The difference between induction and maintenance dosages of propofol for general anesthesia in patients with and without sleep quality disorder

ABSTRACTBackground : Early mobilization is some effort to defend autonomy as early as possible by guiding the victim for defending fisiologis function (Carpenito, 2001). According Smeltzer Bare (2002) in patient with colon inflammation disturbance, explained that change position encourage doing passive and active exercise to depend muscle and prevent tromboembolic. Activity limitation changed suitable with daily necessary. General anesthesia can cause decreasing colon movement with stimuli parasympatic obstruction in colon muscle. Client with local anesthesia will experience same case. Direction surgery which involved intestinal can cause stopping intestinal while movement. Surgery action with general anesthesia in RS.DR.R.Soeprapto Cepuoften was being done in juny – December 2012 period reported 166 cases.Objective : This study to determine the difference of early mobilization 6 hours and 8 hours toward intestine peristaltic on post operation patient with general anesthesia at RSUD dr. R. Soeprapto Cepu. Methods : Method of this research used quasi eksperimental design and taking sampling method was stratified random sampling, research was done into 20 respondences. Collecting data technique using observation technique. Statistic analysis used Independent t-test exam, organize and data analysis with computer program assist SPSS for windows 16.Result : The result analysis was shown with independent t-test exam was be found t hitung 0,662, t table 2,101, p value 0,641. Where is t hitung t table (0,662 2,101) and p value alpha (0,641 0,05) above can be conclude Ho was accepted. Its mean its’nt difference early mobilization 6 hours and 8 hours about peristaltic of intestine for post operation patient with general anesthesia in dr.R.Soeprapto Cepu Hospitals.Conclusion : Advice we recommend early mobilization of patients immediately after surgery with general anesthesia, according to the results of this study was able to mobilize patients early in the post anesthesia 6 hours. Keywords: mobilisation, peristaltic of intestine, post operation, general anesthesia.

Download Full-text

THE DIFFERENCE IN ADDITION OF BACK MASSAGE COMBINATION IN PREGNANCY EXERCISE IN IMPROVING QUALITY OF SLEEP IN THIRD TRIMESTER PREGNANT WOMEN

Majalah Ilmiah Fisioterapi Indonesia ◽

10.24843/mifi.2018.v06.i02.p03 ◽

2018 ◽

Vol 6 (2) ◽

pp. 16

Author(s):

Mezzi Wulandari Arenza ◽

Ni Wayan Tianing ◽

I Putu Adiartha Griadhi

Keyword(s):

Sleep Quality ◽

Pregnant Women ◽

Control Group ◽

Quality Of Sleep ◽

Third Trimester ◽

The Third ◽

The Difference ◽

In Pregnancy ◽

Back Massage

ABSTRACTSleep disturbance in the third trimester pregnant women is caused by discomfort, an increasingly largeabdominal condition, back pain, frequent urination, fetal movement, heartburn, cramps in the legs, tiredness, difficultygetting started, and physiological changes. Sleep disorders result in decreased quality of sleep. Pregnant women whohave poor sleep quality are at risk of longer labor, cesarean delivery, premature birth, and even infant mortality. The aimof this research is to know the difference of pregnant exercise combination and back massage in improving the sleepquality of third trimester pregnant women. This research use experiment method with quasi experiment approach andresearch design is pre and post test with control design. Sample are 18 people, divided into 2 groups, 9 people intreatment groups given pregnancy exercise and back massage and 9 people in control group is given only pregnantexercise. Intervention is given 8 times. Pittsburgh Sleep Quality Index (PSQI) questionnaire used for measured of sleepquality. The result of different test of unpaired group, in the treatment group got difference of average 4,556 and controlgroup got difference mean 2,333 with p=0,004 (p<0,05). These results showed that there was a significant differencebetween the treatment group and the control group in improving the sleep quality of the third trimester pregnant women.In conclusion, there are differences in the addition of back massage combination in pregnancy exercise intervention inimproving sleep quality of third trimester pregnant women.Keyword : Pregnancy Exercise, Back Massage, Sleep Quality, Third Trimester.

