scholarly journals Length of hospital stay of COVID-19 patients and its relationship with liver function abnormalities

2021 ◽  
pp. 8-12
Author(s):  
Shishir Sikto Sarker ◽  
SM Ali Hasan ◽  
Md Sarower Islam ◽  
Nimai Das ◽  
Kazi Monisur Rahman ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Liver Function ◽  
Serum Albumin ◽  
Hospital Stay ◽  
Virus Disease ◽  
Length Of Hospital Stay ◽  
Global Public Health ◽  
Healthcare Resources ◽  
Corona Virus ◽  
Low Serum

Corona Virus Disease (COVID-19), a threat to global public health, caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) has now spread to more than two hundred countries in the world. This ongoing pandemic has already been exhausted our health care systems. So determining or predicting the need of healthcare resources has now become a number one priority and the length of hospitalization is a scale which represents the function of the health system of countries. Our objectives were to see the length of hospital stay of COVID-19 patients and its relationship with liver function abnormalities. This obser- vational cross-sectional study was carried out in the COVID-19 inpatient department of BSMMU on 96 patients who are RT-PCR positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Liver function abnormalities (ALT, AST, ALP, PT, serum biliru- bin and serum albumin) were recorded precisely. Length of hospital stay was documented. Occurrence of liver function abnormalities and their relation with length of hospital stay were assessed statistically. Total 96 patients were included. Mean hospital stay was found to be 14.0±6.2 with range from 5.0 to 33 days. Total 49(51.0%) patients required hospital staying ≤14 days and 47(49%) patients were found hospital stay > 14 days. Mean length of hospital stay in case of mild COVID-19 patients was 6.76±1.12 days, in case of moderate Covid-19 patients was 12.22±1.91 days and in severe group it was 19.18±4.81 days. The mean length of hospital stay was statistically significant with raised ALT (18.9±6.2), raised AST(18.9±5.9) and low serum albumin (19.4±7.1) group (p<0.05). No significant association was found between mean length of hospital stay and raised ALP, PT and S. bilirubin group. This study showed that length of hospital stay were significantly higher among severe COVID-19 patients and among liver function abnormalities raised ALT, raised AST and low serum albumin were associated with significant longer hospital stay. Assessing the length of hospital stay is helpful in under- standing and predicting hospital bed demand and optimizing the use of healthcare resources. BSMMU J 2021; 14 (COVID -19 Supplement): 8-12

Understanding the Dynamics of COVID-19 Outbreak: Structure, Diagnosis, Prevention and Treatment

2021 ◽  
Vol 19 ◽  
Author(s):  
Rohan R. Narkhede ◽  
Rameshwar S. Cheke ◽  
Sachin D. Shinde ◽  
Vitthal G. Kuchake ◽  
Nilesh M. Mahajan ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Viral Entry ◽  
Virus Disease ◽  
Clinical Information ◽  
Developed Countries ◽  
Acute Respiratory Tract Infection ◽  
World Health ◽  
Unknown Etiology ◽  
Global Public Health ◽  
Corona Virus

: Currently, mankind is fighting against an invisible enemy. The novel Corona virus disease (COVID-19) has been spreading at a rapid rate across the world, which made World health Organization (WHO) to declare it as a pandemic disease. COVID-19 is acute respiratory tract infection that was first reported in December 2019, initially presented as pneumonia of unknown etiology in a group of patients in Wuhan, a city in the Hubei Province of China. Sometimes corona virus from animals infect human and spread further via human to human transmission similar with the case of Middle East respiratory syndrome coronavirus (MERS-CoV), severe acute respiratory syndrome related coronavirus (SARS-CoV), and yet again with severe acute respiratory syndrome corona virus 2 (SARS-CoV-2), previously referred to as 2019-nCoV (COVID-19). SARS-CoV-2 is an extremely pathogenic virus and is crushing the health systems of well-equipped developed countries. According to WHO situation report updated on October 25, 2020 over 42 million cases and 1.1 million deaths have been reported globally. Since the figure of cases continues to increase, these viruses create a threat to global public health. This review summarizes an overview on the study of novel coronavirus including origin, epidemiology, etiology, targets for viral entry and describes the clinical manifestation, diagnosis, and therapeutics used in clinical settings. Furthermore, our review focuses on the most up-to-date clinical information for the effective management, prevention, and counseling provided to control COVID-19 worldwide.

