A low fermentable oligo-di-mono saccharides and polyols(FODMAP) diet reduced pain and improve ddaily life in fibromyalgia patients

2016 ◽  
Vol 13 (1) ◽  
pp. 166-172 ◽  
Author(s):  
Ana Paula Marum ◽  
Cátia Moreira ◽  
Fernando Saraiva ◽  
Pablo Tomas-Carus ◽  
Catarina Sousa-Guerreiro
Keyword(s):  
Quality Of Life ◽  
Fibromyalgia Impact Questionnaire ◽  
Assessment Tools ◽  
Assessment Model ◽  
Dietary Therapy ◽  
Chi Square ◽  
Gi Symptoms ◽  
Significant Difference ◽  
Fodmap Diet

AbstractBackground and aimsFibromyalgia (FM) is a chronic, rheumatic disease characterized by widespread myofascial pain, of unknown aetiology, having a major impact on quality of life (QOL). Available pharmacotherapy for FM is marginally effective. FM is associated with co-morbidities of gastrointestinal (GI) disorders and Irritable Bowel Syndrome (IBS). There is growing evidence that diets low in FODMAPs, “fermentable oligo-, di- or mono-saccharides and polyols” [Low FODMAP Diet (LFD)], are effective in treating IBS. The aim of this pilot study was to examine the effects of LFDs on symptoms of FM, especially with regard to pain, QOL and GI disorders.MethodsA longitudinal study using LFD intervention was performed on 38, 51±10 year-old, female patients diagnosed with FM for an average of 10 years, based on ACR (American College of Rheumatology) 2010 criteria. The study was conducted from January through May, 2015, using a four-week, repeated-assessment model, as follows: Moment 0 – introduction of the protocol to participants; Moment 1 – first assessment and delivery of individual LFD dietary plans; Moment 2 – second assessment and reintroduction of FODMAPs; Moment 3 – last assessment and final nutritional counselling. Assessment tools used were the following: RFIQ (Revised Fibromyalgia Impact Questionnaire), FSQ (Fibromyalgia Survey Questionnaire), IBS-SSS (Severity Score System), EQ-5D (Euro-QOL quality of life instrument), and VAS (Visual Analogue Scale). Daily consumption of FODMAPs was quantified based on published food content analyses. Statistical analyses included ANOVA, non-parametric Friedman, t-student and Chi-square tests, using SPSS 22 software.ResultsThe mean scores of the 38 participants at the beginning of the study were: FSQ (severity of FM, 0–31) – 22±4.4; RFIQ (0–100) – 65±17; IBS-SSS (0–500) – 275± 101; and EQ-5D (0–100) – 48± 19. Mean adherence to dietary regimens was 86%, confirmed by significant difference in FODMAP intakes (25 g/day vs. 2.5 g/day; p < 0.01). Comparisons between the three moments of assessment showed significant (p < 0.01) declines in scores in VAS, FSQ, and RFIQ scores, in all domains measured. An important improvement was observed with a reduction in the severity of GI symptoms, with 50% reduction in IBS scores to 138±117, following LFD therapy. A significant correlation (r = 0.36; p < 0.05) was found between improvements in FM impact (declined scores) and gastrointestinal scores. There was also a significant correlation (r = 0.65; p < 0.01) between “satisfaction with improvement” after introduction of LFDs and “diet adherence”, with satisfaction of the diet achieving 77% among participants. A significant difference was observed between patients who improved as compared to those that did not improve (Chi-square χ2 = 6.16; p < .05), showing that the probability of improvement, depends on the severity of the RFIQ score.ConclusionsImplementation of diet therapy involving FODMAP restrictions, in this cohort of FM patients, resulted in a significant reduction in GI disorders and FM symptoms, including pain scores. These results need to be extended in future larger studies on dietary therapy for treatment of FM.ImplicationsAccording to current scientific knowledge, these are the first relevant results found in an intervention with LFD therapy in FM and must be reproduced looking for a future dietetic approach in FM.

scholarly journals AUTOAVALIAÇÃO DE IDOSOS QUE TRABALHAM SOBRE SUA QUALIDADE DE VIDA

