Smoking and coffee intake following alcohol withdrawal in alcoholic inpatients

SummaryThe aim of this study was to assess alcoholic inpatients' smoking and coffee intake variation following withdrawal. Only moderate smokers (less than 30 cigarettes/day) showed a significant increase of cigarette consumption after alcohol withdrawal. However, their urinary cotinine level did not vary, suggesting a behavioral, and not biological, compensation through smoking following alcohol withdrawal. Heavy smokers (30 cigarettes/day or more) showed no significant clinical or biological variation of smoking behavior. Coffee consumption increased after alcohol withdrawal in all patients, irrespective of smoking habits.

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Cigarette smoking increases coffee consumption: findings from a Mendelian randomisation analysis

10.1101/107037 ◽

2017 ◽

Author(s):

Johan H Bjørngaard ◽

Ask Tybjærg Nordestgaard ◽

Amy E Taylor ◽

Jorien L Treur ◽

Maiken E. Gabrielsen ◽

...

Keyword(s):

Causal Effect ◽

Coffee Consumption ◽

Cigarette Consumption ◽

Mendelian Randomisation ◽

Caffeine Intake ◽

Tea Consumption ◽

Coffee Intake ◽

General Population Study ◽

Weak Evidence ◽

The Uk

AbstractBackgroundSmokers tend to consume more coffee than non-smokers and there is evidence for a positive relationship between cigarette and coffee consumption in smokers. Cigarette smoke increases the metabolism of caffeine, so this association may represent a causal effect of smoking on caffeine intake.MethodsWe performed a Mendelian randomisation analysis in 114,029 individuals from the UK Biobank, 56,664 from the Norwegian HUNT study and 78,650 from the Copenhagen General Population Study. We used a genetic variant in the CHRNA5 nicotinic receptor (rs16969968) as a proxy for smoking heaviness. Coffee and tea consumption were self-reported. Analyses were conducted using linear regression and meta-analysed across studies.ResultsEach additional cigarette per day consumed by current smokers was associated with higher coffee consumption (0.10 cups per day, 95% CI:0.03,0.17). There was weak evidence for an increase in tea consumption per additional cigarette smoked per day (0.04 cups per day, 95% CI:-0.002,0.07). There was strong evidence that each additional copy of the minor allele of rs16969968 (which increases daily cigarette consumption) in current smokers was associated with higher coffee consumption (0.15 cups per day, 95% CI:0.11,0.20), but only weak evidence for an association with tea consumption (0.04 cups per day, 95% CI:- 0.01,0.09). There was no clear evidence that rs16969968 was associated with coffee or tea consumption in never or former smokers.ConclusionThese findings suggest that higher cigarette consumption causally increases coffee intake. This is consistent with faster metabolism of caffeine by smokers, but may also reflect behavioural links between smoking and coffee.

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Smoking Habits of Smoking Researchers: Missionaries or Hypocrites?

Psychological Reports ◽

10.2466/pr0.1974.35.3.1085 ◽

1974 ◽

Vol 35 (3) ◽

pp. 1085-1086 ◽

Cited By ~ 1

Author(s):

Stephen B. Levenberg ◽

Robert V. Heckel ◽

Mervyn K. Wagner

Keyword(s):

Comparison Group ◽

Smoking Behavior ◽

Cigarette Consumption ◽

Smoking Habits ◽

National Rate

A survey of the smoking behavior of researchers who produce literature related to smoking was conducted. This group's current rate of cigarette consumption did not differ from the national rate or that of a comparison group of researchers, but differences were found in the current rate of cigar and pipe smoking and in the speed with which producers of smoking research are ceasing the habit.