Coronavirus and Fingerprint Technology

2021 ◽  
Vol 13 (4) ◽  
pp. 1-16
Author(s):  
Gabriel B. Iwasokun
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Viral Infection ◽  
Virus Disease ◽  
High Rate ◽  
Corona Virus ◽  
The World ◽  
Almost All

The corona virus disease, otherwise known as COVID-19, is an extremely communicable and pathogenic viral infection caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2), which emerged in Wuhan, China in December 2019 and has spread to almost all the countries in the world. The transmission of the virus is through touching of the nose, eyes, or mouth by a finger that has been contaminated through droplets on a surface when a carrier sneezes or coughs. Since the existing fingerprint devices are predominantly contact based, it implies that they can aid in the transmission of the virus. This paper discusses the application of fingerprint devices in notable places with high rate of COVID-19 infection as well as the threats to fingerprint technologies and the countermeasures. The need to change focus and orientation towards contactless biometric technologies as sure solution to the fear and animosity expressed towards contact-based fingerprint technology is also expatiated.

Inflammatory and nutritional markers as predictors of longer hospital stay and suboptimal residual disease (RD) in ovarian cancer (OVCA).

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. 5076-5076
Author(s):  
Michelle Torres ◽  
Lynn C. Hartmann ◽  
William Cliby ◽  
Kimberly Kalli ◽  
Aminah Jatoi ◽  
...  
Keyword(s):  
Neoadjuvant Chemotherapy ◽  
Serum Albumin ◽  
Hospital Stay ◽  
Inflammatory Markers ◽  
Residual Disease ◽  
Prognostic Score ◽  
Glasgow Prognostic Score ◽  
Stage Iv ◽  
Length Of Hospital Stay ◽  
Surgical Morbidity

5076 Background: Advanced OVCA should be managed aggressively, and extensive surgery has been the most accepted initial treatment. Medically unfit patients or those with extensive disease, in which complete cytoreduction is unlikely, may not benefit from upfront radical surgery, and neoadjuvant chemotherapy might be an appropriate alternative. Thus, reliable preoperative indicators of surgical outcome are necessary for considering primary surgery vs. neoadjuvant chemotherapy. Our aim is to determine if C-reactive protein (CRP), IL-6, albumin and Glasgow Prognostic Score (GPS – score based on CRP and albumin) correlate with overall survival (OS), length of hospital stay (LOS), surgical morbidity, and suboptimal cytoreduction. Methods: We randomly selected 50 stages III/IV OVCA who underwent surgery as a primary treatment between July 2002 and June 2009 at Mayo Clinic with serum albumin levels and frozen serum available. CRP and IL-6 were measured in stored serum. Univariate and multivariate regression models were fit to evaluate associations with each of the outcomes. Results: Among the 50 patients, the mean age was 67.7 years. 34% had pretreatment albumin <3.5 g/ml, 22.4% had CRP level ≥10 mg/l, 26.5% had IL-6 ≥24 pg/ml and 45% had abnormal GPS score. At 1, 3 and 5 years following surgery, the OS was 75.6%, 49.8% and 36.9%, respectively. RD (0, <1, ≥1cm; p<0.001) was the only independent predictor of OS. Also, IL-6 (p=0.028) and stage (p=0.046) were independently associated with LOS, but no inflammatory or nutritional markers were significant associated with post surgical complications. Stage IV (p=0.019) and elevated CRP (p=0.044) were independent predictors of suboptimal surgery (RD ≥ 1cm). Conclusions: One-third of the patients in our series had low serum albumin at the time of the OVCA diagnosis, and at least one-fourth had elevated inflammatory markers. Advanced stage and elevated inflammatory markers (CRP and IL-6) were independent predictors of longer hospital stay and suboptimal debulking. These pilot data, if confirmed in a larger population, may help in the selection of candidates for neoadjuvant chemotherapy.

scholarly journals IDOSOS DESCENDENTES DE UCRANIANOS DE UMA COMUNIDADE RURAL: SIGNIFICADOS CULTURAIS ATRIBUÍDOS À PANDEMIA DA COVID-19

2020 ◽  
Vol 17 (2) ◽  
Author(s):  
Fátima Denise Padilha Baran ◽  
Márcia Marrocos Aristides Barbiero ◽  
Patrícia Rosa Gonçalves Leta ◽  
Susanne Elero Betiolli ◽  
Karina t Silveira de Almeida Hammerschmid ◽  
...  
Keyword(s):  
Qualitative Research ◽  
Severe Acute Respiratory Syndrome ◽  
Virus Disease ◽  
Corona Virus

