Bioelement status of the body in overweight persons

The aim of the work is to assess changes in the bioelement status of overweight persons using the method of X-ray fluorescence analysis and to identify its correlations with nutritional features. It has been found that in a group of men with body mass index 25-30, the Ca/K ratio > 5 in 64 % of the surveyed, and the Zn/Cu ratio > 8 in 72 % of persons. Thus, it can be seen that in a group of men with increased body weight, the activity of calcium-regulating hormones is increased in 64%. In a group of women with body mass index 25-30, the Ca/K ratio > 5 in 92 % of the surveyed patients, and the Zn/Cu ratio > 8 in 56 %. It has been shown that with increased body weight, the activity of calcium-regulating hormones is increased in 92 % of the surveyed women. To construct the multiple regression equation, a matrix of paired correlation coefficients of factor levels is calculated and analyzed. The value of the Ca/K ratio in men is determined by the intake of potassium, calcium, iron, molybdenum, lead, and cadmium with food. The Ca/K ratio in women is determined by the intake of calcium, manganese, and sulfur with food. To normalize the work of calcium-regulating mechanisms, it is necessary to control the intake of these elements into the body.

Comprehensive approach to the tuberculosis indicators assessment of the children population in the Republic of Crimea

Introduction. Childhood tuberculosis (TB) control is relevant due to the peculiarities of its course in this age group, and the TB incidence in children is an important prognostic epidemiological indicator.Aim. Use of multivariate statistical analysis to estimate and predict childhood TB indicators in the Republic of Crimea (RC).Materials and methods. The official TB statistics in the Republic of Crimea for 2014-2018 are used. The calculated means of the indicators are checked for normality using the Kolmogorov-Smirnov and Shapiro-Wilk tests. Pearson correlation analysis is applied to determine pair correlation relationships. Stepwise multiple regression analysis is carried out to determine group conditionality of the indicators, where coefficients, with which significant pairwise correlations are found, are selected as independent variables. Based on the results, multiple regression equations are made to predict the values of dependent variables. The data is processed using Statistica 10.0 software.Results. For childhood TB incidence, strong direct correlations are established with the incidence and prevalence of pulmonary TB among children. The paired correlation coefficient between the incidence of childhood TB and childhood lung TB and the detection of active TB patients in preventive examinations of children varied in the range of 0.63-0.72. For the prevalence of TB among children, strong direct correlations were found with the incidence of TB and pulmonary TB in children. Multiple correlation coefficients for the incidence and prevalence of childhood TB exceeded the values of paired correlation coefficients and were in the range of 0.93 to 0.98 (p<0.001), indicating greater significance of group conditionality of the indicators. Determination coefficients R2 were between 0.87 and 0.96. Multiple regression models were built for the childhood TB incidence, childhood lung TB incidence, childhood TB prevalence, childhood lung TB prevalence.Conclusion. The found strong direct pairwise correlations for childhood TB incidence and prevalence and childhood pulmonary TB incidence and prevalence can serve as prognostic criteria and reflect the quality of antituberculosis interventions. High values of paired correlation coefficient between childhood TB incidence and childhood pulmonary TB and detection of patients with active TB in preventive examinations of children are a criterion of quality of both TB services and primary care, which can prevent the spread of TB and improve the epidemic situation of TB in Crimea. The calculated multiple regression models for the studied indicators can serve the needs of practical forecasting in Healthcare.

Financial solvency of the regions of the Russian Arctic.

