Technology development has blessed the business environment with many tremendous opportunities and created several challenges. One of these developments is mobile payment applications, which are inevitable in the modern word. Companies, customers, etc. are adopting this modern mobile application to avail the service of mobile payment. Without any doubt it has many advantages, but it has also many challenges in adoption. This chapter discusses the adoption of mobile application and its impact on business. Security, ease of use, service availability, and risk are some of the main factors contributing to the adoption of mobile payment application. These factors not only affect the adoption of MPA but also have a strong link with business. As MPA changes the mood of business, again its pros and cons exist, and there is a need to be addressed. This chapter concludes a proposed model for the adoption of mobile payment application after thorough literature review.