Beyond stillbirth: association of IHCP and other adverse outcomes based on severity of disease

2022 ◽  
Vol 226 (1) ◽  
pp. S20-S21
Author(s):  
Minhazur R. Sarker ◽  
Andres Ramirez-Zamudio ◽  
Chelsea A. DeBolt ◽  
Lauren Ferrara
Keyword(s):  
Adverse Outcomes ◽  
Severity Of Disease

Comparison of Severity of Symptoms and Outcome among Vaccinated and Non-Vaccinated Covid 19 Patients in Khyber Pakhtunkhwa, Pakistan

2021 ◽  
Vol 15 (7) ◽  
pp. 2334-2337
Author(s):  
Wali Gul ◽  
Kashif Ali Samin ◽  
Rashid Ahmad ◽  
Khalil Ullah ◽  
Gul Mehnaz ◽  
...  
Keyword(s):  
Economic Status ◽  
Adverse Outcomes ◽  
Medicine Department ◽  
Khyber Pakhtunkhwa ◽  
Icu Admission ◽  
Severity Of Disease ◽  
Group I ◽  
Group Ii ◽  
Severity Of The Disease ◽  
Retrospective Comparative Study

Objective: The aim of this study is to compare the severity of symptoms and outcomes among vaccinated and non-vaccinated COVID 19 patients in Khyber Pakhtunkhwa, Pakistan Study Design: A Retrospective/ Comparative study Place and Duration: The study was conducted at Medicine department of Lady Reading Hospital, Peshawar and DHQ Category A Hospital, Batkhela for duration of six months between December 2020 and May 2021. Methods: Total 170 patients of both genders had coronavirus disease were presented in this study. Patients were aged between 20-80 years. Demographical details of patients including age, sex, body mass index, residency and socio-economic status were recorded after taking informed written consent. Patients were admitted in COVID 19 ward. There were 70 vaccinated patients in group I and 100 non-vaccinated patients in group II. Co-morbidities among both groups were assessed. Effectiveness and outcomes among both groups were calculated in terms of mortality and reduction in severity of disease. Complete data was analyzed by SPSS 19.0 version. Results: There were 114 (67.1%) patients were males (50 in group I and 64 in group II) and 56 (32.4%) were females (28 in each group). Mean age of the vaccinated patients was 49.16 ±8.55 years with mean BMI 33.16 ±4.64 kg/m2 and in group II mean age was 47.18 ±4.77 years with mean BMI 31.12±12.73 kg/m2.Among 70 cases of group I, 40 (57.1%) were fully vaccinated and 30 (42.9%) patients received their first dose. 50 (71.4%) were educated in group I and in group II 46 (46%) patients were literate. Co-morbidities were diabetes mellitus, hypertension, ischaemic heart and chronic lung disease. Effectiveness among patients of group I was greater 55 (78.6%) as compared to non-vaccinated 36 (36%). Frequency of adverse outcomes hospitalization 10 (10%), ICU admission 14 (14%) and mortality 40 (40%) among non-vaccinated patients were significantly higher as compared to vaccinated patients in which hospitalization 3 (4.3%), ICU admission 2 (2.9%) and mortality was found in 10 (14.3%) cases. Conclusion: We concluded in this study that vaccination against coronavirus disease was effective and helpful for the reduction in severity of the disease. Except this the frequency of adverse outcomes (hospitalization, ICU admission and mortality) can be minimized by vaccination and there is need to give awareness among people to get vaccinated early. Keywords: COVID 19, Vaccination, Pandemic, Mortality

Research Consumerism 101: Evaluating External Evidence of Treatment Effectiveness

2008 ◽  
Vol 17 (2) ◽  
pp. 43-49
Author(s):  
James L. Coyle
Keyword(s):  
Treatment Effectiveness ◽  
Code Of Ethics ◽  
Oropharyngeal Dysphagia ◽  
Clinical Importance ◽  
Professional Services ◽  
Adverse Outcomes ◽  
Professional Judgment ◽  
Evidence Based ◽  
Intervention Selection ◽  
Published Research

