Analysis of Oscillating Fishing Tool Efficiency for Stuck Assembly Recovery in Field X

As conventional fishing assembly offers a degree of recovery chance, such chance can be increased by utilizing an Oscillating Fishing Tool (OFT). The OFT is a fishing Bottom Hole Assembly (BHA) component that delivers low-magnitude; high-frequency oscillation. The continuous motion that the tool provides complements the impact generated by the fishing jar. This paper reviews the successful case history in Field X, which was in fact the first utilization of OFT for a fishing application in the field. Method of analysis involve comparing fishing sequence without and with the OFT. The OFT was used in Offshore Field X to recover a mechanically stuck 550-meter long Tubing Conveyed Perforating Gun assembly inside 9 5/8" casing that could potentially lead to loss of access into the 6 oil reserves candidate perforation zones. Initially the assembly had been stuck for two days, during which conventional fishing BHA was used to retrieve it to no avail, even after jarring for most of that time. OFT was then incorporated in the final fishing BHA and operated in combination with jarring operation. After around twelve hours of oscillating and jarring, the fish was able to be released from the initial stuck point. When tripping the string out, however, the assembly was stuck at high dog-leg severity area near the surface. At that point, in combination with applying substantial overpull, OFT was utilized further to recover the entire string. Upon fish retrieval, it was evident that post detonation, the TCP gun had swelled into 8.6 inches in diameter. In summary, oscillating and jarring for thirty-six cumulative hours successfully released the swelled TCP gun assembly from the stuck occurrences. In conclusion, the operation showed that the OFT serves as a higher level of fishing tool option that offers a particular excitation mode to the stuck assembly. Stuck assembly in a cased hole presents potential loss of oil reserves. Particularly in offshore application, the situation can also be costly. With reduced chance of recovery as time passes by, operation is hindered from being able to proceed to the next completion phase. The case proved OFT to have played an important role in improving fishing probability of success and should be considered as standard fishing BHA in the future.

Circulating miR-122-5p and miR-375 as Potential Biomarkers for Bone Mass Recovery after Parathyroidectomy in Patients with Primary Hyperparathyroidism: A Proof-of-Concept Study

Primary hyperparathyroidism (PHPT) is the leading cause of secondary osteoporosis. Although bone mineral density (BMD) tends to recover after parathyroidectomy in PHPT patients, the degree of recovery varies. Circulating microRNAs (miRNAs) profiles are known to be correlated with osteoporosis and fracture. We aimed to investigate whether osteoporotic fracture-related miRNAs are associated with postoperative BMD recovery in PHPT. Here, 16 previously identified osteoporotic fracture-related miRNAs were selected. We analyzed the association between the preoperative level of each miRNA and total hip (TH) BMD change. All 12 patients (among the 18 patients enrolled) were cured of PHPT after parathyroidectomy as parathyroid hormone (PTH) and calcium levels were restored to the normal range. Preoperative miR-19b-3p, miR-122-5p, and miR-375 showed a negative association with the percent changes in TH BMD from baseline. The association remained robust for miR-122-5p and miR-375 even after adjusting for sex, age, PTH, and procollagen type 1 N-terminal propeptide levels in a multivariable model. In conclusion, preoperative circulating miR-122-5p and miR-375 levels were negatively associated with TH BMD changes after parathyroidectomy in PHPT patients. miRNAs have the potential to serve as predictive biomarkers of treatment response in PHPT patients, which merits further investigation.

STUDY OF THE SORPTION OF AMMONIUM CATIONS ON A FIBROUS CARBOXYLIC SORBENT

Background: Wastewater from the mineral fertilizer production, agribusiness containing ammonium ions causes significant harm to fish farming; therefore, it must be purified before discharge. Ion-exchange sorption is a promising method for isolating ammonium cations. The object of the study was a chemisorption fiber VION KN-1, which has developed surface and high sorption rate. Purpose: To study the sorption kinetics of ammonium cations from aqueous solutions on VION KN-1; to train an ANN to predict the degree of recovery of ammonium ions from wastewater using Statistica Neural Networks Version 13. Methods: The ammonium ion concentration in the solution was established by direct potentiometry. Sorption isotherms were constructed using the method of variable concentrations. To determine the limiting stage, the obtained kinetic dependencies were represented in the coordinates of the Boyd-Adamson equations for internal/external diffusion. Results and Discussion: During sorption from solutions with different ammonium nitrogen contents, the values of distribution coefficients (Kd) are at the level of 2.3ꞏ103 cm3/g, which significantly exceeds this parameter for granular ionites. Experimental sorption data were verified using Freundlich (R2 = 0.9224) and Langmuir (R2 = 0.9996) isotherms. The maximum degree of recovery (over 96 %) was achieved by passing a solution with a concentration of 11.3 mmol/dm3. Using an array of experimental data, the MLP-3-5-1 neural network was trained. The coefficient of determination R2 = 0.999420 obtained for the training sample characterizes high network performance. Conclusions: The Langmuir equation better describes the process of NH4+ sorption on a fibrous sorbent. It is reasonable to use VION KN-1 at the fine treatment stage. Ammonium ion desorption from the fiber was performed by acid solution. The resulting solutions of ammonium salts can be used as liquid fertilizers. The trained neural networks can be used to predict the degree of recovery of ammonium ions by sorbent VION KN-1.