Download Full-text

Active Emergence from Propofol General Anesthesia Is Induced by Methylphenidate

Anesthesiology ◽

10.1097/aln.0b013e3182518bfc ◽

2012 ◽

Vol 116 (5) ◽

pp. 998-1005 ◽

Cited By ~ 67

Author(s):

Jessica J. Chemali ◽

Christa J. Van Dort ◽

Emery N. Brown ◽

Ken Solt

Keyword(s):

Spectral Analysis ◽

Single Dose ◽

General Anesthesia ◽

Median Time ◽

Molecular Mechanisms ◽

General Anesthetics ◽

Adult Rats ◽

Before And After ◽

Target Plasma Concentration ◽

The Difference

Background A recent study showed that methylphenidate induces emergence from isoflurane general anesthesia. Isoflurane and propofol are general anesthetics that may have distinct molecular mechanisms of action. The objective of this study was to test the hypothesis that methylphenidate actively induces emergence from propofol general anesthesia. Methods Using adult rats, the effect of methylphenidate on time to emergence after a single bolus of propofol was determined. The ability of methylphenidate to restore righting during a continuous target-controlled infusion (TCI) of propofol was also tested. In a separate group of rats, a TCI of propofol was established and spectral analysis was performed on electroencephalogram recordings taken before and after methylphenidate administration. Results Methylphenidate decreased median time to emergence after a single dose of propofol from 735 s (95% CI: 598-897 s, n = 6) to 448 s (95% CI: 371-495 s, n = 6). The difference was statistically significant (P = 0.0051). During continuous propofol anesthesia with a median final target plasma concentration of 4.0 μg/ml (95% CI: 3.2-4.6, n = 6), none of the rats exhibited purposeful movements after injection of normal saline. After methylphenidate, however, all six rats promptly exhibited arousal and had restoration of righting with a median time of 82 s (95% CI: 30-166 s). Spectral analysis of electroencephalogram data demonstrated a shift in peak power from δ (less than 4 Hz) to θ (4-8 Hz) and β (12-30 Hz) after administration of methylphenidate, indicating arousal in 4/4 rats. Conclusions Methylphenidate decreases time to emergence after a single dose of propofol, and induces emergence during continuous propofol anesthesia in rats. Further study is warranted to test the hypothesis that methylphenidate induces emergence from propofol general anesthesia in humans.

Download Full-text

The relationship between sleep quality and nutrition of medical school students in a city of Turkey

European Journal of Public Health ◽

10.1093/eurpub/ckz186.437 ◽

2019 ◽

Vol 29 (Supplement_4) ◽

Author(s):

E Pehlivan ◽

E Yalcin ◽

B Firinci

Keyword(s):

Body Mass Index ◽

At Risk ◽

Social Media ◽

Sleep Quality ◽

Body Mass ◽

Eating Attitudes ◽

Eating Attitude ◽

Normal Body Mass Index ◽

Normal Body ◽

The Difference

Abstract Background Students need quality sleep and regular feeding during an intensive training proces. The aim of this study was to determine the sleep quality of Faculty of Medicine students and whether there is a relationship between sleep quality and eating attitudes and habits. Methods In this cross-sectional study; a face-to-face questionnaire was administered to 352 students who attending Inonu University Medical Faculty between January and March of 2019. The sample group is stratified according to class sizes (total 1665 students. The sleep quality and eating behaviors of students were questioned. For purpose, Pittsburgh Sleep Quality Index (PUKI, developed by Buysse et al,1989), and Eating Attitude Test (EAT,developed by Garner et al 1982) was used to assess quality and disorders. Kolmogorov Smirnov normal distribution test, Mann Whitney U and Kruskal Wallis test were used in analysis of the data. Results The mean age of the students was 21.5 ± 2.5 and 54.3% were female and 45.7% were male and 25.0% smoked cigarette. 64.4% of the study group had normal body mass index. The median value of the PUKI (cut of point is 5.0 and under 5 is good) score by gender is similar with 6.0 (1.0-15.0). The median value of the PUKI score was 6.0 (1.0-16.0) in social media / internet users and 5.0 (1.0-13.0) in non-users. According to Internet / social media users before going to sleep, the difference is significant (p: 0.016). The difference between cigarette smoking and median value of PUKI was significant (p: 0.029). there was a difference between classes in favor of upper classes in terms of EAT values (p = 0,046). 12.2% of the students are at risk of Blumia and 10.8% are at risk of Anorexia. There was no significant but positive correlation between the PUKI and EAT (p = 0.074, r = 0.096). Conclusions In general, the students’ sleep quality and eating attitudes and habits were found close to the cut-off points accepted by the tests. But blumia and anorexia is significant. This study was supported by the Research Fund of the Inonu University (No. 1792) Key messages Social media / internet usage of students before going to sleep affects sleep quality significantly. Although 64.4% of the students have normal body mass index, eating disorders (bulumia and anorexia) risk are noteable.

