Assessment of the adaptive state of students based on the analysis of heart rate variability indicators

In the course of the study, the adaptive state of VlSU students was assessed by temporal, spectral, cardiointervalographic and integral indicators of heart rate variability. The characteristic of the state of the regulatory systems of students is given. The obtained results can serve as a certain addition to the understanding of the peculiarities of the process of adaptation of young students in the conditions of studying at higher school. Key words: heart rate variability (HRV), students, adaptation, regulatory systems, sympathetic and parasympathetic influence.

Features of changes in heart rate variability indices in driving school cadets with different levels of preparedness

The research was carried out on two independent experimental groups of boys and girls. The first was observed in traffic conditions, the second during the period of auto-simulator training. The HRV indices were determined: HR - heart rate, IN - index of tension of regulatory systems, AMo - amplitude of the mode, LF/HF - index of vagosympathetic interaction. A pronounced sympathetic reaction of more prepared cadets to the training load with the subsequent restoration of the studied characteristics was revealed. Key words: heart rate variability, autonomic regulation, vagosympathetic interaction, driver training, level of preparedness.

Assessment of the functional state of military men with different types of autonomic regulation in the midland’s conditions

The article presents the results of assessment and dynamic control over the functional state of military men in the midlands conditions. Depending on the initial type of autonomic regulation, groups with vagotonic (24%), sympatotonic (26%) and normotonic (50%) directions of regulatory processes were identified. It has been established that the state of optimal working voltage with more economical functioning of regulatory mechanisms is characteristic of carriages; for sympathotonics - an overstrain of regulatory mechanisms, and for normotonics - a moderate tension of regulatory systems with the mobilization of the functional reserves of the body. Key words: heart rate variability, functional state, types of autonomic regulation, midlands, military men.

Clinical case of heart transplantation in the conditions of «the recipient-to-donor» transportation

The main factor limiting the number of heart transplants in Ukraine is the small number of potential donors. In cases when the delivery time of the donor organ is more than 4 hours, the risks of the donor organ ischemic injury are multiplied. Transportation of the recipient to the location of the potential donor in such cases is a forced measure, as it increases the risk of adverse cardiovascular events in the recipient during transportation. Providing medical care to a recipient in such circumstances may be difficult. However, these measures are fully justified by the reduced risk of postoperative complications associated with the time of graft ischemia. The article describes a case of heart transplantation in the conditions of transporting the recipient to the donor. Heart transplantation was performed in a patient with NYHA functional class IV heart failure, refractory to conservative therapy. The postoperative period was uneventful. The time of cardiopulmonary bypass was 90 minutes, the total ischemia time was 180 minutes. On the 3rd day, the patient was transported to the specialized centre to continue treatment and rehabilitation. On the 21st day the patient was discharged in satisfactory condition for outpatient treatment. Key words: heart transplantation, cardiomyopathy, heart failure.

Heart Transplantation - Part II: Aspects of Procedure and Medical Management

Ischemic time, defined as the period from donor procurement to surgical implantation and restoration of intrinsic allograft function, is an independent risk factor for post-transplant mortality. In general, the ischemic time should be less than 4 hours. Most programs will accept donor hearts from within their own UNOS region or within a radius of 500 to 1000 miles to minimize ischemic time. Given the prevalent use of ventricular assist devices (VAD) as bridge to transplant and the increased time required to explant both the native heart and VAD hardware, patients must live within 2-3 hours (by car or air) of the transplant center. Coordinating the donor harvest and recipient preparation requires close collaboration between multiple surgeons, surgical teams and coordinators. This review contains 11 figures, 7 tables, and 52 references. Key words: heart transplant, immunosuppression, allograft rejection, infection, hypertension, hyperlipidemia, diabetes, malignancy, cardiac allograft vasculopathy, survival

Heart Transplantation - Part II: Aspects of Procedure and Medical Management

Ischemic time, defined as the period from donor procurement to surgical implantation and restoration of intrinsic allograft function, is an independent risk factor for post-transplant mortality. In general, the ischemic time should be less than 4 hours. Most programs will accept donor hearts from within their own UNOS region or within a radius of 500 to 1000 miles to minimize ischemic time. Given the prevalent use of ventricular assist devices (VAD) as bridge to transplant and the increased time required to explant both the native heart and VAD hardware, patients must live within 2-3 hours (by car or air) of the transplant center. Coordinating the donor harvest and recipient preparation requires close collaboration between multiple surgeons, surgical teams and coordinators. This review contains 11 figures, 7 tables, and 52 references. Key words: heart transplant, immunosuppression, allograft rejection, infection, hypertension, hyperlipidemia, diabetes, malignancy, cardiac allograft vasculopathy, survival

Heart Involvement in Inflammatory Rheumatic Diseases: A Systematic Literature Review