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FAKTOR – FAKTOR YANG BERHUBUNGAN DENGAN KEJADIAN PNEUMONIA PADA BALITA DI WILAYAH KERJA PUSKESMAS WONOREJO SAMARINDA TAHUN 2017

KESMAS UWIGAMA: Jurnal Kesehatan Masyarakat ◽

10.24903/kujkm.v3i2.338 ◽

2018 ◽

Vol 3 (2) ◽

pp. 76

Author(s):

Novi Anggun Pusvitasary

Keyword(s):

Environmental Factors ◽

Family Member ◽

Cause Of Death ◽

Family Members ◽

Smoking Behavior ◽

Smoking Habits ◽

P Value ◽

Behavioral Factors ◽

The World ◽

Health Standards

Pneumonia disease is the leading cause of death of babies in the world. The prevalence of pneumonia in infants is 18.5 / mil. Data from Samarinda City Health Office during the last 1 year there are 91 cases of pneumonia in Karang Anyar Village and 63 cases in Teluk Lerong Ulu Village. Factors causing pneumonia are toddler factors, behavioral factors, and environmental factors. The results show there is a relationship between house humidity (p value = 0,013; OR = 0,192), house dwelling density (p value = 0,024; OR = 0,214), and family member smoking behavior (p value = 0,006; OR = 10,450) with incidence of pneumonia in toddlers in the Working Area of Puskesmas Wonorejo Samarinda. There was no correlation between house temperature (p value = 0,214; OR = 0,337), house lighting (p value = 0,095; OR = 3,188) and family disease history (p value = 0,707; OR = 0,753) with Pneumonia occurrence in infant in region Work Puskesmas Wonorejo Samarinda. It was concluded that there was a relationship between house humidity, home dwelling density, and smoking behavior of family members with the incidence of pneumonia in infants. It is recommended to be able to apply housing health requirements that meet health standards to reduce the incidence of pneumonia in infants and change smoking habits.

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Coffee consumption and risk of renal cell carcinoma in the NIH-AARP Diet and Health Study

International Journal of Epidemiology ◽

10.1093/ije/dyab011 ◽

2021 ◽

Author(s):

Jongeun Rhee ◽

Erikka Loftfield ◽

Neal D Freedman ◽

Linda M Liao ◽

Rashmi Sinha ◽

...

Keyword(s):

Renal Cell Carcinoma ◽

Cell Carcinoma ◽

Renal Cell ◽

Cox Regression ◽

Coffee Consumption ◽

Health Study ◽

Coffee Intake ◽

Decaffeinated Coffee ◽

Incident Cases ◽

Reduced Risk

Abstract Background Coffee consumption has been associated with a reduced risk of some cancers, but the evidence for renal cell carcinoma (RCC) is inconclusive. We investigated the relationship between coffee and RCC within a large cohort. Methods Coffee intake was assessed at baseline in the National Institutes of Health–American Association of Retired Persons Diet and Health Study. Among 420 118 participants eligible for analysis, 2674 incident cases were identified. We fitted Cox-regression models to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for coffee consumption vs non-drinkers. Results We observed HRs of 0.94 (95% CI 0.81, 1.09), 0.94 (0.81, 1.09), 0.80 (0.70, 0.92) and 0.77 (0.66, 0.90) for usual coffee intake of <1, 1, 2–3 and ≥4 cups/day, respectively (Ptrend = 0.00003). This relationship was observed among never-smokers (≥4 cups/day: HR 0.62, 95% CI 0.46, 0.83; Ptrend = 0.000003) but not ever-smokers (HR 0.85, 95% CI 0.70, 1.05; Ptrend = 0.35; Pinteraction = 0.0009) and remained in analyses restricted to cases diagnosed >10 years after baseline (HR 0.65, 95% CI 0.51, 0.82; Ptrend = 0.0005). Associations were similar between subgroups who drank predominately caffeinated or decaffeinated coffee (Pinteraction = 0.74). Conclusion In this investigation of coffee and RCC, to our knowledge the largest to date, we observed a 20% reduced risk for intake of ≥2 cups/day vs not drinking. Our findings add RCC to the growing list of cancers for which coffee consumption may be protective.

