scholarly journals Evaluation of C-reactive Protein Levels in the Saliva of Covid Recovered Patients

Author(s):  
Soorya Ganesh ◽  
Palati Sinduja ◽  
. Priyadharshini ◽  
V. Meghashree

Introduction: The acute phase reactant synthesized by the liver. CRP is an annular (ring- shaped) metameric protein set up in plasma, whose circulating immersion rise in response to inflammation. The idea of the study is to estimate the C-reactive protein situations in the salivary samples of COVID- 19 recovered cases and healthy controls. Materials and Methods: An experimental study on salivary samples of COVID recovered cases. The study was non-invasive and easy to perform without important vexation to cases. The samples were acquired from cases who came to the clinics of Saveetha Dental College and Hospitals. An aggregate of 20 saliva samples was collected from recruited cases 10 of whom were healthy controls and 10 were collected from cases who had made complete recovery from COVID infection. Results: C-reactive protein (CRP) could be generally used as a biomarker of systemic inflammation, routinely measured in serum blood samples. Still salivary samples offer a non-invasive and simply accessible preference which might upgrade point of care (POC) testing for inflammation. This study illustrates the group of healthy controls and COVID recovered cases. Conclusion: Within the limitations of our study, we were capable to interpret the difference of CRP levels between COVID recovered cases and healthy individualities.

2016 ◽  
Vol 33 (S1) ◽  
pp. S337-S337
Author(s):  
M. Pantovic Stefanovic ◽  
B. Dunjic-Kostic ◽  
M. Lackovic ◽  
A. Damjanovic ◽  
A. Jovanovic ◽  
...  

IntroductionImmune alterations are believed to be an important part in etiopathogenesis of affective disorders. However, it is not clear if the altered immune mediators are related to distinct disorders or particular psychopathology.AimsThe aim of our study was to explore the differences in C-reactive protein levels (CRP) between euthymic BD patients and healthy controls, as well as to explore the relationship between CRP and lifetime presented psychopathology within BD.MethodsThe study group consisted of 83 patients diagnosed with BD, compared to the healthy control group (n = 73) and matched according to age, gender, and body mass index (BMI). Lifetime psychopathology has been assessed according to predominant polarity as well as previous history of suicide attempts and psychotic episodes.ResultsThe CRP levels were significantly higher in BD patients when compared to healthy controls. After covarying for confounders, we observed that CRP levels, in euthymic BD patients, were related to number of previous suicide attempts, but not other indicators of lifetime psychopathology.ConclusionsBD patients per se, and particularly those with more suicide attempts, are more likely to present with proinflammatory state, even when in remission. Previous history of suicide attempts could bear specifically vulnerable endophenotype within BD. Systemic, longitudinal monitoring of the course of illness, and potential inflammatory mediators that underlie its systemic nature is warranted.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2021 ◽  
Vol 9 (09) ◽  
pp. 106-107
Author(s):  
Susmitha Vasanth Pentyala ◽  
Abhilash Tadiboina

Cerebrovascular accident, which has considerable mortality and morbidity,deservesattention towards its prevention. The first lines of defense in stroke prevention are detecting and adequately treating manageable risk factors, C-Reactive protein, an acute phase reactant is an indicator ofunderlying systemic inflammation and a novel marker for atherothrombotic disease. Present study is an attempt to study the levels of C-Reactive protein in acute thromboembolic stroke and to correlate between serum C Reactive protein levels and lipid profile in acute ischemic stroke.


Animals ◽  
2020 ◽  
Vol 10 (6) ◽  
pp. 1042
Author(s):  
Yoo-Ra Cho ◽  
Ye-In Oh ◽  
Gun-Ho Song ◽  
Young Jun Kim ◽  
Kyoung-Won Seo

We performed this study to characterize the difference between the inflammatory and non-inflammatory status in diseased dogs by measuring salivary C-reactive protein (CRP) levels. In addition, we assessed whether a correlation exists between CRP levels in saliva and those in serum. CRP levels were measured in 32 client-owned dogs, which were then divided into inflammation and non-inflammation groups based on the serum CRP level. The salivary CRP level was higher in the inflammation group than in the non-inflammation group (p < 0.05). Furthermore, there was a positive correlation between the salivary and serum CRP levels (R = 0.866, p < 0.001). These data suggest that canine salivary CRP measurements can effectively and non-invasively detect an inflammatory state in dogs.


2021 ◽  
Author(s):  
elena chertok ◽  
Guy Dori ◽  
Naama Schwartz ◽  
Ori Cheshin ◽  
Ronit Nitzan ◽  
...  

Abstract Background.C-reactive protein (CRP) is an acute phase reactant protein synthesized in the liver. Human body proportions, such as body mass index (BMI), may affect CRP levels during infection. This study was carried out to investigate the relationship between CRP and BMI in obese versus non- obese patients hospitalized with common acute infections.MethodsA total of 445 patients admitted with diagnoses of pneumonia, urinary tract infections and cellulitis were included in the statistical analysis. Among them, 287 were diagnosed with pneumonia, 80 with UTIs and 78 with cellulitis. Each group was also divided according to their BMI. (< or ≥ 30 kg/m2). We gathered data for serial CRP measurements performed on day 0-1, 1-3, and 4-6 of hospitalization as well as BMI levels for all patients. Other markers of acute inflammation, including WBC, fibrinogen level, LDH, as well as albumin level and GFR were recorded.ResultsOverall, we found no difference in CRP levels in patients with or without obesity throughout the duration of their hospitalization. There was a trend of elevated CRP level at the beginning of hospitalization in the group with BMI≤30 (p=0.06). No correlation was found between CRP levels and BMI at the points of measurements during hospitalization in the three study groups.ConclusionCRP levels do not correlate with BMI and with other biomarkers of inflammation in patients hospitalized with acute infectious diseases.


Author(s):  
Cihan Adanas ◽  
Sezai Ozkan ◽  
Canan Demir

Abstract Objective: To compare the levels of ischemia modified albumin between osteomyelitis patients and healthy controls. Method: The cross-sectional prospective study was conducted at Van Yüzüncü Y?l University, Van, Turkey, from May 2018 to May 2019, and comprised inpatients diagnosed with osteomyelitis, and healthy controls. Serum IMA concentrations were determined spectrophotometrically at 470nm wavelength. Serum ischemia modified albumin levels were measured and compared between the patients and the controls. Data was analysed using SPSS 20. Results: Of the 77 subjects, 37(48%) were patients and 40(52%) were controls. Serum ischemia modified albumin level in patients was significantly higher than controls (p<0.05). There was a significant correlation between ischemia modified albumin and C-reactive protein levels (p<0.05). Conclusion: Serum ischemia modified albumin level in patients was significantly higher than controls (p<0.05). Key Words: Osteomiyelitis, Ischemia-modified albumin, Receiving operation curve, Biomarker, C-reactive protein. Continuous...


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