Comparative studies on the impact of synthesis methods on structural, optical, magnetic and catalytic properties of CuFe2O4

The review discusses the interchangeability of medications, approaches to the registration of original and generic drugs, and types of their equivalence, as well as problems with generics in clinical practice. Results of pharmacoepidemiological studies, which have been widely carried out recently, speak of insufficient understanding of the impact of generics on remote outcomes of chronic diseases, including mortality. The longterm economic prospects of generic drug administration continue to remain unclear. Among the primary differences between generics and brandname drugs are the differences in active ingredient synthesis methods and the composition of adjuvants and additives. Comparative studies on the therapeutic equivalence of generics with their originals or between themselves are rarely conducted. They are often affected by methodological flaws, which cannot ensure their comparable efficacy and safety. In this regard, automatic replacement of drugs containing the same active ingredient should be avoided without the participation of the attending physician.

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Aquatic Toxicity of Photocatalyst Nanoparticles to Green Microalgae Chlorella vulgaris

Water ◽

10.3390/w13010077 ◽

2020 ◽

Vol 13 (1) ◽

pp. 77

Author(s):

Cristina Adochite ◽

Luminita Andronic

Keyword(s):

Chlorella Vulgaris ◽

Advanced Oxidation Process ◽

Growth Parameters ◽

Aquatic Toxicity ◽

Basal Medium ◽

Inhibitory Effect ◽

Synthesis Methods ◽

Potent Inhibitory Effect ◽

Density Surface ◽

The Impact

In the last years, nanoparticles such as TiO2, ZnO, NiO, CuO and Fe2O3 were mainly used in wastewater applications. In addition to the positive aspects concerning using nanoparticles in the advanced oxidation process of wastewater containing pollutants, the impact of these nanoparticles on the environment must also be investigated. The toxicity of nanoparticles is generally investigated by the nanomaterials’ effect on green algae, especially on Chlorella vulgaris. In this review, several aspects are reviewed: the Chlorella vulgaris culture monitoring and growth parameters, the effect of different nanoparticles on Chlorella vulgaris, the toxicity of photocatalyst nanoparticles, and the mechanism of photocatalyst during oxidative stress on the photosynthetic mechanism of Chlorella vulgaris. The Bold basal medium (BBM) is generally recognized as an excellent standard cultivation medium for Chlorella vulgaris in the known environmental conditions such as temperature in the range 20–30 °C and light intensity of around 150 μE·m2·s−1 under a 16/8 h light/dark cycle. The nanoparticles synthesis methods influence the particle size, morphology, density, surface area to generate growth inhibition and further algal deaths at the nanoparticle-dependent concentration. Moreover, the results revealed that nanoparticles caused a more potent inhibitory effect on microalgal growth and severely disrupted algal cells’ membranes.

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RADT-37. THE IMPACT OF POSTOPERATIVE RADIATION THERAPY (PORT) AND EXTENT OF SURGERY ON CLINICAL OUTCOMES OF ATYPICAL MENINGIOMA (AM): A META-ANALYSIS

Neuro-Oncology ◽

10.1093/neuonc/noaa215.790 ◽

2020 ◽

Vol 22 (Supplement_2) ◽

pp. ii189-ii189

Author(s):

Philip Haddad ◽

Furqan Akhtar ◽

Kevin Gallagher

Keyword(s):