Differential DNA methylation in recovery from shift work disorder

The human DNA methylome is responsive to our environment, but its dynamics remain underexplored. We investigated the temporal changes to DNA methylation (DNAme) in relation to recovery from a shift work disorder (SWD) by performing a paired epigenome-wide analysis in an occupational cohort of 32 shift workers (25 men, age = 43.8 ± 8.8 years, 21 SWD cases). We found that the effect of vacation on DNAme was more prominent in the SWD-group as compared to controls, with respect to the amount of significantly differentially methylated positions (DMPs; Punadj < 0.05) 6.5 vs 3.7%, respectively. The vast majority (78%) of these DMPs were hypomethylated in SWD but not in controls (27%) during the work period. The Gene Ontology Cellular component “NMDA glutamate receptor” (PFDR < 0.05) was identified in a pathway analysis of the top 30 genes in SWD. In-depth pathway analyses revealed that the Reactome pathway “CREB phosphorylation through the activation of CaMKII” might underlie the recovery. Furthermore, three DMPs from this pathway, corresponding to GRIN2C, CREB1, and CAMK2B, correlated with the degree of recovery (Punadj < 0.05). Our findings provide evidence for the dynamic nature of DNAme in relation to the recovery process from a circadian disorder, with biological relevance of the emerging pathways.

SURGICAL TREATMENT OF PERIPHERAL NERVES COMBAT WOUNDS OF THE EXTREMITIES

The aim: Improving the effectiveness of patients' treatment with combat injuries of the peripheral nervous system, which consists in the application and development of new methods of reconstructive interventions, optimizing a set of therapeutic and diagnostic measures for the most effective management of this category of patients with peripheral nerve injury. Materials and methods: The research is based on the results of surgical treatment of 138 patients with combat injuries of peripheral nerves for the period from 2014 to 2020. The mean age was 33.5 ± 2.1 years. Patients were treated for 1 to 11 months after injury (median – 8 months). Damage to the sciatic nerve was observed in 26.1%, ulnar – in 20.3%, median – in 18.8%, radial – in 15.9%, tibial – in 10.9%, common peroneal nerve – in 8% of cases. Results: It was shown that in all patients was significantly improved the recovery of all nerves. In the period from 9 to 12 months, the degree of recovery of motor function to M0-M2 was observed in 40.6%, to M3 – in 35.5%, to M4 – in 16.7%, to M5 – in 7,2%. The degree of recovery of sensitivity to S0-S2 was observed in 36.2%, to S3 – in 42.8%, to S4 – in 17.4%, to S5 – in 3.6%. Regression of pain syndrome after surgery was observed in 81.2% of patients. Conclusions: The results of surgical treatment of peripheral nerves gunshot injury are generally worse than other types of nerve injuries. The best results of surgical treatment of combat trauma of peripheral nerves are obtained in patients with sciatic nerve damage.

Ecological comparative assessment of selected materials used for the construction of spark ignition engines

The aim of the article is to present the environmental effects of changes in material composition in selected internal combustion engines used in passenger cars using LCA analysis. The levels of energy consumption and emissions of pollutants related to material inputs occurring at the stage of engine production have been determined. The simplified LCA model presented in the paper shows the energy consumption and total CO2 and SO2 emissions on the basis of the mass of materials from which the engine is made. The research results presented in the paper give a picture of a modern passenger car engine on the basis of wear and the degree of recovery of materials used for its construction.

Low-cost procedure for deformity correction in rheumatoid hands

Background Surgical correction of ulnar drift of metacarpo-phalangeal joint (MPJ) due to Rheumatoid arthritis (RA) is conventionally done by silicon joint arthroplasty which is expensive and may be associated with many complications. We report the outcome of low-cost autologous interpositional arthroplasty. Material and methods Five patients (8 hands, 32 arthroplasties) underwent correction of ulnar drift of MPJ by dorsal capsule interpositional arthroplasty. Results were assessed according to the degree of recovery of movement at the MPJ and correction of ulnar drift. Functional improvement was graded as excellent, good and fair. Pain alleviation was assessed by visual analogue score (VAS) score. Results Excellent results were seen in 3 patients (5 hands, 20 arthroplasties), good in 1 patient (2 hands, 8 arthroplasties) and fair in 1 patient (1 hand, 4 arthroplasties). VAS score for pain decreased from mean preoperative 8.2/10 to 1/10. On average follow up of 1.4 years there was good hand function, no recurrence of deformities and patients were pain free. Conclusion Interpositional arthroplasty for MPJ using dorsal capsule for correction of post RA ulnar drift is a low-cost option which improves the hand function and cosmesis. Additionally, it avoids all the complications related with the use of silicon joints.

