scholarly journals Feto-placental Changes in Pregnancy Induced Hypertension

Author(s):  
Sonti Sulochana ◽  
Krishna Priya ◽  
. Sindhuja

Aims: To study if there is any difference in the foetus and placenta of pregnant women who are normotensive and those of of hypertensive patients of different severity. Study Design:  Prospective study. Place and Duration of Study: Department of pathology, Saveetha institute of medical and technical sciences, between June 2017- June 2018. Methodology: Pregnant women with hypertension attending obstetrics and gynecology department, Saveetha Medical College, Chennai was studied during the study period. The study was conducted in accordance with the guidelines approved by the institutional review board of our Institution. The study population was divided into two groups namely normotensive and hypertensive patients. The hypertensive groups patients were further divided into two groups of mild (BP ≥140/90 mm Hg with proteinuria) and severe (BP ≥ 160/100 mm Hg with proteinuria). The placental specimens after expulsion were collected in 10% neutral buffered formalin solution. Informed consent was obtained in all patients and clinical data were obtained from the case notes. In the histopathology laboratory biopsy was taken from the insertion point of umbilical cord for light microscopy. P-values less than 0.05 were considered statistically significant. Data was entered in MS excel sheet and analysed using SPSS software version. Results: The placental weight, birth weight of baby and APGAR score was decreased in PIH patients than normal pregnant women. Conclusion: The diagnosis and treatment of PIH is very important to prevent complications in mother and baby.

2019 ◽  
Vol 16 (2) ◽  
pp. 54-59 ◽  
Author(s):  
Taslima Begum ◽  
Khr Md Shahjahan Ali ◽  
Shafeya Khanam ◽  
Md Anwar Habib ◽  
Shipra Chaudhury ◽  
...  

Background: The clinical profiles and urinary albumin are very important for the prediction of preeclampsia among the pregnant women. Objective: The purpose of the present study was to assess the clinical and demographic profiles as well as the urinary albumin for the prediction of preeclampsia among the pregnant women. Methodology: This cohort study was conducted in the OPD of the Department of Obstetrics and Gynaecology at Rajshahi Medical College Hospital, Rajshahi, Bangladesh from January 2013 to December 2014 for a period of two (2) years. This study was carried on pregnant woman attending in outdoor department of Gynaecology, Rajshahi Medical College Hospital, Rajshahi, Bangladesh before 20th weeks of pregnancy who were healthy normotensive primigravidae with singleton pregnancy. The details demographic profiles, edema were collected from the study population. Urinary albumin was estimated before 20th weeks and after 28th weeks of pregnancy. Result: In the present study, 75 women were included; all were before 20th weeks of pregnancy without any complication or any risk factor for developing PE. Among the study group incidence of PE was 16%. The population are 24(32.0%) low, 31(41.3%) middle and 20(26.7%) high in socio economic conditions. Education level of study population was 45% completed primary education level, illiterate (27%) and secondary education (28%). Edema was absent in 1st visit, in 2nd visit 6(+), 6(++) present who developed PE, 18(+) present who did not develop PE. Edema was absent in 1st visit and (+) 6(50.0%) and (++) in 6(50.0%) present who developed PE in 2nd visit. Urine albumin in 1st visit nil in 6(50.0%), trace in 3(25.0%) and (+) in 3(25.0%) who developed PE. Conclusion: In conclusion housewife living in urban area in middle income socioeconomic condition are the most commonly presented with preeclampsia and urinary albumin is the most commonly detected in the pregnant women presented with preeclampsia Journal of Science Foundation 2018;16(2):54-59


2021 ◽  
Vol 4 (2) ◽  
pp. 162
Author(s):  
Elluru Pandu Rangaiah ◽  
Madhavi Latha Gangisetty ◽  
Sandhya K ◽  
Latha A ◽  
Meena Syed

Introduction: Hypertensive disorders complicate 5-10% in all pregnant and together form the deadly triad and hemorrhage and heart disease that contribute greatly to maternal morbidity or mortality. This study aims to identify retinal changes in pregnancy-induced hypertension and analyze the association between retinal changes and hypertension severity. Method: A total of 100 pregnant admitted with pregnancy-induced hypertension(PIH) were included. Patients with pre-existing hypertension, diabetes mellitus, and renal diseases were excluded from the study. The vision, anterior segment, and Fundus were examined. Result: Higher number of PIH were recorded in the 21-30 years age group. Fifty-four pregnant women suffered from mild preeclampsia, 40 pregnant women with severe preeclampsia, and six pregnant women with eclampsia with seizures. 41% of pregnant had normal fundus, and 24% of pregnant had hypertensive retinopathy. Whereas grade 2,3, and 4 retinopathy was observed in 22%, 6%, and 2% of pregnant women. Two percent of pregnants had macular edema, and 3% had central serous retinopathy. No association was observed between the fundus findings with age/gravida. Whereas a significant positive correlation was observed between the fundus findings and hypertension severity (P < 0.001). Conclusion: Overall, 54% of pregnants were recorded with hypertensive retinopathy. A positive correlation was observed between fundus changes with the hypertension severity. This study reports the importance of routine fundus examination in pregnant with hypertension. Retinal change during pregnancy is an important indicator to decide the pregnancy termination or any other opt.