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The Effect of Green Coffee Consumption on High Blood Pressure

Critical Comments in Biomedicine ◽

10.18502/ccb.v2i1.5869 ◽

2021 ◽

Author(s):

Mahdieh Hosseinzadeh ◽

Fatemeh Pakravanfar ◽

Elham Hosseinzadeh ◽

Maryam Khosravi

Keyword(s):

Blood Pressure ◽

Clinical Trials ◽

High Blood Pressure ◽

Coffee Consumption ◽

Vascular Diseases ◽

Publication Date ◽

Green Coffee ◽

Chlorogenic Acids ◽

Coffee Intake ◽

Randomized Controlled Clinical Trials

Background: Hypertension is a major risk factor for the development of coronary, cerebrovascular, and peripheral vascular diseases, which lead to myocardial infarction, stroke, and vascular death. Green coffee extract is particularly producer a great deal of chlorogenic acids (CGA) that may reduce the risk of high blood pressure. Therefore, the target of the study was to summarize the available publications on the effect of green coffee consumption on high blood pressure. Methods: The systematic review was done with a search in PubMed-Medline and Scopus. The search strategy included keywords related to blood pressure and green coffee. Inclusion criteria were randomized controlled clinical trials conducted on people aged between 18 and 70 years. The publication date of articles was from 2004 to 2018. Exclusion criteria were articles not published in English. Results: We discussed five articles that included our criteria. Green coffee had moderate effects on high blood pressure. It sounds that the effect of green coffee on reducing blood pressure is because of its phenolic compounds, as well as caffeine and chlorogenic acids, coffee’s roasting status, participants’ ethnicity, and even gender. Conclusion: Green coffee intake for a long time might moderately decrease blood pressure. However, there is still a need for further clinical trials.

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Metabolomic signatures of long-term coffee consumption and risk of type 2 diabetes in women

10.2337/figshare.12675611.v1 ◽

2020 ◽

Author(s):

Dong Hang ◽

Oana A. Zeleznik ◽

Xiaosheng He ◽

Marta Guasch-Ferre ◽

Xia Jiang ◽

...

Keyword(s):

Type 2 Diabetes ◽

Coffee Consumption ◽

Diabetes Risk ◽

Health Study ◽

Plasma Metabolites ◽

Case Control Studies ◽

Coffee Intake ◽

Decaffeinated Coffee ◽

Prediction Of Diabetes

Objective: Coffee may protect against multiple chronic diseases, particularly type 2 diabetes, but the mechanisms remain unclear. Research Design and Methods: Leveraging dietary and metabolomic data in two large cohorts of women (the Nurses’ Health Study I and II), we identified and validated plasma metabolites associated with coffee intake in 1595 women. We then evaluated the prospective association of coffee-related metabolites with diabetes risk and the added predictivity of these metabolites for diabetes in two nested case-control studies (n=457 cases and 1371 controls). Results: Of 461 metabolites, 34 were identified and validated to be associated with total coffee intake, including 13 positive associations (primarily trigonelline, polyphenol metabolites, and caffeine metabolites) and 21 inverse associations (primarily triacylglycerols and diacylglycerols). These associations were generally consistent for caffeinated and decaffeinated coffee, except for caffeine and its metabolites that were only associated with caffeinated coffee intake. The three cholesteryl esters positively associated with coffee intake showed inverse associations with diabetes risk, whereas the 12 metabolites negatively associated with coffee (five diacylglycerols and seven triacylglycerols) showed positive associations with diabetes. Adding the 15 diabetes-associated metabolites to classical risk factors-based prediction model increased the C-statistic from 0.79 (95% CI: 0.76, 0.83) to 0.83 (95% CI: 0.80, 0.86) (P<0.001). Similar improvement was observed in the validation set. Conclusion: Coffee consumption is associated with widespread metabolic changes, among which lipid metabolites may be critical for the anti- diabetes benefit of coffee. Coffee-related metabolites might help improve prediction of diabetes, but further validation studies <a>are </a>needed.

