scholarly journals Consumption of virgin coconut oil in Wistar rats increases saturated fatty acids in the liver and adipose tissue, as well as adipose tissue inflammation

2018 ◽  
Vol 48 ◽  
pp. 472-480 ◽  
Author(s):  
Mariana de Moura e Dias ◽  
Nathane Pais Siqueira ◽  
Lisiane Lopes da Conceição ◽  
Sandra Aparecida dos Reis ◽  
Flávia Xavier Valente ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Adipose Tissue ◽  
Wistar Rats ◽  
Saturated Fatty Acids ◽  
Coconut Oil ◽  
Adipose Tissue Inflammation ◽  
Virgin Coconut Oil ◽  
Tissue Inflammation

scholarly journals Adipose Tissue Remodeling as Homeostatic Inflammation

2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Michiko Itoh ◽  
Takayoshi Suganami ◽  
Rumi Hachiya ◽  
Yoshihiro Ogawa
Keyword(s):  
Fatty Acids ◽  
Adipose Tissue ◽  
Inflammatory Responses ◽  
Saturated Fatty Acids ◽  
Tissue Remodeling ◽  
Low Grade ◽  
Adipose Tissue Inflammation ◽  
Tissue Inflammation ◽  
Adipose Tissue Remodeling ◽  
Novel Therapeutic Strategies

Evidence has accumulated indicating that obesity is associated with a state of chronic, low-grade inflammation. Obese adipose tissue is characterized by dynamic changes in cellular composition and function, which may be referred to as “adipose tissue remodeling”. Among stromal cells in the adipose tissue, infiltrated macrophages play an important role in adipose tissue inflammation and systemic insulin resistance. We have demonstrated that a paracrine loop involving saturated fatty acids and tumor necrosis factor-α derived from adipocytes and macrophages, respectively, aggravates obesity-induced adipose tissue inflammation. Notably, saturated fatty acids, which are released from hypertrophied adipocytes via the macrophage-induced lipolysis, serve as a naturally occurring ligand for Toll-like receptor 4 complex, thereby activating macrophages. Such a sustained interaction between endogenous ligands derived from parenchymal cells and pathogen sensors expressed in stromal immune cells should lead to chronic inflammatory responses ranging from the basal homeostatic state to diseased tissue remodeling, which may be referred to as “homeostatic inflammation”. We, therefore, postulate that adipose tissue remodeling may represent a prototypic example of homeostatic inflammation. Understanding the molecular mechanism underlying homeostatic inflammation may lead to the identification of novel therapeutic strategies to prevent or treat obesity-related complications.

Effects of dietary fatty acids on lipogenesis and lipid traits in muscle, adipose tissue and liver of growing rabbits

1998 ◽  
Vol 66 (2) ◽  
pp. 483-489 ◽  
Author(s):  
F. Gondret ◽  
J. Mourot ◽  
F. Lebas ◽  
M. Bonneau
Keyword(s):  
Fatty Acids ◽  
Adipose Tissue ◽  
Polyunsaturated Fatty Acids ◽  
Lipid Content ◽  
Saturated Fatty Acids ◽  
Coconut Oil ◽  
Basal Diet ◽  
Dietary Fatty Acids ◽  
Medium Chain ◽  
Perirenal Fat

AbstractThe effects of fat source on lipogenesis and lipid traits of longissimus muscle, liver and perirenal adipose tissue, were studied in 48 New Zealand White rabbits, slaughtered at 11 or 15 weeks of age. Rabbits were offered diets with 20 g added fat per kg, containing either medium-chain (COC: coconut oil), saturated and monounsaturated (PAL: palm oil) or polyunsaturated (SUN: sunflower oil) fatty acids as major components. Diets did not affect growth performance, dressing proportion and tissue weights. Intramuscular lipid content was lower for COC than for SUN and PAL (e.g. 10 v. 13 and 12 glkg, at 11 weeks, respectively, P < 0·05), whereas lipid content was unaffected by diet in liver and perirenal fat. In muscle, the fat source did not influence the activities of acetyl-CoA-carboxylase (CBX), malic enzyme (ME) and glucose-6-phosphodehydrogenase (G6PDH). In liver, activities ofGSPDH and ME were depressed from the SUN diet, as compared with the COC or PAL diets. The diet-induced variations in enzyme activities in perirenal fat were lower than in the liver and were not significant. Medium-chain fatty acids were found only in tissue lipids of animals given COC. The ratio of polyunsaturated to saturated fatty acids decreased in the order SUN > PAL > COC in muscle and perirenal fat. Thus, polyunsaturated fatty acids exert an inhibition of G6PDH and ME activities specifically in liver. Compared with COC, the addition of SUN to the basal diet increased total lipids and polyunsaturated fatty acids contents in the longissimus lumborum muscle, which might improve the organoleptic and dietetic qualities of rabbit meat.

