CREATING 3D-DATABASE FROM IMAGES AS TOOL FOR RECORDING BUILDINGS, IN CITIES WITH NATURAL DISASTER HAZARD

Preparing for natural disasters is vital for mitigating harm and loss of important cultural sites. In Cuba, this rigorous planning informed by years of experience has focused on the recuperation phase after a disaster or storm. Governmental agencies plan rehabilitation and reconstruction projects in the short, medium, and long term. Accurate models are essential for planning these recovery projects. Photogrammetry represents a novel way to create these models at a potentially city-wide scale. Images taken with conventional cameras are used for object measurement to create digital 3D models of buildings, which will be stored in an architectural database. Important cultural and historic sites were used as initial case studies for the creation of models through photogrammetry. These catalogs will facilitate the maintenance and assessment of these important sites and help to plan future reconstruction plans after a natural disaster. Photogrammetric corrections cause minimal graphic distortion to provide accurate metrics of geometric and decorative information. Examples of these techniques in other Latin American cities will also be discussed.

HBIM MODELLING FOR AN HISTORICAL URBAN CENTRE

The research in the geospatial data structuring and formats interoperability direction is the crucial task for creating a 3D Geodatabase at the urban scale. Both geometric and semantic data structuring should be considered, mainly regarding the interoperability of objects and formats generated outside the geographical space. Current reflections on 3D database generation, based on geospatial data, are mostly related to visualisation issues and context-related application. The purposes and scale of representation according to LoDs require some reflections, particularly for the transmission of semantic information.This contribution adopts and develops the integration of some tools to derive object-oriented modelling in the HBIM environment, both at the urban and architectural scale, from point clouds obtained by UAV (Unmanned Aerial Vehicle) photogrammetry.One of the paper’s objectives is retracing the analysis phases of the point clouds acquired by UAV photogrammetry technique and their suitability for multiscale modelling. Starting from UAV clouds, through the optimisation and segmentation, the proposed workflow tries to trigger the modelling of the objects according to the LODs, comparing the one coming from CityGML and the one in use in the BIM community. The experimentation proposed is focused on the case study of the city of Norcia, which like many other historic centres spread over the territory of central Italy, was deeply damaged by the 2016-17 earthquake.

PSC-db: A Structured and Searchable 3D-Database for Plant Secondary Compounds

Plants synthesize a large number of natural products, many of which are bioactive and have practical values as well as commercial potential. To explore this vast structural diversity, we present PSC-db, a unique plant metabolite database aimed to categorize the diverse phytochemical space by providing 3D-structural information along with physicochemical and pharmaceutical properties of the most relevant natural products. PSC-db may be utilized, for example, in qualitative estimation of biological activities (Quantitative Structure-Activity Relationship, QSAR) or massive docking campaigns to identify new bioactive compounds, as well as potential binding sites in target proteins. PSC-db has been implemented using the open-source PostgreSQL database platform where all compounds with their complementary and calculated information (classification, redundant names, unique IDs, physicochemical properties, etc.) were hierarchically organized. The source organism for each compound, as well as its biological activities against protein targets, cell lines and different organism were also included. PSC-db is freely available for public use and is hosted at the Universidad de Talca.

Pan-Cancer Analysis and Drug Formulation for GPR139 and GPR142

GPR (G protein receptor) 139 and 142 are novel foundling GPCRs (G protein-coupled receptors) in the class “A” of the GPCRs family and are suitable targets for various biological conditions. To engage these targets, validated pharmacophores and 3D QSAR (Quantitative structure-activity relationship) models are widely used because of their direct fingerprinting capability of the target and an overall accuracy. The current work initially analyzes GPR139 and GPR142 for its genomic alteration via tumor samples. Next to that, the pharmacophore is developed to scan the 3D database for such compounds that can lead to potential agonists. As a result, several compounds have been considered, showing satisfactory performance and a strong association with the target. Additionally, it is gripping to know that the obtained compounds were observed to be responsible for triggering pan-cancer. This suggests the possible role of novel GPR139 and GPR142 as the substances for initiating a physiological response to handle the condition incurred as a result of cancer.

Use of Modern Technologies for the Conservation of Historical Heritage in Water Management

Historical monuments represent a cultural heritage that humanity has a duty to preserve and conserve. Lately all over the world, scanning these heritage objectives has become a priority, in order to preserve in the smallest details the used architecture. The work aims to complete the cultural heritage for Sânmihaiu Român hydro technical development built between 1912 and 1915, located on the Bega River in Western Romania, through modern mobile scanning technology, Leica Pegasus Backpack, necessary for the creation of a three-dimensional (3D) documentation, for the completion of the cultural heritage, and for the creation of a 3D database. The purpose of the scientific paper is restoring Sanmihaiu Roman Hidro technical Node, subject to degradation, in order to achieve the project “The navigable Bega”, waterway connection to Serbia. Collecting method of LiDAR data is Fused Slam, the acquisition of RINNEX data being made by placing a Leica GS08 Master Station. Visualization of quality graphics has been performed in Quality Control (QC) Tools. The scanning accuracy is between 2 and 3 cm and the 3D data processing was performed with the Cyclone Model version program, with SmartPick Point and Virtual Surveyor functions. The obtained point clouds will be of a great help in order to follow in time the construction which can be used whenever it will be needed by the designers and specialists in the field of hydrotechnics.

