The Evolving Role of External Forcing in North Atlantic SST Variability Over the Last Millennium

Atlantic Multidecadal Variability (AMV) impacts temperature, precipitation, and extreme events on both sides of the Atlantic basin. Previous studies with climate models have suggested that when external radiative forcing is held constant, the large-scale ocean and atmosphere circulation are associated with sea-surface temperature anomalies that have similar characteristics to the observed AMV. However, there is an active debate as to whether these internal fluctuations driven by coupled atmosphere-ocean variability remain influential to the AMV on multidecadal timescales in our modern, anthropogenically-forced climate. Here we provide evidence from multiple large ensembles of climate models, paleo reconstructions, and instrumental observations of a growing role for external forcing in the AMV. Prior to 1850, external forcing, primarily from volcanoes, explains about one third of AMV variance. Between 1850 and 1950, there is a transitional period, where external forcing explains half of AMV variance, but volcanic forcing only accounts for about 10% of that. After 1950, external forcing explains three quarters of AMV variance. That is, the role for external forcing in the AMV grows as the variations in external forcing grow, even if the forcing is from different sources. When forcing is relatively stable, as in earlier modeling studies, a higher percentage of AMV variations are internally generated.

Enhanced Quaternary Exhumation in the Central Three Rivers Region, Southeastern Tibet

The roles of tectonics and climate in the global increased erosion rates during the Quaternary have been the subject of active debate. The Three Rivers Region, strongly influenced by continental convergence between India and Eurasia and change in Asian monsoon climate, is an ideal place to study the interactions between tectonics and surface processes. Here we report new apatite (U-Th)/He data from an elevation transect that reveal a phase of rapid exhumation since ∼2.6 Ma in the Dulong batholith in the central Three Rivers Region, southeastern Tibetan Plateau. Based on stream profile analysis and compiled thermochronological data in the region, we demonstrate that the tectonic uplift caused by the high-strain at the corner of Indian-Eurasia convergence is responsible for the enhanced exhumation in the central Three Rivers Region in the Quaternary. Our new results highlight that the continuous plate convergence towards the plateau interior has dominated the uplift and deformation in the southeastern Tibet in the Quaternary.

Quantifying Critical Success Factors (CSFs) in Management of Investment-Construction Projects: Insights from Bayesian Model Averaging

The problem with evaluating investment projects is that there are many factors that determine the degree of their successful conclusion. Consequently, there has been an active debate for years as to which critical success factors (CSFs) contribute most to the performance of construction projects. This is because the practice of empirical research is based on two steps: first, researchers choose a particular model from the space of all possible models, and second, they act as if the chosen model is the only one that fits the data and describes the phenomenon under study. Hence, there are many CSF lists that can be found in the literature, owing to the uncertainty at the model selection stage, which is usually ignored. Alternatively, model averaging accounts for this model uncertainty. In this study, the Bayesian model averaging and data from a survey of Polish construction managers were used to investigate the potential of 28 factors describing a diverse set of characteristics in explaining the performance of construction projects in Poland. Determinants of successful completion of investment projects are categorized by their level of evidential strength, which is derived from posterior inclusion probabilities (PIPs), i.e., providing strong, medium and weak evidence.

Attention and distraction in the predictive brain

Whether it is possible to ignore a physically salient distractor has been topic of active debate over the past 25 years, with empirical evidence for and against each of the theoretical stances. We put forward that predictive processing may provide a unified theoretical perspective that can account reasonably well for the empirical literature on attentional capture. In this perspective, capture is a logical consequence of the overall imperative of the brain to predict what sensory signals provide precise information to achieve goal-directed behavior.

Let's get physical – mechanisms of crossover interference

ABSTRACT The formation of crossovers between homologous chromosomes is key to sexual reproduction. In most species, crossovers are spaced further apart than would be expected if they formed independently, a phenomenon termed crossover interference. Despite more than a century of study, the molecular mechanisms implementing crossover interference remain a subject of active debate. Recent findings of how signaling proteins control the formation of crossovers and about the interchromosomal interface in which crossovers form offer new insights into this process. In this Review, we present a cell biological and biophysical perspective on crossover interference, summarizing the evidence that links interference to the spatial, dynamic, mechanical and molecular properties of meiotic chromosomes. We synthesize this physical understanding in the context of prevailing mechanistic models that aim to explain how crossover interference is implemented.

Paediatric Flatfeet - a 2020 guide for clinicians to identify the 'Boomerangs'

The paediatric flatfoot has long occupied a place in the medical literature, with concerns about the significance of its appearance. At the end of the first decade of the 21st century, a paper in this journal provoked active debate about the paediatric flatfoot as part of development, and proposed a considered titration of presenting cases in effort to justify treatment and appreciated the range and expected change in normal foot posture with growth. A decade later, the availability of normative paediatric foot posture data, and the prospective findings to confirm lessening flatfeet with age, encourage a structured and considered approach to this frequent primary care presentation. The pragmatic concept of the boomerang is built upon the research identifying the paediatric flatfeet likely to be symptomatic, thus requiring intervention, and filtering from those likely to remain asymptomatic. Differential diagnoses are advisedly considered, and gait remains the hallmark outcome. In this contemporary guide, an eight step strategy has been developed to improve the approach to community paediatric flatfeet concerns. Further, the three 'boomerang' flatfeet factors delineating symptomatic from asymptomatic flatfeet, and applicable cut-off levels, are availed for practical reference and use. Given the recognised state of overdiagnoses and resulting unnecessary treatment that pervades the 21st century, it is timely for clear '20:20' vision for the presentation of the paediatric flatfoot.

