multidisciplinary analysis
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2022 ◽  
Author(s):  
Gerald G. Carrier ◽  
Guillaume Arnoult ◽  
Nicolo Fabbiane ◽  
Jean-Sebastien Schotte ◽  
Christophe David ◽  
...  

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Sarahí Cruz Salazar ◽  
Marcio Adriano Anselmo

Purpose The purpose of this paper is to analyze the effectiveness of the Financial Action Task Force (FATF’s) recommendations in Latin America in the fight against Money Laundering (ML) through the Immediate Outcomes 4 (Preventive Measures) and 6 (Financial Intelligence) and the relationship between anti-money laundering (AML) effectiveness and anti-corruption measures. Design/methodology/approach Through quantitative and quality methods measure the performance of the Immediate Outcomes’ levels in compliance with the established FATF’ standards; The objective is to analyze progress in the prevention and identification of ML. Findings The authors discuss the relationship between AML effectiveness and anti-corruption measures starting with the analysis of the best-ranked country in these indicators (IO4 and IO6). Research limitations/implications Mutual evaluations require a long process, which is why the authors do not have all the updated data for all the Latin American countries; only the updated Immediate Outcomes data up to September 16, 2021, are taken. This paper is part of the Research Project “The impacts of corruption in the Western Hemisphere and regional responses.” Originality/value Through a multidisciplinary analysis, the Immediate Results evaluation model is prioritized to measure the effectiveness of the methods applied in Latin America through the IO4 and IO6. The model that presents the best effectiveness is selected and the successes that this country is applying over its peers are analyzed. From this analysis, a quantitative and qualitative analysis can be appreciated.


Minerals ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 1397
Author(s):  
Francisco Ruiz ◽  
Manuel Pozo ◽  
María Luz González-Regalado ◽  
Joaquín Rodríguez Rodríguez Vidal ◽  
Luis Miguel Cáceres ◽  
...  

This paper presents the easternmost mineralogical and geochemical evidence of the 1755 Lisbon tsunami found in the Western Mediterranean. This multidisciplinary analysis of a sediment core obtained in Gibraltar (southern Iberian Peninsula) has allowed us to differentiate a tsunamiite from an old lagoon (The Inundation). This tsunamigenic layer has increased levels of calcite and aragonite and higher concentrations of Ba and ferromagnesian elements in comparison with the underlying lagoonal sediments of this core. This layer is also differentiated by its paleontological record, with the introduction of marine species within this lagoon. The uppermost part of the core includes a transition from swampy/marsh paleoenvironments to terrestrial scenarios, with a final anthropogenic filling occurring during the last century.


2021 ◽  
Author(s):  
Jingsong Zhang ◽  
Jessica Cunningham ◽  
Joel Brown ◽  
Robert A Gatenby

Background We present a multidisciplinary approach to clinical trial design and analysis in a pilot study (NCT02415621) in which evolution-based mathematical models guide patient-specific dosing for Abiraterone treatment in men with castrate resistant metastatic prostate cancer. Methods Abiraterone plus prednisone were administered intermittently based on an evolutionary mathematical model. Outcomes are compared to historical controls and a matched contemporaneous cohort who met trial eligibility but received SOC dosing. Longitudinal cohort data allowed modification of pre-trial model parameter estimates. Model simulations of each patient using updated parameters critically evaluated trial design. Results Trial patients, on average, received no abiraterone during 59% of time on treatment. Median Time to Radiographic Progression (TTP) was 30.4 months compared to 14.3 months in the contemporaneous SOC group (p<0.001). All patients in the SOC group have progressed but 4 in the adaptive cohort remain on treatment at >1800 days. Longitudinal trial data found the competition coefficient ratio (αRS/αSR) of sensitive and resistant populations, a critical factor in intratumoral evolution, was 2 to 3-fold higher than pre-trial estimates. Computer simulations using the corrected parameter unexpectedly demonstrated optimal cycling can reduce the resistant cells. Longitudinal data from 4 trial patients who remain on treatment are consistent with model predictions. Modeling results predict protocol changes that will allow similar outcomes in most patients. Conclusions Administration of abiraterone using evolution-based mathematical models decreased drug dosing and increased radiographic TTP. Integration of mathematical models into trial design identifies novel insights into key treatment parameters and provides optimization strategies for follow-up investigations.


2021 ◽  
pp. 101967
Author(s):  
Alan A. Ahi ◽  
Noemi Sinkovics ◽  
Yelnur Shildibekov ◽  
Rudolf R. Sinkovics ◽  
Nikolay Mehandjiev

Author(s):  
Dmitry S. Korobov ◽  
◽  
Olga Yu. Chechetkina ◽  
Mariya B. Mednikova ◽  
◽  
...  

