scholarly journals AGATHIYAR KUZHAMBU (HERBO-MINERAL SIDDHA FORMULATION)

2021 ◽  
Vol 9 (4) ◽  
pp. 869-875
Author(s):  
Rakulini Raveendran ◽  
Sounthararajan Kalaiselvi ◽  
Sundararajan S
Keyword(s):  
Internal Medicine ◽  
Documentary Evidence ◽  
Pharmacological Activities ◽  
Therapeutic Uses ◽  
Croton Tiglium ◽  
Wide Range ◽  
Anti Inflammatory ◽  
Anti Fungal ◽  
Treatment Aspect ◽  
Hypertensive Activity

Introduction: Agathiyar kuzhambu (A.k) is a herbo-mineral siddha formulation. It is explained in the Siddha Vaith- iya Thiraddu Book. In Siddha Medicine, there are 32 internal & external medicines are explained in the Siddha Literatures. Agathiyar kuzhambu is a one form of the internal medicine which is commonly used in purgation ther- apy. It contains 11 ingredients. Agathiyar kuzhambu has different herbo- mineral ingredients which are having wide range of therapeutic uses. It is commonly used in Siddha OPDs. Aim: The researcher is going to develop the documentary evidence for the effectiveness of Agathiyar kuzhambu. Results and Discussion: Six ingredients herbs have hot potency and Pungent efficacy. These have many pharmacological actions. Commonly, these ingredients are possessed antioxidant, anti-microbial, hepatoprotective, anti-inflammatory, anti-fungal, anthelmintic, anti-dia- betic and anti -hypertensive activity. In Siddha, these ingredients and 5 minerals and metals ingredients were used in many disease conditions. Lots of adjuvants of Agathiyar kuzhambu have hot potency and pungent efficacy. Some of adjuvants have cool potency and sweet efficacy. In Siddha, these adjuvants were used in many disease conditions. Conclusion: According to the above study, Agathiyar kuzhambu may be act as stimulant and osmotic purgative at the same time it can use as a treatment aspect of many diseases. This study gives documentary evidence of Agathiyar kuzhambu as a purgative & possess many pharmacological activities in Siddha medicine. Keywords: Agathiyar kuzhambu, Siddha Medicine, Purgative, Croton tiglium

scholarly journals TERMINALIA CHEBULA: SUCCESS FROM BOTANY TO ALLOPATHIC AND AYURVEDIC PHARMACY

2016 ◽  
Vol 9 (5) ◽  
pp. 21
Author(s):  
Varun Garg ◽  
Barinder Kaur ◽  
Sachin Kumar Singh ◽  
Bimlesh Kumar
Keyword(s):  
Chemical Constituents ◽  
Present Review ◽  
Terminalia Chebula ◽  
Pharmacological Activities ◽  
Therapeutic Uses ◽  
Anti Cancer ◽  
Anti Oxidant ◽  
Anti Inflammatory

ABSTRACTTerminalia chebula (TC) is a unique herb having various therapeutic potentials as anti-inflammatory, antioxidant, anticancer, and digestant. It belongsto family Combretaceae. In the present review, an attempt has been made to decipher classification, chemical constituents, therapeutic uses, andpatents that have been reported for TC. Various pharmacological activities of TC that make it as potential medicine and its Ayurvedic formulationsare highlighted.Keywords: Terminalia chebula, Anti-oxidant, Anti-cancer, Ayurvedic formulations, Anti-oxidant.

scholarly journals Biochemistry, Safety, Pharmacological Activities, and Clinical Applications of Turmeric: A Mechanistic Review

2020 ◽  
Vol 2020 ◽  
pp. 1-14 ◽  
Author(s):  
Rabia Shabir Ahmad ◽  
Muhammad Bilal Hussain ◽  
Muhammad Tauseef Sultan ◽  
Muhammad Sajid Arshad ◽  
Marwa Waheed ◽  
...  
Keyword(s):  
Clinical Research ◽  
Biological Activities ◽  
Curcuma Longa ◽  
Clinical Applications ◽  
Pharmacological Activities ◽  
Neuroprotective Effects ◽  
Wide Range ◽  
Different Types ◽  
Safety And Toxicity ◽  
Anti Inflammatory

Turmeric (Curcuma longa L.) is a popular natural drug, traditionally used for the treatment of a wide range of diseases. Its root, as its most popular part used for medicinal purposes, contains different types of phytochemicals and minerals. This review summarizes what is currently known on biochemistry, safety, pharmacological activities (mechanistically), and clinical applications of turmeric. In short, curcumin is considered as the fundamental constituent in ground turmeric rhizome. Turmeric possesses several biological activities including anti-inflammatory, antioxidant, anticancer, antimutagenic, antimicrobial, antiobesity, hypolipidemic, cardioprotective, and neuroprotective effects. These reported pharmacologic activities make turmeric an important option for further clinical research. Also, there is a discussion on its safety and toxicity.