Introduction: Patients with inflammatory rheumatic diseases have an increased risk of developing cardiovascular manifestations. The high risk of cardiovascular pathology in these patients is not only due to traditional cardiovascular risk factors (age, gender, family history, smoking, sedentary lifestyle, cholesterol), but also to chronic inflammation and autoimmunity. Aim: In this review, we present the mechanisms of cardiovascular comorbidities associated with inflammatory rheumatic diseases, as they have recently been reported by different authors, grouped in electrical abnormalities, valvular, myocardial and pericardial modifications and vascular involvement. Methods: We conducted a systematic search of published literature on the following online databases: EBSCO, ScienceDirect, Scopus and PubMed. Searches were limited to full-text English-language journal articles published between 2010 and 2017 using the following key words: heart, systemic inflammation, autoimmunity, rheumatic diseases and disease activity. After the primary analysis we included 50 scientific articles in this review. Results: The results showed that cardiac manifestations of systemic inflammation can occur frequently with different prevalence in rheumatoid arthritis (RA), systemic lupus erythematosus(SLE), systemic sclerosis(SSc) and ankylosing spondylitis(AS). Rheumatologic diseases can affect the myocardium, cardiac valves, pericardium, conduction system and arterial vasculature. Conclusions: Early detection, adequate management and therapy of specific cardiac involvement are essential in rheumatic disease. Electrocardiographic and echocardiographic evaluation should be performed as routine investigations in patients with inflammatory rheumatic diseases.

Clinical Study of Patients with Heart Failure under treatment with Ozone Therapy.

Heart failure (HF) is framed in one of the types of cardiovascular diseases; it consists of an acute and chronic form. The disease can evolve slowly from asymptomatic left ventricular dysfunction, to a state of severe disability, presenting a wide prevalence in the population around 10% in people over 70 years old. More than three-quarters of the deaths from this pathology normally occur in low or middle-income countries. Angola is not exempt from this health problem be observed in a relatively young people, bringing disability and death at an early stage of life. Scientific advances and innovative treatments for the control and prevention of the disease continue to be insufficient. The ozone for it’s antioxidant, hemorheologic properties, oxygenation enhancers and blood circulation is an alternative treatment for these patients. We have performed a study where 45 patients who were diagnosed with a chronic stage of II-III HF due to the functional classification of the New York Heart Association (NYHA) and American Cardiology College / American Heart Association (ACC / AHA), previous echocardiogram with a Fracture of Left Ventricular Ejection (LVEF) less than 45%. We administered a Major Autohemotherapy with a protocol of 15 sessions, maintenance every 15 days and cycles every 6 months at 50?g of concentration, an initial dose of 4,000 ?g / ml up to 12,000?g / ml during the 3 years of treatment. Patients after the first treatment cycle improve their functional physical capacity and LVEF increased to normal levels (55%). It was proved that Autohemotherapy is an adjuvant, viable and beneficial treatment in chronic HF. Key words: Heart failure (HF), Major Autohemotherapy, Ozone therapy, Fracture of Left Ventricular Ejection

Testosterone treatment in chronic heart failure. Review of literature and future perspectives

Mounting evidence suggests that hormonal deficiencies (HD) have an important role in chronic heart failure (CHF). In particular, androgen depletion is common in men with CHF and is associated with increased morbidity and mortality. This review summarizes the current understanding of the complex relationship between CHF and testosterone, focusing on evidence derived from clinical trials that have investigated the role of testosterone in the treatment of CHF. A greater comprehension of this area will allow researchers and clinicians to plan future studies that improve current strategies to reduce mortality in this high-risk population. Online databases PubMed (Medline), Web of Science, and Scopus were searched for manuscripts published prior to June 2018 using key words "heart failure" AND "testosterone" OR "anabolism" OR "hormone" OR "replacement treatment”. Manuscripts were collated, studied and carried forward for discussion where appropriate. In summary, findings from the literature demonstrate that testosterone treatment in CHF is a promising topic that requires further investigation.

Blood circulation in the tunicate Corella inflata (Corellidae).

The ascidian tunicate Corella inflata is relatively transparent compared to other solitary tunicates and the circulatory system can be visualized by injecting high molecular weight fluorescein labeled dextran into the beating heart or the large vessels at the ends of the heart. In addition, after staining with neutral red the movement of blood cells can be followed to further define and characterize the circulatory system. The heart is a gently curved tube with a constriction in the middle and extends across the width of the animal. As in other tunicates, pumping is peristaltic and periodically reverses direction. During the abvisceral directional phase blood leaves the anterior end of the heart in two asymmetric vessels that connect to the two sides of the branchial basket (or pharynx), in contrast to the direct connection between the heart and the endostyle seen in the commonly studied tunicate Ciona intestinalis. In Corella inflata blood then flows in both transverse directions through a complex system of ducts in the branchial basket into large ventral and dorsal vessels and then to the visceral organs in the posterior of the animal. During the advisceral phase blood leaves the posterior end of the heart in vessels that repeatedly bifurcate to fan into the stomach and gonads. Blood speed, determined by following individual cells, is high and pulsatory near the heart, but decreases and becomes more constant in peripheral regions. Estimated blood flow volume during one directional phase is greater than the total volume of the animal. Circulating blood cells are confined to vessels or ducts in the visible parts of the animal and retention of high molecular weight dextran in the vessels is comparable to that seen in vertebrates. These flow patterns are consistent with a closed circulatory network. Additional key words: heart, pharynx, branchial basket, blood circulation, blood velocity