Investigation of the Two-Mode Regime of Two-Gap Photonic-Crystal Resonance Systems Produced on a Printed Circuit Board with Fractal Elements "Minkowski Island

Introduction. The development of new amplifiers and generators of the Ku- and K-bands (12…27 GHz) for use in onboard equipment is increasingly attracting research interest. Low-voltage multi-beam klystrons (LMBK) can be a promising element base for such devices. Serious problems are associated with the need to suppress parasitic modes of oscillations in NMLK operating in the centimeter and millimeter range. A possible solution is to use double-gap photonic-crystal resonators (DPCR) in LMBK. Another promising direction for improving the characteristics of such resonators is to use resonant segments of strip lines with fractal elements. In this case, the strip lines are placed on a dielectric substrate in the interaction space. Such resonators exhibit new properties that are useful for klystrons (an increase in characteristic impedance, suppression of the spectrum of unwanted frequencies, a reduction in mass and dimensions).Aim. Determination of an optimal set of electrodynamic and electronic parameters of double-gap photonic-crystal resonance systems with fractal elements "Minkowski Island" when operated as part of the LMBK resonator system, excited on π- and 2π-modes of oscillation.Materials and methods. To calculate the electrodynamic parameters of resonators, the method of finite differences in the time domain was used. The well-known Wessel-Berg method was used to calculate electronic parameters, such as the Ge / G0 electronic conductivity and the coupling coefficient M.Results. The main electrodynamic parameters of the resonator – Q-factor, resonant frequency and characteristic impedance – were investigated. The electronic parameters of the resonator, the coefficient of coupling with the electron beam, and the relative electronic conductivity for π- and 2π-modes of oscillations were calculated. In this case, three variants of the resonator with zero, first and second iterations of the fractal element were investigated. The amplitude-frequency characteristics of the resonator were investigated with a change in the pitch of the photonic crystal lattice. An estimation of the inhomogeneity of the high-frequency field in the interaction spaces of the resonator was carried out. Operational conditions were determined simultaneously for two types of oscillations without self-excitation.Conclusion. The results can find application in the development of resonator systems for klystron-type devices in the centimeter and millimeter ranges.

Unsupervised Representation Learning for Proteochemometric Modeling

In silico protein–ligand binding prediction is an ongoing area of research in computational chemistry and machine learning based drug discovery, as an accurate predictive model could greatly reduce the time and resources necessary for the detection and prioritization of possible drug candidates. Proteochemometric modeling (PCM) attempts to create an accurate model of the protein–ligand interaction space by combining explicit protein and ligand descriptors. This requires the creation of information-rich, uniform and computer interpretable representations of proteins and ligands. Previous studies in PCM modeling rely on pre-defined, handcrafted feature extraction methods, and many methods use protein descriptors that require alignment or are otherwise specific to a particular group of related proteins. However, recent advances in representation learning have shown that unsupervised machine learning can be used to generate embeddings that outperform complex, human-engineered representations. Several different embedding methods for proteins and molecules have been developed based on various language-modeling methods. Here, we demonstrate the utility of these unsupervised representations and compare three protein embeddings and two compound embeddings in a fair manner. We evaluate performance on various splits of a benchmark dataset, as well as on an internal dataset of protein–ligand binding activities and find that unsupervised-learned representations significantly outperform handcrafted representations.

Kajian fenomena pandemi Covid-19 di Indonesia: Perspektif wacana, pengetahuan dan kekuasaan Foucault