Saussurea lappa: A Comprehensive Review on its Pharmacological Activity and Phytochemistry

2020 ◽  
Vol 6 (1) ◽  
pp. 13-23
Author(s):  
Reyaz Hassan ◽  
Mubashir Hussain Masoodi
Keyword(s):  
Biological Activity ◽  
Adverse Effects ◽  
Chemical Constituents ◽  
Literature Survey ◽  
Perennial Herb ◽  
Comprehensive Review ◽  
Saussurea Lappa ◽  
Therapeutic Uses ◽  
Wide Range ◽  
Anti Inflammatory

Around 3000 species of Saussurea are known, however Saussurea lappa Clarke which is perennial herb and has been traditionally used as anticancer, anti-inflammatory, antiviral, medicine without many adverse effects. Phytochemistry of Saussurea lappa after thorough literature survey revealed various varied and copious metabolites such as sesquiterpenes, flavonoids, phytosterols, lignans, terpenes. Many of these compounds have been found to possess a wide range of biological activity such as anticancer, anti-inflammatory, anti-hepatotoxic, anti-viral, etc. Among sesquiterpenes particularly Dehydrocostuslactone, dihydrocostunolide, costunolide Lappadilactone, have been isolated as the main chemical constituents. This review aims to cover published work from public databases (e.g. PubMed, Google Scholar, ResearchGate) and Non-English, Ph.D./MS thesis databases (e.g. CKNIChina, Jairo-Japan, Myto-Malaysia, Shodhganga-India) with a particular focus on phytochemistry and therapeutic uses of different fractions as well as isolated compounds from Saussurea lappa.

scholarly journals A Review on Natural Plants for Phytochemical Constituents and Pharmacological Activities

2021 ◽  
Vol 11 (2) ◽  
pp. 232-236
Author(s):  
K Muni Raja Lakshmi ◽  
M. Kiran ◽  
K. Sai Prasanna
Keyword(s):  
Medicinal Plants ◽  
Antioxidant Properties ◽  
Volatile Oil ◽  
Calotropis Procera ◽  
Pharmacological Activities ◽  
Antioxidant Agents ◽  
Phytochemical Constituents ◽  
Natural Plants ◽  
Anti Inflammatory ◽  
Anti Fungal

The present review aims for the study of phytoconstituents and pharmacological activities of some natural plants. The traditional medicinal plants have been found to acquire therapeutic activities significantly antimicrobial, anti-inflammatory antibacterial, anti-fungal, antioxidant properties etc. The plant-derived constituents are majorly for the aliments of used skin disease diabetes, bronchitis, asthma, arthritis, dry cough, ulcer and fever. The antimicrobial activity of the following plants like Justicia adathoda, Lantana Camara, Acacia leucophloea, Holoptelea integrifolia, Calotropis Procera, chlorophytum tuberosum, Bombax ceiba, Bacopa monnieri, Wedelia trilobata, Jatropha gossypifolia were obtained from the extraction of either  leaves, stem or flowers by using ethanol, methanol, aqueous, petroleum ether, chloroform. The phytochemical constituents of the extract have been shown the presence of alkaloids, glycosides, cardiac glucosides tannins, proteins, carbohydrates, saponin, quinines, triterpenes, steroids, polyphenolic, volatile oil, phenols, starch sugar, amino acid, resin and organic acids. This study evidenced the possible use of the mentioned plants as a source of natural medicines which are used as an antimicrobial, anti-inflammatory, anti-bacterial, anti-fungal, antioxidant agents. Keywords:  Medicinal plants, Antimicrobial, Anti-inflammatory, Antioxidants.

scholarly journals Proceedings of Chemistry, Pharmacology, Pharmacokinetics and Synthesis of Biflavonoids

Molecules ◽  
2021 ◽  
Vol 26 (19) ◽  
pp. 6088
Author(s):  
Xinqian He ◽  
Fan Yang ◽  
Xin’an Huang
Keyword(s):  
Alzheimer’S Disease ◽  
Parkinson’S Disease ◽  
Alzheimer's Disease ◽  
Parkinson's Disease ◽  
Pharmacological Activities ◽  
Wide Range ◽  
Linear Fragment ◽  
Anti Inflammatory

