Optimal Design of a BLDC Motor Considering Three-Dimensional Structures Using the Response Surface Methodology

In this paper, the optimal design of a brushless direct current motor with a three-dimensional (3D) structure using the response surface methodology (RSM) is presented. There were two optimization goals: reduction of the cogging torque and maintenance of the back electromotive force to prevent performance degradation. For motors with a 3D structure, a 3D finite element method analysis is essential, though it requires considerable computation time. Therefore, to reduce the optimal design time, the 3D structure was placed on the 2D plane. Thereafter, a 2D corrected model was applied to the RSM. For the validity of the technique, the analysis results of the initial 3D model, 2D model, and 2D corrected model were compared, and the results of the optimal design 3D model, 2D corrected model, and experiment were compared.

Type I and II PRMTs inversely regulate post-transcriptional intron detention through Sm and CHTOP methylation

Protein arginine methyltransferases (PRMTs) are required for the regulation of RNA processing factors. Type I PRMT enzymes catalyze mono- and asymmetric dimethylation; Type II enzymes catalyze mono- and symmetric dimethylation. To understand the specific mechanisms of PRMT activity in splicing regulation, we inhibited Type I and II PRMTs and probed their transcriptomic consequences. Using the newly developed Splicing Kinetics and Transcript Elongation Rates by Sequencing (SKaTER-seq) method, analysis of co-transcriptional splicing demonstrated that PRMT inhibition resulted in altered splicing rates. Surprisingly, co-transcriptional splicing kinetics did not correlate with final changes in splicing of polyadenylated RNA. This was particularly true for retained introns (RI). By using actinomycin D to inhibit ongoing transcription, we determined that PRMTs post-transcriptionally regulate RI. Subsequent proteomic analysis of both PRMT-inhibited chromatin and chromatin-associated polyadenylated RNA identified altered binding of many proteins, including the Type I substrate, CHTOP, and the Type II substrate, SmB. Targeted mutagenesis of all methylarginine sites in SmD3, SmB, and SmD1 recapitulated splicing changes seen with Type II PRMT inhibition, without disrupting snRNP assembly. Similarly, mutagenesis of all methylarginine sites in CHTOP recapitulated the splicing changes seen with Type I PRMT inhibition. Examination of subcellular fractions further revealed that RI were enriched in the nucleoplasm and chromatin. Together, these data demonstrate that, through Sm and CHTOP arginine methylation, PRMTs regulate the post-transcriptional processing of nuclear, detained introns.

Issues of the Risk-Based Approach

The purpose of the article was to analyze the problems currently standing in the way of more effective application of the risk-based approach methodology in the field of technogenic safety management. Methods — theoretical, inductive method, analysis of own experience, adopted normative legal acts, other publications. The main results of the work include the following: • despite the broadest use of the concept of “risk” in the field of technogenic safety management, there is no generally accepted interpretation of it to date; • often the evaluative concept of “risk” is mistakenly used instead of objectively existing risk factors; • quantifiably technogenic risk should be characterized by indicators of numerical nature, having vector objects, since two components should be indicated for the complete assignment of the indicator: the probability and the amount of damage; • experience shows that the methods of assessing the probabilistic component of risk indicators recommended by regulatory documents on the analysis and quantification of technogenic risk are accompanied by a very large uncertainty, therefore, instead of the traditional point statement, a more adequate method of assessment is the use of an interval approach that takes into account and allows quantifying this uncertainty; • the analysis showed that the so-called frequency approach, which is most often used to assess the probabilistic component of technogenic risk indicators, is used improperly, has no basis, since, as a rule, the phenomenon of statistical stability is not observed in the object area of the technosphere, there are no general aggregates; • in society and even among specialists, by now there is no understanding of the need to express all three components of damage from an accident (explosion/fire) in monetary terms, without which it is impossible to estimate and express the amount of total damage: — in conclusion, four key problems that hinder the more effective use of the risk-based approach methodology in the field of technogenic safety management are listed; — imperfection of the existing methodological base for the analysis and quantitative assessment of technogenic risk; — the problem of staffing in the field of technogenic risk management; — lack of national criteria for acceptable risk; — complete disregard of the problem of uncertainty of the results of the COR, the lack of methodological support for the procedure of analysis and quantification of this uncertainty. Conclusion — the efforts of the entire community of specialists-researchers, legislators, practitioners engaged in various aspects of the problem of technosphere safety management are necessary to solve the tasks specified in the article.

