scholarly journals Influence of ABO and Rhesus Blood Group on Blood Pressure and Hypertension in Bayelsa State

2021 ◽  
pp. 33-40
Author(s):  
S. O. Ojeka ◽  
D. V. Dapper ◽  
A. M. Egbejimi
Keyword(s):  
Blood Pressure ◽  
Blood Group ◽  
Study Design ◽  
Teaching Hospital ◽  
Niger Delta ◽  
Blood Groups ◽  
University Teaching ◽  
Abo Blood Groups ◽  
Cross Sectional ◽  
Significant Difference

Aim: This present study was carried out to ascertain the influences of ABO and Rhesus blood groups on blood pressure and hypertension among normotensive and hypertensive patients attending cardiologic clinic in Niger delta University Teaching Hospital, Okolobiri in Yenagoa Local Government Area of Bayelsa State Nigeria. Study Design: Cross sectional study design was adopted. Place and Duration of Study: The study was carried out in the Cardiology Clinics in the Niger Delta University Teaching Hospital (NDUTH), Okolobiri, Bayelsa State, from February 2020 to November 2020. Methodology: This study was carried out on 800 participants, consisting of 400 each of apparently healthy Normotensive and Hypertensive individuals. The blood pressures were determined using palpatory and auscultatory (stethoscope and sphygmomanometer) method in both control and hypertensive groups and their ABO and Rhesus blood groups were determined using the slide haemagglutination technique. Statistical analysis was done using SPSS statistical software to perform Chi-square test. Results: The frequency of the various blood groups was A-20.0%, B-16.8%, AB-13.3% and O-50.0% for the normotensive individuals and A-12.0%, B-15.5%, AB-17.8% and O-54.8%, for the hypertensive individuals. The frequency of ABO blood groups in both the normotensive and hypertensive group was therefore found to be O>B>A>AB. The prevalence of blood group O and rhesus O-ve was found to be  associated with elevated blood pressure and the development of hypertension while prevalence of blood group AB was found to be lowest in the same group, but was not significant statistically (p>0.05). There was no significant difference between systolic and diastolic blood pressure of different blood groups. Conclusion: Blood group O was found to be the most common blood group in our study. Blood group O- was also found to be more prone to hypertension. However, there was no statistically significant association between ABO blood groups and Hypertension.

scholarly journals KELL BLOOD GROUP ANTIGENS IN THE BLOOD DONORS ATTENDING BLOOD BANKS OF TERTIARY CARE HOSPITALS OF LAHORE, PAKISTAN.

2019 ◽  
Vol 26 (07) ◽  
pp. 1167-1171
Author(s):  
Sabeen Fatima ◽  
Mona Aziz ◽  
Sindhu Rehman ◽  
Maliha Asif ◽  
Naseem Akhtar ◽  
...  
Keyword(s):  
Blood Group ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Blood Groups ◽  
Blood Group Antigens ◽  
Abo Blood Groups ◽  
Cross Sectional ◽  
Significant Difference ◽  
Blood Banks ◽  
K Antigen