Biflavonoids, composed of two monoflavonoid residues, occur naturally in angiosperms, bryophytes, ferns, and gymnosperms. More than 592 biflavonoids have been structurally elucidated, and they can be classified into two groups of C-C and C-linear fragments-C, based on whether the linker between the two residues contains an atom. As the linker can be established on two arbitrary rings from different residues, the C-C type contains various subtypes, as does the C-linear fragment-C type. Biflavonoids have a wide range of pharmacological activities, including anti-inflammatory, antioxidant, antibacterial, antiviral, antidiabetic, antitumor, and cytotoxic properties, and they can be applied in Alzheimer’s disease and Parkinson’s disease. This review mainly summarizes the distribution and chemistry of biflavonoids; additionally, their bioactivities, pharmacokinetics, and synthesis are discussed.

Benzimidazole: A Milestone in the Field of Medicinal Chemistry

2020 ◽  
Vol 20 (7) ◽  
pp. 532-565 ◽  
Author(s):  
Mahesh S. Vasava ◽  
Manoj N. Bhoi ◽  
Sanjay K. Rathwa ◽  
Divya J. Jethava ◽  
Prachi T. Acharya ◽  
...  
Keyword(s):  
Medicinal Chemistry ◽  
Benzimidazole Derivatives ◽  
Drug Candidate ◽  
Pharmacological Activities ◽  
Drug Candidates ◽  
The Future ◽  
Anti Inflammatory ◽  
Anti Fungal ◽  
Derivatives Of ◽  
Anti Hiv

In the last 2-3 decades, the broad research in the application of benzimidazole derivatives made it important for mankind. Many scientists have worked on benzimidazole derivatives and they found that this compound has a diverse role in the field of medicinal chemistry. Few benzimidazole derivatives are currently in the market as a drug candidate against various diseases. Moreover, the benzimidazole derivatives exhibit pharmacological activities such as anti-tuberculosis, anti-malarial, antihistamine, antimicrobial, antiviral, antidiabetic, anticancer, anti-fungal, anti-inflammatory, analgesic, anti-HIV, etc. In this review, we have summarized various derivatives of benzimidazole which have been prepared by many researchers to understand the chemistry as well as diverse pharmacological activities. These findings may lead the scientists who are working in the field of medicinal chemistry to the development of benzimidazole based drug candidates in the future.

Prunella vulgaris L: Critical Pharmacological, Expository Traditional uses and Extensive Phytochemistry: A Review

2021 ◽  
Vol 18 ◽  
Author(s):  
Reyaz Hassan Mir ◽  
Mohammad Faizan Bhat ◽  
Gifty Sawhney ◽  
Parveen Kumar ◽  
Nusrit Iqbal Andrabi ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Phenolic Acid ◽  
Research Literature ◽  
Biologically Active ◽  
Bibliographic Databases ◽  
Prunella Vulgaris ◽  
Volatile Oils ◽  
Therapeutic Uses ◽  
Wide Range ◽  
Anti Inflammatory

Background: Prunella vulgaris, family Lamiaceae also known as self-heal, has been traditionally used as an expectorant, anti-inflammatory, anti-pyretic, and anti-rheumatic. Due to widespread distribution of the plant, Vulgaris is also called ‘vulgar’ in Latin adjective meaning common. Objective: The objective of this review was to describe the relevant aspects of phytochemistry and therapeutic uses of different fractions as well as isolated compounds from Prunella vulgaris. An attempt was also made to enumerate the possible leads e.g. betulinic acid, oleanolic acid, ursolic acid, umbelliferone, scopoletin, esculetin, luteolin, homoorientin, Rosmarinic acid and cinaroside for further development. Method: For peer-reviewed research literature, we undertook a structured search of bibliographic databases using a focused review question. Scientific databases such as PubMed, Scopus, Science Direct, and Google Scholar were used Results: Phytochemistry of Prunella vulgaris (PV) after a thorough literature survey revealed varied and copious metabolites, such as triterpenoids, phenolic acid, sterols, carbohydrates, coumarins, fatty acids, and volatile oils. Many of these compounds have been found to possess wide range of biological activity per se, including anti-microbial, immunosuppressive, anti-cancer, cardio-protective, anti-allergic and anti-inflammatory. Conclusion: Prunella vulgaris is a medicinal plant of immense medicinal importance having a variety of compounds such as such as triterpenoids, phenolic acid, sterols, carbohydrates, coumarins, fatty acids, and volatile oils and diversity in pharmacological spectrum. The plant could be further exploited, to isolate the various biologically active constituents responsible for its activity.

