scholarly journals Innocuous Lesions and Not so Innocuous Lesions of the Skin and Soft Tissue

2021 ◽  
pp. 1-7
Author(s):  
Nayantara Srikanth ◽  
K. Nithin Diwagar ◽  
B. S. Padmapriya ◽  
Ganthimathy Sekhar
Keyword(s):  
Soft Tissue ◽  
Histopathological Examination ◽  
Histopathological Diagnosis ◽  
Cystic Lesions ◽  
Histopathological Features ◽  
Medical College ◽  
Trichilemmal Cyst ◽  
Mucous Retention Cyst ◽  
Appropriate Therapy ◽  
One Year

Background: Cystic lesions of the skin and soft tissue are often neglected and thought to be innocuous or harmless. These lesions need to be excised to exclude malignancy. The lesions may present in unusual sites and may also be of infective origin. Thus, there is an urgent need to determine the prevalence and identify the histopathological features of the cystic lesions as the innocuous appearing lesions may actually not be so innocuous. In addition, it is the histopathological features that determine the treatment modality. Aim: To determine the features and prevalence of the types of cysts in skin and soft tissue. Materials and Methods: A retrospective study of the cystic lesions of the skin and soft tissue was conducted. The records from the Department of Pathology, Saveetha Medical College were retrieved and reviewed for patients with cystic lesions of the skin and soft tissue over a one year period extending between January 2019 and December 2019. The records were examined for the following data : age, sex, type of lesion, clinical and histopathological diagnosis. Results: In all 109 cases with skin and soft tissue swellings were analyzed. Among these 53 were males and 56 were more females reported (51 %) of cystic swellings as compared to males (48%). Cystic lesions were most commonly encountered in the age group of 18 to 40 years, which suggests that there may be a role for trauma or occupation related occurrence. A variety of cysts were encountered such as epidermoid cysts (70%), Trichilemmal cyst (7%), and Ganglion (7%).Phaeohyphomycotic cyst, mucous retention cyst, hemangioma and pilomatrixoma. Epidermal cysts were more frequently encountered in males (54%) than females (46%).Most lesions occurred in the back. Conclusion: Epidermal cysts may frequently be associated certain syndromes, hence it is important to evaluate these cysts. In addition phaeohyphomycotic cysts may be mistaken for Ganglion, so histopathological examination is necessary to initiate appropriate therapy.

scholarly journals Histopathological Analysis of Endometrial Biopsy in Gandaki Medical College Teaching Hospital, Pokhara, Nepal

2019 ◽  
Vol 12 (1) ◽  
pp. 25-30
Author(s):  
B Parajuli ◽  
G Pun ◽  
S Ranabhat ◽  
S Poudel
Keyword(s):  
Histopathological Examination ◽  
Hydatidiform Mole ◽  
College Teaching ◽  
Histopathological Diagnosis ◽  
Age Group ◽  
Medical College ◽  
Dilatation And Curettage ◽  
Partial Mole ◽  
Proliferative Endometrium ◽  
The Common

Objective: To study the spectrum of histopathological diagnosis of endometrial lesions and their distribution according to age. Methods: All the endometrium samples obtained by the procedure of dilatation and curettage and hysterectomy sent for histopathological examination at Pathology Department of Gandaki Medical College Teaching Hospital, Pokhara, Nepal. The study duration was total 12 months ranging from July 2016 to June 2017. All the endometrial samples were processed, sectioned at 4 - 6 μm and stained with routine H & E stain. Patient’s data including age, sex, procedure of the biopsy taken and histopathological diagnosis were noted. A pathologist, using Olympus microscope, reported the slides. Cases were reviewed by a second pathologist whenever necessary. Results: A total of 128 cases were studied. The most common histopathological diagnosis was proliferative endometrium (28.9%) followed by disorder proliferative endometrium (15.65%). Most of the patients were in age group 36 - 45 years comprising 32.03%. Hydatidiform mole comprised of 7.03% and among Hydatidiform mole, partial mole was more common. Dilatation and curettage (82.8%) was the common procedure in compare to hysterectomy for the evaluation of endometrial lesions. Conclusions: In this study, we observed a variety of endometrial lesions. Most of them are benign; among benign, proliferative endometrium was the common histopathological diagnosis followed by disorder proliferative endometrium. Most common presenting age group was found to be at 36 - 45 years. In evaluation of hydatidiform mole, partial mole was more frequent in compare to complete mole. Conventional dilatation and curettage is the preferred method in developing countries with limited resource to screen endometrial lesion and therefore biopsy should be sent for histopathological examination. Thus histopathological examination of routinely stained hematoxylin and eosin is readily available and widely accepted standard technique for evaluation of the endometrial lesions.