Tujuan kajian ini untuk melihat pandemi Covid-19 di Indonesia sebagai fenomena sosial yang memberikan ruang interpretasi dari masyarakat dalam ruang aksi. Artikel ini merupakan kajian dalam melihat fenomena pandemi Covid-19 yang dianalisis secara kualitatif menggunakan perspektif wacana, pengetahuan dan kekuasaan dari Foucault. Hasilnya menunjukkan bahwa berbagai interpretasi dari masyarakat melibatkan tindakan nyata yang berkaitan dengan pemahaman tentang kekuasaan yang subjektif, horisontal, dan hadir dalam ruang interaksi publik yang melibatkan berbagai pihak. Melalui perspektif ini kita bisa lihat bagaimana kekuasaan bekerja melalui beragam mekanisme dalam ruang interaksi yang dilihat secara horizontal. Ruang tafsir relasi kekuasaan terkait fenomena pandemi Covid-19 di Indonesia memperlihatkan adanya tiga perhatian yang berbeda (relasi kekuasaan sebagai strategi, relasi kekuasaan govermentality, dan relasi kekuasaan dominasi).This study aims to see the Covid-19 pandemic in Indonesia as a social phenomenon that provides space for interpretation from the community in action space. This article is a study in looking at the Covid-19 pandemic phenomenon, which is qualitatively analyzed using the perspective of discourse, knowledge and power from Foucault. The results show that various interpretations of society involve concrete actions related to an understanding of power that is subjective, horizontal, and present in the public interaction space involving multiple parties. From this perspective, we can see how power works through various mechanisms in the interaction space seen horizontally. The interpretation room for power relations related to the Covid-19 pandemic phenomenon in Indonesia shows that there are three different concerns (power relations as a strategy, governmental power relations, and dominance power relations).

The Origins of Cyberspace

‘Cyberspace’ is a romantic term, introduced in the elegant science-fiction writing of William Gibson, but the concepts that make up the environment called ‘cyberspace’ are the stuff of real science, with origins that can be traced to ancient Greece. Much has been written about the origins of cyberspace, including a comprehensive sourcebook by Hook and Norman. This chapter tries to take a rather conceptual view of what constitutes cyberspace, tracing the origins of the ideas from fourth-century BCE Greece to the modern Internet-supported interaction space—throughout the discussion, the chapter will seek to elucidate the concept of ‘space’ and how it helps us to think about the cyber-world. On the way, the chapter considers the literary origin of the word, and the mathematical and logical theory that is required to build models of cyberspace.

The MADE-Axis

Tangible controls-especially sliders and rotary knobs-have been explored in a wide range of interactive applications for desktop and immersive environments. Studies have shown that they support greater precision and provide proprioceptive benefits, such as support for eyes-free interaction. However, such controls tend to be expressly designed for specific applications. We draw inspiration from a bespoke controller for immersive data visualisation, but decompose this design into a simple, wireless, composable unit featuring two actuated sliders and a rotary encoder. Through these controller units, we explore the interaction opportunities around actuated sliders; supporting precise selection, infinite scrolling, adaptive data representations, and rich haptic feedback; all within a mode-less interaction space. We demonstrate the controllers' use for simple, ad hoc desktop interaction,before moving on to more complex, multi-dimensional interactions in VR and AR. We show that the flexibility and composability of these actuated controllers provides an emergent design space which covers the range of interactive dynamics for visual analysis. In a user study involving pairs performing collaborative visual analysis tasks in mixed-reality, our participants were able to easily compose rich visualisations, make insights and discuss their findings.

River-Space Development as a Social Interaction Space through the Placemaking Approach

Urban water management has increasingly given the use of rivers to infrastructure, industry, and navigation; stripping away its use as a space and cutting people off while creating the phenomenon of social disconnection. Awareness to implement social planning during river development is important in order to integrate rivers into the urban fabric. This research examines the ‘City is Not a Tree’ theory as a basis to understand how cities need to have a semi-lattice structure with overlapping spaces in order to integrate themselves into the city. As the nature of this research is bottom-up, it saw appropriate the placemaking approach in creating river-spaces into a place for the people. Method used in this research includes analysis and comparison to theories, guides and ideal precedents. Furthermore, this research resulted in finding guides for creating good river-spaces through the placemaking approach. The guides are of elements and variables needed to create a good river-space and a guide for the required programs that need to be implemented. Through this research, it is found that developing river-spaces as a space to host social interaction with the placemaking approach, not only creates a livelier environment but also improves the overall quality of the river-space

Absolute quantitation of serum antibody reactivity using the Richards growth model for antigen microspot titration