Introduction: Among the complications of blood transfusion, Hemolytic transfusion reactions (HTRs) and Hemolytic disease of the newborn (HDN) are particularly important. Literature reports frequency of HTRs and related mortality up to 1/76,000 and 1/1.8 million units transfused respectively. These hemolytic reactions are caused by incompatibility between the donor and recipient blood and in cases of HDN, due to feto-maternal incompatibility due to maternal antibodies attacking the fetal red cells. Anti-K antibody is the most common antibody encountered in blood banks after the ABO and Rh antibodies. So routine screening and matching of these blood antigens along with ABO and Rh can further reduce the risk of HTRs and HDN. Existing literature on Kell blood system reports varying frequency of K and k antigens among various populations. Objectives: The objectives of this study were to determine the prevalence of Kell blood group antigens in the blood donor population at Shaikh Zayed and Jinnah Hospitals Lahore and the association of Kell blood group antigens with different ABO blood groups of Lahore population. Study Design: It is a descriptive cross-sectional study. Setting: Research was conducted at the Blood banks of Sheikh Zayed Hospital, Lahore and Jinnah Hospital, Lahore. Period: 6 months after the approval of synopsis from 15/06/2015 to 15/12/2015. Material and Methods: This study included 192 donors; 96 from Sheikh Zayed Hospital, Lahore and 96 from Jinnah Hospital, Lahore. A written informed consent was taken from every donor. Kell blood group antigens K and k were determined. Results: There were 192 donors, 96 each from Shaikh Zayed Hospital, Lahore and Jinnah Hospital, Lahore. Out of these donors 186 (96.9%) were males and 6 (3.1%) were females. The most frequent ABO blood group antigen observed was B, which was seen in 82 (42.7%) donors, followed by O in 68 (35.4%), A in 36 (18.8%) and AB in 06 (3.1%) donors. Kell antigen k was found in 185 (96.3%) donors while K was found in 07 (3.6%) donors. When stratified, there was no statistically significant difference in the frequency of Kell antigens between genders (p=0.08) and ABO blood groups (0.09). The frequency of k antigen was higher among those with blood group B (43.2% vs. 17.8%) as compared to A, and the frequency of K antigen was higher among those with blood group A (42.8% vs. 28.5%) as compared to B, however, this was statistically insignificant. Conclusion: The frequency of k was observed to be 96.3%. It was higher in donors with antigen B while the frequency of K was found to be 3.6% and it was higher in donors with antigen A.

scholarly journals ABO and Rh Blood Groups and their Ethnic Distribution in a Teaching Hospital of Kathmandu, Nepal

2013 ◽  
Vol 52 (190) ◽  
Author(s):  
Lava Shrestha ◽  
Uzwali Malla ◽  
Narayan Bahadur Mahotra
Keyword(s):  
Blood Group ◽  
Teaching Hospital ◽  
Blood Groups ◽  
University Teaching ◽  
Cross Sectional ◽  
Transfusion Therapy ◽  
Blood Samples ◽  
Grouping Systems ◽  
Group B ◽  
Ethnic Distribution

Introduction: ABO and Rh blood group systems are the most important blood grouping systems from clinical aspect. Determination of blood group is important for blood transfusion therapy, medico-legal purposes, organ transplantation, settlement of paternity disputes etc.Methods: A cross-sectional descriptive study was carried out for a period of one year from 1st January 2011 to 31st December 2011 in blood bank of Tribhuvan University Teaching Hospital. All blood samples collected for blood group determination were included in the study. Blood group was determined by slide agglutination method using commercial antisera.Results: A total of 13568 blood samples were analyzed, 5123 (37.75%) were male and 8445 (62.25%) were female. Frequencies of blood groups A, B, AB and O were found to be 4034 (29.7%), 3665 (27.0%), 1114 (8.2%) and 4755 (35.1%). Frequencies of Rh positive and Rh negative blood groups were found to be 13200 (97.3%) and 368 (2.7%). Blood group O was common in Brahmin, Chhetri, Tamang, Lama, Gurung, Sherpa, Terai Brahmin, Muslim and Yadav ethnicities; blood group A was common in Newar, Rai, Magar, Limbu and Sanyasi ethnicitites; and blood group B was common in Tharu and Marwari ethnicities.Conclusions: Blood group O was found to be the most common blood group while AB was the rarest one. It was found that blood group O is the more common in Sherpa, Brahmin and Yadav; A in Limbu, Rai and Newar; and B in Tharu and Marwari ethnicities._______________________________________________________________________________________Keywords: ABO; blood group; ethnic distribution.

scholarly journals Correlation of ABO Blood Groups and Rh Factor with The Severity of Generalized Chronic Periodontitis: Across Sectional Study in Riyadh, Saudi Arabia

2019 ◽  
Vol 7 (4) ◽  
pp. 617-622 ◽  
Author(s):  
Diana Mostafa ◽  
Essam I. Elkhatat ◽  
Pradeep Koppolu ◽  
Muna Mahgoub ◽  
Esam Dhaifullah ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Blood Group ◽  
Chronic Periodontitis ◽  
Periodontal Diseases ◽  
Blood Groups ◽  
Blood Group Antigens ◽  
Abo Blood Groups ◽  
Sectional Study ◽  
Cross Sectional ◽  
Group I