scholarly journals The Effect of Giving Virgin Coconut Oil (VCO) to Changes in Lauric Acid Levels in Breast Milk

2021 ◽  
Vol 5 (2) ◽  
pp. 233-243
Author(s):  
Ismul Sadly Putra ◽  
Joserizal Serudji
Keyword(s):  
Fatty Acids ◽  
Breast Milk ◽  
Lauric Acid ◽  
Metabolic Pathways ◽  
Saturated Fatty Acids ◽  
Coconut Oil ◽  
The Body ◽  
Virgin Coconut Oil ◽  
Nutritional Components ◽  
Anti Fungal

Breastmilk (ASI) is the best food produced by the breast glands, containing all the nutritional elements needed by infants aged 0-6 months. Apart from nutrients, breast milk also has other non-nutritional components that act as immune factors for babies. Babies who are not exclusively breastfed will be more susceptible to chronic diseases, such as heart disease, hypertension, and diabetes as adults and can suffer from malnutrition and obesity. Dietary intake significantly affects milk production. The mother's diet can affect the composition of her milk through several metabolic pathways, especially the concentration of fatty acids and vitamins that are soluble in fat and water, including vitamins A, C, B6, and B12. Lauric acid contained in breast milk can help your minor fight infection and increase immunity to protect from various diseases. Not only for the baby, but virgin coconut oil is also starting to be commonly used by dieters. Virgin coconut oil contains lauric acid CH3 (CH2) 10COOH 50% and caprylic acid CH3 (CH2) 6COOH 7%. Both of these acids are medium-chain saturated fatty acids that are quickly metabolized and have anti-microbial properties. The benefits of virgin coconut oil (VCO) are that it is beneficial for the health of the body, including being antibacterial, antiviral, anti-fungal, and natural anti-protozoa; helps relieve symptoms and reduces health risks associated with diabetes, helps protect against osteoporosis, helps prevent high blood pressure, helps prevent liver disease, keeps the heart and blood vessels healthy, helps prevent cancer, helps you lose weight, maintain stamina, maintain healthy skin and hair.Keywords: Breastmilk, Lauric Acid, VCO

scholarly journals Analysis of Fatty Acids in Virgin Coconut Oil Frying at Various Temperatures

2021 ◽  
Vol 10 (1) ◽  
pp. 104
Author(s):  
Dewa Ayu Ika Pramitha ◽  
I Wayan Karta
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Acid Content ◽  
Saturated Fatty Acids ◽  
Fatty Acid Content ◽  
Medium Chain Triglyceride ◽  
Coconut Oil ◽  
Virgin Coconut Oil ◽  
Medium Chain ◽  
Cooking Oil

Fatty acid content from virgin coconut oil (VCO) is a medium-chain triglyceride (MCT) group. MCT is stable at very low and high temperatures, and the color does not turn black due to the addition of heat so that it can be developed into beneficial cooking oil for health. Therefore, a study was conducted on the content of fatty acids in VCO after being heated at temperatures of 150, 200, and 250°C for 60 minutes. Analysis of fatty acid content in control VCO(T0), VCO with heating temperatures of 150oC(T1), 200oC(T2), and 250oC(T3) was performed with GCMS QP-2010 Ultra.The results showed that there were differences in levels and types of fatty acids in VCO by treating T0, T1, T2, and T3. At these three temperatures still produce medium-chain saturated fatty acids and trans fatty acids are not produced, so that VCO can be utilized as cooking oil that has better stability and benefits for health.