The comprehensive study of children's burials has become one of the most topical areas of archaeological research in recent decades. Peculiarities of the burial rites of juvenile individuals, their diseases and physical development parameters serve as an important indicator of the social status, reflecting as in a mirror the historical moment and specific cultural traditions. Our article presents the results of a study of an unusual child burial in archaeological context and anthropological data. It was carried out in a suburb on the periphery of barrow 876 in podpoi burial 2 of the Beslan kurgan catacomb cemetery (RNO-Alania), dating to the middle of the 7th century AD. Multidisciplinary analysis of the bone remains suggests that this 4-5 year old individual, with a bronze chain around his neck, at the time of burial had experienced repeated physiological stresses and significant physical exertion during his short life and was almost two times behind modern standards in terms of growth rate. But this child's head was intentionally deformed, and his frontal bone shows traces of extensive trepanation with no signs of healing, which does not rule out the high lifetime social status of this buried child and/or his parents.


2021 ◽  
Vol 12 (4) ◽  
pp. 95-101
Author(s):  
Bezhnar G. ◽  

The specificity of contemporary daily life is manifested in the interaction of mass culture with new media forms. Such interactions cause many social and cultural problems, one of which is marital well-being. The paper aims at studying the potential impact of digital space and social networks on marital relationship. The methodological basis of the study is a systematic approach to the study of social objects, interpretive research paradigm, multidisciplinary analysis. Information base of the research are monographs, articles, conference proceedings, reports, blogs. The search was conducted using the following keywords: mass culture, social networks, Internet, social media, digital space, marital relationship, mental health, psychological well-being, marital satisfaction. Social media offers a diverse experience for each user. The researchers state that this experience is largely positive that explains the growing use of social networks around the world. However, the use of social networks has its significant drawbacks and can threaten marital harmony. Danger factors are information that can arouse suspicion and uncertainty in a relationship; excessive control over partners in social networks, which destroys the sense of autonomy and privacy; excessive time spent in networks and intrusive signs of their use; disclosure of private information; insufficient privacy control; online adulteries that can cause divorce; feelings of worthlessness and dissatisfaction, which often arise as a result of comparing the personal offline reality with the online reality of the actors of communication processes and leads to frustration and depression.


2021 ◽  
Vol 12 (2) ◽  
pp. 45-41
Author(s):  
T. Kychkyruk ◽  
◽  
H. Salata ◽  

The modern world needs a new type of leader who develops a vision of the future for his / her followers and encourages them to be ready for it. These leaders ensure changes, they are not focused that much on the behavior of their followers / subordinates and on controlling their behavior. On the contrary, they are focused on the development of initiative and support becoming the servants of those they have to lead. The concept of servant l eadership is derived from the ideas of Robert K. Greenleaf. As R. Greenleaf states, it all starts with a natural urge – the desire to serve. The motto of this thought is "A good leader is primarily a servant". The task of the leader is to achieve common goals by ensuring the well-being of followers and subordinates. Servant leadership is an attempt to become better, to become the person others would gladly follow. Such an idealistic vision of a leader as a servant is fruitful and is paid off even in a very competitive business world. A servant leader builds an organized and creative team, and this type of leadership involves the development of organizational culture which demonstrates a high level of trust. Being a servant leader means to help people overcome obstacles and get the tools and resources they need to perform better; to be an example; to facilitate the work of others; to be willing to do what others do. This model of leadership implies a "flattening" of hierarchies: a boss is a friend who listens to those who are with him/her rather than a person who decides what is best for them. This type of leadership has the powerful potential in today’s globalized world. The article aims to analyze the concept of servant leadership. The authors have used an interpretive research paradigm and multidisciplinary analysis.


2021 ◽  
Vol 2042 (1) ◽  
pp. 012137
Author(s):  
T. Rakotoarivelo ◽  
F. Miranville ◽  
C. Gronfier ◽  
B. Malet-Damoui

Abstract Humans in the 21st century spend nearly 90% of their time in an indoor environment. This environment is far from the one in which humans have developed their physiological adaptation and regulation mechanisms. The indoor environment must be optimized for wellbeing and cognitive performance with an anthropocentric and multidisciplinary approach. The objective of this paper is to identify and evaluate the reliability of approaches to characterize thermal comfort in a humid tropical climate. To do so, we will present (i) an experiment conducted to evaluate this perception in a quantitative (physical measurements) and qualitative (field survey) way, and finally (iii) an intermodal and experimental comparison analysis. The results reveal some notable discrepancies between numerical approaches and experimental data. This finding reinforces our study perspectives on the need to engage a multimodal and multidisciplinary analysis to improve the accuracy of comfort models.


Toxicon X ◽  
2021 ◽  
pp. 100086
Author(s):  
Julien Potet ◽  
David Beran ◽  
Nicolas Ray ◽  
Gabriel Alcoba ◽  
Abdulrazaq Garba Habib ◽  
...  

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