Reproductive toxicants in the environment and their role in some human diseases (Сlinic)

In recent decades, there has been a fairly active debate on the role of genetic predisposition, average factors, adverse effects of reproductive toxins, infections, special behaviour that includes harmful habits for human diseases and not to implement their reproductive plans. Environmental disasters, the Covid-19 pandemic, the incorporation of the modern human and industrial waste, forest fires, excessive radiation following the national tragedy of Chernobyl has become global, not only the age of dependent diseases, but the disorders of the main functional systems of the female and male organism that result in reproductive function, reduce the quality of life and duration. Unfavourable medium effects, disturb the process of interacting with the genotype of the organism in shaping the phenotype. This information is needed by doctors to develop periconceptology, which is the task of this clinical lecture.

Disabled people and the labor market in the 1950s: the Japanese experience

Outbreaks of war create large numbers of disabled people. After Japan's defeat in World War II, the Japanese government, under the policy of GHQ, began to create labor policies for disabled soldiers and the general disabled. However, historical research on the labor market participation of the disabled in Japan has not progressed. This study examines the job placement program for the physically disabled in the immediate postwar period. The end of the war encouraged the participation of people with disabilities in the labor market. In the early 1950s, the Ministry of Labor actively tried to find jobs for the disabled to improve the lives of disabled soldiers and bring new labor market participation to disabled people. This research revealed an active debate on whether the participation of disabled people in the labor market should be promoted by coercive state policies requiring companies to hire people with disabilities or by public support. Through analysis of the labor market for disabled people in 1950s, we will provide hints for deeper thinking about who the workers are and what it means to work in our society.

PENGEMBANGAN PERANGKAT PEMBELAJARAN MODEL DEBAT AKTIF PADA MATERI PEMANASAN GLOBAL UNTUK SISWA KELAS XI SMA

ABSTRAK Berdasarkan hasil obesrvasi yang dilakukan disekolah, perangkat pembelajaran yang digunakan guru belum tersusun dengan baik dan belum menggunakan instrumen penilaian yang sesuai dengan model pembelajran yang digunakan. Penelitian ini bertujuan untuk menghasilkan perangkat pembelajaran model debat aktif pada materi pemanasan global untuk kelas XI SMA. Penelitian ini menggunakan metode penelitian research and development dengan model Sugiyono Level 1. Adapun tahapan-tahapan yaitu potensi dan masalah, studi literatur dan pengumpulan informasi, desain produk, validasi desain dan perbaikan desain. Validasi produk dilakukan oleh 3 ahli yang ditinjau dari 3 aspek yaitu aspek penyajian, aspek isi dan aspek kebahasaan. Berdasarkan hasil uji validasi aspek penyajian didapatkan persentase sebesar 75,5% dengan kategori valid, aspek isi didapatkan persentase sebesar 81,6% dengan kategori sangat valid, aspek kebahasaan didapatkan persentase sebesar 83,3% dengan kategori sangat valid. Berdasarkan hasil tersebut, dapat disimpulkan bahwa perangkat pembelajaran model debat aktif pada materi pemanasan global untuk kelas XI SMA yang dihasilkan sudah valid/layak untuk diujicobakan dengan persentase rata-rata sebesar 80,13%.Kata kunci : Perangkat Pembelajaran, Debat Aktif, Berpikir Kritis, Berargumentasi ABSTRACT Based on the results of observation carried out in school, the learning tools used by teachers were not well structured and did not use assessment instruments that are in accordance with the learning model used. This study aimd to produced an active debate model of learning tools on the subject of global warming for high school class XI. This research used research and development method with Sugiyono Level 1 model. The stages were potential and problems, literature study and information gathering, product design, design validation and design improvement. Product validation was carried out by 3 experts reviewed from 3 aspects namely presentation, content and linguistic aspects. Based on the results of the validation test of the presentation aspect obtained a percentage of 75.5% with a valid category, the content aspect obtained a percentage of 81.6% with a very valid category, the linguistic aspect obtained a percentage of 83.3% with a very valid category. Based on these results, it can be concluded that the active debate model of learning tools on the matter of global warming for high school class XI produced is valid / feasible to be tested with an average percentage of 80.13%.Keywords : Learning Tools, Active Debate, Critical Thinking, Arguing

A Matter of Life and Death

This chapter addresses the life of COVID-19 data, how it has been used to reshape our daily lives by directing intervention measures, and how new data-driven technologies have been deployed to try and help tackle the spread of the coronavirus. Specifically, it examines infection and death rates and the use of surveillance technologies designed to trace contacts, monitor movement, and regulate people's behaviour. The use of these technologies raised questions and active debate concerning the data life cycle and their effects on civil liberties and governmentality. Indeed, most of the critical analysis of contact tracing apps focused on its potential infringement of civil liberties, particularly privacy, since they require fine-grained knowledge about social networks and health status and, for some, location. The concern was that intimate details about a person's life would be shared with the state without sufficient data protection measures that would foreclose data re/misuse and ensure that data would be deleted after 14 days (at which point it becomes redundant) or stored indefinitely.