Fluctuating Number of Energy Levels in Mixed-Type Lemon Billiards

In this paper, the fluctuation properties of the number of energy levels (mode fluctuation) are studied in the mixed-type lemon billiards at high lying energies. The boundary of the lemon billiards is defined by the intersection of two circles of equal unit radius with the distance 2B between the centers, as introduced by Heller and Tomsovic. In this paper, the case of two billiards, defined by B=0.1953,0.083, is studied. It is shown that the fluctuation of the number of energy levels follows the Gaussian distribution quite accurately, even though the relative fraction of the chaotic part of the phase space is only 0.28 and 0.16, respectively. The theoretical description of spectral fluctuations in the Berry–Robnik picture is discussed. Also, the (golden mean) integrable rectangular billiard is studied and an almost Gaussian distribution is obtained, in contrast to theory expectations. However, the variance as a function of energy, E, behaves as E, in agreement with the theoretical prediction by Steiner.

Aqueous-phase reactive species formed by fine particulate matter from remote forests and polluted urban air

In the aqueous phase, fine particulate matter can form reactive species (RS) that influence the aging, properties, and health effects of atmospheric aerosols. In this study, we explore the RS yields of aerosol samples from a remote forest (Hyytiälä, Finland) and polluted urban locations (Mainz, Germany; Beijing, China), and we relate the RS yields to different chemical constituents and reaction mechanisms. Ultra-high-resolution mass spectrometry was used to characterize organic aerosol composition, electron paramagnetic resonance (EPR) spectroscopy with a spin-trapping technique was applied to determine the concentrations of ⚫OH, O2⚫-, and carbon- or oxygen-centered organic radicals, and a fluorometric assay was used to quantify H2O2. The aqueous H2O2-forming potential per mass unit of ambient PM2.5 (particle diameter < 2.5 µm) was roughly the same for all investigated samples, whereas the mass-specific yields of radicals were lower for sampling sites with higher concentrations of PM2.5. The abundances of water-soluble transition metals and aromatics in ambient PM2.5 were positively correlated with the relative fraction of ⚫OH and negatively correlated with the relative fraction of carbon-centered radicals. In contrast, highly oxygenated organic molecules (HOM) were positively correlated with the relative fraction of carbon-centered radicals and negatively correlated with the relative fraction of ⚫OH. Moreover, we found that the relative fractions of different types of radicals formed by ambient PM2.5 were comparable to surrogate mixtures comprising transition metal ions, organic hydroperoxide, H2O2, and humic or fulvic acids. The interplay of transition metal ions (e.g., iron and copper ions), highly oxidized organic molecules (e.g., hydroperoxides), and complexing or scavenging agents (e.g., humic or fulvic acids) leads to nonlinear concentration dependencies in aqueous-phase RS production. A strong dependence on chemical composition was also observed for the aqueous-phase radical yields of laboratory-generated secondary organic aerosols (SOA) from precursor mixtures of naphthalene and β-pinene. Our findings show how the composition of PM2.5 can influence the amount and nature of aqueous-phase RS, which may explain differences in the chemical reactivity and health effects of particulate matter in clean and polluted air.

A potential role for somatostatin signaling in regulating retinal neurogenesis

Neuropeptides have been reported to regulate progenitor proliferation and neurogenesis in the central nervous system. However, these studies have typically been conducted using pharmacological agents in ex vivo preparations, and in vivo evidence for their developmental function is generally lacking. Recent scRNA-Seq studies have identified multiple neuropeptides and their receptors as being selectively expressed in neurogenic progenitors of the embryonic mouse and human retina. This includes Sstr2, whose ligand somatostatin is transiently expressed by immature retinal ganglion cells. By analyzing retinal explants treated with selective ligands that target these receptors, we found that Sstr2-dependent somatostatin signaling induces a modest, dose-dependent inhibition of photoreceptor generation, while correspondingly increasing the relative fraction of primary progenitor cells. These effects were confirmed by scRNA-Seq analysis of retinal explants but abolished in Sstr2-deficient retinas. Although no changes in the relative fraction of primary progenitors or photoreceptor precursors were observed in Sstr2-deficient retinas in vivo, scRNA-Seq analysis demonstrated accelerated differentiation of neurogenic progenitors. We conclude that, while Sstr2 signaling may act to negatively regulate retinal neurogenesis in combination with other retinal ganglion cell-derived secreted factors such as Shh, it is dispensable for normal retinal development.

Regulation of retinal neurogenesis by somatostatin signaling

Neuropeptides have been reported to regulate progenitor proliferation and neurogenesis in the central nervous system. However, these studies have typically been conducted using pharmacological agents in ex vivo preparations, and in vivo evidence for their developmental function is generally lacking. Recent scRNA-Seq studies have identified multiple neuropeptides and their receptors as being selectively expressed in neurogenic progenitors of the embryonic mouse and human retina. This includes Sstr2, whose ligand somatostatin is transiently expressed by immature retinal ganglion cells. By analyzing retinal explants treated with selective ligands that target these receptors, we found that Sstr2-dependent somatostatin signaling induces a dose-dependent inhibition of photoreceptor generation while increasing the relative fraction of primary progenitor cells. These effects were confirmed by scRNA-Seq analysis of retinal explants and abolished in Sstr2-deficient retinas. Although no changes in the relative fraction of primary progenitors or photoreceptor precursors were observed in Sstr2-deficient retinas in vivo, scRNA-Seq analysis demonstrated accelerated differentiation of neurogenic progenitors. We conclude that Sstr2 signaling may act to negatively regulate retinal neurogenesis in combination with other retinal ganglion cell-derived secreted factors such as Shh, although in vivo Sstr2 is dispensable for normal retinal development.