المناجاة في الأدب العربي النيجيري:دراسة أسلوبية لمناجاة زكريا إدريس أوبو حسين MUNAJAT IN NIGERIAN ARABIC LITERATURE: A STYLISTIC STUDY OF MUNAJAT OF ZAKARIYAU IDREES -- OBOH OSENI

الملخصهذا البحث يرصد دراسة مناجيات البروفيسور زكريا إدريس أوبو حسين، دراسة أسلوبية، للوقوف على قدرة الكاتب في رسم المشاهد المختلفة في حالات النفس الإنسانية، والكشف عن مستويات المناجيات النصية، والتقديم لدلالات ما خلف النص بوصفه نصاً أدبياً خاضعاً للقراءة والتأويل. وقد تناولت الدراسة كتب مناجاته في مستوياتها الصوتية والتركيبية والدلالية محاولة لإجراء الدراسة الأسلوبية عند كل مستوى، فقد أورد البروفيسور الاستعارات والتشبيهات والكنايات بشكل تفاعلي مع الجو الملائم لكل مناجاة، وأهمية هذا البحث تظهر في قلة أمثاله في المكتبات التي تستقري مثل هذه النصوص الإسلامية الشريفة، والتي تستحق لفت النظر. وتم تقسيم الدراسة إلى أربعة مباحث، سبقهم ملخص، ومقدمة، وفي الخاتمة تم تسجيل أهم النتائج فضلا عن المصادر والمراجع، والله المستعان. AbstractProfessor Zakariyau Idrees Oboh Oseni, is one of the prominent figures of Arabic and Islamic literature in Nigeria, working with University of Ilorin in Nigeria as an exemplary teacher, a writer and even a Critical critic. His poetic talent, literary ability, linguistic wealth, knowledge of the Noble Qur’an and the Prophet’s Sunnah, made him succeed in the Art of Munajat, and succeed as a sincere scholar who raises the nation a high-level education. This Research aims to study the Munajat (Monologues) of Professor Zakariyau Idrees Oboh Oseni as a stylistic study, to determine the writer›s ability to draw different scenes in cases of the human soul, to reveal the levels of textual Monologues, and to present the implications of what is behind the text as a literary text subject to reading and interpretation. The Study dealt with his Monologue books in their phonetic, structural and semantic levels, an attempt to conduct a stylistic study at each level. This approach includes a set of principles and procedures that aid the study of the text as a scientific study, through method analysis. The research is divided into three sections, preceded by a summary, followed by a conclusion.

THE ISSUES OF EVIDENCE FACILITATION IN THE REGULATION OF PACKAGE TRAVEL AND HOTEL SERVICES IN THE CONTEXT OF PROTECTING TRAVELLERS AND TOURISTS

Purpose. The aim of the article is to show the significance and diversity of legal constructions concerning the facilitations of proof in provisions regulating package travel and hotel services in the context of protecting travellers and tourists. Method. Analysis regarding the regulation of package travel and hotel services including the facilitations of proof are carried out using the formal-dogmatic and legal comparison method. The comparative method has a significant meaning for the proper interpretation of provisions regulating package travel and hotel services due to the interpenetration of national and international regulations. In the process of recreating norms from legal provisions, it is therefore helpful to analyse their similarities and differences. Findings. The provisions regulating package travel and hotel services include the facilitations of proof which improve the legal situation of travellers and tourists, as well as ensuring their protection. Research and conclusions limitations. There is no comprehensive study on facilitations of proof in the regulation of package travel and hotel services in literature on the subject. Practical implications. Conclusions resulting from the article will allow to determine the proper nature of the provisions referring to the facilitations of proof in the regulation of package travel and hotel services, which will enable their proper application in practice. Originality. The issue of the facilitations of proof in the regulation of package travel and hotel services has not been comprehensively researched so far. Type of work. Problem article.

