scholarly journals HIV and HBV Coinfections in the Highly HIV-infected Population of Rivers State, Nigeria

Author(s):  
Tochi I. Cookey ◽  
Iheanyi O. Okonko ◽  
Nnenna Frank-Peterside

Background: In Nigeria, hepatitis co-infection with HIV is linked with an increase in morbidity and mortality. Objective: The goal of this study was to investigate the rate of HIV/HBV coinfection among the highly HIV-infected people in Rivers State, Nigeria. Study Design:  Cross-sectional study. Place and Duration of Study: University of Port Harcourt Teaching Hospital (UPTH), in Rivers State, Nigeria, from February 2017 to September 2019. Methods: A total of 226 HIV-positive people, 105 men and 121 women, were recruited for this study. ELISA was used to screen these participants for the presence of HIV and HBsAg, and this was done following the guidelines stipulated by the manufacturer. The demographic characteristics of the participants were obtained using a questionnaire designed for the study. Results: Seven people tested positive for HIV/HBV, resulting in a 3.1 % overall prevalence. No significant association was found to exist between HIV/HBV coinfection and the characteristics of the study population. Conclusion: A low seroprevalence was observed for HIV/HBV infection, in spite of Nigeria being endemic for HBV. Despite this low rate of HIV/HBV coinfection, routine screening for HBV markers should be carried out to reduce morbidity and mortality in this group.

2017 ◽  
Vol 11 (02) ◽  
pp. 238-241 ◽  
Author(s):  
Shrikanth Muralidharan ◽  
Arunkumar Acharya ◽  
Shanthi Margabandhu

ABSTRACTObjective: The aim of the study was to assess the dentition status and the treatment needs of the HIV-positive patients on ART for more than a year in Raichur, Karnataka. Materials and Methods: Convenience sampling was followed. The sample size was 170. The dentition status and treatment needs of the patients were recorded as per the WHO guidelines. Results: The overall prevalence of dental caries was 79.4%. Males had higher percentage of dental caries than the females, and this was found to be statistically significant. The prevalence of dental caries was higher among the participants who used finger to clean their teeth compared to the toothbrush, neem stick, and charcoal users, and this was found to be statistically significant. Conclusion: Higher prevalence of dental caries was observed among the study population. Most of them required some type of treatment. Patients with a low CD4 count required higher treatments than the others.


Author(s):  
Barinua K. Gbaranor ◽  
Clinton D. Orupabo ◽  
Nazor P. Barinua Gbaranor ◽  
Peace E. Okpara ◽  
Progress D. Victor

Background: Fibroid is a gynaecological problem that affects women of reproductive age across the globe especially among the black race. This study was done to evaluate the incidence of fibroid and its effects on fertility in Eleme Local Government Area.Methods: It is a cross-sectional study with 60 participants aged 18-28 years, 29-39 years, 40-49 years, 50-59 years and >60 years.Results: The study revealed that 90% of the respondents have fibroid and 10% do not have fibroid. The effects range from painful menstruation, heavy menses, irregular menstruation and infertility at the values of 63.3%, 48.3%, 51.7% and 86.8% respectively.Conclusions: Though the effects of fibroids are universal, our study population seems to show some effects more common to them.


2017 ◽  
Vol 56 (6) ◽  
pp. 325
Author(s):  
Surya Jayanti Kadek ◽  
Dewi Kumara Wati Ketut ◽  
Karyana Putu Gede

