Nanophytomedicine: An Effective Way for Improving Drug Delivery and Bioavailability of Herbal Medicines

2020 ◽  
pp. 55-70
Author(s):  
Mohammad Zaidur Rahman Sabuj ◽  
Nazrul Islam
Keyword(s):  
Drug Delivery ◽  
Herbal Medicines

Nanomaterials for the delivery of Herbal Bioactive Compounds

2021 ◽  
Vol 17 ◽  
Author(s):  
Shadma Wahab ◽  
Md. Parwez Ahmad ◽  
Arshad Hussain ◽  
Shaik Fayazuddin Abdul Qadir
Keyword(s):  
Drug Delivery ◽  
Bioactive Compounds ◽  
Targeted Drug Delivery ◽  
Herbal Medicines ◽  
Herbal Drugs ◽  
Herbal Extracts ◽  
Significant Component ◽  
Pharmaceutical Application ◽  
Low Solubility ◽  
Insight Into

: Nanotechnology is a multidisciplinary domain that involves overlapping of areas such as nonanomaterials, nanoelectronics, and nanobiotechnology. Herbal medicine is a significant component of traditional medicine and has been a treatment part of many diseases. Asian peoples are using these herbal medicines for decades. Still, herbal extracts' therapeutic efficacy and pharmaceutical application are associated with many factors such as poor bioavailability, low solubility, permeability, and lack of targeting potential. In the present work, we have reviewed thriving strategies for the targeted drug delivery of phytoconstituents and critically explain the most recent progressions on emerging novel nanophytomedicine-based materials as herbal medicines carriers. Nanotechnology-based clinical trial studies targeting herbal bioactive compounds were discussed. Advancements in nanotechnology-based drug delivery systems intended to enhance cellular uptake, improved pharmacokinetics and effectiveness of herbal drugs have facilitated the powerful targeting of specific agents against diseases. This review provides insight into current progress and future opportunities for nanomedicines as potential curative targets for the delivery of herbal bioactive compounds. This information could be used as platforms for the future expansion of multi-functional nano constructs for the advanced detection of diseases and functional drug delivery of phytoconstituents.

Herbal Liposomes: Natural Network for Targeted Drug Delivery System

2021 ◽  
pp. 31-41
Author(s):  
Vijay R. Salunkhe ◽  
Prasanna S. Patil ◽  
Ganesh H. Wadkar ◽  
Somnath D. Bhinge
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Targeted Drug Delivery ◽  
Therapeutic Potential ◽  
Herbal Medicines ◽  
Lipid Solubility ◽  
Liposomal Formulations ◽  
Novel Drug ◽  
Herbal Formulations

Herbal medicines have tremendous therapeutic potential that can explored across various effective drug delivery system. Decoctions, herbal teas, tinctures, glyceritum, oxymel, and use much soap, herbal tablets, herbal capsules, and herbal cream, herbal books, and prepared the confection of the most commonly available forms of dosage. The less use of herbal formulations in recent decades due to their lack of standardization. It is possible to use plant extract and isolated constituents to overcome this problem. But these phytoconstituents are suffering from drawbacks, mostly due to problems with stability and low lipid solubility. Novel drug delivery such as liposomes plays an important role in problem solving. Infact, compliance with the patient also improves. The review article discusses the recent status of new herbal liposomal formulations and describes the different ways in which these formulations are prepared.

scholarly journals Formulation and Characterization of Cefixime Phytosomes for Oral Drug Delivery

1970 ◽  
Vol 7 (5) ◽  
pp. 65-73
Author(s):  
Saloni Jain ◽  
Rahul Ancheriya ◽  
S Srivastva ◽  
Shankar Lal Soni ◽  
Mukesh Sharma
Keyword(s):  
Drug Delivery ◽  
Oral Drug Delivery ◽  
Biological Activities ◽  
Herbal Medicines ◽  
Memory Loss ◽  
Oral Drug ◽  
Target Tissue ◽  
Drug Bioavailability ◽  
Age Related ◽  
Health Promoting

Novel drug delivery systems (NDDS) are one of the most strategies which enable to overcome the problems related to drug bioavailability. It is the rate and extent to which a drug becomes available to the target tissue after its administration. Over the last century, phyto-chemical science and phyto-pharmacological science established numerous plant compounds with various biological activities and health promoting benefits such as anti-mutagenicity, anti-carcinogenicity and anti-oxidative activity, for age-related diseases namely memory loss, osteoporosis, diabetic wounds, immune and liver disorders, etc. Herbal medicines have been known since eons for their safety, efficacy, folk acceptability and fewer side effects.  

scholarly journals Herbal Nanogel Formulation: A Novel Approch

2020 ◽  
pp. 138-146
Keyword(s):  
Drug Delivery ◽  
Patient Compliance ◽  
Drug Delivery Systems ◽  
Polymer Networks ◽  
Herbal Medicines ◽  
Future Generation ◽  
Herbal Drugs ◽  
High Drug ◽  
Sustained Drug Delivery ◽  
Novel Approach

:Increasing research interest has been focused on controlled as well as sustained drug delivery using natural and biocompatible constituents in recent years. Many of them herbal constituents are avoided due to pharmacokinetic and pharmacodynamic issues of herbal constituents. There are many new technological ways and comparisons have been studied to upgrade the herbal discoveries in pharmaceutical market. This review will focus on the nanogel for herbal medicines with high delivery rate, patient compliance and efficiency. A nanoparticles contained hydrogel with cross linked polymer networks called as ‘Nanogel’. Nanogel preferred for herbal medicines due to stability and for the ease. Nanogels in terms of herbal drugs are promising and novel approach which also can be called as future generation drug delivery systems owing to high drug encapsulation capacity, uniformity, minimum toxicity, greater stability.

