scholarly journals Depression and Type 2 Diabetes Mellitus: A Call to Explore the Common Cause Hypothesis

2011 ◽  
Vol 171 (11) ◽  
pp. 1040 ◽  
Author(s):  
Briana Mezuk
2013 ◽  
Vol 16 (1) ◽  
pp. 91-102 ◽  
Author(s):  
Shmuel Levit ◽  
Yury Ivanovich Filippov ◽  
A S Gorelyshev

Diabetes mellitus is a heterogeneous group of diseases that, although unified by a number of characteristics, require a differential thera- peutic approach. Current review discusses key pathogenic features of type 2 diabetes mellitus that determine therapy goals and options in management. We further enunciate and pathogenetically substantiate a new "gravicentric" concept for treatment of type 2 diabetes mellitus that differs in many ways from the common contemporary approach.


2016 ◽  
Vol 02 ◽  
pp. 118
Author(s):  
M Vignesh ◽  
T Sangeetha ◽  
T Varsha ◽  
◽  
◽  
...  

Type 2 diabetes mellitus (T2DM) is one of the threatening disorders in the world. It affects people of all ages. Type 2 diabetes mellitus is a condition in which the glucose level in the blood is elevated due to improper function of the secretion of insulin from beta cells of the pancreas. It is a multifactorial disease because it is caused by both environmental and hereditary factors. One of the genes which play an important role in type 2 diabetes mellitus is SLC30A8 which encodes for zinc transporter ZnT8. The common polymorphic site for SLC30A8 is rs13266634. This single-nucleotide polymorphism leads to type 2 diabetes mellitus by replacing the arginine residue with tryptophan residue. This review mainly focuses on the polymorphic studies in the gene SLC30A8 and its association with type 2 diabetes mellitus.


Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 4150
Author(s):  
Carlos Jiménez-Cortegana ◽  
Pedro Iglesias ◽  
Josep Ribalta ◽  
Teresa Vilariño-García ◽  
Laura Montañez ◽  
...  

Cardiovascular disease (CVD) is the most common cause of morbidity and mortality in developed countries. The prevalence of CVD is much higher in patients with type 2 diabetes mellitus (T2DM), who may benefit from lifestyle changes, which include adapted diets. In this review, we provide the role of different groups of nutrients in patients with T2DM and CVD, as well as dietary approaches that have been associated with better and worse outcomes in those patients. Many different diets and supplements have proved to be beneficial in T2DM and CVD, but further studies, guidelines, and dietary recommendations are particularly required for patients with both diseases.


2011 ◽  
Vol 2011 ◽  
pp. 1-11 ◽  
Author(s):  
Grace Sun ◽  
Sangeeta R. Kashyap

Type 2 diabetes mellitus (DM2) is increasing in incidence, creating worldwide public health concerns and impacting morbidity and mortality rates. An increasing number of studies have demonstrated shared associations between DM2 and malignancy, including key clinical, biochemical, and metabolic commonalities. This paper will attempt to explore the relationship between the various types of cancer and diabetes, the common metabolic pathways underlying cancer development, and the potential impact of various antidiabetes therapies on cancer risk.


2020 ◽  
Vol 19 (2) ◽  
pp. 237-239
Author(s):  
Kartick Chanda Shaha ◽  
Md Shamsur Rahman ◽  
Tasmin Shahnaz ◽  
Habibunnahar

Objective: The aim of the present study was to find out the common co-morbid conditions associated with type 2 diabetes mellitus. Methods: A descriptive, cross sectional study was conducted from January 2016 to June 2016 among 300 patients attending at Medicine outpatient department of the Community Based Medical College Hospital and Endocrine outpatient department of the Mymensingh Medical College Hospital after obtaining requisite consent from the patients. Data were collected through the interviewing of the patients. The collected data were entered into the computer and analyzed by using SPSS (version 20.1) to know the common co-morbid conditions associated with type 2 diabetes mellitus. The study was approved by the institutional ethical committee. Results: In a pool of 300 type 2 diabetics, Most of the patients (57.3%) belonged to the middle age group 41-60 years. More than half of the respondents were female (n=223, 74.3%). Among 300 cases, 188 patients had shown association with different co-morbid conditions. Female patients (77%) suffered from more co-morbid conditions than male patients (23%). Hypertension was the most commonly associated disease (65.42%) with DM. Conclusion: Most of the diabetic patients have co-morbid conditions. Hypertension was the most commonly associated disease with DM. Bangladesh Journal of Medical Science Vol.19(2) 2020 p.237-239


Author(s):  
Atousa Najmaldin ◽  
Solmaz Askari ◽  
Majid Foroutan

Introduction: Studies have shown the association between subclinical hypothyroidism and type 2 diabetes. However, the common complications of type 2 diabetes, such as diabetic nephropathy and albuminuria with subclinical hypothyroidism, are not fully clear yet. This study thus aimed to determine the association between subclinical hypothyroidism and albuminuria in patients with type 2 diabetes mellitus. Methods: This was a cross-sectional study, of 140 individuals diagnosed with type 2 diabetes mellitus (DM) admitted to the internal clinics of Kosar Hospital in Semnan, Iran in 2017-2018. The participants were selected, and were compared based on having 2 TSH levels above normal (>4.2 mIU/L) 3 months apart, as well as patients were divided to two groups including, subclinical hypothyroidism group (n=40) and euthyroid group (n=100) based on demographic information, laboratory information and indicators such as albuminuria, and urinary albumin-to-creatinine ratio (UACR). Findings: The mean and standard deviation of UACR in patients with subclinical hypothyroidism were significantly higher than those of euthyroid patients (46.09 ± 27 9.27 vs. 3.94 ± 0.24 and P = 0.015, respectively). In patients with subclinical hypothyroidism, there was a statistically significant and direct relationship between UACR values with primary TSH level (r = 0.555, P< 0.001) and UACR values with secondary TSH level (r = 0.563, P< 0.001). Conclusion: Among type 2 DM patients, the rate of albuminuria in subclinical hypothyroidism group was significantly higher than that of euthyroid patients and with increasing initial and recurrent TSH levels, UACR values and consequently albuminuria increased.


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