scholarly journals Biological Activities and Phytochemical Constituents of Trailing Daisy Trilobata: A Review

2019 ◽  
Vol 9 (4-s) ◽  
pp. 888-892
Author(s):  
K Sai Prasanna ◽  
G Jyothi Reddy ◽  
M Kiran ◽  
K Thyaga Raju
Keyword(s):  
Skin Diseases ◽  
Biological Activities ◽  
Pharmacological Activities ◽  
Traditional System ◽  
Wedelia Trilobata ◽  
Anti Oxidant ◽  
Phytochemical Constituents ◽  
Anti Inflammatory ◽  
Anti Fungal ◽  
Natural Medicines

The traditional system of medicinal plants have been found to possess significant anti-inflammatory, antibacterial, anti-fungal, anti-diabetic, analgesic properties etc. Plant-derived drugs are used to cure mental illness, skin diseases, tuberculosis, diabetes, jaundice, hypertension, and cancer. Wedelia Trilobata belongs to family Asteraceae. Leaf, stem, and flower of Wedelia trilobata show anti-microbial, anti-oxidant and anti-inflammatory activity, analgesic activity. Phytochemical screening of the extract has been reported to show the presence of tannins, cardiac glycosides, flavonoids, terpenoids, phenols, saponins, and coumarins. Wedelia Trilobata is also used in reproductive problems, amenorrhea, chest cold, dry cough, and fever. The present review aims to the study was phytoconstituents, biological and pharmacological activities of Wedelia trilobata. This study suggested a possible use of Wedelia trilobata as a source of natural medicines as an anti-inflammatory, anti-oxidant, anti-microbial, hepatoprotective, antidiabetic agents. Keywords: Wedelia Trilobata, Trialing daisy trilobata, Complaya trilobata(L), Sphagneticola Trilobata, pharmacological review.

scholarly journals A review on Indole and Benzothiazole derivatives its importance

2019 ◽  
Vol 9 (1-s) ◽  
pp. 505-509 ◽  
Author(s):  
Shaheen Sulthana ◽  
P. Pandian
Keyword(s):  
Heterocyclic Compounds ◽  
Structural Modification ◽  
Biological Activities ◽  
New Product ◽  
Review Article ◽  
Literature Survey ◽  
Pharmacological Activities ◽  
Benzothiazole Derivatives ◽  
Wide Range ◽  
Anti Inflammatory

In recent years heterocyclic compounds analogues and derivatives have attracted wide attention due to their useful biological and pharmacological properties. Indole, Benzothiazole and its analogs are versatile substrates, which can be used for the synthesis of numerous heterocyclic compounds. Indole, Benzothiazole and its derivatives are used in organic synthesis and they are used in evaluating new product that possesses different biological activities. Hence, their extensive structural modification has result in different analogues of Indole and Benzothiazole derivatives depicting wide range of biological and pharmacological activities such as antiviral, anticonvulsant, anti-inflammatory, analgesic, antimicrobial and anticancer. This review article literature survey summarizes the synthesis and pharmacological activities of Indole, Benzothiazole and its derivatives. Keywords: Indole, Benzothiazole, antiviral, anticonvulsant, anti-inflammatory, analgesic, antimicrobial and anticancer

scholarly journals Mulinane- and Azorellane-Type Diterpenoids: A Systematic Review of Their Biosynthesis, Chemistry, and Pharmacology

Biomolecules ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 1333 ◽  
Author(s):  
Angel de Jesús Dzul-Beh ◽  
Andrés Humberto Uc-Cachón ◽  
Jorge Bórquez ◽  
Luis A. Loyola ◽  
Luis Manuel Peña-Rodríguez ◽  
...  
Keyword(s):  
Systematic Review ◽  
Natural Products ◽  
Medicinal Plants ◽  
Secondary Metabolites ◽  
Biological Properties ◽  
Pharmacological Activities ◽  
Wide Range ◽  
Anti Inflammatory

Mulinane- and azorellane-type diterpenoids have unique tricyclic fused five-, six-, and seven-membered systems and a wide range of biological properties, including antimicrobial, antiprotozoal, spermicidal, gastroprotective, and anti-inflammatory, among others. These secondary metabolites are exclusive constituents of medicinal plants belonging to the Azorella, Laretia, and Mulinum genera. In the last 30 years, more than 95 mulinanes and azorellanes have been reported, 49 of them being natural products, 4 synthetics, and the rest semisynthetic and biotransformed derivatives. This systematic review highlights the biosynthetic origin, the chemistry, and the pharmacological activities of this remarkably interesting group of diterpenoids.

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