2021 ◽  
Vol 9 (207) ◽  
pp. 1-20
Author(s):  
Felipe Queiroz Dias Rocha
Keyword(s):  
Quality Of Life ◽  
Energy Level ◽  
The Elderly ◽  
Chi Square ◽  
Work Activities ◽  
Significant Difference ◽  
Daily Energy ◽  
Chi Square Test ◽  
Good Feeling

Aging brings a series of changes that may result in: adaptation difficulties, need to treat limitations and alters that require treatment. The objective was to verify the quality of life of elders who still do work activities according to their own perspective. We got 36 seniors from São Paulo city to participate in the survey, with an average of 71.5 and ± 5.4. The data were randomly collected. For this, WHOQOL questionnaires were used. To discover if there is a statistically significant difference, the non-parametric Chi-square test was applied. As results: 30.55% of the elderly attend church Weekly; 44.44% classify the rate that pain prevents them of doing anything as Nothing; 41.66% say their daily energy level is Medium and 69.55% say they Totally Agree to having a good feeling about the future. It was verified that the elder workers are satisfied with their quality of life.

scholarly journals The effect of group-based education on gastrointestinal symptoms and quality of life in patients with celiac disease: randomized controlled clinical trial

2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Zahra Akbari Namvar ◽  
Reza Mahdavi ◽  
Masood Shirmohammadi ◽  
Zeinab Nikniaz
Keyword(s):  
Quality Of Life ◽  
Celiac Disease ◽  
Gastrointestinal Symptoms ◽  
Control Group ◽  
Post Intervention ◽  
Sf 36 ◽  
Gi Symptoms ◽  
Significant Difference ◽  
The Mean

Abstract Background In this trial, we investigated the effect of a group-based education program on gastrointestinal (GI) symptoms and quality of life (QOL) in patients with celiac disease (CD). Method In the present study, 130 patients with CD who were on a GFD for at least 3 months, randomly assigned to receive group-based education (n = 66) or routine education in the celiac clinic (n = 64) for 3 months. We assessed gastrointestinal symptoms and quality of life using the gastrointestinal symptom rating scale (GSRS) questionnaire and SF-36 questionnaire at baseline and 3 months after interventions. Results The mean age of the participants was 37.57 ± 9.59 years. There were no significant differences between the two groups regarding the baseline values. Results showed that the mean score of total GSRS score in the intervention group was significantly lower compared with the control group 3 months post-intervention (p = 0.04). Also, there was a significant difference in the mean score of SF-36 between the two groups 3 months post-intervention (p = 0.02). Conclusion Results showed that group-based education was an effective intervention in patients with celiac disease to improve gastrointestinal symptoms and quality of life. Trial registration IRCT code: IRCT20080904001197N21; registration date: 5/23/2019.

scholarly journals Cross Cultural Adaptation and Validation of Nigerian (Igbo) Version of the Older People’s Quality of Life Questionnaire (OPQOL-35): a Validation Study

2021 ◽  
Author(s):  
Ukamaka Gloria Mgbeojedo ◽  
Christopher Olusanjo Akosile ◽  
Chisom Cassandra Ekigbo ◽  
Emmanuel Chiebuka Okoye ◽  
Echezona Nelson Ekechukwu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Older Adults ◽  
Internal Consistency ◽  
Developed Countries ◽  
Assessment Tools ◽  
Active Ageing ◽  
Life Questionnaire ◽  
Health And Social Care ◽  
Significant Difference

Abstract Background Quality of life (QoL) has been revealed to determine an older adult’s assessment of successful and active ageing; and to evaluate various range of health and social care interventions. Most QoL assessment tools were developed for use in developed countries. This may not be suitable for developing nations such as Nigeria. There is need for availability of culture- and environment- specific tools for assessment of QoL. This study was therefore designed to cross-culturally adapt the OPQOL-35 into Igbo language, and determine its reliability and validity. Methods The original English OPQOL-35 (E-OPQOL-35) was translated into Igbo language, synthesized, back translated, and subsequently subjected to expert panel review, pre-testing and cognitive debriefing interview, following the American Academy of Orthopaedic Surgeons’ guideline. The final Igbo version (I-OPQOL-35) was tested for internal consistency, concurrent and structural validities in a cross-sectional study of 115 consenting apparently healthy older adults (54.8% females) that were recruited from conveniently selected local government areas in Enugu State, at 0.05 level of significance. Results The OPQOL-35 was cross-culturally adapted to Igbo with all its 35 items retained. The Spearman correlation coefficients between the participants’ domain and total scores on the I-OPQOL-35 and E-OPQOL-35 (rho = 0.92-1.00) were excellent. The Mann Whitney-U test revealed no significant difference between corresponding scores in the E-OPQOL-35 and I-OPQOL-35 (p = 0.65-0.94). The internal consistency coefficient of the I-OPQOL-35 was 0.78. Conclusions The I-OPQOL-35 is therefore a valid and reliable instrument for the assessment of QoL among Igbo older adults in Nigeria.