BACKGROUND: The development of periodontal diseases depends on the presence of causative microorganisms, host immunity and risk factors. Although variability present among the types of periodontal diseases, all are represented to a shared interaction between host and bacteria. ABO blood groups are the most investigated erythrocyte antigen system. However, limited investigations have been conducted to explore the alliance between ABO blood groups and periodontal diseases. AIM: Our purpose was to explore any possible association between the severity of chronic periodontitis with ABO blood groups and Rh factor. METHODS: A cross-sectional study was carried out on 205 patients out of 1126 generalised chronic periodontitis patients (GCP) who were referred to Al-Farabi Colleges, Riyadh, Saudi Arabia. They were categorized into; group I (mild), group II (moderate) and group III (sever). RESULTS: The patients with blood group O were at a greater risk to develop GCP irrespective of its severity, followed by those with blood group A, B, and AB. The dispensation of the Rh factor in all groups exhibited a significantly greater distribution of Rh positive. CONCLUSION: Genetic factors such as ABO blood group antigens may act as a risk influencer that affects the progression and severity of the chronic periodontitis.

scholarly journals Association of ABO blood groups with presentation and outcomes of confirmed SARS CoV-2 infection: A prospective study in the largest COVID-19 dedicated hospital in Bangladesh

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0249252
Author(s):  
Reaz Mahmud ◽  
Mohammad Aftab Rassel ◽  
Farhana Binte Monayem ◽  
S. K. Jakaria Been Sayeed ◽  
Md Shahidul Islam ◽  
...  
Keyword(s):  
Blood Group ◽  
Blood Groups ◽  
Abo Blood Groups ◽  
Duration Of Symptoms ◽  
Presenting Symptoms ◽  
Blood Group A ◽  
Group I ◽  
Significant Difference ◽  
Group A ◽  
Group Ii

Background Globally, studies have shown conflicting results regarding the association of blood groups with SARS CoV-2 infection. Objective To observe the association between ABO blood groups and the presentation and outcomes of confirmed COVID-19 cases. Design, setting, and participants This was a prospective cohort study of patients with mild-to-moderately severe COVID-19 infections who presented in the COVID-19 unit of Dhaka Medical College Hospital and were enrolled between 01 June and 25 August, 2020. Patients were followed up for at least 30 days after disease onset. We grouped participants with A-positive and A-negative blood groups into group I and participants with other blood groups into group II. Results The cohort included 438 patients; 52 patients were lost to follow-up, five died, and 381 completed the study. The prevalence of blood group A [144 (32.9%)] was significantly higher among COVID-19 patients than in the general population (p < 0.001). The presenting age [mean (SD)] of group I [42.1 (14.5)] was higher than that of group II [38.8 (12.4), p = 0.014]. Sex (p = 0.23) and co-morbidity (hypertension, p = 0.34; diabetes, p = 0.13) did not differ between the patients in groups I and II. No differences were observed regarding important presenting symptoms, including fever (p = 0.72), cough (p = 0.69), and respiratory distress (p = 0.09). There was no significant difference in the median duration of symptoms in the two group (12 days), and conversion to the next level of severity was observed in 26 (20.6%) and 36 patients (13.8%) in group I and II, respectively. However, persistent positivity of RT-PCR at 14 days of initial positivity was more frequent among the patients in group I [24 (19%)] than among those in group II [29 (11.1%)]. Conclusions The prevalence of blood group A was higher among COVID-19 patients. Although ABO blood groups were not associated with the presentation or recovery period of COVID-19, patients with blood group A had delayed seroconversion.

scholarly journals DISTRIBUTION OF ABO AND RH (D) BLOOD GROUPS AMONG BLOOD DONORS IN DISTRICT MARDAN, PAKISTAN

1969 ◽  
Vol 3 (2) ◽  
pp. 318-322
Author(s):  
MUHAMMAD KHALID ◽  
NAILA ASLAM ◽  
MUHAMMAD SIYAR ◽  
RASHID AHMAD
Keyword(s):  
Blood Group ◽  
Blood Donors ◽  
Local Community ◽  
Healthy Adult ◽  
Blood Groups ◽  
Abo Blood Groups ◽  
Cross Sectional ◽  
Group B ◽  
Abo Blood Grouping ◽  
Blood Grouping