2020 ◽  
Vol 58 (232) ◽  
Author(s):  
Pratibha Manandhar ◽  
Naresh Manandhar ◽  
Sunil Kumar Joshi

Introduction: Almost a billion people in the world are affected by Vitamin D deficiency. During pregnancy, the deficiency of Vitamin D can manifest as gestational diabetes, pre-eclampsia, preterm birth, or miscarriage in the early stages of pregnancy. The objective of this study was to assess the knowledge, attitude, and practice, and importance of Vitamin D among pregnant women via a focus group. Methods: A qualitative study was carried out at Changu Narayan Municipality, Duwakot ward no. two, Bhaktapur district from November to December 2019 after approval from the Institutional Review Committee of Kathmandu Medical College (Ref. 181020192). Participants were selected via the Female Community Health Volunteer’s pregnant women list by purposive sampling method. Focus group discussion was conducted among pregnant women. The interview questions were open-ended and the data were analyzed using thematic analysis. Results: Study participants showed limited knowledge on vitamin D. Few participants had information regarding sun exposure for vitamin D. But many participants had negative attitudes towards sun exposure and lack of knowledge on sun exposure requirements. The participants have a huge knowledge gap between Vitamin D and its importance in pregnancy. Conclusions: Increasing awareness of the importance of Vitamin D among pregnant women is required.


2017 ◽  
Vol 7 (1) ◽  
pp. 6-9
Author(s):  
Aftabun Nahar ◽  
Afroza Ghani ◽  
Serajoom Munira ◽  
Ashia Khatun ◽  
Rifat Sultana ◽  
...  

Background: Use of misoprostol in term pregnancy can give some maternal adverse events.Objective: The purpose of the present study was to see the maternal outcome among the term pregnant women.Methodology: This descriptive, prospective cohort study was carried out in the Department of Obstetrics and Gynaecology at Sir Salimullah Medical College and Mitford Hospital during the period from September 2005 to February 2006. Primi or second gravida patients with the gestational age between 37 weeks to 42 weeks in singleton pregnancy with cephalic presentation and not in labour who came for delivery purposes during the study period at any age were selected as study population. After proper selection of the cases, induction of labour (IOL) was done by applying tablet Misoprostol 5omcg in the posterior vaginal fomix. Purpose of induction of labour was successful when vaginal delivery occurred Without any untoward side effects and Without any surgical interference.Result: A total number of 60 pregnant women were recruited in this study of which 60% patients were within 23-30 years of age. Out of 43 cases of vaginal delivery 22 cases needed 1 dose of Misoprostol 21 cases needed more than 1 dose. 60% of study population who were primigravide had vaginal delivery in 67% cases and caesarean section in 33% cases and among 40% 2nd gravida cases vaginal delivery was 79% and caesarean delivery was 21%.Conclusion: In the conclusion, the use of Misoprostol results in a shorter induction to delivery time, a reduction in the rate of caesarean delivery and also did not appear to produce miserable adverse effects on the method of delivery or the foetus.J Shaheed Suhrawardy Med Coll, 2015; 7(1):6-9


2018 ◽  
Vol 5 (1) ◽  
pp. 29-32
Author(s):  
Dewan Shahida Banu ◽  
Rifat Sultana ◽  
Mahmuda Khatun ◽  
Rowshan Hosne Jahan ◽  
Faiza Chowdhury ◽  
...  

Background: Foetal outcome is a great concern among the primigravida women presented with fetal head engagement.Objectives: The purpose of the present study was to see foetal outcome among the women presented with fetal head engagement.Methodology: This descriptive cohort study was carried out in the Department of Gynecology and Obstetrics at Sir Salimullah Medical College and Mitford Hospital, Dhaka from June 2006 to December 2006 for a period of sic (6) months. Primaigravida women with 38 or more weeks of pregnancy having single foetus with cephalic presentation were selected as study population. Foetal outcome was measured in terms of APGAR score.Result: A total number of 1440 pregnant women were recruited for this study. In this study the APGAR score of all the babies were good. APGAR score were low in l2 cases and returned to normal alter resuscitation. Out of 262 engaged cases 7 to 10 APGAR score was found in 261(99.6%) cases. In 1178 unengaged cases 7 to 10 APGAR score was found in 1167(99.1%) cases. APGAR score 4 to 6 was found in 1 case and 11 cases in engaged and unengaged group. However, 0 to 3 APGAR score was not reported in engaged and unengaged group. There was no statistical significant between the engaged and unengaged group considering the APGAR score of 7 to 10 and 4 to 6 (p=0.374).Conclusion: In conclusion fetal outcome is not significantly different between the engaged and unengaged pregnant women during considering the APGAR score.Journal of Current and Advance Medical Research 2018;5(1):29-32


2021 ◽  
Vol 2 (1) ◽  
pp. 25-34
Author(s):  
DM Chia ◽  
IT Annongu ◽  
BT Utoo ◽  
M Hameed ◽  
A Abdullahi ◽  
...  