scholarly journals Use of Complementary and Alternative Medical Therapies in a Pediatric Neurology Clinic

2005 ◽  
Vol 32 (4) ◽  
pp. 524-528 ◽  
Author(s):  
Isaac Soo ◽  
Jean K. Mah ◽  
Karen Barlow ◽  
Lorie Hamiwka ◽  
Elaine Wirrell
Keyword(s):  
Quality Of Life ◽  
Side Effects ◽  
Neurological Disorders ◽  
Herbal Remedies ◽  
Dietary Therapy ◽  
Pediatric Neurology ◽  
Significant Difference ◽  
Neurology Clinic ◽  
Complementary And Alternative

ABSTRACT:Background:Complementary and alternative medicine (CAM) is increasingly used in adults and children. Studies on CAM in neurological disorders have focused on the adult population and its use among pediatric neurology patients has not been well characterized.Objectives:The purpose of this study was: 1) To characterize the prevalence of CAM in pediatric neurology patients; 2) To determine the perceived effectiveness of CAM in these children; 3) To compare the cost of CAM with conventional therapies; and 4) To describe caregiver or patient-related variables associated with the use of CAM.Methods:This was a cross-sectional survey of patients and families attending the Alberta Children's Hospital neurology clinic between February and May 2004. Patients were considered eligible if they were between two and 18 years of age and had a known history of neurological disorders. Caregivers completed several self-administered questionnaires regarding their socio-demographic profile, their child's neurological illness, and their experience with CAM. Caregivers also rated their child's quality of life using the Pediatric Quality of Life Inventory.Results:One hundred and five of 228 (46%) families completed the survey. The mean age of the neurology patients was 9.8 ± 4.5 years. Forty-six (44%) out of 105 patients received one or more types of CAM, with the most common types being chiropractic manipulations (15%), dietary therapy (12%), herbal remedies (8%), homeopathy (8%), and prayer/faith healing (8%). Caregivers' sociodemographic variables or pediatric health-related quality of life were not significantly associated with the use of CAM. Fifty-nine percent of CAM users reported benefits, and only one patient experienced side effects. There was no significant difference in the total median cost of CAM compared to conventional therapies ($31.70 vs. $50.00 per month). Caregivers' personal experience or success stories from friends and media were common reasons for trying CAM.Conclusions:The use of CAM was common among pediatric neurology patients. Over half of the families reported benefits with CAM, and side effects were perceived to be few. Physicians should initiate discussion on CAM during clinic visits so that the families and patients can make informed decisions about using CAM. Further studies should address the specific role of CAM in children with neurological disorders, and to determine the potential interactions between CAM and conventional therapies in these patients.

scholarly journals Efficacy of a low-FODMAP diet in adult irritable bowel syndrome: a systematic review and meta-analysis

2021 ◽  
Author(s):  
Anne-Sophie van Lanen ◽  
Angelika de Bree ◽  
Arno Greyling
Keyword(s):  
Quality Of Life ◽  
Gut Microbiome ◽  
Meta Analysis ◽  
Control Diet ◽  
Nutritional Adequacy ◽  
Gi Symptoms ◽  
Mean Differences ◽  
Irritable Bowel ◽  
Fodmap Diet