OBJECTIVE: To find out the distribution of ABO and Rh (D) blood groups among blood donors in districtMardan and to help transfusion services in the area.STUDY DESIGN: Cross sectional descriptive study.MATERIALS AND METHODS: The study was conducted in DHQ Hospital Mardan from 1st January2012 to 31st December 2012. A total of 2893 healthy adult, blood donors (both volunteer and directed) fromdistrict Mardan were included. Two ml of blood anti-coagulated with EDTA was taken and both ABO andRh (D) blood groups were determined using commercially available anti-sera of Biolaboratories. Thedistribution ofABO and Rh blood groups in the local community were then calculated.RESULTS: Among ABO blood groups “ B” (27.97%) was the most prevalent, followed by “0” (27.93%),“ A” (24.75%) and “ AB” (19.36%). Group Rh positive (94.30%) was more prevalent than Rh negative(5.70%). Similarly 0+ve (26.65%) was most frequent followed by B+ve (26.17%), A+ve (23.16%), AB+ve(18.32%), B've(1.80%),Ave(l.59%),O ve( 1.28%) and ABve( 1.04%).CONCLUSION: Blood group 'B' was most frequent among the ABO blood groups and Rh (D) positiveamong Rh blood groups while0+vewas the most frequent blood group in the study population.KEYWORDS: ABO Blood grouping, Rh (D) blood grouping, Mardan.

scholarly journals Association of Pre-hypertension with blood groups in young population.

2019 ◽  
Vol 26 (11) ◽  
pp. 1820-1824
Author(s):  
Benash Altaf ◽  
Shireen Jawed ◽  
Fakiha Behram ◽  
Zeeshan Ali Khan ◽  
Shakeela Naz
Keyword(s):  
Blood Group ◽  
Demographic Data ◽  
Cross Sectional Study ◽  
Blood Groups ◽  
P Value ◽  
Continuous Variables ◽  
Cross Sectional ◽  
Blood Group A ◽  
Significant Difference ◽  
Group A

Objectives: Pakistan has highest mortality rate due to hypertension and its complications. Hypertension is a squealed of Pre- hypertension which is believed to start at adolescent and continue to adulthood. Association of blood group with hypertension is evident but still hypothesized. This study aims to find the frequency of prehypertension and its association with blood group. Study Design: Cross sectional study. Setting:  Aziz Fatimah Medical and Dental College, Faisalabad. Period: 15 March’18 to 15 Sep’18. Material and Methods:  It was comprised of in comprised of 100 MBBS students. Demographic data including age, weight, height, waist and hip circumference, and BMI was determined. Blood group was determined with help of conventional slide method. Blood pressure was measured by auscultatory method. Data was analyzed by using SPSS 21. Continuous variables are given in mean and standard deviation. Categorical data was given in frequency and percentages. P value≤ 0.05 is taken as significant. Results: Out of 100 participants most common blood group was group ‘O’ (43%) followed by B (35 %) and AB (13%) and A (9%).36% of total population was pre-hypertensive and 64% were normotensive. Prehypertension is most commonly found in blood group ‘A’ (77%) followed by blood group ‘O’ (46.5%). Significant difference was found in means of SBP (p value= 0.001*) and DBP (p value= 0.000*) among the various blood groups. Conclusion: Most common blood group in studied population was ‘O’ although hypertension was most commonly observed in blood group A followed by ‘O’.

scholarly journals Acute Myocardial Infarction and its association with ABO blood group in Pakistani population

2020 ◽  
Vol 24 (2) ◽  
pp. 103-107
Author(s):  
Imran Iftikhar ◽  
Hamid Sharif Khan ◽  
Adeel Ur Rehman
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Informed Consent ◽  
Blood Group ◽  
Blood Groups ◽  
Abo Blood Group ◽  
Abo Blood Groups ◽  
Pathology Laboratory ◽  
Cross Sectional ◽  
Pakistani Population