Abstract The modern clinician is a research consumer. Rehabilitation of oropharyngeal impairments, and prevention of the adverse outcomes of dysphagia, requires the clinician to select interventions for which evidence of a reasonable likelihood of a successful, important outcome exists. The purpose of this paper is to provide strategies for evaluation of published research regarding treatment of oropharyngeal dysphagia. This article utilizes tutorial and examples to inform and educate practitioners in methods of appraising published research. It provides and encourages the use of methods of efficiently evaluating the validity and clinical importance of published research. Additionally, it discusses the importance of the ethical obligation we, as practitioners, have to use evidence-based treatment selection methods and measurement of patient performance during therapy. The reader is provided with tactics for evaluating treatment studies to establish a study's validity and, thereby, objectively select interventions. The importance of avoiding subjective or unsubstantiated claims and using objective methods of generating empirical clinical evidence is emphasized. The ability to evaluate the quality of research provides clinicians with objective intervention selection as an important, essential component of evidence-based clinical practice. ASHA Code of Ethics (2003): Principle I, Rule F: “Individuals shall fully inform the persons they serve of the nature and possible effects of services rendered and products dispensed…” (p. 2) Principle I, Rule G: “Individuals shall evaluate the effectiveness of services rendered and of products dispensed and shall provide services or dispense products only when benefit can reasonably be expected.” (p. 2) Principle IV, Rule G: “Individuals shall not provide professional services without exercising independent professional judgment, regardless of referral source or prescription.” (p. 4)

SOOTY MOULD DISEASES OF SOME TREES FROM AURANGABAD DISTRICT, MAHARASHTRA (INDIA)

2017 ◽  
Vol 23 (2) ◽  
Author(s):  
NAVALSINGH J. TODAWAT
Keyword(s):  
Surface Area ◽  
Fungal Pathogens ◽  
Leaf Surface ◽  
Severity Of Disease ◽  
Sooty Mould ◽  
Leaf Surface Area

Sooty mould diseases of Tress from Aurangabad district were surveyed. During the survey of tress, 5 species were found infected by fungal pathogens causing sooty mould diseases. Disease is easily identifiable by the presence of a black, velvety growth covering the leaf surface area. The fungus produces mycelium which is superficial and dark grows on the flowers, leaf, stem and sometime on fruits also. The severity of disease depends on the honeydew secretions by insects. The diseases were found to be caused by 5 species of fungi viz. Capnodium anonae, C. ramosum, Capnodium sp., Meliola bangalorensis and Meliola ranganthii.

Early Outcomes of Coronary Endarterectomy in Patients Undergoing Coronary Artery Bypass Surgery

2016 ◽  
Vol 19 (2) ◽  
pp. 059
Author(s):  
Amin Bagheri ◽  
Ahmad Masoumi ◽  
Jamshid Bagheri
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass ◽  
Coronary Artery Bypass Surgery ◽  
Bypass Surgery ◽  
Artery Bypass ◽  
Adverse Outcomes ◽  
Supraventricular Arrhythmia ◽  
Coronary Endarterectomy ◽  
Early Results ◽  
The Impact

<strong>Background:</strong> Coronary endarterectomy (CE) is performed as an adjunct to coronary artery bypass surgery (CABG); however, the efficacy of this technique is still controversial. We aimed to evaluate the impact of CE combined with CABG when compared with isolated CABG.<br /><strong>Methods:</strong> Patients who underwent CABG between July 2007 and June 2014 were included. 70 of 2452 patients (2.8%) underwent CE in addition to CABG. Early results were compared with isolated CABG and predictors of adverse outcome were measured in stepwise multivariate logistic regression analyses.<br /><strong>Results:</strong> The incidence of comorbidities including prior myocardial infarction, diabetes mellitus, and three-vessel coronary disease in CE patients was higher; however, mortality (4.3% versus control 3.6%; P = .762) and postoperative complications were not significantly increased in this group of patients (except supraventricular arrhythmia). Although age greater than 70 years, impaired ejection fraction, intraoperative intraaortic balloon pump, and prolonged cardiopulmonary bypass time were important predictors of adverse outcomes, CE was not associated with increased mortality or postoperative morbidities. <br /><strong>Conclusion:</strong> Despite the higher risk profile of patients who underwent CE, this technique was not identified as an independent risk factor for adverse postoperative outcomes.

