Endophytes: Potential Source of Therapeutically Important Secondary Metabolites of Plant Origin

2017 ◽  
pp. 213-237 ◽  
Author(s):  
Shahid Iqbal Mohammed ◽  
Mohini Panditrao Patil ◽  
Ravindra Himmatrao Patil ◽  
Vijay Laxminarayan Maheshwari
Keyword(s):  
Secondary Metabolites ◽  
Plant Origin ◽  
Potential Source

Bioprospecting Cryptogams as Potential Source of Unique Biodynamic Phytochemicals with Diverse Pharmaceutical Applications

2016 ◽  
Vol 1 (1) ◽  
Author(s):  
Brahma N. Singh ◽  
Garima Pandey ◽  
Prateeksha ◽  
J. Kumar
Keyword(s):  
Secondary Metabolites ◽  
Higher Plants ◽  
New Drugs ◽  
Terrestrial Plants ◽  
Pharmacological Activities ◽  
Therapeutic Drugs ◽  
Potential Source ◽  
Therapeutic Value ◽  
Wide Range ◽  
Novel Structures

With the advent of green pharmaceuticals, the secondary metabolites derived from plants have provided numerous leads for the development of a wide range of therapeutic drugs; however the discovery of new drugs with novel structures has declined in the past few years. Cryptogams including lichens, bryophytes, and pteridophytes represent a group of small terrestrial plants that remain relatively untouched in the drug discovery process though some have been used as ethnomedicines by various tribes worldwide. Studies of their secondary metabolites are recent but reveal unique secondary metabolites which are not synthesized by higher plants. These compounds can have the potential to develop more potential herbal drugs for prevention and treatment of diseases The present article . deals with the secondary metabolites and pharmacological activities of cryptogams with an objective to bring them forth as potential source of biodynamic compounds of therapeutic value.

scholarly journals Actinomycetes as An Environmental Scrubber

2021 ◽  
Author(s):  
Sutaria Devanshi ◽  
Kamlesh R. Shah ◽  
Sudipti Arora ◽  
Sonika Saxena
Keyword(s):  
Secondary Metabolites ◽  
Agricultural Waste ◽  
Chemical Compounds ◽  
Filamentous Bacteria ◽  
Primary And Secondary Metabolites ◽  
Sustainable Environment ◽  
Potential Source ◽  
Wide Range ◽  
Bioactive Secondary Metabolites ◽  
Broad Variety

Biotechnological tools engaged in the bioremediation process are in reality, sophisticated and dynamic in character. For specialized reasons, a broad variety of such devices are employed to produce a safe and balanced environment free of all types of toxins and so make life simpler for humans on planet Earth. Actinomycetes is one of these extremely important and functionally helpful groups. They can be used for a variety of bioremediation objectives, including biotransformation, biodegradation, and many more. Actinomycetes are one of the most varied groups of filamentous bacteria, capable of prospering in a variety of ecological settings because to their bioactive capabilities. They’re famous for their metabolic diversity, which includes the synthesis of commercially useful primary and secondary metabolites. They produce a range of enzymes capable of totally destroying all of the constituents. They are well-known for their ability to produce bioactive secondary metabolites. Members of various genera of Actinomycetes show promise for application in the bioconversion of underutilized urban and agricultural waste into high-value chemical compounds. The most potential source is a wide range of important enzymes, some of which are synthesized on an industrial scale, but there are many more that have yet to be discovered. Bioremediation methods, which use naturally existing microbes to clear residues and contaminated regions of dangerous organic chemicals, are improving all the time. In the realm of biotechnological science, the potential of actinomycetes for bioremediation and the synthesis of secondary metabolites has opened up intriguing prospects for a sustainable environment.

scholarly journals Sesquiterpene lactones – occurrence and biological properties. A review

2018 ◽  
Vol 73 (3) ◽  
pp. 83-95
Author(s):  
KATARZYNA OLESIŃSKA
Keyword(s):  
Biological Activity ◽  
Secondary Metabolites ◽  
Plant Pathogens ◽  
Higher Plants ◽  
Sesquiterpene Lactones ◽  
Biological Properties ◽  
Chemical Structures ◽  
Potential Source ◽  
Active Substances ◽  
Carbon Pathways

Sesquiterpene lactones are secondary metabolites commonly found in higher plants as well as mosses, lichens, and fungi. Currently, over 5000 of such compounds have been identified with a majority isolated from Asteraceae plants. They are characterised by different chemical structures associated with the presence of various carbon pathways and functional groups, which exert an impact on their pharmacological activity. These colourless substances are soluble in fats, alcohols, or water. They are often bitter ingredients regarded as bitter compounds. They are accumulated mainly in leaves, flower parts and seeds; less frequently, they are present in roots. Sesquiterpene lactones exhibit multidirectional biological activity: some of them have anticancer, anti-inflammatory, antidiabetic, analgesic, antiparasitic, antifungal, and bacteriostatic effects. Therefore, high hopes are placed on the medical and pharmaceutical use of these substances. Lactone compounds are also regarded as a potential source of new active substances used in agriculture to combat plant pathogens

scholarly journals Therapeutic Potential of Kalanchoe Species: Flavonoids and other Secondary Metabolites

2008 ◽  
Vol 3 (12) ◽  
pp. 1934578X0800301 ◽  
Author(s):  
Sônia S. Costa ◽  
Michelle F. Muzitano ◽  
Luiza M. M. Camargo ◽  
Marcela A. S. Coutinho
Keyword(s):  
Secondary Metabolites ◽  
Traditional Medicine ◽  
Bioactive Compounds ◽  
Therapeutic Potential ◽  
Point Of View ◽  
Present Review ◽  
Biological Profile ◽  
Research Programs ◽  
Potential Source ◽  
The World