Fetal gender disclosure, a non-medical prenatal ultrasonography indication, although largely ethically unjustifiable, continues to grow and thrive in demand due to its request by pregnant women. The study aims at establishing the proportion of women who want to know fetal gender during prenatal ultrasound. This was twelve months` prospective study of all pregnant women, 16weeks and above who presented at our facility for antenatal ultrasound in Makurdi from 7th May 2019 to 6th May 2020. A structured questionnaire was used to obtain information on factors influencing their willingness to know the gender of their unborn children. The information collated was entered into statistical package for social science (SPSS) version 23.0 for analysis. P-values=0.005 was considered significant for the study population. Two hundred and fifty (250) pregnant women were recruited for the study. Majority of the women 233(93.2%) showed marked interest in knowing the gender of the fetus, while 17(6.8%) did not. The main reason for wanting to know the sex of the fetus was for easier choice of clothing and naming; whereas the main reason for not wanting sex disclosure was because any child is good. There was no statistically significant correlation between gender preferences and the other variables such as age, educational attainment, tribe and previous miscarriages (P=0.136, 0.485, 0.275 and 0.942 respectively). Majority of the women 233(93.2%) want fetal gender disclosure due to ease of choice of clothing and naming. The deliberate policy of non-disclosure on account of non-medical indication during prenatal ultrasonography is untenable in our environment.


Author(s):  
Ruqayya Chandio ◽  
Jawaid Hussain Lighari Baloch ◽  
Nusrat Fozia Pathan ◽  
Attia Ayoob ◽  
Noor Ali Samoon ◽  
...  

Objectives: To assess of the pregnancy induced hypertension and gravida in teen age girls at People Medical College Hospital Nawabshah Pakistan. Methodology: This cross-sectional study was carried out on 200 pregnant women from Gynecology & Obstetrics Department of Unit-1 and 2 People Medical College Hospital Nawabshah from January 2018 to December 2018. The sampling technique was convenience sampling. The frequency and association between the hypertension and Gravida were observed. Blood Pressure was taken by sphygmomanometer of mercury type B.P apparatus from 200 pregnant women and interviewed all the study subjects. A well designed and structured questionnaire (consist of age, gravida and hypertension related questions) was used for data collection and analyzed statistically. The data was analyzed statistically by SPSS Version 20.0. Results: The mean age of married teenage girls was 16.6 Years with SD ± 2.3 Years. The study results show that 23.5% of Teenage mothers were suffering from Pregnancy Induced Hypertension. 83% women participants were in the age group of 17 to 19 years. Majority 80.3% of marriages were in the age of 13 to16 years. 76% of women were in 1st and 2nd Gravida. Conclusion: One fourth of Teenage married girls are suffering from Pregnancy Induced Hypertension. The maternal age of 17-19 years has been found most common age group for pregnancy induced hypertension, more common in 1st and 2nd Gravida.


Author(s):  
Suhail Iqbal ◽  
Aditi Sharma

Background: One of the most common and potential life-threatening complications of pregnancy is pregnancy induced hypertension. Though platelet count during pregnancy is within the normal non-pregnant reference values, there is a tendency for the platelet count to fall in late pregnancy. The frequency and intensity of maternal thrombocytopenia varies and is dependent on the intensity and severity of PIH.Methods: This prospective study was conducted in the Department of obstetrics and gynecology in Jhalawar medical college from January 2018 to April 2018.Total 120 pregnant women during third trimester (32-40 weeks) aged 18 to 35 years were selected. Among them 63 were preeclamptic patients and 63 were healthy normotensive control. Subjects and healthy pregnant women (control) visiting the Obstetrics and Gynecology department of Jhalawar Medical College were registered in the study and followed during their pregnancy. Both, subjects and control participants were subject to platelet count manually and MPV was determined by an automated analyser (sysmex XN-1000™) performed using standard methods on.Results: The mean platelet count of the subject group (131.4937±62.05999 lakh/mm3) was significantly lower than that of the control group (324.9683±230.78764 lakh/mm3). This shows that there is thrombocytopenia found in patients with P.I.H in their third trimester. On the other hand, the p value of “mean platelet volume” in patients with preeclampsia was (p<0.0001) which shows that there is no significant difference in MPV of cases (7.1438±2.62 femtolitre) and control (7.8976±3.08 femtolitre) (p>0.142), regular monitoring of platelet counts in women with Pregnancy Induced Hypertension must be subject of the management protocols.Conclusions: In present study we observed that the number of thrombocytopenic subjects was higher in cases of preeclampsia as compared to the control group. These extrapolations indicate that there might be some important mechanism which interferes with platelets life span thus reducing the number of functional platelets in circulation. The platelet count has an association at prediction of increasing grade of PIH. There is an inverse relationship between the severity of PIH and platelet count. The depleted platelet counts are concluded to be consistently associated with clinical groups of severe preeclampsia and the risk of consumptive coagulopathy.


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