scholarly journals HYSTERECTOMIES

2011 ◽  
Vol 18 (01) ◽  
pp. 46-50
Author(s):  
QAMAR-UR- NISA ◽  
HABIB ULLAH ◽  
TANWEER AHMED SHAIKH ◽  
Miss Hemlata ◽  
Fatima Memon ◽  
...  
Keyword(s):  
Coming Out ◽  
Histopathological Examination ◽  
Medical College Hospital ◽  
Uterovaginal Prolapse ◽  
Histopathological Diagnosis ◽  
College Hospital ◽  
Medical College ◽  
Obstetrics And Gynaecology ◽  
Chronic Cervicitis ◽  
Made In

Objective: To audit indications and histopathological diagnosis of hysterectomies performed at Muhammad Medical College hospital, Mirpurkhas. Study Design: Retrospective study. Place and Duration of Study: Department of Obstetrics and Gynaecology and Department of Pathology, Muhammad Medical College Hospital, Mirpurkhas Sindh from January to December 2008. Methodology: Data regarding symptoms and indications of hysterectomies performed during this year were collected from files and patient records. Histopathological reports of those patients were collected from department of pathology. The results were analyzed by percentages. Results: A total of 145 hysterectomies were performed in 2008. Mean age of patients was 45years ranging from 35-60 years and parity ranges from 4 – 10. Most common presenting complaints were excessive menstrual blood loss in 97(67%) patients, followed by some thing coming out of vagina 28(19%). Most common pre-operative diagnosis of fibroid was made in 44 (33%) followed by uterovaginal prolapse in 28(19%) and dysfunctional uterine bleeding (DUB) in 18(12%) of patients. Regarding histopathological diagnosis chronic cervicitis was the most commonly diagnosed pathology in 45 (31%) followed by fibroid in 25(17%) cases. Conclusions: A yearly audit should be conducted in every institute to collect data and to analyze the pattern of indication and lesions found on histopathological examination. 

Embryonal Rhabdomyosarcoma of the Testis

2020 ◽  
Vol 23 (2) ◽  
pp. 98-99
Author(s):  
Ayesha Rahman ◽  
SM Syeed Ul Alam ◽  
Salma Sultana
Keyword(s):  
Soft Tissue ◽  
Lymph Nodes ◽  
Mesenchymal Cells ◽  
Embryonal Rhabdomyosarcoma ◽  
Histopathological Diagnosis ◽  
Soft Tissue Tumour ◽  
Tissue Tumour ◽  
Scrotal Swelling ◽  
Testicular Malignancy ◽  
One Year

Rhabdomyosarcoma (RMS), arising from mesenchymal cells, is the most common soft tissue tumour in children and accounts for up to half of all sarcomas. We present a case of a 15 year old male presented with gradually increasing right sided scrotal swelling for last one year. The patient was later diagnosed as right testicular malignancy with metastasis in abdominal lymph nodes and lungs. Inguinal orchidectomy was performed and final histopathological diagnosis was embryonal rhabdomyosarcoma of right testis. Journal of Surgical Sciences (2019) Vol. 23(2): 98-99

scholarly journals Clinicopathological study of bacterial lesions in a tertiary care hospital

2021 ◽  
Vol 9 (7) ◽  
pp. 2072
Author(s):  
Sonti Sulochana ◽  
Jalavadi Rahul Siddartha
Keyword(s):  
Bacterial Infections ◽  
Tertiary Care Hospital ◽  
Histopathological Examination ◽  
Tertiary Care ◽  
Granulomatous Inflammation ◽  
The Body ◽  
Histopathological Diagnosis ◽  
Care Hospital ◽  
H Pylori ◽  
One Year

Background: The incidence of bacterial lesions has been on the rise over the decades. In our study, we assessed and studied the spectrum of bacterial lesions retrospectively for one year and their clinicopathological correlation which was diagnosed on histopathological examination in a tertiary health care center.Methods: The present study (retrospective) has been done to analyse the incidence of bacterial infections obtained in the histopathology laboratory and study its clinical correlation and significance. Clinical details of the cases were accessed from biopsy requisition forms and included tissues from various sites in the body. Special stains were done which included acid fast bacilli (AFB), Fite Farraco (FF) stain and gram stain for the identification of bacteria.Results: A total of 318 cases including 288 H. pylori infections, granulomatous inflammation 18, Hansen disease 9 and 3 actinomycosis infections.Conclusions: The histopathological diagnosis of bacterial lesions are of utmost importance as it is more reliable than culture in circumstances of reduced tissue availability. Early reporting is extremely necessary to reduce complications related to bacterial lesions.