Variability of functional knee phenotypes in osteoarthritic knees shows that a more personalized approach in TKA is needed

Aims and Objectives: Recently, the functional knee phenotype concept was introduced as a new system to classify the coronal alignment of the lower limb. Until now, this concept has only been applied to non-osteoarthritic knees. The purpose of this study was therefore to phenotype osteoarthritic knees according to this concept and investigate the distribution of these phenotypes. Materials and Methods: Preoperative CT scans of osteoarthritic knees scheduled for TKA collected between January 2017 and December 2019 in the KneePLAN 3D database (Symbios Orthopédie S.A.) were reviewed for patients meeting the following inclusion criteria: age>50 and <90, no signs of previous fractures, osteotomies and rheumatoid arthritis. A total of 2764 patients (1438 right and 1326 left lower limbs, Male:female ratio 1096 :1668) with a mean age ± standard deviation of 70±8.5years (range 50-90 years) were included. The following coronal alignment parameters were measured using a validated software (KneePLAN 3D, Symbios Orthopédie S.A): hip-knee-ankle angle (HKA), femoral mechanical angle (FMA), and tibial mechanical angle (TMA). Based on these measurements each leg was phenotyped according to the functional knee phenotype concept and the distribution of these phenotypes assessed. A phenotype thereby consists of a phenotype specific mean value (HKA, FMA or TMA value) and covers a range of ± 1.5° from this mean (e.g. 180°± 1.5). The phenotype specific mean values represent 3° increments of the angle starting from the rounded overall mean value of the angle. Results: There were 162 different functional knee phenotypes (122 male, 138 female and 97 mutual). The most common functional knee phenotype in males was VARHKA6°VARFMA3°NEUTMA0° accounting for 8% of all males. The most common functional knee phenotype in females was VARHKA3°NEUFMA0°NEUTMA0° accounting for 9% of the population. The ten most common functional phenotypes account for 50% and 42.8% of all females and males, respectively. Overall, 134 phenotypes accounted each for less than 1% of the total population (all 134 together for 26.4%). Conclusion: The broad variability of functional knee phenotypes in osteoarthritic knees shows that a more personalized TKA realignment strategy is needed. The challenge will be to identify the optimal alignment strategy for each functional knee phenotype.

3D GEOSPATIAL DATABASE SCHEMA FOR ISTANBUL 3D CITY MODEL

This paper describes the development of 3D database for Istanbul 3D city models. The schema is based on object-relational technology and also called spatially-enhanced relational database management system (SRDBMS). The 3D city models were generated based on LiDAR points cloud with other several typical GIS datasets like terrain, orthophoto, Point of Interests (POIs), and other attribute data. The database is based on PostGIS schema and CityGML schema (3DCityDB). Two major datasets, namely, terrain data (with several formats), and 3D city models were populated in the database. Terrain and attributes data retrieval are based on Web Feature Service (WFS) whereas 3D models were visualized via 3D Tiles format in Cesium platform. Two issues were also highlighted in the paper with respect to 3D attributes linkages and 3D complex objects.

3D Modeling of Patrimonium Objectives Using Laser Technology

This paper aims to present the advantages of using the terrestrial laser scanning technology (TLS) as a method of creating a 3D database and 3D documentation. This state-of-the-art technology is an innovation that has the advantage of acquiring a large amount of data in a short time. This technology together with UAV equipment has the advantage of obtaining a digital terrain model. The creation of 3D patrimony models, archaeological objects and sites in their current state requires specialized equipment, knowledge, and have a powerful methodology capable of digitally capturing and shaping geometric details and fine layout of these sites. Digital recording, documentation and preservation are required because our patrimony (natural, cultural or mixed) suffers from various anthropogenic and/or natural actions (natural disasters, climate change and forgetfulness of human neglect).

THE VIRTUAL BATCAVE: A PROJECT FOR THE SAFEGUARD OF A UNESCO WHL FRAGILE ECOSYSTEM

<p><strong>Abstract.</strong> This abstract illustrates an interdisciplinary research project which focuses on the study, conservation and enhancement, through 3D digitization and virtual fruition, of an asset of great naturalistic, historical and ethnoanthropological value: Grotta dei Pipistrelli of Pantalica Nature Reserve (Sortino, SR). The cave (located in the Calcinara necropolis) is characterized by a great beauty as well as by a high cultural relevance and a remarkable scientific importance. In 2005, it awarded the UNESCO World Heritage title for its high historic, archaeological and speleological profile. Despite the site is being studied by specialists in chiropterofauna, nowadays there is not a comprehensive and reliable documentation of the plano-altimetric morphology of the cave, able to constitute a 3D database of essential information (e.g. morphological, geological, textural and wildlife information) for current and future studies, and to preserve the memory of this fragile ecosystem. The process of 3D digitization aims to create a model of the cave that allows us to enjoy this place, to explore it and to closely understand it in order to limit the anthropic pressure caused by visitors on the real site. Consequently, it is proposed the creation of a virtual environment, as a reproduction of the real one, which can be enjoyed by all categories of users.</p>