scholarly journals Dietary fatty acids and adipose tissue inflammation at the crossroad between obesity and colorectal cancer

2019 ◽  
Vol 2019 ◽  
Author(s):  
Lucia Conti ◽  
Manuela Del Corn�� ◽  
Beatrice Scazzocchio ◽  
Rosaria Var�� ◽  
Massimo D��Archivio ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Fatty Acids ◽  
Adipose Tissue ◽  
Dietary Fatty Acids ◽  
Adipose Tissue Inflammation ◽  
Tissue Inflammation

scholarly journals (n-3) Fatty Acids Alleviate Adipose Tissue Inflammation and Insulin Resistance: Mechanistic Insights

2011 ◽  
Vol 2 (4) ◽  
pp. 304-316 ◽  
Author(s):  
Nishan S. Kalupahana ◽  
Kate J. Claycombe ◽  
Naima Moustaid-Moussa
Keyword(s):  
Insulin Resistance ◽  
Fatty Acids ◽  
Adipose Tissue ◽  
Adipose Tissue Inflammation ◽  
Tissue Inflammation

Review: Asam Lemak Virgin Coconut Oil (VCO) dan Manfaatnya untuk Kesehatan

2020 ◽  
Vol 4 (1) ◽  
pp. 93
Author(s):  
Melati Ananda Kusuma ◽  
Nia Ariani Putri
Keyword(s):  
Fatty Acids ◽  
Literature Review ◽  
Systematic Literature Review ◽  
Unsaturated Fatty Acids ◽  
Saturated Fatty Acids ◽  
Coconut Oil ◽  
Caproic Acid ◽  
Biological Functions ◽  
Virgin Coconut Oil ◽  
High Heating

Coconut plant is often called the plant of life because every part of the coconut plant can be used and processed into a product. One of the commercially processed coconut products, namely Virgin Coconut Oil (VCO), which is believed to have health properties. This article is written based on the results of a systematic literature review which relies on literature studies on the topic of virgin coconut oil. Virgin coconut oil is produced from fresh coconut flesh (non-copra), the processing process is not through a chemical process and does not use high heating so that the characteristics of the oil produced are clear (clear) and have a distinctive aroma of coconut. The fatty acids contained in VCO are saturated and unsaturated fatty acids. The components included in saturated fatty acids are caproic acid, caprylic acid, myristic acid, palmitic acid and lauric acid; while the unsaturated fatty acid components are cyclopropanpentanoic acid, oleic acid, and stearic acid. VCO contains short and medium-chain fatty acids which are known to have certain biological functions for the human body. These benefits include its functions as anti-bacterial and anti-fungal.Tanaman kelapa sering dijuluki sebagai tanaman kehidupan karena setiap bagian dari tanaman kelapa dapat dimanfaatkan dan diolah menjadi suatu produk. Salah satu produk olahan kelapa komersial yaitu Virgin Coconut Oil (VCO) yang dipercaya memiliki khasiat untuk kesehatan. Artikel ini ditulis berdasarkan hasil tinjauan pustaka sistematis (systematic literature review) yang mengandalkan studi pustaka dengan topik mengenai minyak kelapa murni. VCO dihasilkan dari daging buah kelapa segar (non kopra) yang proses pengolahannya tidak melalui proses kimiawi dan tidak menggunakan pemanasan tinggi, sehingga karakteristik minyak yang dihasilkan berwarna bening (jernih) serta beraroma khas kelapa. Asam lemak yang terkandung dalam VCO tersebut merupakan asam lemak jenuh dan tak jenuh. Komponen yang termasuk dalam asam lemak jenuh yaitu, asam kaproat, asam kaprilat, asam miristat, asam palmitat dan asam laurat; sedangkan komponen asam lemak tak jenuh yaitu asam siklopropanpentanoat, asam oleat, dan asam stearat. VCO mengandung asam lemak rantai pendek dan menengah atau medium yang diketahui mempunyai fungsi biologis tertentu bagi tubuh manusia. Manfaat tersebut meliputi fungsi sebagai anti bakteri dan anti jamur.

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