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Hubungan antara Kebiasaan Merokok dengan Angka Kejadian Lesi yang Diduga Stomatitis Nikotina pada Masyarakat Desa Ongkaw Dua

e-CliniC ◽

10.35790/ecl.7.2.2019.23979 ◽

2019 ◽

Vol 7 (2) ◽

Author(s):

Miranda A. Tambunan ◽

Pieter L. Suling ◽

Christy N. Mintjelungan

Keyword(s):

Significant Relationship ◽

Analytical Study ◽

Smoking Habit ◽

Smoking Habits ◽

P Value ◽

Chi Square ◽

Cross Sectional ◽

Cross Sectional Design ◽

The Relationship ◽

Heavy Smokers

Abstract: Nicotine stomatitis could be found among heavy smokers. This study was aimed to determine the relationship between smoking habits and the incidence of lesions suspected as nicotine stomatitis among villagers of Ongkaw Dua. This was an analytical study with a cross sectional design. Population consisted of 183 smokers aged >15 years at Desa Ongkaw Dua and the subjects were 65 smokers. The chi-square showed a p-value of 0.592 for the relationship between the duration of smoking and the occurence of lesion supspected as nicotine stomatitis. Moreover, the chi-square showed a p-value of 0.005 for the relationship between the number of cigarettes consumed per day and the occurence of lesion suspected as nicotine stomatitis. In conclusion, there was no relationship between the duration of smoking and the occurence of lesion suspected as nicotine stomatitis, but there was a significant relationship between the number of cigarettes consumed per day and the occurence of lesion suspected as nicotine stomatitis.Keywords: smoking habit, nicotine stomatitis Abstrak: Stomatitis nikotina dapat dijumpai pada perokok berat. Penelitian ini bertujuan untuk mengetahui hubungan antara kebiasaan merokok dengan angka kejadian lesi yang diduga stomatitis nikotina pada masyarakat desa Ongkaw Dua. Jenis penelitian ialah analitik observasional dengan desain potong lintang. Populasi penelitian ini yaitu 183 perokok berusia >15 tahun di Desa Ongkaw Dua dan yang menjadi subyek penelitian berjumlah 65 orang. Hasil uji chi-square terhadap hubungan lama merokok dengan angka kejadian lesi yang diduga stomatitis nikotina mendapatkan p=0,592. Hasil uji chi-square terhadap hubungan antara jumlah rokok yang dihisap setiap hari dengan angka kejadian lesi yang diduga stomatitis nikotina mendapatkan p=0,005. Simpulan penelitian ini ialah tidak terdapat hubungan antara lamanya merokok dengan angka kejadian lesi yang diduga stomatitis nikotina, tetapi terdapat hubungan bermakna antara jumlah rokok yang dihisap setiap hari dengan angka kejadian lesi yang diduga stomatitis nikotina.Kata kunci: kebiasaan merokok, stomatitis nikotina

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Assessment of the sublingual microcirculation with the GlycoCheck system: Reproducibility and examination conditions

PLoS ONE ◽

10.1371/journal.pone.0243737 ◽

2020 ◽

Vol 15 (12) ◽

pp. e0243737

Author(s):

Mie Klessen Eickhoff ◽

Signe Abitz Winther ◽

Tine Willum Hansen ◽

Lars Jorge Diaz ◽

Frederik Persson ◽

...

Keyword(s):

Intraclass Correlation ◽

Coffee Consumption ◽

Boundary Region ◽

Microvascular Perfusion ◽

Controlled Study ◽

Coffee Intake ◽

Sublingual Microcirculation ◽

Randomised Controlled Study ◽

Multiple Measurements ◽

Randomised Controlled

Background The glycocalyx is an extracellular layer lining the lumen of the vascular endothelium, protecting the endothelium from shear stress and atherosclerosis and contributes to coagulation, immune response and microvascular perfusion. The GlycoCheck system estimates glycocalyx’ thickness in vessels under the tongue from perfused boundary region (PBR) and microvascular perfusion (red blood cell (RBC) filling) via a camera and dedicated software. Objectives Evaluating reproducibility and influence of examination conditions on measurements with the GlycoCheck system. Methods Open, randomised, controlled study including 42 healthy smokers investigating day-to-day, side-of-tongue, inter-investigator variance, intraclass-correlation (ICC) and influence of examination conditions at intervals from 0–180 minutes on PBR and RBC filling. Results Mean (SD) age was 24.9 (6.1) years, 52% were male. There was no significant intra- or inter-investigator variation for PBR or RBC filling nor for PBR for side-of-tongue. A small day-to-day variance was found for PBR (0.012μm, p = 0.007) and RBC filling (0.003%, p = 0.005) and side-of-tongue, RBC filling (0.025%, p = 0.009). ICC was modest but highly improved by increasing measurements. Small significant influence of cigarette smoking (from 40–180 minutes), high calorie meal intake and coffee consumption was found. The latter two peaking immediately and tapering off but remained significant up to 180 minutes, highest PBR changes for the three being 0.042μm (p<0.05), 0.183μm (p<0.001) and 0.160μm (p<0.05) respectively. Conclusions Measurements with the GlycoCheck system have a moderate reproducibility, but highly increases with multiple measurements and a small day-to-day variability. Smoking, meal and coffee intake had effects up to 180 minutes, abstinence is recommended at least 180 minutes before GlycoCheck measurements. Future studies should standardise conditions during measurements.