THE EFFECT of PROMOTION on IMPULSIVE BUYING with LIFESTYLE as a MODERATION VARIABLE on FASHION PRODUCTS in ONLINE SHOP SHOPEE

The purpose of this study was to explain the effect of promotion on impulsive buyers and to explain that people with high lifestyles often make impulse purchases. Sampling using incidental sampling technique, the number of respondents as many as 100 respondents. The data collection method used is the observation method and the questionnaire method. Analysis of the data used is a multiple linear regression analysis with moderating variables using the SPSS program. The results of the study prove that promotion has a direct effect on impulse buying and it is not proven that people with a high lifestyle are more likely to make impulsive purchases.

THE EFFECT of PROMOTION on IMPULSIVE BUYING with LIFESTYLE as a MODERATION VARIABLE on FASHION PRODUCTS in ONLINE SHOP SHOPEE

The purpose of this study was to explain the effect of promotion on impulsive buyers and to explain that people with high lifestyles often make impulse purchases. Sampling using incidental sampling technique, the number of respondents as many as 100 respondents. The data collection method used is the observation method and the questionnaire method. Analysis of the data used is a multiple linear regression analysis with moderating variables using the SPSS program. The results of the study prove that promotion has a direct effect on impulse buying and it is not proven that people with a high lifestyle are more likely to make impulsive purchases.

The precedence conflict of Princes A.B. Trubetskoy and P.M. Shcheniatev in Polotsk in the spring of 1564: To the question of the position of the Trubetskoy's Princes in Moscow State on the Oprichnina's eve

The article attempts to identify the circumstances of the parochial conflict of the princes A.B. Trubetskoy and P.M. Shchenyatev in the Polotsk voivodeship in the spring of 1564, as well as the reasons for the final transition of the Trubetskoy princes to the sovereign service with the help of comparative and histotical method, analysis and synthesis, literature and sources on the investigated topic. As a result of the study, it was found that up to the 1560-ies the Trubetskoys occupied military and administrative posts sporadically and were not firmly embedded in the system of service relations of the Moscow state. Adopted in the early 1560s. the new land legislation jeopardized the further existence of the Trubetskoy estate and forced them to intensify their official activities. The conflict in Polotsk was the first attempt by the Trubetskoys to find out their real parochial status. Prince A.B. Trubetskoy was guided by the old ideas about the exclusive role of service princes, characteristic of the first third of the 16th century. He entered into a parochial dispute with an obviously superior enemy and did not emerge victorious from it. The author concluded that, faced with the new realities of the sovereign service, the Trubetskoys, who, due to their official passivity, were inferior to many less noble families in a parochial relation, sacrificed their relative independence and went over to the tsarist service. During the years of the oprichnina, they actively served in the oprichnina estate of Tsar Ivan the Terrible, won his favor and were able to raise their parochial status.

A Cluster Analysis Concerning the Behavior of Enterprises with E-Commerce Activity in the Context of the COVID-19 Pandemic

The planning of activities of e-commerce enterprises and their behavior has been influenced by the emergence of the COVID-19 pandemic. The behavior of e-commerce enterprises has been highlighted at the level of EU countries through an analysis elaborated on four variables: the value of e-commerce sales, cloud computing services, enterprises that have provided training to develop/upgrade the ICT skills of their personnel, e-commerce, customer relationship management (CRM) and secure transactions. Using the hierarchical clustering method, analysis was carried out on these variables to identify certain economic and behavioral patterns of e-commerce activity from 2018 and 2020. The study of the relationships involved in the e-commerce activity of these enterprises is reflected in models of the economic behavior of 31 European states in relation to the targeted variables. The results show that the impacts of the COVID-19 pandemic are strongly manifested in the direction of the evolution of each indicator but differ from one country to another. The trends depend on the level of development and the particularities of each country’s economy in adapting to the repercussions reported in relation to the level of impact of the COVID-19 pandemic. This is highlighted by the significant regrouping of countries in 2020 compared with 2018 in relation to the average values of the indicators. The results show that, in 2020, the most significant percentages of the value of e-commerce sales were recorded in Belgium, Ireland and Czechia, as in 2018. In e-commerce, customer relationship management and secure transactions, Denmark and Sweden were superior in 2020 to the countries mentioned above, which were dominant in 2018. For the other two indicators, Finland and Norway were the top countries included in the analysis in both years. The conclusion supports the continuous model of e-commerce enterprise behavior in order to meet the requirements of online customers.