Download Full-text

Sleep Pattern Changes in Nursing Students during the COVID-19 Lockdown

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph17145222 ◽

2020 ◽

Vol 17 (14) ◽

pp. 5222 ◽

Cited By ~ 3

Author(s):

Cristina Romero-Blanco ◽

Julián Rodríguez-Almagro ◽

María Dolores Onieva-Zafra ◽

María Laura Parra-Fernández ◽

María del Carmen Prado-Laguna ◽

...

Keyword(s):

Nursing Students ◽

Sleep Quality ◽

Nonparametric Tests ◽

Normal Weight ◽

Lifestyle Changes ◽

Poor Sleep ◽

First Year Students ◽

Time In Bed ◽

The Difference ◽

Stratified Analysis

The prevalence of poor sleep quality among students is very high and, in nursing students, has been associated with reduced performance, behavioral changes, dietary changes, and even aggressive behavior due to changes in sleep patterns. The lockdown in response to COVID-19 may have resulted in lifestyle changes that affected sleep quality. For this reason, the objective of this study is to determine the difference in nursing students’ sleep quality before and during the lockdown, put in place in response to the coronavirus (COVID-19) pandemic. To meet this objective, we conducted a longitudinal observational study on 207 nursing students, with two cut-off points (February and April). The main dependent variable was sleep quality, measured using the Pittsburgh sleep quality index (PSQI) and its seven components. Parametric and nonparametric tests were used for paired and unpaired data, as well as group-stratified analysis. The mean time students spent in bed was 7.6 h (standard deviation (SD) = 1.1 h) before lockdown and 8.5 h (SD = 1.2 h) during lockdown. The PSQI score got 0.91 points worse during lockdown (95% CI, −0.51, −1.31). Of the five components, five were statistically significantly affected (p ≤ 0.05), and of these, the most changed were sleep latency, sleep duration, and sleep efficiency. When stratified by group, we observed differences in women, first-year students, second-year students, alcohol consumers, those of normal weight, and those that live with family. The main conclusion is that although students spent more time in bed, overall sleep quality was worse during lockdown, as well as being worse in five of the seven components.

Download Full-text

Activity, duration of rest, daytime sleepiness and sleep quality in schizophrenia patients treated with sertindole and olanzapine

European Psychiatry ◽

10.1016/s0924-9338(11)73234-5 ◽

2011 ◽

Vol 26 (S2) ◽

pp. 1530-1530

Author(s):

A. Wichniak ◽

A. Wierzbicka ◽

K. Czasak ◽

I. Musińska ◽

T. Jakubczyk ◽

...

Keyword(s):

Sleep Quality ◽

Daytime Sleepiness ◽

Sedative Effect ◽

Sleep Diaries ◽

Athens Insomnia Scale ◽

Time In Bed ◽

Activity Duration ◽

Increased Risk ◽

Medication Side ◽

The Difference

ObjectivesLow activity and long rest times are frequent in patients with schizophrenia and are related to increased risk for metabolic disorder. We investigated whether patients who were switched from sedative antipsychotics to sertindole, an antipsychotic drug without sedative effect, were more active than patients with good tolerance to sedative effect of olanzapine.Methods18 patients with schizophrenia treated with sertindole (9 females, mean age 27.9 ± 4,1, mean dose 15.6 ± 3.0 mg/d) and 18 sex and age matched patients treated with olanzapine (mean dose 15.3 ± 6.5 mg/d) underwent actigraphy for seven days. Daytime sleepiness and sleep quality were evaluated with Epworth Sleepiness Scale (ESS), Athens insomnia scale (AIS) and sleep diaries. PANSS, UKU, BARS scales were used to rate mental state and medication side effects.ResultsAt the time of the assessment PANNS score was similar in sertindole (43.6 ± 7.1) and olanzapine (42.3 ± 12.2) groups. The difference in time in bed as measured by actigraphy was not significant between patients treated with sertindole (572.7 ± 54.8 min.) and olanzapine (600.6 ± 53.6 min.). Also mean 24-h-activity was comparable in both groups (86.6 ± 29.6 and 81.6 ± 27.9 units, respectively). There were not any significant differences in AIS and ESS scales.ConclusionsAlthough sertindole does not induce sedation, patients who were switched from sedative antipsychotics to sertindole were not more active than patients treated with olanzapine. Adjustment of pharmacological treatment has to be supplemented with non-pharmacological interventions to promote activity in patients with schizophrenia.

