatic children the mean serum vitamin D level was 16.6±11.56 ng/ml, while as the mean vitamin D levels in healthy control subjects was 24.225±2.764 ng/ml and the difference between the two groups was statistically significant (p=0.001). Vitamin D deficiency was highly prevalent in asthmatic patients and there was a direct and a significant relationship between serum vitamin D levels and severity of asthma.Conclusion: In this study, vitamin D levels were considerably lower in children with asthma than in healthy children. Also, in this study vitamin D deficient asthma patients have more severe asthma than the patients who have sufficient vitamin D levels.

scholarly journals A COMPARATIVE CLINICAL STUDY ON THE EFFECTIVENESS OF BHARANGYADI CHOORNA AND VYAGHRI CHOORNA IN TAMAKA SWASA (BRONCHIAL ASTHMA)

2020 ◽  
pp. 70-78
Author(s):  
Devanand E ◽  
K Ravindra Bhat
Keyword(s):  
Clinical Study ◽  
Bronchial Asthma ◽  
Modern Science ◽  
Signs And Symptoms ◽  
Wilcoxon Test ◽  
Control Group ◽  
Inflammatory Disorder ◽  
Chronic Inflammatory Disorder ◽  
Comparative Clinical Study ◽  
Group B

Ayurveda classics mentioned various types of Swasa and Tamaka Swasa is one among them. Tamakaswasa is manifested by aggravated Pranavayu by the obstruction of Kapha. In this case treatment should be to clear out Pranavaha srotas, pacify Vata and remove the blockage due to Kapha. In modern science Tamaka Swasa is correlated with Bronchial Asthma. It’s a chronic inflammatory disorder of the airways in which the chronic inflammation causes an associated increase in airway hyper responsiveness that leads to recurrent episodes of asthmatic exacerbation. Modern science has no permanent cure of Tamaka Swasa, that’s why it is necessity to search herbal and herbo-mineral preparations for the treatment of disease. Present Study was conducted to reduce the symptoms of Tamakaswasa. Bharangyadi Choorna and Vyaghri Choorna have the properties of Kapha Vata hara, Agni Deepana, Pachana, Anulomana, Srotoshodhana, anti-asthamatic and anti-inflammatory property. Materials and Method: Patients who have symptoms of Tamakaswasa fulfill the inclusion criteria were given with Bharangyadi Choorna 4gm thrice a day along with Ardraka Swarasa as Anupana in the trail group i.e., group A and Vyaghri Choorna 4gm thrice a day along with honey as Anupana in the control group i.e. group B. It is a comparative clinical study with 30 patients in each group for 30 days. Analyzing the signs and symptoms, PEFR after each 10 days, Wilcoxon test was done for comparing the effectiveness of treatment between two groups. Comparative analysis of the overall effect of the treatments in both the groups was done by statistically done by Mann-Whitney test. Results: There was statistically significant change in all the signs and symptoms and PEFR after treatment and follow up. All the signs and symptoms have P ≤ 0.05. Conclusion: Bharangyadi Choorna has shown highly significant reduction in the symptoms like Swasakrichratha, Peenasa, Kasa, Ghurghuraka, Krichrabhashana, Shushkasya and PEFR. On comparison between the two groups, Bharangyadi choorna showed a better result in improvement of symptoms- Swasakrichratha, Peenasa, Kasa, Ghurghuraka, Krichrabhashana, Shushkasya and objective parameter- PEFR. Hence H2 hold good.

scholarly journals A clinical study of Shunthyadi churna in the Management of Tamaka shwasa W.S.R. to Bronchial Asthma

2018 ◽  
Vol 4 (2) ◽  
pp. 48-52
Author(s):  
Rajnik Jadav ◽  
◽  
Alankruta Dave ◽  
Jitendra Varsakiya ◽  
◽  
...  
Keyword(s):  
Bronchial Asthma ◽  
Airway Hyperresponsiveness ◽  
Modern Science ◽  
Inflammatory Disorder ◽  
Age Group ◽  
Inclusion Criteria ◽  
Chronic Inflammatory Disorder ◽  
Permanent Cure ◽  
Effective Remedy