Eosinophil Count Variation among Histopathological Features of Appendectomy Specimens at Birat Medical College Teaching Hospital

2020 ◽  
Vol 5 (2) ◽  
pp. 1104-1109
Author(s):  
Santosh Upadhyaya Kafle ◽  
Mrinalini Singh ◽  
Neeta Kafle ◽  
Amrita Sinha
Keyword(s):  
Teaching Hospital ◽  
Eosinophil Count ◽  
Histopathological Examination ◽  
Demographic Data ◽  
Age Groups ◽  
College Teaching ◽  
Histopathological Diagnosis ◽  
Cross Sectional ◽  
Gold Standard Method ◽  
Medical College

Introduction: The histopathological examination of appendectomy specimens is the gold standard method for diagnosis. The presence of eosinophil besides other inflammatory cells like neutrophils and mature lymphocytes within different histological layers of appendectomy specimens are common findings for labeling it under various groups. This finding supports the assumption that appendicitis is triggered by Type 1 hypersensitivity reaction.  Objective: To evaluate the eosinophil count variation in appendectomy specimens in patients with the clinical diagnosis of appendicitis.  Methodology: This is a cross sectional hospital based study of 144 appendectomy specimens obtained in Department of Pathology, Birat Medical College Teaching Hospital from January 2019 to December 2019. Socio-demographic data, association of histopathological patterns with age groups, gender and eosinophil count in various histopathological groups was compared and cross-tabulated using SPSS version 16.  Result: Among 144 appendectomy specimens, male gender (50.70%) of 15-24 years age group (36.80%) was predominant. The commonest histopathological diagnosis was acute appendicitis (31.25%) with highest eosinophil count in all of its histological layers. The association of various histopathological patterns with age groups and gender were not statistically significant, whereas it revealed statistically significant correlation between eosinophil counts in all histological layers.  Conclusion: Findings suggest that the eosinophil count variation in the entire histological layers correlate well among different histopathological patterns of appendectomy specimens. This reflects the high diagnostic value of evaluating the eosinophil count in appendectomy specimens. 

scholarly journals Histopathological Audit of 373 Nononcological Hysterectomies in a Teaching Hospital

2014 ◽  
Vol 2014 ◽  
pp. 1-5
Author(s):  
Kanwardeep Kaur Tiwana ◽  
Sarita Nibhoria ◽  
Tanvi Monga ◽  
Richa Phutela
Keyword(s):  
Preoperative Diagnosis ◽  
Health Care Services ◽  
Histopathological Examination ◽  
Treatment Modalities ◽  
Common Finding ◽  
Kappa Statistics ◽  
Histopathological Diagnosis ◽  
Care Services ◽  
One Year

Hysterectomy, the most common gynecological surgery, provides a definitive cure to various diseases like DUB (dysfunctional uterine bleeding), leiomyoma, adenomyosis, chronic pelvic pain, prolapse, and malignancy. However, with advent of effective medical and conservative treatment modalities for nononcological causes it is now posing question mark on justification of hysterectomy. Therefore, an audit is required to assess the correlation between preoperative diagnosis and histopathological examination of specimen for justification of the procedure. In this study over period of one year (April 2013 to March 2014) 373 hysterectomies specimens were received in the department of pathology for nononcological causes. The age of patients ranged from 22 to 85 years with mean 45±9.2 years. All cases were divided into five categories on the basis of age and audit was done. In this study the most common finding was leiomyoma (43.7%) followed by adenomyosis (19.3%). Almost 50% of hysterectomies causes were justified as preoperative diagnosis matched with histopathology. Cohen kappa statistics were used to measure agreement between preoperative and postoperative histopathological diagnosis which was found to be fair with κ value being 0.36. This study highlights that regular audit of surgeries can help improve quality of health care services and provide safe conservative option to patients.

scholarly journals Evaluation of neck swelling by cytological and histopathological examination