OBJECTIVE: To determine the frequency of ABO blood groups among patients with acute myocardial infarction in the Pakistani population STUDY DESIGN: Cross-sectional study PLACE AND DURATION OF STUDY : Department of Interventional Cardiology, Rawalpindi Institute of Cardiology, Rawalpindi, from May 2015 to November 2015. METHODOLOGY: A total of 250 subjects with acute myocardial infarction were included in the study. The study was explained to the patients and informed consent taken. All patients underwent 12 lead electrocardiography using Mortara instrument ELI 250 and were analyzed by a single trained reader unaware of the patients’ blood group. Cardiac troponin levels were assessed at least three hours after the onset of symptoms. The ABO blood group was assessed by using the standard slide agglutination method in the hospital pathology laboratory and verified by the principal investigator. The data was collected on a pre-tested questionnaire by the investigator after taking informed consent from the patient. RESULTS: In our study, the mean age of patients was 57.3 years. 36.4% were between 18-50 years of age while 63.6%were between 51-80 years of age. 79.2% were male and 20.8% were females. Frequency of ABO blood groups among patients with acute myocardial infarction in our study population was recorded as 28.8% with O +ve , 26% with B+ve, 18.4% with A+ve, 13.2% with AB +ve, 5.6% with A-ve, 4.4% with B-ve, 3.2% with O-ve and 0.4% with AB -ve CONCLUSION: We concluded that the frequency of acute myocardial infarction in our population is higher among patients having blood group O+ve followed by B+ve blood group.

Anti-Von Willebrand Factor Antibody Is Responsible for Lower Levels of Plasma vWF in Blood Group O Individuals.

Blood ◽  
2004 ◽  
Vol 104 (11) ◽  
pp. 254-254 ◽  
Author(s):  
Letian Dai ◽  
Shawn Cotton ◽  
Alistair Macartney ◽  
Geoffrey Savidge ◽  
Anwar Alhaq
Keyword(s):  
Blood Group ◽  
Blood Groups ◽  
Bleeding Tendency ◽  
Plasma Samples ◽  
Abo Blood Groups ◽  
Acquired Von Willebrand Syndrome ◽  
Significant Difference ◽  
Group A ◽  
Group B ◽  
Von Willebrand

Abstract Plasma levels of vWF are known to be influenced by ABO blood groups, although the mechanism remains unresolved. Group O individuals have a significantly lower level of plasma vWF than those with group A, B or AB. This relative lower level of plasma vWF may result in a bleeding tendency and a shorter half-life of infused factor VIII in group O individuals. The formation of immune complexes between vWF and autoantibodies has been shown to accelerate vWF clearance from plasma in acquired von Willebrand syndrome. However, so far no evidence has been presented that the presence of autoantibodies against vWF is involved in lowering plasma level of vWF in group O individuals. In the present study, plasma samples were obtained from 199 healthy blood donors of blood group O (50), group A (50), group B (49), and group AB (50). A time-resolved fluorescence immunoassay (TRFIA) was developed to detect anti-vWF IgG in plasma samples. Briefly, 100 μl of diluted plasma was loaded on to duplicated vWF-coated and untreated control wells of a microplate. After incubation and washing, 100 μl of Europium-labeled anti-human IgG conjugate (1:500 dilution) was added to the plate to detect vWF IgG. The time-delayed fluorescence was then measured with a Victor microplate reader (PerkinElmer, Turku, Finland). The fluorescence counts of the control wells were subtracted from those of the vWF-coated wells. The results show that anti-vWF IgG was present in all four blood groups (Table 1). Of these blood groups, group O had the highest anti-vWF IgG level with 9.8 x 105 fluorescence counts, which was 2.7- to 3.5-fold higher than that of group A, B or AB. There was a significant difference in the anti-vWF IgG levels between group O and the rest of group A, B or AB. Quantitative analysis of plasma vWF by ELISA showed that the concentration of plasma vWF of group O was 29 to 35% lower than that of group A, B or AB (Table 1). These results suggest that TRFIA is a sensitive assay for detection of anti-vWF IgG in plasma samples, and the presence of the high level of anti-vWF Ig G in group O individuals may be responsible for lowing plasma vWF by acceleration of vWF clearance. Anti-VWF IgG levels and vWF concentrations in diffeent ABO blood groups Group O (n=50) Group A (n=50) Group B (n=49) Group AB (n=50) Data are presented as a mean ± SD. *P<0.01 compared with group A, B or AB. +P<0.01 compared with group A,B or AB. Anti-vWF IgG (x 105 Fluorescence counts) 9.8 ± 6.9* 2.8 ± 2.8 3.1 ± 3.0 3.6 ± 3.5 Concentration of vWF (% of normal controls) 116 ± 42+ 165 ± 46 165 ± 42 179 ± 49