The monograph is devoted to assessing the financial solvency of the regions of the Russian Arctic by means of correlation analysis aimed at studying the forms of communication between indicators that allow us to identify general and specific features of the financial development of regions. The work selected and analyzed statistical indicators that characterize directly or indirectly the financial solvency of the regions, calculated the correlations of these indicators, taking into account their dynamics over the past fifteen years. A matrix of correlation pairs was created, the most significant of them for assessing the financial solvency of the region were identified. Comparative analysis of paired correlation coefficients for the Arctic regions made it possible to assess the relationship between certain areas of their regional development. A comprehensive analysis of the financial solvency of the Arctic territories is presented, and based on the results obtained, trajectories of regional financial development are developed, considering background conditions. The results of the monograph are intended for a wide range of specialists in the field of regional finance and may be of interest to everyone who is interested in the problems of financial development, as well as to regional and federal authorities for forecasting and strategic planning of the development of the Arctic regions in conditions of limited financial resources.

Cadmium concentration in cattle tissues in the Czech Republic

The aim of this paper was to evaluate the cadmium concentrations in the muscles, liver, and kidney of three age categories (≤ 8 months; ≤ 2 years; ≥ 2 years) of cattle during the period of years 2014–2019 and to determine the age limit at which the concentration of cadmium in an organ with the highest accumulation increases health risk for consumers. In cattle above two years of age, there was a higher average cadmium concentration in the liver (0.10 mg/kg) and kidney (0.62 mg/kg), when compared with cadmium concentration in the liver (0.06 mg/kg) and kidney (0.24 mg/kg) of cattle under two years of age. A paired correlation coefficient r = 0.825 8 (P &lt; 0.006) and Spearman’s coefficient ρ = 0.92 (P &lt; 0.000 1) were calculated for the dependence of the cadmium concentration on the age. The correlation analysis statistically demonstrated a significant positive correlation between the concentration of cadmium in the kidney and the age of the cattle. A non-significant difference between the maximum limit and the average concentration of the cadmium in the kidney of the cattle from the age of 6 years (P = 0.029) was demonstrated using the t-test. The cadmium concentration in the muscles was low and was not significantly affected by the cattle’s age.

DEVELOPMENT OF REGIONAL MODELS OF CREATIVE INDUSTRIES ON THE BASIS OF CORRELATION-REGRESSION ANALYSIS

The article considers the importance of research and functioning of creative industries and substantiates the stages of integrated assessment of their development. One of the methodologi-cal approaches to the study of creative industries is considered namely correlation-regression analysis. The necessity of application of multiple correlation-regression analysis for estimation of the interdependence of certain creative indicators with their creative parameters is opened and the regional model of development of creative industries is constructed. The study is based on calculations and formulas, the values of which are used in the construction of a matrix of paired correlation coefficients and other important components. Based on the study, regression statistics and analysis of variance. The paper provides all possible indicators for the develop-ment of an organizational and economic mechanisms for building regional models of creative industries.

Evolution Under Domestication of Correlated Attributes in Two Edible Columnar Cacti in Mexico

Stenocereus pruinosus and S. stellatus are columnar cacti from central Mexico, distributed in the Valle de Tehuacán and the Mixteca Baja regions. Both species have populations subject to three different forms of human management: wild, in situ and cultivated, growing in sympatry. The objectives of the present study were to compare variation in damage levels, defense mechanisms and fitness components between 1) both species due to differences in the intensity of management; 2) populations of both species subject to different forms of management; 3) two regions with different management practices and physical conditions, in these two columnar cacti. We estimated the percentage of damage, abundance of spines as resistance, and branching rate as a tolerance component, number of fruits produced in one year, number of seeds per fruit and percentage of seed germination as fitness components. The differences between species, forms of management and regions were estimated with ANOVA tests. A paired correlation with the measured variables within each form of management was used to observe the correlated attributes in both species. We found differences between species, forms of management and regions, mostly concordant with the domestication syndromes. More managed populations, present more damage and less resistance, without compromising fitness, which is the target attribute. Correlated attributes exhibited significant correlations in both species and forms of management. Some of them were concordant with domestication syndrome: More damage/less resistance, or more damage/more branching rate. Our results show that human management can influence the evolution of the interaction of correlated attributes like defense mechanisms, damage and fitness in these columnar cacti.