Clinical Outcomes ◽

Comparative Studies ◽

English Language ◽

Randomized Clinical Trials ◽

Meta Analysis ◽

Subtotal Resection ◽

Recurrence Rates ◽

Postoperative Radiation Therapy ◽

Extent Of Surgery ◽

The Impact

Abstract BACKGROUND Although meningiomas are among the most prevalent types of brain tumors, AMs account for around 4% of all meningiomas. AMs tend to be more aggressive with relatively higher rates of recurrence and mortality. Gross total resection (GTR) has been the standard of care when possible. However, GTR itself is not always enough to prevent the recurrence of AMs. The role of PORT remains controversial in AM as the comparative studies to support its use have provided conflicting RESULTS: The purpose of this meta-analysis is to evaluate the impact of PORT on clinical outcomes according to the extent of resection in AMs. METHODS A review of the medical literature was conducted using online databases. Inclusion criteria consisted of AM diagnosis, English language, Simpson graded resections, and comparative studies reporting recurrence rates (RcR), Progression-Free Survival (PFS), and Overall Survival (OS) with hazard ratios (HR) or Kaplan-Meier curves. A meta-analysis was conducted using an inverse variance method with a random-effects model. RESULTS Twenty-two comparative studies with a total of 5,129 patients were included and analyzed. When GTR was attained, PORT was associated with improved RcR (HR =0.72, 95%CI:0.59-0.86) and PFS (HR=0.77, 95%CI:0.65-0.90), but not OS (HR=0.93, 95%CI:0.83-1.04). When subtotal resection (STR) was attained, PORT was associated with improved PFS (HR=0.35, 95%CI:0.26-0.48) as well as OS (HR=0.70, 95%CI:0.54-0.89). The extent of surgery also impacted AM outcomes as GTR demonstrated superior PFS (HR=0.45, 95%CI:0.31-0.65) and OS (HR=0.30, 95%CI:0.13-0.72). CONCLUSIONS This is the first meta-analysis to show that PORT is associated with PFS benefit in AMs with GTR and STR. Moreover, PORT significantly improved OS of AMs that underwent STR but had no impact on OS when GTR was achieved. In the absence of randomized clinical trials, this meta-analysis represents the most compelling data supporting the use of PORT in this patient population.

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Research on Teaching the Psychology of Women

Psychology of Women Quarterly ◽

10.1111/j.1471-6402.1982.tb00612.x ◽

1982 ◽

Vol 7 (1) ◽

pp. 96-106 ◽

Cited By ~ 12

Author(s):

Marilyn Johnson

Keyword(s):

Comparative Studies ◽

Attitudes Toward Women ◽

Behavioral Measures ◽

Quantitative Studies ◽

Psychology Of Women ◽

Research On Teaching ◽

Follow Up Studies ◽

The Impact ◽

Review Current

Research into the impact of psychology of women courses (and women's studies, generally) has been conducted only infrequently. The literature consists largely of anecdotal reports of changes in attitudes toward women as a function of participating in such courses. Existing quantitative studies are usually limited to measures of pre-course to post-course attitude changes, and occasionally such changes are related to demographic factors. The purpose of this article is to review current studies and to suggest additional research approaches in this area. At least three methods are recommended for studying the effect of psychology of women courses. First, there is a need for comparative studies of two types: psychology of women course vs. other course comparisons, and psychology of women course vs. other related experiences (consciousness-raising groups, feminist therapy, etc.). Second, there is a need for follow-up assessment of students in these courses. Finally, in both the comparative and follow-up studies, behavioral measures should be used.

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PROBLEMS OF THE DEVELOPMENT OF PEASANT ECONOMIES AND FARMS IN THE MINDS OF THE LAND REFORM IN UKRAINE

THEORETICAL AND APPLIED ISSUES OF ECONOMICS ◽

10.17721/tppe.2019.38.10 ◽

2019 ◽

pp. 113-125

Author(s):

Olena Pimenova

Keyword(s):

Land Reform ◽

Agricultural Land ◽

Graphical Method ◽

Historical Analysis ◽

State Regulation ◽

Synthesis Methods ◽

Expert Evaluation ◽

Farm Model ◽

Analysis And Synthesis ◽

The Impact

The historical analysis of the development of national forms of economy has been carried out. It has been determined that the most economically advantageous for society, vital, rational, socio-ecological-economic forms of economy are peasant economies and farms. The methodological basis of the study as to the identification of rational and effective forms of economy are general scientific methods, including methods of historical analysis, generalization, comparison, analysis and synthesis, methods of expert evaluation, graphical method. In the course of the research, the methods of historical analysis, generalization, analysis and synthesis were used in carrying out a retrospective analysis, in particular the research of scientific opinion on the effectiveness of such forms of economy as peasants and farms and the impact of land reform on their development; the method of expert evaluation in the survey of peasants and representatives from the administration of Radomyshl region of Zhytomyr oblast to determine their opinion – how the land reform will affect on the development of peasants and farms; graphical method for constructing tables and graphs. The study of the world experience in agriculture confirmed that the development of the farm model as a priority model of economy in agriculture is possible only with the active support of a state, as an institution that regulates land use through administrative and economic measures and provides legislation through limitation of purchase of land and the potential withdrawal of this land from agricultural circulation, and also involves the implementation of targeted programs through the financing of individual activity. An important function of state regulation is the conservation of the agricultural land fund. In developed countries, there are some restrictions on the land market to prevent latifundia. It is substantiated that in the course of land reform, the agrarian policy should be focused on preventing the creation of latifundia with large land tenure, as well as on the support, protection and development of peasant economies and farms as viable forms.