Advanced Management Options for Massive and Submassive Pulmonary Embolism

2016 ◽  
Vol 10 (1) ◽  
pp. 30 ◽  
Author(s):  
Sonika Malik ◽  
◽  
Anju Bhardwaj ◽  
Matthew Eisen ◽  
Sanjay Gandhi ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Vena Cava ◽  
Right Ventricular Dysfunction ◽  
Hemodynamic Instability ◽  
Adverse Outcomes ◽  
Intermediate Risk ◽  
Management Options ◽  
Vena Cava Filters ◽  
Submassive Pulmonary Embolism ◽  
Risk Patients

Pulmonary embolism (PE) is an important cause of morbidity and mortality and presents with significant diagnostic and therapeutic challenges. Clinical presentation ranges from mild, nonspecific symptoms to syncope, shock, and sudden death. Patients with hemodynamic instability and/ or signs of right ventricular dysfunction are at high risk for adverse outcomes and may benefit from aggressive therapy and support. Therapeutic anticoagulation is indicated in all patients in the absence of contraindications. Thrombolysis should be strongly considered in selected high- and intermediate-risk patients, either by systemic infusion or percutaneous catheter-directed therapy. Other therapeutic modalities, such as vena cava filters and surgical embolectomy, are options for patients who fail or cannot tolerate anticoagulation and/or thrombolysis. This article reviews the assessment and advanced management options for acute PE with focus on high- and intermediate-risk patients.

Relative risk of cardiovascular disease is higher in women with type 2 diabetes, but not in those with prediabetes, as compared with men

2020 ◽  
Author(s):  
Elena Succurro ◽  
Teresa Vanessa Fiorentino ◽  
Sofia Miceli ◽  
Maria Perticone ◽  
Angela Sciacqua ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Cardiovascular Disease ◽  
Longitudinal Study ◽  
Relative Risk ◽  
Hdl Cholesterol ◽  
Cross Sectional Study ◽  
Adverse Outcomes ◽  
Cross Sectional ◽  
Normal Glucose

<b>Objective</b>: Most, but not all studies suggested that women with type 2 diabetes have higher relative risk (RR) for cardiovascular disease (CVD) than men. More uncertainty exists on whether the RR for CVD is higher in prediabetic women compared to men. <p><b>Research Design and Methods</b>: In a cross-sectional study, in 3540 normal glucose tolerant (NGT), prediabetic, and diabetic adults, we compared the RR for prevalent non-fatal CVD between men and women. In a longitudinal study including 1658 NGT, prediabetic, and diabetic adults, we compared the RR for incident major adverse outcomes, including all-cause death, coronary heart disease, and cerebrovascular disease events after 5.6 years follow-up. </p> <p><b>Results:</b> Women with prediabetes and diabetes exhibited greater relative differences in BMI, waist circumference, blood pressure, total, LDL and HDL cholesterol, triglycerides, fasting glucose, hsCRP, and white blood cell count than men with prediabetes and diabetes when compared with their NGT counterparts. We found a higher RR for prevalent CVD in diabetic women (RR 9.29; 95% CI 4.73-18.25; <i>P</i><0.0001) than in men (RR 4.56; 95% CI 3.07-6.77; <i>P</i><0.0001), but no difference in RR for CVD was observed comparing prediabetic women and men. In the longitudinal study, we found that diabetic, but not prediabetic women have higher RR (RR 5.25; 95% CI 3.22-8.56; <i>P</i><0.0001) of incident major adverse outcomes than their male counterparts (RR 2.72; 95% CI 1.81-4.08; <i>P</i><0.0001).</p> <p><b>Conclusions:</b> This study suggests that diabetic, but not prediabetic, women have higher RR for prevalent and incident major adverse outcomes than men. </p>

Sign in / Sign up

Export Citation Format

Share Document