The holy grail of pyrene-based surface ligands on the sensitivity of graphene-based field effect transistors

Graphene has witnessed intensive research interest due to its remarkabe charge mobility and the efforts in the use of graphene-based field effect transistors (GFET) for sensing of biological biomarkers is...

Why don’t we look to the west?

Paleontological data indicate that the beginning of Java Island’s human habitation took place at the Plio-Pleistocene boundary, around 2.4 Ma, along with uplift process and glacial-interglacial cycles. However, the oldest Homo erectus fossil was mainly found in the eastern part of Java Island where age-dating indicates that they were from ca. 1.5 Ma, especially along the riverbanks of Bengawan Solo and Brantas, such as Perning, Sangiran, Kedungbrubus, Ngandong, Ngawi, Trinil, and Sambungmacan.Recently, Pleistocene sites were discovered from the western part of Java, e.g., Rancah (Ciamis), Semedo (Tegal), and Bumiayu (Brebes) with their archeological, paleontological, and paleoanthropological potentials. This work will present the significance of the potential, especially paleoanthropological data from the new sites, and their implications to the Quaternary prehistory research strategies determination in the future.We present new geological, archeological, paleontological, and paleoanthropological evidence from those mentioned sites. The result shows that the distribution of Homo erectus were extended to the western part of Java, between 1.8-1.7 Ma, older than the oldest previous finding of Homo erectus from Perning and Sangiran. This finding suggests a new window of the human arrival on this island. So, why don’t we look to the west? Intensive research in the future should be addressed to the western part of Java Island.

Membrane-Mediated Interactions Between Protein Inclusions

Integral or peripheral membrane proteins, or protein oligomers often get close to each other on cell membranes and carry out biological tasks in a collective manner. In addition to electrostatic and van der Waals interactions, those proteins also experience membrane-mediated interactions, which may be necessary for their functionality. The membrane-mediated interactions originate from perturbation of lipid membranes by the presence of protein inclusions, and have been the subject of intensive research in membrane biophysics. Here we review both theoretical and numerical studies of such interactions for membrane proteins and for nanoparticles bound to lipid membranes.

Extending the Unmixing methods to Multispectral Images

In the past few decades, there has been intensive research concerning the Unmixing of hyperspectral images. Some methods such as NMF, VCA, and N-FINDR have become standards since they show robustness in dealing with the unmixing of hyperspectral images. However, the research concerning the unmixing of multispectral images is relatively scarce. Thus, we extend some unmixing methods to the multispectral images. In this paper, we have created two simulated multispectral datasets from two hyperspectral datasets whose ground truths are given. Then we apply the unmixing methods (VCA, NMF, N-FINDR) to these two datasets. By comparing and analyzing the results, we have been able to demonstrate some interesting result for the utilization of VCA, NMF, and N-FINDR with multispectral datasets. Besides, this also demonstrates the possibilities in extending these unmixing methods to the field of multispectral imaging.

Ethnomycological research in the field of wild mushrooms and medicinal plants

During the recent years, there is an increased interest in the problems of wild mushrooms and medicinal plants in all over the world. An intensive research is currently performed in order to further clarify the peculiarities of numerous edible, toxic and cultivated wild mushrooms and medicinal plants. Both traditional and contemporary knowledge of the population is assessed by means of a variety of ethnomycological and ethnobotanical methods. The manners of usage by the population of wild edible mushroom and medicinal plants are intensively studied in many countries, too. In the present review article, the results from some recent investigations by Bulgarian and foreign authors devoted to the knowledge and use of some popular wild mushrooms and medicinal plants are summarized. The necessity for the intensification of the collaborative ethnomycological and ethnobotanical research in Europe is outlined.

The New Phi Function and some of it's Applications

In Mathematics, we see a large number of functions, each having its own properties. Some of these are very interesting and contribute greatly to the intensive research in the field of Mathematics. This paper deals with one such function (which we have termed as the phi function) which emerges from a chain of inequalities, established from the basic concepts of differential calculus. This paper establishes several inequalities which relate to functions and their integrals. Another important expression (from the point of view of notations) links a class of divergent infinite series to the phi function. Finally, we will dive into a brief overview of the phi-form of plane trigonometric functions and derive the trigonometric identity sin2(θ) + cos2(θ) = 1, thus marking their importance. Throughout the paper, we will be analyzing functions in R+ such that the functions are always greater than 0. We will also consider that the functions are continuous and differentiable in the intervals under consideration.

Prurigo nodularis, prurigo chronica, new therapeutic options

Prurigo nodularis (PN) is a skin disease that develops on chronically itchy skin. There are various causes behind the chronic itch. Due to intensive research in recent years different mechanisms that can participate in the development of chronic pruritus have been discovered, opening up new therapeutic targets for treatment. Here we review the various mechanisms behind chronic pruritus and discuss the novel therapies for PN.

NOVEL SOFTWARE IN MATLAB DESIGNED FOR UWB SENSOR-BASED LOCALIZATION OF PEOPLE IN 2D AND 3D SPACE

Detection, localization, and tracking of people in 2D or 3D space using Ultra-wideband (UWB) short-range sensors is a subject of worldwide intensive research. In this paper, we describe a proposal for a novel software called UWB-PerLoc-2D3D. This software has been created in a MATLAB programming environment and designed to process UWB radar signals for the purpose of movement monitoring of human targets in 2D and 3D space. We present an evaluation of the proposed software properties as well as examples of its utilization in practice.

Use of Augmented Reality in Assembly Process

Intensive research is currently underway into the concept of intelligent assembly, which integrates production processes, people, hardware and information using both real and virtual methods to achieve significant improvements in productivity, delivery time and combined market turnover. This paper describes the use of augmented reality in the assembly process at the workplace, which by integrating hardware and software equipment will enable an innovative assembly workplace for a manufacturing and development company. The assembly workplace will speed up and facilitate assembly and prevent the creation of failures and restrictions during assembly.

Development of the Car Seat through a Wider Range of Active Elements Implementation

Car seats represent a constructive - functional system including a variety of elements, assembled on a specific frame, among those the main components are the seat pan, the seat backrest, and the seat headrest. In order to improve the comfort of the driver and passengers, as well vehicle general safety, the car seats are under of intensive research and implementation of advanced developments.Thus, through of variety of sensors integrated into the seat, some important parameters are analysed for keeping the drivers alert and comfortable while driving semi-autonomous or autonomous cars. For adjustment of the seat linear and angular positions, a special system has been implemented, comprising electric, electronic, and pneumatic elements. Also, seat micro-adjustments are possible through the action of specific actuators. The car seat design and manufacture take into consideration a diverse array of data, based on a large range of parameters to face the diversity of drivers requirements. The present paper is advancing a conceptual development of car complex seat, integrating a number of active elements, with multiple possible adjustments. The new seat model is designed to satisfy a larger diversity of people both in terms of comfort and safety.