Abstract Purpose This review provides an updated overview of observational and intervention studies investigating the effect of a low-FODMAP (fermentable oligo-, di- and monosaccharides, and polyols) diet (LFD) on gastrointestinal (GI) symptoms, quality of life (QoL), nutritional adequacy, and gut microbiome in irritable bowel syndrome (IBS) patients. Methods We systematically searched available literature until October 2020 for studies that investigated the effect of LFDs on GI symptoms, QoL, nutritional adequacy, and the gut microbiome in IBS patients. The data were represented as standardized mean differences (SMD) for IBS severity, and as mean differences (MD) for IBS-QoL. Meta-analyses were performed for the quantitative analyses using random effects models with inverse variance weighing. Results Twelve papers (nine parallel trials, three crossover studies) were included for the meta-analysis. The LFD reduced IBS severity by a moderate-to-large extent as compared to a control diet (SMD − 0.66, 95% CI − 0.88, − 0.44, I2 = 54%). When analyzing only studies that used the validated IBS-SSS questionnaire, a mean reduction of 45 points (95% CI − 77, − 14; I2 = 89%) was observed. Subgroup analyses on adherence, age, intervention duration, IBS subtype, outcome measure, and risk of bias revealed no significantly different results. The LFD also increased IBS-QoL scores, when compared with a control diet (MD 4.93; 95% CI 1.77, 8.08; I2 = 42%). Conclusions The low-FODMAP diet reduces GI symptoms and improves quality of life in IBS subjects as compared to control diets. Future work is required to obtain definitive answers regarding potential long-term effects of such diets on nutritional adequacy and the gut microbiome. PROSPERO registration number CRD42020175157.

scholarly journals Association between living arrangement and quality of life for older adults in the community

2021 ◽  
Vol 29 ◽  
Author(s):  
Alisson Fernandes Bolina ◽  
Mayssa da Conceição Araújo ◽  
Vanderlei José Haas ◽  
Darlene Mara dos Santos Tavares
Keyword(s):  
Quality Of Life ◽  
Social Support ◽  
Older Adults ◽  
Living Arrangement ◽  
Death And Dying ◽  
Multiple Linear Regression Model ◽  
Chi Square ◽  
Cross Sectional ◽  
Significant Difference

Objective: to compare the sociodemographic and economic characteristics of the older adults in the community according to the living arrangement and to verify the association between the type of living arrangement and the quality of life scores. Method: a cross-sectional epidemiological study conducted with 796 older adults in the community. To assess quality of life (dependent variable), network and social support (adjustment variable), validated and applied chi-square tests, descriptive statistical analysis, multiple comparison analysis (ANOVA) and multiple linear regression model (p<0.05) were used. Results: the older adults who lived only with their spouses had better quality of life scores in all domains and facets, except in the death and dying domain, which did not show any significant difference. The lowest scores for quality of life were identified in the groups with the presence of children and, exceptionally, in the domain of social relationships and, in the facets death and dying and intimacy, those who lived alone had worse assessments. In the adjusted model, there was an association between the type of living arrangement and the different domains and facets of quality of life. Conclusion: living arrangement was associated with quality of life scores for older adults in the community, even after adjusting for the gender, age, number of morbidities, and social support variables.

scholarly journals Quality of life and symptom assessment in paraesophageal hernias: a systematic literature review of reporting standards

2021 ◽  
Vol 34 (7) ◽  
Author(s):  
Nikhil M Patel ◽  
Aiysha Puri ◽  
Viknesh Sounderajah ◽  
Lorenzo Ferri ◽  
Ewen Griffiths ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Literature Review ◽  
Systematic Literature Review ◽  
Symptom Severity ◽  
Assessment Tool ◽  
Assessment Tools ◽  
Life Questionnaire ◽  
Reporting Standards ◽  
Gi Symptoms