The impact of the shadow economy on the country’s financial security

The article is devoted to determining the features of the shadow economy's impact on financial security. For this purpose the following are carried out: generalization of calculation indicators in the shadow economy; influence assessment level of the shadow economy on the volume of gross domestic product (further-GDP); based matrix paired correlation coefficients integral indicator of financial security and factors of shadow economy by various methods; conducted surveillance on the dynamics of the integral index of financial security and the level of the shadow economy, calculated using monetary means and integral measure of financial security of cash in UAH and the dollar; investigated the interconnection statistical indicators and indicators of financial security dynamics of cash in the economy; evaluated the safety performance of non-banking financial market and the volume of cash in dollar terms in dynamics; Then a matrix construction paired correlation coefficients tax rate component of financial security and the coefficients of the shadow economy, estimated by different methodological approaches; monitored security tax rate and share of loss-making enterprises and statistical significance is estimated regression equation pair of security and tax number of unprofitable enterprises.

Multiply Regression Analysis as An Integrated Approach in the TB Indicators Assessment in the Republic of Crimea

The use of multiply regression analysis for the TB indicators assessment and prediction in the Republic of Crimea is discussed. Basic TB indicators in the Republic of Crimea for the period 2014-2018 were studied using Pearson correlation coefficient and step-by-step multiply linear regression analysis. During paired correlation analysis, dependable association with an average and high degree is identified for the most indicators of interest. The multiple correlation coefficients were higher than the paired correlation coefficients, which demonstrated the greater significance of the group conditionality of the indicators. For key epidemiological TB indicators the regression equations are constructed and the most relevant predictors are found using stepwise multiply regression analysis. The regression equations for TB incidence, prevalence and mortality rates are proposed for practical applying to predict epidemiological situation.

Μελέτη παρατήρησης του επιπλέον οφέλους του ωτοβελονισμού σε ασθενείς με γλαύκωμα