2012 ◽  
Vol 18 (1) ◽  
pp. 23-29
Author(s):  
Md Mahmudul Huq ◽  
Mohammad Idrish Ali ◽  
SM Nazmul Huque ◽  
KM Nurul Alam ◽  
Md Abdus Sattar ◽  
...  
Keyword(s):  
Histopathological Examination ◽  
Follicular Adenoma ◽  
Nodular Goiter ◽  
Metastatic Carcinoma ◽  
Medical College Hospital ◽  
Histopathological Diagnosis ◽  
Neck Swelling ◽  
College Hospital ◽  
Female Ratio ◽  
Medical College

Objective: In this study 50 patients of neck swelling were studied to compare the findings with clinical diagnosis and histopathological report for its diagnostic reliability.Methods: This cross sectional study was done in ENT Department of Sher-E-Bangla Medical College Hospital, Barisal, Bangabandhu Sheikh Mujib Medical University and Dhaka Medical College Hospital, Dhaka from July 2006 to December 2006. Fine needle aspiration cytology, MRI, CT scan, and histopathological examination of postoperative specimen of neck swelling, analyzed data presented by various tables, graphs and figures.Results: In the present series 50 cases of neck swelling were studied. Out of these 50 cases 19 were male and 31 were female. The male, female ratio was 1:1.63. Age range was 4 – 60 years with maximum frequency in the 4th decade with the 3rd and 2nd in the following suit. Most of the patient was poor. Clinical, cytological and histopathological diagnosis was available in all the cases. The three sorts of diagnoses were compared with each other. Histopathologically 12 cases were tubercular lymphadenopathy, 12 cases were nodular goiter, 5 cases were Metastatic carcinoma, 5 were thyroid carcinoma and another 5 cases were lymphoma, Rest were benign, congenital and nonspecific inflammatory conditions. Correct diagnosis was made by FNAC in 45 cases. In the rest 5 cases smear were unsatisfactory in 2 cases and gives inconclusive result, remaining 3 were follicular neoplasmand no definitive result were made which were subsequently diagnosed by histopathological examination as a follicular adenoma in 1 and follicular carcinoma in 2. Sensitivity of FNAC in the diagnosis of neck masses were found 91% for tuberculosis, 100% for metastatic carcinoma and also for salivary gland tumour. In case of nodular goiter sensitivity was 92%. But it is only 60% sensitive in case of thyroid malignancy, as FNAC can not demarcate clearly between follicular adenoma and follicular cell carcinoma. But its accuracy in diagnosing papillary carcinoma of thyroid was 100%.Conclusion: FNAC can reduce substantially the need of open biopsy for histopathological examination. Accuracy of FNAC will be improved with relevant information provided by clinicians.DOI: http://dx.doi.org/10.3329/bjo.v18i1.10410  Bangladesh J Otorhinolaryngol 2012; 18(1): 23-29

scholarly journals Clinico-Pathological Correlation in the Classification of Leprosy

2019 ◽  
Vol 7 (2) ◽  
pp. 21-24
Author(s):  
Anuj Poudel ◽  
Anita Shah ◽  
Sulochana Khatiwada ◽  
Ashok Samdurkar
Keyword(s):  
Histopathological Examination ◽  
Clinical Information ◽  
Histopathological Diagnosis ◽  
Medical Sciences ◽  
Major Health ◽  
Histopathological Features ◽  
Clinical Presentations ◽  
Skin Biopsies ◽  
Bacterial Index

INTRODUCTION:- Leprosy is one of the major health problems in Nepal, caused by Mycobacterium leprae. Histopathological examination is considered as important tool for proper classification of the disease. This study was carried out to study the histopathological features of leprosy in skin biopsies and classify based on microscopy, bacterial index to correlate with clinical presentations. MATERIAL AND METHODS:- A retrospective observational study was done at Department of Pathology of Universal College of Medical Sciences (UCMS) Bhairahawa for 2 years from 1st November 2015 to 31stOctober 2017 and total 68 cases were analysed. Cases in which histopathological diagnosis of leprosy was made or considered differential diagnosis were selected for study. Ridley and Jopling classification was used histologically to make diagnosis of leprosy. Copies of issued histopathology reports, that are preserved in the department routinely were used to obtain data pertaining to age, sex, clinical information and histopathological findings. RESULTS:- This study included 68 patients diagnosed histologically as leprosy. Histopathological examination of the skin biopsies of 68 patients revealed that, the maximum histopathological cases 28 (41.17%) are BT followed by 15 cases (22.05%) of IL (15) and 9 (13.23%) of TT. Complete parity between clinical diagnosis and histopathology was observed in 55.88 % and disparity was seen in 44.12%. CONCLUSION:- For proper classification of Leprosy, correlation of clinical and histopathological features along with bacterial index is more useful than considering any of the single parameter.