Introdução: a implementação de ações preventivas e de proteção foram preconizadas para reduzir o contágio Corona Vírus Disease-19 causado pelo vírus Severe Acute Respiratory Syndrome Coronavirus-2. Os idosos residentes em comunidades rurais demonstravam dificuldades em se adaptar às novas medidas. Objetivo: interpretar os significados culturais atribuídos à pandemia de idosos descendentes de ucranianos residentes em zona rural. Método: trata-se de pesquisa qualitativa descritiva sustentada pelos referenciais da antropologia cultural e conduzida pelo Consolidate criteria for reporting qualitative research. Participaram de entrevistas etnográficas nove idosos informantes chaves, por via Skype e chamadas de vídeo pelo whatsapp, no período de março a abril de 2020. As entrevistas foram analisadas segundo domínios culturais. Resultados: Emergiram três domínios: 1- “Providência divina que gerou mudanças” - os idosos atribuem à pandemia o desejo de Deus para gerar um aprendizado e mudança de vida; 2- “O cuidado que vem de Deus e do médico para consigo e com o outro”- eles revelam práticas cotidianas para evitar a contaminação, como fazer o que o médico diz, tomar coisas fortes como os antigos, acreditar em Deus, ficar longe das pessoas que não moram na mesma casa, não sair de casa e não receber visitas; e 3 - “Sentimentos desagradáveis que podem adoecer”- eles apontam como consequências sentimento de tristeza e solidão, dificuldades em aceitar as mudanças impostas, incerteza no futuro. Conclusão: os significados atribuídos à pandemia permearam a intensificação e preservação das crenças e práticas religiosas, e a proteção para a doença percorreu o saber médico e popular. 

scholarly journals AYURVEDIC APPROACH TO COVID-19

2021 ◽  
Vol 9 (6) ◽  
pp. 1223-1226
Author(s):  
Rachna Gupta ◽  
Amit Chowdhary
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Virus Disease ◽  
Clinical Settings ◽  
Evidence Based ◽  
Evidence Based Treatment ◽  
World Community ◽  
Corona Virus

Today the whole world community is facing an unprecedented pandemic of novel corona virus disease (COVID- 19) caused by Severe Acute Respiratory Syndrome Corona virus 2 (SARS-CoV- 2). The disease has spread glob- ally with more than 20.3 million confirmed cases and 2, 22000 deaths in India only as of May 4, 2021. Despite worldwide efforts, the pandemic is continuing to spread, and no system of medicine has any evidence-based treatment for COVID-19 as yet. The dimensions of pandemic require an urgent harnessing of all knowledge sys- tems available globally. Drawing attention on the Ayurveda classics, contemporary scientific studies, and experi- ential knowledge on similar clinical settings, depending on the stage of infection among individuals, in a popula- tion, Ayurveda system of medicine requires immediate implementation. It will facilitate learning, generate evi- dence and shall be a way forward. Keywords: COVID-19, Pandemic, SARS-CoV-2, Ayurveda, Immunity

scholarly journals INFECTION CONTROL IN DENTAL CLINICS DURING COVID 19 –Original Review

2020 ◽  
Author(s):  
Raunak Manjeet ◽  
KULDEEP D’MELLO ◽  
ATUL SINGH ◽  
SWATI SRIVASTAVA
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Infection Control ◽  
Virus Disease ◽  
Control Strategies ◽  
Dental Practice ◽  
Corona Virus ◽  
Management Protocol ◽  
Spread Pattern ◽  
Spread Of Infection ◽  
Aerosol Infection

The outbreak of severe acute respiratory syndrome corona virus 2 (SARS COV 2) and its linked corona virus disease has troubled the entire world community led to a serious public health concerns. Despite the various efforts to stop the spread of this disease globally, the outbreak is still on the rise because of the community spread pattern of this disease. This is believed to have originated in bats pangolins initially later it got transmitted to humans. Once it comes in the human body , this corona virus remains abundantly present in nasopharyngeal and salivary secretions of affected patients. Its spreading nature is mainly through the respiratory droplet spread / aerosol infection. Dental professionals, including Orthodontists , Oral Surgeons , Periodontists, Endodontists and Prosthodontists are all at high risk, since they may encounter patients with suspected or confirmed SARS COV 2 infection will have to act accordingly not only to provide care but at the same time prevent nosocomial spread of infection. Thus, the aim of this article is to provide a brief detailing of the cause, sign symptoms and different routes of transmission of this infection. In addition specific recommendations for dental practice are suggested for patient screening, infection control strategies and patient management protocol . KEY WORDS Coronavirus ,COVID 19, SARS COV 2 ,Dental practice ,Orthodontics ,OMFS, severe acute respiratory syndrome .

scholarly journals Public Health Education Pencegahan Penyebaran Covid-19 Dengan Disiplin Protokol Kesehatan Dan Melakukan Isolasi Mandiri Di Rumah

2021 ◽  
Vol 4 (4) ◽  
pp. 933-940
Author(s):  
Akhmad Kheru Dharmawan ◽  
Ibnu Aji Setyawan ◽  
Nia Triswanti ◽  
Hetti Rusmini ◽  
Ni Putu Sudiadnyani ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Social Life ◽  
Virus Disease ◽  
Public Health Education ◽  
Physical Contact ◽  
Group 13 ◽  
Social Community ◽  
Corona Virus ◽  
The Social ◽  
The Impact