In classics Tamaka Shwasa is Pitta Sthana Samudbhava Vhadhi, mainly affected Doshas are Vata and Pitta. In modern science Tamaka Swasa is correlate with bronchil ashtha, Symptoms of Tamaka Swasa is nearly similar to. Bronchial asthma a chronic inflammatory disorder of the airways in which the chronic inflammation causes an associated increase in airway hyperresponsiveness that leads to recurrent episodes of asthmatic exacerbation. Modern science has no permanent cure of Tamaka Swasa, thats why it is necessity to search herbal and herbo-minaral preparations for the treatment of disease. It is safe and effective in asthma. Shunthyadi Churna described in Yogratnakara for the treatment of Shwasa. Aim: Role of Shunthyadi Churna in treatment of Tamaka Shwasa. Materials and Methods: Total 23 patients of Tamaka Shwasa age group of 18 to 60 years fulfilling the inclusion criteria were selected for trial. Disscussion: Properties having Shuthyadi Churna is Tikta Katu Rasa, Laghu and Tikna Guna (light and penetrating properties), Ushna Virya (hot potency) and Vatakaphagna (decrease Vata and Kapha Dosha). Shuthyadi Churna is effective in break down the Samprapti of Tamaka Swasa and effective remedy for the patient of bronchial asthma.

scholarly journals The role of psychic factors in the pathogenesis of bronchial asthma

2011 ◽  
Vol 139 (3-4) ◽  
pp. 209-215 ◽  
Author(s):  
Danijela Vucevic ◽  
Tatjana Radosavljevic ◽  
Dusan Mladenovic ◽  
Vera Todorovic
Keyword(s):  
Bronchial Asthma ◽  
Emotional Stress ◽  
Early Morning ◽  
Inflammatory Disorder ◽  
Chronic Inflammatory Disorder ◽  
Asthmatic Patients ◽  
Increased Sensitivity ◽  
Personality Features ◽  
Stress Pathway

Bronchial asthma is a chronic inflammatory disorder of the airways in which many cells play a role, in particular mast cells, eosinophils, neutrophils, T-lymphocytes and epithelial cells. In susceptible individuals this inflammation causes recurrent episodes of wheezing, breathlessness, chest tightness and cough, particularly at night and/or in the early morning. These symptoms are usually associated with variable and extensive limitations of airflow in the bronchi reversible spontaneously or by treatment. It has been shown that restrain of the effectors of stress response participate in the pathogenesis of bronchial asthma. Anger that is not expressed and frustrations may activate the limbic stress pathway. Thus, the released neurotransmitters followed by excitation thus causing psychogenic (mental or emotional) stress. It is also known that emotional stress may be responsible for the exacerbation of asthma. Namely, pronounced emotions cause hyperventilation and hypocapnia inducing bronchospasm. Certain psychological personality features are related to adaptive or inadequate body response to numerous life events. Thus, until the beginning of the last century, bronchial asthma was referred to as asthma nervosa, because clinicians clearly observed the psychological profile of patients with predominant fear of asphyxia and recurrent attacks of paroxysmal dyspnoea. Besides, increased sensitivity, repression of aggressive feelings and expressive empathy have been identified as the most frequent psychological characteristics of asthmatic patients. However, scientists are still far from a full understanding of bronchial asthma pathogenesis. The contribution of psychic factors has become meaningful in the understanding of the development of bronchial asthma. Having in mind that in the majority of patients asthma is a lifelong condition, there is a hope that further investigations of bronchial asthma psychogenesis will improve prevention and treatment of this disease.

scholarly journals Redox Imbalance in T Cell-Mediated Skin Diseases

2010 ◽  
Vol 2010 ◽  
pp. 1-9 ◽  
Author(s):  
Saveria Pastore ◽  
Liudmila Korkina
Keyword(s):  
Oxidative Stress ◽  
Atopic Dermatitis ◽  
Contact Dermatitis ◽  
Skin Diseases ◽  
Redox Balance ◽  
Inflammatory Disorder ◽  
Chronic Inflammatory Disorder ◽  
Physical Chemical ◽  
Chemical Oxidants ◽  
Beneficial Outcome

The skin is permanently exposed to physical, chemical, and biological aggression by the environment. In addition, acute and chronic inflammatory events taking place in the skin are accompanied by abnormal release of pro-oxidative mediators. In this paper, we will briefly overview the homeostatic systems active in the skin to maintain the redox balance and also to counteract abnormal oxidative stress. We will concentrate on the evidence that a local and/or systemic redox dysregulation accompanies the chronic inflammatory disorder events associated to psoriasis, contact dermatitis, and atopic dermatitis. We will also discuss the fact that several well-established treatments for the therapy of chronic inflammatory skin disorders are based on the application of strong physical or chemical oxidants onto the skin, indicating that, in selected conditions, a further increase of the oxidative imbalance may lead to a beneficial outcome.