Background About 60% of individuals with atopic dermatitis (AD) develop their first manifestation during infancy. Cow’s milk (CM) exposure is considered to be a risk factor for AD.Objective To evaluate for an association between cow’s milk exposure and atopic dermatitis in infants > 6 months of age.  Methods This cross-sectional study consisted of subjects from a previous study and new subjects recruited in order to meet the minimum required number of subjects. Our study population comprised 120 infants, born between 1 February and 30 November, 2012 in Sanglah Hospital, Denpasar. Subjects were divided into CM and non-CM groups and analyzed for their risk of AD. Subjects were included to CM group if they were fed with cow’s milk/formula  and included to non-CM group if they were breastfeed exclusively in the first six months of life. Other possible risk factors were assessed by multivariate analysis. Results One hundred twenty subjects were enrolled and analyzed (59 in the CM and 61 in the non-CM groups). The prevalence of AD was 30%. Multiple logistic regression analysis revealed a significant association between CM exposure and AD, with odds ratio (OR) 2.37 (95%CI 1.036 to 5.420; P=0.04). In addition, maternal diet including eggs and/or cow’s milk during the breastfeeding period was significantly associated with AD in infants (OR 3.18; 95%CI 1.073 to 9.427; P=0.04).Conclusion Cow’s milk exposure is significantly associated with atopic dermatitis in infants  > six months of age. 


2013 ◽  
Vol 22 (1) ◽  
pp. 141-148 ◽  
Author(s):  
Fabiana de Souza Orlandi ◽  
Neide de Souza Praça

This descriptive cross-sectional study had the objective to evaluate the level of hope in women aged 50 or older suffering from HIV/AIDS, utilizing the Herth Hope Scale. The study involved 200 HIV- positive women, within the age bracket of interest, enrolled in three STI/AIDS specialized healthcare services in the city of São Paulo. The rules of the 196/96 Resolution were met and the study was approved by the Research and Ethics Committee. Data were collected in 2010 using two instruments: subjects' characterization and the Herth Hope Scale. Results demonstrated an average score of 36.75 (±4.52) on the Herth Hope Scale, with an interval of 12 to 48. This score is below the score obtained with the same scale for various pathologies, indicating a reduced perception of hope by the sample. Nurses should provide interventions to improve hope for these people, establishing realistic goals and strengthening social support.


Contraception ◽  
2018 ◽  
Vol 98 (6) ◽  
pp. 492-497 ◽  
Author(s):  
K.M. Tote ◽  
V.T. Raziano ◽  
K.M. Wall ◽  
S. Cordes ◽  
I. Ofotokun ◽  
...  

BMJ Open ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. e043941
Author(s):  
Tafadzwa Dhokotera ◽  
Julia Bohlius ◽  
Matthias Egger ◽  
Adrian Spoerri ◽  
Jabulani Ronnie Ncayiyana ◽  
...  

ObjectiveTo determine the spectrum of cancers in adolescents and young adults (AYAs) living with and without HIV in South Africa.DesignCross-sectional study with cancer records provided by the National Cancer Registry (NCR) and HIV records from the National Health Laboratory Service (NHLS).Setting and participantsThe NHLS is the largest provider of pathology services in the South African public sector. The NCR is a division of the NHLS. We included AYAs (aged 10–24 years) diagnosed with cancer by public health sector laboratories between 2004 and 2014 (n=8479). HIV status was obtained through record linkages and text mining.Primary and secondary outcomesWe determined the spectrum of cancers by HIV status in AYAs. We used multivariable logistic regression to describe the association of cancer in AYAs with HIV, adjusting for age, sex, ethnicity and calendar period. We imputed (post hoc) the HIV status for AYA with unknown HIV status.Results8479 AYAs were diagnosed with cancer, HIV status was known for 45% (n=3812). Of those whose status was known, about half were HIV positive (n=1853). AYAs living with HIV were more likely to have Kaposi’s sarcoma (adjusted OR (aOR) 218, 95% CI 89.9 to 530), cervical cancer (aOR 2.18, 95% CI 1.23 to 3.89), non-Hodgkin’s lymphoma (aOR 2.12, 95% CI 1.69 to 2.66) and anogenital cancers other than cervix (aOR 2.73, 95% CI 1.27 to 5.86) than AYAs without HIV. About 44% (n=1062) of AYAs with HIV-related cancers had not been tested for HIV.ConclusionsTargeted HIV testing for AYAs diagnosed with cancer, followed by immediate start of antiretroviral therapy, screening for cervical precancer and vaccination against human papilloma virus is needed to decrease cancer burden in AYAs living with HIV in South Africa.


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