Download Full-text

Amphetamine Promotes Cortical Up State in Part Via Dopamine Receptors

Frontiers in Pharmacology ◽

10.3389/fphar.2021.728729 ◽

2021 ◽

Vol 12 ◽

Author(s):

Guofang Shen ◽

Wei-Xing Shi

Keyword(s):

General Anesthesia ◽

Dopamine Receptors ◽

Cortical Neurons ◽

Slow Wave Sleep ◽

Field Potential ◽

Promoting Effect ◽

Hyperactivity Disorder ◽

Co Activation ◽

Potential Recording ◽

The Difference

Cortical neurons oscillate between Up and Down states during slow wave sleep and general anesthesia. Recent studies show that Up/Down oscillations also occur during quiet wakefulness. Arousal eliminates Down states and transforms Up/Down oscillations to a persistent Up state. Further evidence suggests that Up/Down oscillations are crucial to memory consolidation, whereas their transition to a persistent Up state is essential for arousal and attention. We have shown that D-amphetamine promotes cortical Up state, and the effect depends on activation of central α1A adrenergic receptors. Here, we report that dopamine also plays a role in D-amphetamine’s effect. Thus, using local-field-potential recording in the prefrontal cortex in chloral hydrate-anesthetized rats, we showed that the Up-state promoting effect of D-amphetamine was attenuated by antagonists at either D1 or D2-like dopamine receptors. The effect was also partially mimicked by co-activation of D1 and D2-like receptors. These results are consistent with the fact that D-amphetamine increases the release of both norepinephrine and dopamine. They are also in agreement with studies showing that dopamine promotes wakefulness and mediates D-amphetamine-induced emergence from general anesthesia. The effect of D-amphetamine was not mimicked, however, by activation of either D1 or D2-like receptors alone, indicating an interdependence between D1 and D2-like receptors. The dopamine/norepinephrine precursor L-DOPA also failed to promote the Up state. While more studies are needed to understand the difference between L-DOPA and D-amphetamine, our finding may provide an explanation for why L-DOPA lacks significant psychostimulant properties and is ineffective in treating attention-deficit/hyperactivity disorder.

Download Full-text

Soaking Feet Hydrotherapy Using Warm Water to Improve Quality of Sleeping Among Pregnant Women

Jurnal Kebidanan dan Kesehatan Tradisional ◽

10.37341/jkkt.v0i0.232 ◽

2021 ◽

pp. 16-23

Author(s):

Ayu Wulandari ◽

Gita Kostania

Keyword(s):

Sleep Quality ◽

Pregnant Women ◽

Sampling Technique ◽

Warm Water ◽

Control Group ◽

Quality Of Sleep ◽

Control Group Design ◽

Before And After ◽

The Difference

Sleep is a basic need that must be fulfilled by humans. Sleep disorders often occur in pregnant women which has an impact on the quality of sleep. This study aims to identify the effect of soaking feet with warm water on the quality of sleep for pregnant women. This study used a quasi-experiment design with a nonequivalent control group design approach. The sampling technique used total sampling with 40 respondents who were in accordance with the eligible criteria. Interventions are given for 7 consecutive days. Measurement of sleep quality score using the Pittsburgh Sleep Quality Index questionnaire. The difference in sleep quality scores was analyzed by Mann Whitney test, and scores of each component were analyzed by using Wilcoxon test.The results of this study indicate the influence of soaking feet with warm water on sleep quality of respondents before and after the intervention (p = 0.007; α = 5%). From these results, it can be said that there was an increase in quality of sleep after soaking the feet with warm water. Hydrotherapy by soaking feet with warm water can be applied by pregnant women to improve sleep quality.

Download Full-text

Social Media Use and Sleep Quality among Adults: The Role of Gender, Age and Social Media Checking Habit

10.31234/osf.io/eqxdh ◽

2019 ◽

Cited By ~ 3

Author(s):

Liese Exelmans ◽

Holly Scott

Keyword(s):

Social Media ◽

Sleep Quality ◽

Technology Use ◽

Online Survey ◽

Media Use ◽

Poor Sleep ◽

Social Media Use ◽

Survey Results ◽

The Difference

This study expands knowledge on the effects of technology use on sleep by (1) focusing onsocial media use in an adult sample, (2) investigating the difference between overall andnighttime-specific social media use with regards to sleep, and (3) exploring a vulnerabilityperspective. For the latter, the moderating roles of gender, age, and habitual social mediachecking behavior were examined. A representative quota sample of 584 adults (18-96 yearsold) participated in an online survey. Results indicated that 2 out of 3 adults used socialmedia, and that use both shortly before and in bed was prevalent. Only nighttime use wasassociated with poorer sleep quality. Age and habitual checking behavior moderated thisassociation, identifying younger adults and those with strong checking habits as possiblevulnerable groups for poor sleep. The findings are interpreted in light of existing research onmedia habits and problematic (social) media use.

Download Full-text