Ο βελονισμός και o ωτοβελονισμός έχουν χρησιμοποιηθεί για την αντιμετώπιση του γλαυκώματος. Σκοπός της εργασίας είναι να μελετήσουμε εάν ο ωτικός ηλεκτροβελονισμός συμβάλει στην ελάττωση της ενδοφθάλμιας πίεσης (ΕΟΠ) και στη σταθεροποίηση της νόσου. Ασθενείς και μέθοδος: Τυχαιοποιημένη μελέτη σε ασθενείς με γλαύκωμα ανοιχτής γωνίας υπό αγωγή, μετά από έγκριση της Ε. Ε. του ΠΓΝΙ και έγγραφη ενημερωμένη συναίνεση των ασθενών. Κριτήρια εισαγωγής στην έρευνα: γλαύκωμα ανοιχτής γωνίας με πίεση (IOP) >21 mmHg, τοπική αντιγλαυκωματική θεραπευτική αγωγή για τουλάχιστον 3 μήνες (latanoprost), ηλικία ασθενών >25 έτη, ενυπόγραφη συναίνεση. Κριτήρια αποκλεισμού: οφθαλμική φλεγμονή, ασθενείς με χειρουργική επέμβαση για γλαύκωμα ή διαθλαστική διόρθωση, σοβαρή οπτική νευροπάθεια, προχωρημένη απώλεια οπτικού πεδίου, αντένδειξη στη διενέργεια ωτοβελονισμού, αρτηριακή υπέρταση. Στους ασθενείς της ομάδας Α προστέθηκαν επιπλέον σταγόνες δορζολαμίδης – τιμολόλης, στην ομάδα Β εφαρμόστηκε ωτικός ηλεκτροβελονισμός στα σημεία ήπαρ, νεφρός και οφθαλμός ανά 8 ημέρες τους 3 πρώτους μήνες και στη συνέχεια 1 φορά τον μήνα για 12 μήνες. Εκτός από τη μέτρηση της ΕΟΠ, έγιναν μετρήσεις με τη βοήθεια της Τομογραφίας Οπτικής Συνοχής πριν, 3 και 15 μήνες μετά την έναρξη της παρακολούθησης. Στατιστική: r = Pearson’s paired correlation, t=Student’s paired t-test, το, X2 =Friedman related variables, independent samples t- test και το general linear model – repeated measurements anova. Αποτελέσματα: Εξετάστηκαν 101 γλαυκωματικοί οφθαλμοί σε 60 ασθενείς, 50 στην ομάδα Α και 51 στην ομάδα Β. Δεν παρατηρήθηκαν σημαντικές διαφορές στην ηλικία των ασθενών μεταξύ των δύο ομάδων. Κατά τη σύγκριση των ομάδων παρατηρήθηκαν σημαντικές διαφορές στο πάχος της αμφιβληστροειδικής στιβάδας νευρικών ινών (AvgRNFL, AvginfRNFL) και στο πάχος του συμπλέγματος γαγγλιακών κυττάρων. Στην ομάδα δορζολαμίδης – τιμολόλης παρατηρήθηκε σημαντική μείωση της ενδοφθάλμιας πίεσης στους 3 και 15 μήνες, και ήπια αύξηση από τους 3 στους 15 μήνες. Δεν παρατηρήθηκε μεταβολή στις μετρήσεις με την τομογραφία οπτικής συνοχής. Στην ομάδα ηλεκτροβελονισμού παρατηρήθηκε σημαντική μείωση της ΕΟΠ σε όλα τα σημεία μέτρησης, στατιστικά σημαντική αύξηση του πάχους του συμπλέγματος γαγγλιακών στο ανώτερο και κατώτερο τμήμα (GCCsup, GCCinf) στους 15 μήνες, στατιστικά σημαντική μείωση νευροαμφιβληστοειδικού δακτυλίου (rim area) στους 3 μήνες και στατιστικά σημαντική μείωση του GLV στους 3 μήνες χωρίς περαιτέρω μεταβολή στους 15 μήνες. Συζήτηση: Τόσο οι επιπλέον σταγόνες στην αντιμετώπιση του γλαυκώματος, όπως και ο ωτικός ηλεκτροβελονισμός είχαν ως αποτέλεσμα την σταθεροποίηση της νόσου με υπεροχή της ομάδας επιπλέον φαρμάκου στην ελάττωση της ΙΟΡ. Διαφαίνεται ωστόσο μια τμηματική βελτίωση της στιβάδας γαγγλιακών κυττάρων από τους 3 έως τους 15 μήνες στους ασθενείς που έλαβαν επιπλέον ωτοβελονισμό, η οποία εικάζεται ότι παραπέμπει σε πιθανή νευροπροστασία.

FORECASTING THE VALUES OF ECONOMIC GROWTH FACTORS IN A REGION (A CASE OF THE UDMURT REPUBLIC)

The article deals with forecasting the values of economic growth factors in a region on the example of the Udmurt Republic. A statistically significant multiple linear regression equation (that explains the dynamics of the gross regional product from the signs-factors) is derived, a factorial forecast is developed and the results obtained are interpreted. Deflation method has been applied to eliminate the impact of price growth and GRP value has been calculated in 2007 prices. On the basis of multiple regression analysis, a matrix of paired correlation coefficients is calculated and informative factors of the model are selected. The significance of paired correlation coefficients is checked. The model is constructed in its natural form with informative factors only. The statistical significance of the regression coefficients is evaluated with the help of the Student's t -criterion, the quality of the equation is estimated through the average approximation error, which confirm the sufficiently high quality of the model. The predicted value of the result is calculated. It was found that if the current trends in the dynamics of these factors persist, we can expect the growth of real (physical volume) GRP over the period 2016-2020 by 26 % or 5.5 % annually, which meets the requirements of economic security of the region. The above information can be used to develop programs of regional economic development and design in the system of state and municipal administration.