Influence of high intensity ultrasound on microbial reduction, physico-chemical characteristics and fermentation of sweet whey

The paper presents the synthesis of a new complex combination of a Bis-Schiff base with Mn(II) ions with great potential for antimicrobial and anti-inflammatory activity. A new complex of the Salen-type ligand, 1-ethyl-salicylidene-bis-ethylene diamine was synthetized using Mn(II) ions. The chemical structure was confirmed through 1H-NMR and IR spectroscopy. The antimicrobial activities of the Bis-Schiff base and its complex were tested in comparison with Ampicillin, Chloramphenicol, Tetracycline, Ofloxacin and Nystatin. Those compounds were found to be active against Gram-positive or Gram-negative bacteria, and had an anti-inflammatory effect comparable to that of Indomethacin.

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Progress and Prospects in Translating Nanobiotechnology in Medical Theranostics

Current Nanoscience ◽

10.2174/1573413715666191126093258 ◽

2020 ◽

Vol 16 (5) ◽

pp. 685-707 ◽

Cited By ~ 1

Author(s):

Amna Batool ◽

Farid Menaa ◽

Bushra Uzair ◽

Barkat Ali Khan ◽

Bouzid Menaa

Keyword(s):

Biological Properties ◽

Chemical Characteristics ◽

Intrinsic Properties ◽

The Past ◽

Profound Influence ◽

Functionalized Nanomaterials ◽

Physico Chemical ◽

Properties Of Materials ◽

Targeted Drug ◽

And Performance

: The pace at which nanotheranostic technology for human disease is evolving has accelerated exponentially over the past five years. Nanotechnology is committed to utilizing the intrinsic properties of materials and structures at submicroscopic-scale measures. Indeed, there is generally a profound influence of reducing physical dimensions of particulates and devices on their physico-chemical characteristics, biological properties, and performance. The exploration of nature’s components to work effectively as nanoscaffolds or nanodevices represents a tremendous and growing interest in medicine for various applications (e.g., biosensing, tunable control and targeted drug release, tissue engineering). Several nanotheranostic approaches (i.e., diagnostic plus therapeutic using nanoscale) conferring unique features are constantly progressing and overcoming all the limitations of conventional medicines including specificity, efficacy, solubility, sensitivity, biodegradability, biocompatibility, stability, interactions at subcellular levels. : This review introduces two major aspects of nanotechnology as an innovative and challenging theranostic strategy or solution: (i) the most intriguing (bare and functionalized) nanomaterials with their respective advantages and drawbacks; (ii) the current and promising multifunctional “smart” nanodevices.

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The effect of leaf age and drying method on physico-chemical characteristics of pandan (Pandanus amaryllifolius Roxb.) leaves powder

IOP Conference Series Earth and Environmental Science ◽

10.1088/1755-1315/733/1/012073 ◽

2021 ◽

Vol 733 (1) ◽

pp. 012073

Author(s):

A Adhamatika ◽

E S Murtini ◽

W B Sunarharum

Keyword(s):

Leaf Age ◽

Chemical Characteristics ◽

Drying Method ◽

Physico Chemical ◽

Pandanus Amaryllifolius

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Sensorial, Melissopalynological and Physico-Chemical Characteristics of Honey from Babors Kabylia’s Region (Algeria)

Foods ◽

10.3390/foods10020225 ◽

2021 ◽

Vol 10 (2) ◽

pp. 225

Author(s):

Asma Ghorab ◽

María Shantal Rodríguez-Flores ◽

Rifka Nakib ◽

Olga Escuredo ◽

Latifa Haderbache ◽

...

Keyword(s):

Sensory Properties ◽

Chemical Components ◽

Chemical Characteristics ◽

Pollen Spectrum ◽

Botanical Origin ◽

Flavonoid Content ◽

Chemical Parameters ◽

High Tendency ◽

Physico Chemical ◽

Pollen Types

This study aimed to characterize the honeys of Babors Kabylia through sensory, melissopalynological and physico-chemical parameters. Thirty samples of honey produced in this region were collected over a period of two years and analyzed. All the samples presented physico-chemical parameters in conformity with legislation on honey quality, with few exceptions, linked mainly to beekeeping management. The pollen spectrum revealed a great diversity with 96 pollen types. The main pollen types were spontaneous species as Fabaceae (Hedysarum, Trifolium, Genisteae plants), Asteraceae plants, Ericaceae (Erica arborea L.) or Myrtus and Pistacia. The sensory properties of samples showed a high tendency to crystallization, the colors were from white to brown, but most of them had gold color. Smell and odor corresponded mainly to vegetal and fruity families and in taste perceptions besides sweetness highlighted sourness and saltiness notes. Seventeen samples were polyfloral, one was from honeydew and twelve were monofloral from heather, genista plants, sulla, blackberry or Asteraceae. Heather and the honeydew samples showed the darkest color, the highest electrical conductivity and phenol and flavonoid content. A statistical analysis based on the most representative pollen types, sensory properties and some physico-chemical components allowed the differentiation of honey samples in terms of botanical origin.

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Non pharmacological high-intensity ultrasound treatment of human dermal fibroblasts to accelerate wound healing

Scientific Reports ◽

10.1038/s41598-021-81878-1 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Jeong Yu Lee ◽

Dae-Jin Min ◽

Wanil Kim ◽

Bum-Ho Bin ◽

Kyuhan Kim ◽

...

Keyword(s):

Wound Healing ◽

High Intensity ◽

Mapk Pathway ◽

Dermal Fibroblasts ◽

Ultrasound Treatment ◽

Type I ◽

Human Dermal Fibroblasts ◽

Short Term ◽

High Intensity Ultrasound ◽

Extracellular Matrix Components

AbstractInspired by the effectiveness of low-intensity ultrasound on tissue regeneration, we investigated the potential effect of short-term high-intensity ultrasound treatment for acceleration of wound healing in an in vitro wound model and dermal equivalent, both comprising human dermal fibroblasts. Short-term ultrasound of various amplitudes significantly increased the proliferation and migration of fibroblasts and subsequently increased the production of the extracellular matrix components fibronectin and collagen type I, both of which are important for wound healing and are secreted by fibroblasts. In addition, ultrasound treatment increased the contraction of a fibroblast-embedded three-dimensional collagen matrix, and the effect was synergistically increased in the presence of TGF-β. RNA-sequencing and bioinformatics analyses revealed changes in gene expression and p38 and ERK1/2 MAPK pathway activation in the ultrasound-stimulated fibroblasts. Our findings suggest that ultrasound as a mechanical stimulus can activate human dermal fibroblasts. Therefore, the activation of fibroblasts using ultrasound may improve the healing of various types of wounds and increase skin regeneration.

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