Study of distribution of ABO blood groups in ß-thalassemia patients

2017 ◽  
Vol 5 (8) ◽  
pp. 3479 ◽  
Author(s):  
Pranoti A. Sinha ◽  
Sachin H. Mulkutkar ◽  
J. B. Bhavani
Keyword(s):  
Blood Group ◽  
Late Onset ◽  
Blood Groups ◽  
Beta Thalassemia ◽  
Abo Blood Groups ◽  
Thalassemia Patient ◽  
Cross Sectional ◽  
Globin Chains ◽  
Institutional Ethics ◽  
History Of

Background: ß-thalassemia is an inherited hematological disorder caused by reduced or absent synthesis of ß globin chains of the hemoglobin which causes hemolysis and impair erythropoiesis. Affected children thus require regular lifelong blood transfusions. Blood group is one of the important and comparatively known parameter today which exhibits a strong correlation with some common diseases like cardiovascular diseases, gastric cancer, HIV infection etc. Aim of this study hence was to study relation between ABO blood groups and ß-thalassemia and to study complications in each blood groups to make it easy to predict the type of population which is more prone or resistant to ß-thalassemia for understanding the regional demand of rare blood groups and to tide over the demands.Methods: This was a cross sectional, single centric, open labeled, observational study in which 100 patients of ß-thalassemia were screened for their ABO blood groups after permission from institutional ethics committee and informed consent from the patient.Results: Most common blood group in ß-thalassemia patient is O +ve. Post-disease complication is commonly seen with B +ve. Early onset of beta-thalassemia is seen in A +ve and B +ve. Late onset is seen with O +ve. Severity more with B –ve while O +ve shows disease in less severe form.Conclusions: On analysis, it was found that the most common blood group getting affected by the disease ß-thalassemia is O +ve with the same people having higher chances of family history of the same disease. Within the family members who have the positive history of the disease, most common was O +ve blood group again.

scholarly journals Association of ABO Blood Group and Body Mass Index: A Cross-Sectional Study from a Ghanaian Population

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Samuel Smith ◽  
Isaac Okai ◽  
Chrissie Stansie Abaidoo ◽  
Emmanuel Acheampong
Keyword(s):  
Body Mass Index ◽  
Blood Group ◽  
Body Mass ◽  
Cross Sectional Study ◽  
Blood Groups ◽  
Blood Type ◽  
Abo Blood Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Significant Difference

ABO blood group and body mass index (BMI) have individually been appraised as risk factors for certain diseases. From statistical perspective, it may be important to examine the relationship between the ABO blood antigen and BMI. This cross-sectional study involved 412 participants aged 18 to 46 at the Kwame Nkrumah University of Science and Technology (KNUST), Kumasi. Weight and height of participants were measured for BMI calculation; blood group determination was done using antisera. Blood group O was the most prevalent (51.2%), while Rhesus-positive individuals constituted 90.3%. 6.3% of the participants were obese, while 18.7% were overweight. There was significant (p=0.006) higher prevalence of obesity in females (10.3%) than in males (3.4%). The study did not observe any significant difference by association of ABO blood group with gender (p=0.973), BMI (p=0.307), or Rhesus status (p=0.723). Regarding gender (p=0.400) and BMI (p=0.197), no statistically significant difference was observed between Rhesus blood groups. The prevalence of overweight, obesity, blood type O, and rhesus positive observed among students in this study is largely similar to what has been reported in published studies in Ghana and from other countries. Overweight and obesity were not associated with ABO blood groups or Rhesus in this study.

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