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Survival Rates of Dental Implants in Autogenous and Allogeneic Bone Blocks: A Systematic Review

Medicina ◽

10.3390/medicina57121388 ◽

2021 ◽

Vol 57 (12) ◽

pp. 1388

Author(s):

Phil Donkiewicz ◽

Korbinian Benz ◽

Anita Kloss-Brandstädter ◽

Jochen Jackowski

Keyword(s):

Comparative Studies ◽

Survival Rates ◽

Risk Of Bias ◽

Autogenous Bone ◽

Cochrane Central Register ◽

Allogeneic Bone ◽

Level Of Evidence ◽

Low Level ◽

Significant Difference ◽

The Impact

Background and Objectives: Preliminary studies emphasize the similar performance of autogenous bone blocks (AUBBs) and allogeneic bone blocks (ALBBs) in pre-implant surgery; however, most of these studies include limited subjects or hold a low level of evidence. The purpose of this review is to test the hypothesis of indifferent implant survival rates (ISRs) in AUBB and ALBB and determine the impact of various material-, surgery- and patient-related confounders and predictors. Materials and Methods: The national library of medicine (MEDLINE), Excerpta Medica database (EMBASE) and Cochrane Central Register of Controlled Trials (CENTRAL) were screened for studies reporting the ISRs of implants placed in AUBB and ALBB with ≥10 participants followed for ≥12 months from January 1995 to November 2021. The review was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The risk of bias was assessed via several scoring tools, dependent on the study design. Means of sub-entities were presented as violin plots. Results: An electronic data search resulted in the identification of 9233 articles, of which 100 were included in the quantitative analysis. No significant difference (p = 0.54) was found between the ISR of AUBB (96.23 ± 5.27%; range: 75% to 100%; 2195 subjects, 6861 implants) and that of ALBB (97.66 ± 2.68%; range: 90.1% to 100%; 1202 subjects, 3434 implants). The ISR in AUBB was increased in blocks from intraoral as compared to extraoral donor sites (p = 0.0003), partially edentulous as compared to totally edentulous (p = 0.0002), as well as in patients younger than 45 as compared to those older (p = 0.044), cortical as compared to cortico-cancellous blocks (p = 0.005) and in delayed implantations within three months as compared to immediate implantations (p = 0.018). The ISR of ALBB was significantly increased in processed as compared to fresh-frozen ALBB (p = 0.004), but also in horizontal as compared to vertical augmentations (p = 0.009). Conclusions: The present findings widely emphasize the feasibility of achieving similar ISRs with AUBB and ALBB applied for pre-implant bone grafting. ISRs were negatively affected in sub-entities linked to more extensive augmentation procedures such as bone donor site and dentition status. The inclusion and pooling of literature with a low level of evidence, the absence of randomized controlled clinical trials (RCTs) comparing AUBB and ALBB and the limited count of comparative studies with short follow-ups increases the risk of bias and complicates data interpretation. Consequently, further long-term comparative studies are needed.

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Impact of globalization on the development of social entrepreneurship in Latvia

SHS Web of Conferences ◽

10.1051/shsconf/202112908008 ◽

2021 ◽

Vol 129 ◽

pp. 08008

Author(s):

Silva Jeromanova-Maura ◽

Rosita Zvirgzdina

Keyword(s):

Social Entrepreneurship ◽

Local Governments ◽

Quantitative Methods ◽

Negative Attitude ◽

Social Enterprises ◽

Added Value ◽

Synthesis Methods ◽

Eu Member States ◽

The Law ◽

The Impact

Research background: Since April 1, 2018, the Law on Social Entrepreneurship has been in force in Latvia. Unfortunately, the relatively slow preparation and adoption of the law did not bring any benefits to social enterprises (Jeromanova-Maura et al., 2019). Few social enterprises have recently been set up, operating in a small number of business sectors. Various financial support instruments are available to social enterprises, which could promote the establishment of a social enterprise, but the negative attitude of society and understanding of people with special needs is an obstacle to the establishment of new social enterprises. It is in the interests of local governments to give more support to social entrepreneurship in their region. The aim of the article: to study and analyze the processes that have contributed to the faster development of social entrepreneurship and the impact of globalization on the development of social entrepreneurship in Latvia during the last couple of years. To achieve this, the authors have studied the experiences of different countries in the development of social entrepreneurship, focusing on the EU Member States and how globalization has affected the development of social entrepreneurship in each country. Methods: The study uses methods of analysis and synthesis, methods of deduction and induction, as well as methods of logical approach. However, appropriate quantitative methods are used to process the data obtained. Findings & Added Value: The paper aims to assess the impact of globalization on social entrepreneurship as well as the impact of Covid on the creation and development of social enterprises.