ABSTRAK COVID-19 atau Corona Virus Diesease-19 adalah sebuah penyakit terbaru di tahun 2019 yang disebabkan oleh Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Covid-19 melanda banyak Negara di dunia termasuk Indonesia. Pandemi Covid-19 tidak hanya merupakan masalah nasional dalam suatu negara, tapi sudah merupakan masalah global. Covid-19 berawal dari daerah Wuhan Cina. Penyebaran Covid -19 yang begitu cepat dan beresiko kematian. Penularannya diduga melalui aerosol pada daerah mulut, mata dan hidung. Covid-19 berdampak kepada kehidupan sosial dan melemahnya ekonomi masyarakat yang kemudian mempengaruhi pelayanan publik. Permasalahan yang disoroti adalah bagaimana dampak pandemi Covid-19 terhadap pelayanan publik dan upaya penanggulangan wabah COVID-19.. Tujuan dari kegiatan ini adalah untuk meningkatkan pengetahuan tentang pentingnya melakukan isolasi mandiri untuk memutus rantai penyebaran COVID-19 di lingkungan masyarakat.  Metode yang digunakan dalam kegiatan ini yaitu penyuluhan kepada ibu-ibu kader di wilayah kerja Puskesmas Kedaton tentang pentingnya menjalani protokol kesehatan dan melakukan isolasi mandiri di rumah sebagai tindakan preventif untuk memutus rantai penyebaran COVID-19. Pelaksanaan kegiatan oleh mahasiswa FK Malahayati kelompok 13 CHOP dan pihak puskesmas kedaton dan dilaksanakan pada tanggal 19 Desember 2020. Hasil dari kegiatan ini adalah meningkatnya pengetahuan kader tentang pentingnya penerapan protokol kesehatan di masa pandemi COVID-19 ini sehingga penyuluhan ini berdampak baik dan efektif. Kata Kunci : Edukasi, Kesehatan, Covid  ABSTRACT COVID-19 or Corona Virus Disease 19 is a new illness in 2019 caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Covid-19 hit many countries in the world including Indonesia. The Covid-19 outbreak is not only a national problem in a country but already a global problem. Covid -19 originated in the Wuhan area of China. The spread of Covid-19 is so fast and deadly, transmission through physical contact is transmitted by the aerosol through the mouth, eyes, and nose. Covid-19 has an impact on social life and the weakening of the people's economy. The issue of how the impact of the Covid-19 outbreak on public services and efforts to overcome the Covid-19 outbreak. The Problem that followed is about how’s the impact of the outbreak affects public service. The purpose of this activity is to increase the knowledge about how too important it do self-isolation to cut off the transmission of COVID-19 in the social community. The method that used in this activity is counseling the cadres in the puskesmas kedaton her territory about how too important to do self-isolation to cut off the transmission of COVID-19 in the social community. The activity was assisted by the students of the medical faculty of Malahayati University especially group 13 CHOP and staff of puskesmas kedaton and was held on December 19, 2020. The results of this activity are increased knowledge of the cadres about how too important to do self-isolation to cut off the transmission of COVID-19 in the social community so that can be concluded this counseling worked so well and effectively. Keywords: Education, Health, Covid

scholarly journals Novel immunogenomic insights of corona virus disease (COVID-19): Available potential immunotherapeutics, current challenges, immune cell recognition and ongoing managerial strategies

2020 ◽  
Vol 7 (8) ◽  
pp. 3906-3915
Author(s):  
Kabeer Haneef ◽  
Muhammad Umer Asghar ◽  
Ashiq Ali
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Virus Strain ◽  
Immune Cell ◽  
Virus Disease ◽  
Adaptive Immune System ◽  
Antiviral Drugs ◽  
Corona Virus ◽  
Wide Range ◽  
Managerial Strategies ◽  
Spread Of Infection

The emerging Corona virus strain (severe acute respiratory syndrome corona virus-2 (SARS-CoV-2)) harbors intricate in the development of corona virus infection (COVID-19)-induced pneumonia and subsequently ameliorates lung infection. Genome sequence and interventions reveal proximal resemblance of corona virus strain COVID-19 with severe acute respiratory syndrome (SARS), transmittable to bats, suggesting similar primary hosts in the spread of infection. However, potential rapid human-to-human transmission has caused therapeutic challenges in treating a wide range of humans suffering from corona virus all over the world. However, up to now, no direct vaccines or antiviral drugs are available to treat COVID-19. Previously designed antiviral drugs and convalescent plasma are undergoing investigations as treatment for COVID-19 infected patients. Therapeutic challenges with regards to COVID-19 have prompted scientists to develop fruitful remedies to combat the pathogen. In this review, we address the role of current ongoing therapeutic strategies, , and complex mechanisms of adaptive immune system (B and T cells) to respond to viruses. Furthermore, we illustrate the current challenges in the treatment of COVID-19, managerial strategies, and ongoing and future perspectives.

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