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Abstract 021: C-reactive Protein Partially Mediates The Inverse Association Between Coffee Consumption And Risk Of Type 2 Diabetes: Findings From The UK Biobank And The Rotterdam Studies

Circulation ◽

10.1161/circ.143.suppl_1.021 ◽

2021 ◽

Vol 143 (Suppl_1) ◽

Author(s):

Carolina Ochoa-Rosales ◽

Niels van der Schaft ◽

Kim V Braun ◽

Frederick Ho ◽

Fanny Petermann ◽

...

Keyword(s):

Type 2 Diabetes ◽

Coffee Consumption ◽

Inverse Association ◽

Statistical Regression ◽

Uk Biobank ◽

C Reactive Protein ◽

Coffee Intake ◽

Reactive Protein ◽

The Uk

Background: Coffee intake has been linked to lower type 2 diabetes (T2D) risk. We hypothesized this may be mediated by coffee’s effects on inflammation. Methods: Using participants from the UK Biobank (UKB n=145370) and Rotterdam Study (RS n=7172) cohorts, we studied associations of coffee intake with incident T2D; longitudinally measured insulin resistance (HOMA IR); serum levels of inflammation markers; and the mediating role of inflammation. Statistical regression models were adjusted for sociodemographic, lifestyle and health factors. Results: The median follow up was 7 (UKB) and 9 (RS) years. An increase of one coffee cup/day was associated with 4-6% lower T2D risk (RS HR=0.94 [95% CI 0.90; 0.98]; UKB HR=0.96 [0.94; 0.98]); lower HOMA IR (RS β=-0.017 [-0.024; -0.010]); with lower C reactive protein (CRP) and higher adiponectin (Figure1). Consumers of filtered coffee had the lowest T2D risk (UKB HR=0.88 [0.83; 0.93]). CRP levels mediated 9.6% (UKB) and 3.4% (RS) of the total effect of coffee on T2D (Figure 1). Conclusions: We suggest that coffee’s beneficial effects on lower T2D risk are partially mediated by improvements in systemic inflammation.Figure 1. a CRP and a adiponectin refer to the effect of coffee intake on CRP and adiponectin levels. a CRP RS : β=-0.014 (-0.022; -0.005); UKBB a CRP UKB : β=-0.011 (-0.012; -0.009) and RS a adiponectin : β=0.025 (0.007; 0.042). b CRP and b adiponectin refer to the effect of coffee related levels in CRP and adiponectin on incident T2D, independent of coffee. RS b CRP : HR=1.17 (1.04; 1.31); UKB b CRP : HR=1.45 (1.37; 1.54); and b adiponectin : HR=0.58 (0.32; 0.83). c′ refers to coffee’ effect on T2D going directly or via others mediators. UKB c′ independent of CRP : HR=0.96 (0.94; 0.99); RS c′ independent of CRP : HR=0.94 (0.90; 0.99); and RS c′ independent of CRP+adiponectin : HR=0.90 (0.80; 1.01). Coffee related changes in CRP may partially explain the beneficial link between coffee and T2D, mediating a 3.4% (0.6; 4.8, RS) and 9.6% (5.7; 24.4, UKB). Evidence of mediation was also found for adiponectin.

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