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Economic impact of organised crime to state security

Problems of Legality ◽

10.21564/2414-990x.149.201728 ◽

2020 ◽

pp. 185-199

Author(s):

Aurelija Pūraitė

Keyword(s):

Organized Crime ◽

Secondary Analysis ◽

Organised Crime ◽

Synthesis Methods ◽

Secondary Sources ◽

State Security ◽

National Organizations ◽

The One ◽

Group Structures ◽

The Impact

Organised crime is changing and becoming increasingly diverse in its methods, group structures and impact on society. This article aims to research, on the one hand, the impact of organized crime on state’s economy, on the other hand – to analyse the possible legal and economic measures tackling and preventing organized crime activities. The article contains results of the analysis of international, regional and national legal acts and the secondary analysis of statistical data of European Union agencies and international organizations. The author used a variety of methods: from selection and analysis of primary and secondary sources to descriptive, comparative and synthesis methods. Such analysis required multitudinous, broad and diverse base of empirical data, which were collected from the international, regional, national organizations and agencies, as well as scientific, operational and theoretical reports related to the issue of organised crime and impact of this phenomenon to the state and the society.

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The influence of culture on disclosures in financial statements prepared under International Financial Reporting Standards

Zeszyty Teoretyczne Rachunkowości ◽

10.5604/01.3001.0013.0758 ◽

2019 ◽

Vol 2019 (101 (157)) ◽

pp. 111-132 ◽

Cited By ~ 1

Author(s):

Jerzy Gierusz ◽

Katarzyna Koleśnik

Keyword(s):

Financial Reporting ◽

Comparative Studies ◽

Financial Statements ◽

Arab Countries ◽

International Financial Reporting Standards ◽

Reporting Standards ◽

Consolidated Financial Statements ◽

Financial Reporting Standards ◽

Financial Disclosures ◽

The Impact

The primary objective of this article is to investigate the impact of culture (as measured by Hofstede) on disclosures in financial statements prepared under International Financial Reporting Standards (IFRS) by firms from different countries. The sample comprises 2011−2013 consolidated financial statements of stock companies (excluding banks, insurance, and other financial institutions) from four countries repre- senting different cultural areas: the United Kingdom (Anglo), Germany (Germanic), Poland (Central Eastern Europe; CEE) and Kuwait (Arab). The research material came from 312 annual consolidated financial statements from 104 companies. The results reveal that cultural values have a significant impact on financial disclosures even after the use of IFRS. The paper is one of the few comparative studies attempting to assess the effects of culture on financial disclosures in Western Europe countries, CEE countries and Arab countries. Most of the international comparative studies in this research area have neglected CEE and Arab countries.

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Early palliative care in haematological patients: a systematic literature review

BMJ Supportive & Palliative Care ◽

10.1136/bmjspcare-2020-002386 ◽

2020 ◽

Vol 10 (4) ◽

pp. 395-403

Author(s):

Silvia Tanzi ◽

Francesco Venturelli ◽

Stefano Luminari ◽

Franco Domenico Merlo ◽

Luca Braglia ◽

...

Keyword(s):

Palliative Care ◽

Comparative Studies ◽

English Language ◽

Meta Analysis ◽

Early Palliative Care ◽

Study Results ◽

Registration Number ◽

Integrated Or ◽

The Impact

BackgroundEarly palliative care together with standard haematological care for advanced patients is needed worldwide. Little is known about its effect. The aim of the review is to synthesise the evidence on the impact of early palliative care on haematologic cancer patients’ quality of life and resource use.Patients and methodsA systematic review was conducted. The search terms were early palliative care or simultaneous or integrated or concurrent care and haematological or oncohaematological patients. The following databases were searched: PubMed, Embase, Cochrane, CINHAL and Scopus. Additional studies were identified through cross-checking the reference articles. Studies were in the English language, with no restriction for years. Two researchers independently reviewed the titles and abstracts, and one author assessed full articles for eligibility.ResultsA total of 296 studies titles were reviewed. Eight articles were included in the synthesis of the results, two controlled studies provided data on the comparative efficacy of PC interventions, and six one-arm studies were included. Since data pooling and meta-analysis were not possible, only a narrative synthesis of the study results was performed. The quality of the two included comparative studies was low overall. The quality of the six non-comparative studies was high overall, without the possibility of linking the observed results to the implemented interventions.ConclusionsStudies on early palliative care and patients with haematological cancer are scarce and have not been prospectively designed. More research on the specific population target, type and timing of palliative care intervention and standardisation of collected outcomes is required.PROSPERO registration numberCRD42020141322.

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