Star formation and AGN activities in selected nearby HII galaxies in the LeMMINGS survey

We investigate the relative fraction of the emission generated by star formation and nuclear activities in 6 nearby HII galaxies selected from the first high resolution radio data release of LeMMINGS, the Legacy e-MERLIN Multi-band Imaging of Nearby Galaxies Survey. These galaxies are supposed to be powered solely by star formation according to the BPT diagram but exhibit jetted morphologies on parsec scales indicating the presence of a low luminosity AGN. We further carried out a multi-wavelength SED fiiting and analysis using the CIGALE code, estimating stellar masses and star formation rates.

Rapid and Effective Isolation of Dissolved Organic Matter Using Solid-Phase Extraction Cartridges Packed with Amberlite XAD 8/4 Resins

Using the conventional XAD 8/4 method with general columns to isolate dissolved organic matter (DOM) is extremely time-consuming and labor-intensive. This study presents a rapid and effective method using solid-phase extraction (SPE) cartridges packed with XAD 8/4 resins for isolating various DOMs. The relative fraction (percentage hydrophobic, transphilic, and hydrophilic) of the various DOMs processed by both methods showed similar values. Moreover, changes in the molecular weight distribution of effluent from XAD 8/4 resins processed by both methods showed the same ultraviolet (UV) and fluorescence absorbance pattern s. The biopolymer compositions of eluates from XAD 8/4 resins also showed no significant difference between the two methods. However, higher carbon recovery of the isolation method using SPE cartridges was found (with columns: 88.9%; with SPE: 95.9%). In addition, the proposed method using SPE cartridges packed with XAD 8/4 resins is much faster than that using general columns (with columns: 1468 min; with SPE: 485 min). The proposed isolation method is highly efficient and accurate; it is an excellent candidate method for isolating various DOMs.

Weighing the two stellar components of the Galactic bulge

Context.Recent spectroscopic surveys of the Galactic bulge have unambiguously shown that the bulge contains two main components, which are best separated by their iron content, but also differ in spatial distribution, kinematics, and abundance ratios. The so-called metal poor component peaks at [Fe/H] ∼ −0.4, while the metal rich component peaks at [Fe/H] ∼ +0.3. The total metallicity distribution function is therefore bimodal with a dip at [Fe/H] ∼ 0. The relative fraction of the two components changes significantly across the bulge area. Aims. We provide, for the first time, the fractional contribution of the metal poor and metal rich stars to the stellar mass budget of the Galactic bulge and its variation across the bulge area. Methods. This result follows from the combination of the stellar mass profile obtained empirically, by our group, from VISTA Variables in the Vía Láctea data, with the relative fraction of metal poor and metal rich stars, across the bulge area, derived from the GIRAFFE Inner Bulge spectroscopic Survey. Results. We find that metal poor stars make up 48% of the total stellar mass of the bulge, within the region |l| < 10, |b| < 9.5 and that the remaining 52% are made up of metal rich stars. The latter dominate the mass budget at intermediate latitudes |b| ∼ 4, but become marginal in the outer bulge (|b| > 8). The metal poor component is more axisymmetric than the metal rich component, and it is at least comparable and possibly slightly dominant in the inner few degrees. As a result, the metal poor component, which does not follow the main bar, is not marginal in terms of the total mass budget as previously thought, and this new observational evidence must be included in bulge models. While the trend of the total radial velocity dispersion follows the total stellar mass, when we examine the velocity dispersion of each component individually, we find that metal poor stars have higher velocity dispersion where they make up a smaller fraction of the stellar mass, and vice versa. This is due to the kinematical and spatial distribution of the two metallicity components being significantly different, as already discussed in the literature.

Active apolar doping determines routes to colloidal clusters and gels

Collections of interacting active particles, self-propelling or not, have shown remarkable phenomena including the emergence of dynamic patterns across different length scales, from animal groups to vibrated grains, microtubules, bacteria, and chemical- or field-driven colloids. Burgeoning experimental and simulation activities are now exploring the possibility of realizing solid and stable structures from passive elements that are assembled by a few active dopants. Here we show that such an elusive task may be accomplished by using a small amount of apolar dopants, namely synthetic active but not self-propelling units. We use blue light to rapidly assemble 2D colloidal clusters and gels via nonequilibrium diffusiophoresis, where microscopic hematite dockers form long-living interstitial bonds that strongly glue passive silica microspheres. By varying the relative fraction of doping, we uncover a rich phase diagram including ordered and disordered clusters, space-filling gels, and bicontinuous structures formed by filamentary dockers percolating through a solid network of silica spheres. We characterize the slow relaxation and dynamic arrest of the different phases via correlation and scattering functions. Our findings provide a pathway toward the rapid engineering of mesoscopic gels and clusters via active colloidal doping.

Morphological substantiation of the use of laser and led irradiation in emergent treatment of ulcer complications

The structural basis of ulcer perforation and bleeding was determined, based on morphological evaluation of gastroduodenal ulcers. The effects of low-intensive laser irradiation LILI and LED irradiation on pathomorphosis of ulcers were studied. It was found that the local phototherapy with LILI and LED increases the relative fraction volume — RFV of fibroblasts and connective tissue fibers, reduces RFV of cell-free zones, which contributes to “strengthening” of the ulcer walls and prevents their perforation. These same photo-infllead to an increase of RFV of blood vessels, indicating inappropriateness of their use for local phototherapy in bleeding ulcers.