Therapeutic Efficacy of Herbal Formulations Through Novel Drug Delivery Systems

2021 ◽  
pp. 1-42
Author(s):  
Arvind Kumar Singh Chandel ◽  
Nutan Bhingradiya
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Herbal Medicines ◽  
Bioactive Compound ◽  
Delivery Systems ◽  
Bioactive Molecules ◽  
Therapeutic Molecules ◽  
Dose Accuracy ◽  
The Many ◽  
Novel Drug

The herbal-based drugs have been getting wide attention over the last few decades. The herbal drugs have been used from the ancient times, but the dose accuracy, efficacy, and treatment was just based on symptomatic observatory. Modern research is focused on pure bioactive compound instead of crude. The researchers are trying to apply the current advanced nanotechnology-based knowledge on the herbal medicines to improve efficacy and reduces the unwanted pharmacological actions' adverse effects of the therapeutic molecules. The many novel drug delivery systems available used for the herbal bioactive molecules include polymeric micelle, injectable hydrogel, nano gel, nano emulsions, microsphere, polymeric nanoparticles, nano capsules, liposomes, phytosomes, transferosomes, dendrimer, and ethosomes. This chapter highlights the existing research and development of current standing of the of various novel formulations especially for the herbal bioactive molecules and summarizes their active ingredients, commercial formulations, route of drug administration, and pharmacological activity.

Herbal Medicines in Neurodegenerative Disorders: An Evolutionary Approach through Novel Drug Delivery System

2018 ◽  
Vol 37 (3) ◽  
pp. 199-208 ◽  
Author(s):  
Sunil Kumar Dubey ◽  
Gautam Singhvi ◽  
Kowthavarapu Venkata Krishna ◽  
Tejas Agnihotri ◽  
Ranendra Narayan Saha ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Neurodegenerative Disorders ◽  
Herbal Medicines ◽  
Evolutionary Approach ◽  
Novel Drug Delivery System ◽  
Novel Drug

scholarly journals Nanotechnology-based drug delivery systems and herbal medicines: a review

2013 ◽  
pp. 1 ◽  
Author(s):  
Patrícia Silva ◽  
Bruna Bonifácio ◽  
Matheus Ramos ◽  
Kamila Negri ◽  
Tais Maria Bauab ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Herbal Medicines ◽  
Delivery Systems

Current Trends in Phyto-cancer Therapy Using Nanoparticles

2019 ◽  
Vol 9 (1) ◽  
pp. 30-45 ◽  
Author(s):  
K. Vohra ◽  
H. Dureja ◽  
V. Garg ◽  
R. Dutt
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Loading ◽  
Herbal Medicines ◽  
High Efficacy ◽  
Global Challenge ◽  
Alternative Medicines ◽  
Current Trends ◽  
Low Toxicity ◽  
Novel Drug

Background:Cancer has been considered as a deadly disease and its appropriate management is still a global challenge. The traditional anticancer therapeutics have been able to combat the disease to some extent but with numerous adverse effects which affect the quality of life of patients.Method:The introduction of alternative medicines, especially herbal medicines, has attracted the scientists’ due to low toxicity and high efficacy associated with them. However, their poor solubility and bioavailability decrease their efficacy. This has led to the increased use of targeted drug delivery systems in phyto-cancer therapy.Results:Nanoparticles (NPs), a novel drug delivery system has been widely used in the recent years due to their various advantages such as drug targeting, improved solubility, and bioavailability, high efficacy, low toxicity towards normal cells, low drug resistance, high drug loading at tumor site, etc.Conclusion:These benefits have also been observed in studies evaluating phytonanotherapy in cancer. The present review highlights current trends followed by phyto-cancer therapy using NPs. The recent studies conducted on herbal NPs for cancer therapy have also been enlisted.

scholarly journals Challenges, Advances and Opportunities of Herbal Medicines in Wound Healing: A Review

2021 ◽  
Vol 71 (1) ◽  
Author(s):  
Balap A.R ◽  
Gaikwad A.A
Keyword(s):  
Drug Delivery ◽  
Wound Healing ◽  
Drug Delivery System ◽  
Delivery System ◽  
Herbal Medicines ◽  
Herbal Remedies ◽  
Wound Management ◽  
Wide Range ◽  
Healing Wound ◽  
Herbal Formulations

A large portion of the world's population relies on herbs for medical purposes today. About 25-30% of modern drugs are chemical intermediates derived from plant constituents. Traditional medicinal plant preparations are frequently utilised for wound healing, encompassing a wide range of skin-related disorders. In wound management, herbal medicine entails cleaning, debridement, and the creation of an environment that promotes natural healing. This review discusses wound, healing of the wound, allopathic treatment in wound healing, types of herbal medicines used in the treatment of wound healing and common excipients used in topical herbal formulations. In this article, we look at 15 plants that have been utilised as wound healers in traditional medicine around the world. This study is an attempt to search the difficulties and challenges of herbal formulations need for novel drug delivery system nanocarriers for herbal remedies with other nanotechnology strategies and techniques as a new drug delivery system and its future prospective. The purpose of this review is to examine the most common excipients used in herbal formulations, as well as various medicinal plants traditionally used in wound healing, wound healing difficulties and challenges, the use of nanotechnology in herbal formulation, the future scope of herbal medicines in wound healing, and a comparison of allopathy and herbal formulations.

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