Reversal of Forest Soil Acidification in the Northeastern United States and Eastern Canada: Site and Soil Factors Contributing to Recovery

As acidic deposition has decreased across Eastern North America, forest soils at some sites are beginning to show reversal of soil acidification. However, the degree of recovery appears to vary and is not fully explained by deposition declines alone. To assess if other site and soil factors can help to explain degree of recovery from acid deposition, soil resampling chemistry data (8- to 24-year time interval) from 23 sites in the United States and Canada, located across 25° longitude from Eastern Maine to Western Ontario, were explored. Site and soil factors included recovery years, sulfate (SO42−) deposition history, SO42− reduction rate, C horizon pH and exchangeable calcium (Ca), O and B horizon pH, base saturation, and exchangeable Ca and aluminum (Al) at the time of the initial sampling. We found that O and B horizons that were initially acidified to a greater degree showed greater recovery and B horizon recovery was further associated with an increase in recovery years and lower initial SO42− deposition. Forest soils that seemingly have low buffering capacity and a reduced potential for recovery have the resilience to recover from the effects of previous high levels of acidic deposition. This suggests, that predictions of where forest soils acidification reversal will occur across the landscape should be refined to acknowledge the importance of upper soil profile horizon chemistry rather than the more traditional approach using only parent material characteristics.

STUDY OF THE ADSORPTION PROPERTIES OF PLANT CELLULOSE WITH RESPECT TO NICKEL IONS

In this paper, we studied the sorption properties of cellulose isolated from sugar beet pulp in relation to Ni2+. Plant cellulose from sugar beet pulp was isolated by successive acid and alkaline extraction, the effectiveness of which was evaluated by infrared spectroscopy. The sorption test showed that cellulose extracted from sugar beet pulp sorbed the main amount of Ni2+ within 1 hour. The maximum sorption capacity of cellulose from beet pulp pulp was 5.01 mmol Nh2+ per 1 kg of dry cellulose from pulp beet pulp. The amount of sorbed Ni2+ depended on the initial Ni2+ concentration in the solution. The most effective recovery of Ni2+ occurred from solutions with a Ni2+ concentration no more than 23.17 μmol/l, allowing to achieve a degree of recovery of this heavy metal of 67.9%. An increase in the initial concentration of Ni2+ in the solution resulted in a reduction in the degree of recovery of this element to 18.6%, which indicates the feasibility of using cellulose from sugar beet pulp for purification of water contaminated with nickel compounds in low concentrations. Comparison of the efficiency of Ni2+ sorption at different pH values showed that this process is pH dependent and the amount of sorbed Ni2+ and the degree of recovery of Ni2+ by cellulose from sugar beet pulp increased with increasing of pH values from 3.0 to 7.0.

Mechanical grinding of components of silicone manganese charge to improve the reproducibility

The present state of smelting of ferrosilicon manganese due to the deterioration of the quality of manganese concentrates is characterized by low extraction of manganese, silicon and an increase in the slag multiplicity. This requires the improvement of smelting technology with the use of charge materials with high reactivity, which is ensured by their preliminary preparation for melting.One method of preparation may be the method of mechanical activation of components separately or joint activation to provide high rates of the degree of recovery of elements in the metal phase.In order to attract mechanically activated fine materials for smelting of si-licomanganese, the basic technological requirements of preliminary preparation of briquetting briquette are grounded. Using hydrolysis lignin as a binder provides strong briquettes. At pressing pressures of 450-550 kg/cm2, the strength of the raw braces is 65-68 kg/cm2, and the fired in a reducing atmosphere at temperatures up to 1000оС, the strength reaches 160-185 kg/cm2.The study of the kinetics of joint carbon-thermal reduction of manganese and silicon at temperatures of 1250-1600 ° C with continuous weight loss control of the charge batch shows that the degree of recovery of the fractured, mechanically activated charge is 1.5 - 1.8 times higher than the reproducibility of the charge component 3- 0 mm and 2-3 times higher than the degree of recovery of the factory charge.Based on the results of chemical analysis of the experimental metal samples, it is shown that the application of mechanical activation in the joint processing of the mixture is significantly higher characteristics of extraction of manganese in the alloy by reducing the pre-formation of the slag phase and the recovery in this case of manganese from the slag melt