scholarly journals Rituximab Treatment in a Patient with Kimura Disease and Membranous Nephropathy: Case Report

2021 ◽  
pp. 116-123
Author(s):  
Roald Vissing-Uhre ◽  
Alastair Hansen ◽  
Susanne Frevert ◽  
Ditte Hansen
Keyword(s):  
Case Report ◽  
Membranous Nephropathy ◽  
Neck Region ◽  
Renal Diseases ◽  
Kimura’S Disease ◽  
Inflammatory Disorder ◽  
Kimura Disease ◽  
Chronic Inflammatory Disorder ◽  
Eosinophil Granulocytes ◽  
Anti Cd20

Kimura disease (KD) is a chronic, inflammatory disorder with slowly developing subcutaneous tumor-like swellings, often occurring in the head and neck region. KD is diagnosed based on histology, elevated levels of immunoglobulin type E, and increased peripheral eosinophil granulocytes. KD may coexist with glomerular renal diseases, and this case report is based on a patient with KD-associated membranous nephropathy. Patients with membranous nephropathy without KD have demonstrated responsiveness to treatment with monoclonal anti-CD20 antibodies. This case report is the first to investigate the effect of rituximab treatment in a patient with KD-associated membranous nephropathy. A 30-year-old Italian man living in Denmark was diagnosed with Kimura’s disease based on subcutaneous nodules with eosinophil angiolymphoid hyperplasia. The patient was admitted to the hospital due to nephrotic syndrome. Serology showed eosinophil granulocytosis and negative PLA2-receptor antibody. Renal biopsy showed membranous nephropathy, and the patient was treated with systemic methylprednisolone followed by cyclosporin and then cyclophosphamide with only partial remission. Ultimately, treatment with intravenous rituximab was initiated, which resulted in overall remission and no nephrotic relapses at 30 months of follow-up. Thus, intravenous rituximab effectively decreased proteinuria and prevented nephrotic relapses in a patient with treatment-refractory membranous nephropathy due to KD.

scholarly journals Serum-derived extracellular vesicles inhibit osteoclastogenesis in active-phase patients with SAPHO syndrome

2021 ◽  
Vol 13 ◽  
pp. 1759720X2110069
Author(s):  
Yanpan Gao ◽  
Yanyu Chen ◽  
Lun Wang ◽  
Chen Li ◽  
Wei Ge
Keyword(s):  
Bone Metabolism ◽  
Extracellular Vesicles ◽  
Inflammatory Marker ◽  
Active Phase ◽  
Sapho Syndrome ◽  
Inflammatory Disorder ◽  
Chronic Inflammatory Disorder ◽  
Reactive Protein ◽  
Amyloid A

Objective: Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare chronic inflammatory disorder and the underlying pathogenesis is unclear. In this study, 88 SAPHO patients and 118 healthy controls were recruited to investigate the role of serum-derived extracellular vesicles (SEVs) in SAPHO syndrome. Methods: Quantitative proteomics was applied for SEVs proteome identification, and ELISA and Western blotting was performed to verify the results of mass spectrum data. In vitro osteoclastogenesis and osteogenesis assay was used to confirm the effects of SEVs on bone metabolism. Results: Tandem mass tagging-based quantitative proteomic analysis of SAPHO SEVs revealed differential expressed proteins involved in bone metabolism. Of these, serum amyloid A-1 (SAA1) and C-reactive protein (CRP) were upregulated. Higher SAA1 levels in SAPHO patients were confirmed by ELISA. In addition, SAA1 levels were positively correlated with CRP, an inflammatory marker related to the condition of patients. In vitro celluler studies confirmed that SAPHO SEVs inhibited osteoclastogenesis in patients mainly in the active phase of the disease. Further analysis demonstrated that Nucleolin was upregulated in osteoclasts of active-phase patients under SAPHO SEVs stimulation. Conclusion: In this study, we identified SAA1 as an additional inflammation marker that can potentially assist the diagnosis of SAPHO syndrome, and speculated that Nucleolin is a key regulator of osteoclastogenesis in active-phase patients.

Sign in / Sign up

Export Citation Format

Share Document