scholarly journals Spectrum of Malignant Skin Lesion in Patients attending Nepalgunj Medical College and Teaching Hospital

2017 ◽  
Vol 2 (2) ◽  
pp. 156-161
Author(s):  
Reena Rana ◽  
G P Ghimire ◽  
S Gupta ◽  
M Singh ◽  
KK Jha ◽  
...  
Keyword(s):  
Skin Lesion ◽  
Clinical Diagnosis ◽  
Teaching Hospital ◽  
Malignant Tumor ◽  
Histopathological Examination ◽  
Cross Sectional Study ◽  
Histopathological Diagnosis ◽  
Cross Sectional ◽  
Medical College ◽  
Histopathological Correlation

IntroductionClinical diagnosis of dermatological manifestation of neoplastic skin lesion can pose a diagnostic difficulty at times. Histopathological diagnosis is mandatory for accurate characterization of disease entity for proper and timely management of cases.ObjectiveThe aim of this study was to analyze malignant tumor of skin with respect to age, sex, clinical features and histopathological features and to evaluate the accuracy of clinical diagnosis with histopathological correlation.MethodologyThis is hospital based cross-sectional study conducted at Nepalgunj Medical College and Teaching Hospital, Kohalpur from February 2010 to January 2011. A total of 70 histopathological specimens of skin biopsies were studied and correlated with the clinical diagnosis. The data was entered into Microsoft  office excel and analyzed using statistical package for social sciences (SPSS 17.0).ResultsMalignant tumor of skin constituted 21.4% of total cases. In malignant tumor, most common sites were head and neck regions followed by lower limb with keratinocytic tumors being in the majority. Most of the specimens (65.7%) were obtained as excisional biopsies.  Seven cases diagnosed as benign lesions clinically, turned out to be malignant on histopathological examination. Out of 13 cases in which clinical diagnosis was of malignancy, only 8 turned out to be malignant, thus for malignant lesions, the clinical diagnosis had a sensitivity of 53.3%, specificity of 90.9% and a positive predictive value of 61.5%.ConclusionsSquamous cell carcinoma was the most common malignant tumor in this study and histopathological correlation significantly modifies the overall management in dermatological disorders where clinical diagnoses are equivocal.Birat Journal of Health SciencesVol.2/No.1/Issue 2/ Jan - April 2017, Page: 156-161

scholarly journals Laparoscopic pelvic adnexal surgery in Nobel Medical College

2021 ◽  
Vol 16 (1) ◽  
pp. 65-68
Author(s):  
Amar Nath Chaudhary ◽  
Gehanath Baral ◽  
Prajmi Shrestha ◽  
Rakina Bhanshakarya
Keyword(s):  
Cystic Teratoma ◽  
Mature Cystic Teratoma ◽  
Histopathological Diagnosis ◽  
Adnexal Masses ◽  
Medical College ◽  
Obstetrics And Gynaecology ◽  
Adnexal Surgery ◽  
The Common ◽  
One Year ◽  
Observational Descriptive Study

Aim: To share early experience of gynaecological laparoscopic surgeries for adnexal masses in Nobel Medical College and Teaching Hospital (NMCTH). Methods: This is a observational descriptive study in the Department of Obstetrics and Gynaecology of Nobel Medical College, Biratnagar for one year in 2019-2020. All the patients undergoing laparoscopic pelvic surgeries for adnexal masses were analysed for indication, type of procedure, complications and histopathological diagnosis. Results: A total of 123 laparoscopic surgeries were performed. Preoperative diagnosis in most of the cases was adnexal mass followed by adnexal evaluation for subfertility. The common surgical procedure was cystectomy followed by salpingo-oophorectomy in 80% of cases. The most common histopathological diagnosis was mature cystic teratoma (42; 34%) followed by endometriosis (29; 23.8%) and cystadenoma (25; 20.3%). Conclusions: Adnexal evaluation and surgical treatment were performed with laparoscopy. The common pathologies were mature cystic teratoma, endometriosis and ovarian cystadenomas.

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