The Kalanchoe genus (syn. Bryophyllum), family Crassulaceae, comprises 125 species, most of them native to Madagascar. The great importance of several of these species for the traditional medicine in several regions of the World, esspecially India, Africa, China and Brazil, stimulated research programs into these plants from both a pharmacological and chemical point of view. The present review focuses on the main results obtained during the last decade on the secondary metabolites isolated from these species – endowed or not with a specific biological profile – with emphasis on flavonoids. The distribution of these molecules in the genus will be summarized and special attention will be given to K. brasiliensis and K. pinnata, two species well-known for healing inflammatory and infectious processes. Ornamental Kalanchoe species are also discussed as a potential source of bioactive compounds. This review covers the period 1970–2008.

Can Ocimum basilicum L. and Ocimum tenuiflorum L. in vitro culture be a potential source of secondary metabolites?

2016 ◽  
Vol 194 ◽  
pp. 55-60 ◽  
Author(s):  
Karuppiah Bhuvaneshwari ◽  
Ananda Gokulanathan ◽  
Malayandi Jayanthi ◽  
Vaithiyanathan Govindasamy ◽  
Luigi Milella ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
In Vitro Culture ◽  
Ocimum Basilicum ◽  
Potential Source ◽  
Ocimum Tenuiflorum

scholarly journals Tropical biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry?

Química Nova ◽  
2012 ◽  
Vol 35 (11) ◽  
pp. 2278-2287 ◽  
Author(s):  
Marilia Valli ◽  
Marcos Pivatto ◽  
Amanda Danuello ◽  
Ian Castro-Gamboa ◽  
Dulce Helena Siqueira Silva ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Medicinal Chemistry ◽  
Tropical Biodiversity ◽  
Potential Source

Biologically active secondary metabolites from Actinomycetes

2012 ◽  
Vol 7 (3) ◽  
pp. 373-390 ◽  
Author(s):  
Jolanta Solecka ◽  
Joanna Zajko ◽  
Magdalena Postek ◽  
Aleksandra Rajnisz
Keyword(s):  
Biological Activity ◽  
Secondary Metabolites ◽  
Chemical Structure ◽  
Multidrug Resistant ◽  
Biologically Active ◽  
Plant Roots ◽  
Bacterial Strains ◽  
Genus Streptomyces ◽  
Gram Negative ◽  
Potential Source

AbstractSecondary metabolites obtained from Actinomycetales provide a potential source of many novel compounds with antibacterial, antitumour, antifungal, antiviral, antiparasitic and other properties. The majority of these compounds are widely used as medicines for combating multidrug-resistant Gram-positive and Gram-negative bacterial strains. Members of the genus Streptomyces are profile producers of previously-known secondary metabolites. Actinomycetes have been isolated from terrestrial soils, from the rhizospheres of plant roots, and recently from marine sediments. This review demonstrates the diversity of secondary metabolites produced by actinomycete strains with respect to their chemical structure, biological activity and origin. On the basis of this diversity, this review concludes that the discovery of new bioactive compounds will continue to pose a great challenge for scientists.

scholarly journals Phytochemistry and Diverse Pharmacology of Genus Mimosa: A Review

Biomolecules ◽  
2022 ◽  
Vol 12 (1) ◽  
pp. 83
Author(s):  
Komal Rizwan ◽  
Ismat Majeed ◽  
Muhammad Bilal ◽  
Tahir Rasheed ◽  
Ahmad Shakeel ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Skin Diseases ◽  
Cytotoxic Activities ◽  
Fatty Esters ◽  
Potential Source ◽  
Small Pox ◽  
Pharmacological Studies ◽  
Ornamental Trees ◽  
The Tropics ◽  
Near Future

The genus Mimosa belongs to the Fabaceae family and comprises almost 400 species of herbs, shrubs and ornamental trees. The genus Mimosa is found all over the tropics and subtropics of Asia, Africa, South America, North America and Australia. Traditionally, this genus has been popular for the treatment of jaundice, diarrhea, fever, toothache, wound healing, asthma, leprosy, vaginal and urinary complaints, skin diseases, piles, gastrointestinal disorders, small pox, hepatitis, tumor, HIV, ulcers and ringworm. The review covered literature available from 1959 to 2020 collected from books, scientific journals and electronic searches, such as Science Direct, Web of Science and Google scholar. Various keywords, such as Mimosa, secondary metabolites, medicines, phytochemicals and pharmacological values, were used for the data search. The Mimosa species are acknowledged to be an essential source of secondary metabolites with a wide-ranging biological functions, and up until now, 145 compounds have been isolated from this genus. Pharmacological studies showed that isolated compounds possess significant potential, such as antiprotozoal, antimicrobial, antiviral, antioxidant, and antiproliferative as well as cytotoxic activities. Alkaloids, chalcones, flavonoids, indoles, terpenes, terpenoids, saponins, steroids, amino acids, glycosides, flavanols, phenols, lignoids, polysaccharides, lignins, salts and fatty esters have been isolated from this genus. This review focused on the medicinal aspects of the Mimosa species and may provide a comprehensive understanding of the prospective of this genus as a foundation of medicine, supplement and nourishment. The plants of this genus could be a potential source of medicines in the near future.

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