In spite of its pivotal role in the characterization of humoral immunity, there is no accepted method for the absolute quantitation of antigen specific serum antibodies. We devised a novel method to quantify polyclonal antibody reactivity, which exploits protein microspot assays and employs a novel analytical approach. Microarrays with a density series of disease specific antigen were treated with different serum dilutions and developed for IgG and IgA binding. By fitting binding data of both dilution series to a product of two generalized logistic functions, we obtained estimates of antibody reactivity of two immunoglobulin classes simultaneously. These estimates are the antigen concentrations required for reaching the inflection point of thermodynamic activity coefficient of antibodies and the limiting activity coefficient of antigen. By providing universal chemical units, this method may improve standardization of serological testing, the quality control of antibodies and the quantitative mapping of antibody-antigen interaction space.

ИДЕНТИЧНОСТЬ И САМОПРЕЗЕНТАЦИЯ ЛИЧНОСТИ В ЦИФРОВЫХ МЕДИА. О КН.: ЛИСЕНКОВА А.А. ТРАНСФОРМАЦИЯ СОЦИОКУЛЬТУРНОЙ ИДЕНТИЧНОСТИ В ЦИФРОВОМ ПРОСТРАНСТВЕ: МОНОГРАФИЯ. ПЕРМЬ: ПЕРМСКИЙ ГОСУДАРСТВЕННЫЙ ИНСТИТУТ КУЛЬТУРЫ, 2021. 286 с.

Рецензия посвящена монографии, в которой осмысливается социально-культурные эффекты развития цифровых технологий в современном обществе, в частности степень их влияния на процессы идентификации и социализации. Автор рецензии отмечает, что особое внимание в данном издании уделено формированию социокультурной идентичности российской молодежи в пространстве новых медиа (в том числе социальных сетей), стратегиям и практикам репрезентации, формам публичной нарративизации и визуализации повседневного опыта. Виртуальная цифровая среда представлена в виде комплексного феномена, пронизывающего все сферы жизни человека, формирующего новые требования к его компетенциям, знаниям, умениям и навыкам, создающего не только интерактивное пространство взаимодействия, но и порождающего риски и угрозы нового порядка. Рецензируемая монография адресована широкому кругу читателей, включая культурологов, философов, специалистов по социальной и культурной антропологии, преподавателей и студентов гуманитарных вузов, всех кому интересны современные культурные процессы и различные аспекты развития цифрового общества. The review is devoted to the monograph, which comprehends the socio-cultural effects of the development of digital technologies in modern society, in particular, the degree of their influence on the processes of identification and socialization. The author of the review notes that special attention in this publication is paid to the formation of the socio-cultural identity of Russian youth in the space of new media (including social networks), strategies and practices of representation, forms of public narrativization and visualization of everyday experience. The virtual digital environment is presented as a complex phenomenon that permeates all spheres of human life, forming new requirements for his competencies, knowledge, skills and abilities, creating not only an interactive interaction space, but also generating risks and threats of a new order. The reviewed monograph is addressed to a wide range of readers, including cultural scientists, philosophers, specialists in social and cultural anthropology, teachers and students of humanities universities, all who are interested in modern cultural processes and various aspects of the development of a digital society.

DualRing

We present DualRing, a novel ring-form input device that can capture the state and movement of the user's hand and fingers. With two IMU rings attached to the user's thumb and index finger, DualRing can sense not only the absolute hand gesture relative to the ground but also the relative pose and movement among hand segments. To enable natural thumb-to-finger interaction, we develop a high-frequency AC circuit for on-body contact detection. Based on the sensing information of DualRing, we outline the interaction space and divide it into three sub-spaces: within-hand interaction, hand-to-surface interaction, and hand-to-object interaction. By analyzing the accuracy and performance of our system, we demonstrate the informational advantage of DualRing in sensing comprehensive hand gestures compared with single-ring-based solutions. Through the user study, we discovered the interaction space enabled by DualRing is favored by users for its usability, efficiency, and novelty.