Summary Background Paraesophageal hernias (PEH) present with a range of symptoms affecting physical and mental health. This systematic review aims to assess the quality of reporting standards for patients with PEH, identify the most frequently used quality of life (QOL) and symptom severity assessment tools in PEH and to ascertain additional symptoms reported by these patients not captured by these tools. Methods A systematic literature review according to PRISMA protocols was carried out following a literature search of MEDLINE, Embase and Cochrane databases for studies published between January 1960 and May 2020. Published abstracts from conference proceedings were included. Data on QOL tools used and reported symptoms were extracted. Results This review included 220 studies reporting on 28 353 patients. A total of 46 different QOL and symptom severity tools were used across all studies, and 89 different symptoms were reported. The most frequently utilized QOL tool was the Gastro-Esophageal Reflux Disease-Health related quality of life questionnaire symptom severity instrument (47.7%), 57.2% of studies utilized more than 2 QOL tools and ‘dysphagia’ was the most frequently reported symptom, in 55.0% of studies. Notably, respiratory and cardiovascular symptoms, although less common than GI symptoms, were reported and included ‘dyspnea’ reported in 35 studies (15.9%). Conclusions There lacks a QOL assessment tool that captures the range of symptoms associated with PEH. Reporting standards for this cohort must be improved to compare patient outcomes before and after surgery. Further investigations must seek to develop a PEH specific tool, that encompasses the relative importance of symptoms when considering surgical intervention and assessing symptomatic improvement following surgery.

scholarly journals The effect of continuous care model on sleep quality in patients with multiple sclerosis

2021 ◽  
Vol 26 (1) ◽  
pp. 163-168
Author(s):  
Maedeh Pourhossein Alamdari ◽  
Fazlollah Ahmadi ◽  
Mahmoud Abedini
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Sleep Quality ◽  
Repeated Measures ◽  
Evaluation Model ◽  
Care Model ◽  
Chi Square ◽  
Continuous Care ◽  
Significant Difference

Multiple sclerosis is a chronic and unpredictable disease and is a growing trend and, like other chronic diseases, affects one's quality of life and since sleep quality is one of the dimensions of quality of life, this study aimed to investigate the effect of applying continuous care model on sleep quality of patients with MS in 2013. This clinical trial study was performed on 80 patients with multiple sclerosis who were randomly assigned to experimental and control groups. Data collection tools included demographic information questionnaire, PSQI questionnaire and model implementation in four stages (familiarization, sensitization, control, evaluation). Model stages were performed individually and in groups for three weeks according to patients' educational needs (sleep, activity, medication and nutrition) and after two months follow up, control and evaluation were performed. Data were analyzed using Chi-square test, independent t-test and repeated measures ANOVA and spss16 software. Statistical analysis of variance (ANOVA) with repeated measures showed a significant difference between the mean of total score and the scores of sleep quality dimensions in three times between the two groups (p<0.05). It can be concluded that the implementation of continuous care model causes a significant difference in the sleep quality of patients with MS.

scholarly journals School-based diabetes interventions and their outcomes: a systematic literature review

2015 ◽  
Vol 4 (1) ◽  
Author(s):  
Bénédicte Pansier ◽  
Peter J. Schulz
Keyword(s):  
Quality Of Life ◽  
Academic Performance ◽  
School Environment ◽  
Diabetes Management ◽  
School Personnel ◽  
Poor Quality ◽  
Assessment Tools ◽  
Significant Difference ◽  
Diabetes Interventions

Type 1 diabetes is one of the most common chronic childhood diseases, while type 2 diabetes in children is increasing at alarming rates globally. Against this backdrop, the school is a critical environment for children with diabetes. They continue to face barriers to education that may lead to depression, poor academic performance, and poor quality of life. To address these challenges, diabetes interventions have been implemented in school and the goal was to systematically review these interventions and their outcomes between 2000 and 2013. Fifteen studies were included in the narrative synthesis. Education of school personnel was the main focus before 2006. Studies reported gains in knowledge and perceived confidence of school staff. Since 2006, more comprehensive interventions have been developed to promote better care coordination and create a safe school environment. These studies reported improved diabetes management and quality of life of students. Assessment tools varied and study design included randomized controlled trials, quantitative and qualitative methods. Although many of the studies reported a significant difference in the parameters measured, it was not possible to determine optimal ways to improve the health, quality of life and academic performance of children with diabetes, given the disparity in scope, assessment tools and measured outcomes. Experimental designs, longer follow-up studies, larger sample sizes, and a higher number of participating schools are critical issues to consider in future studies. Most of the research was conducted in North America and further research is needed in other parts of the world.

scholarly journals The effect of concomitant fibromyalgia in HIV infected patients receiving antiretroviral therapy: a prospective cross-sectional study

2019 ◽  
Vol 18 (1) ◽  
Author(s):  
Umit Secil Demirdal ◽  
Neriman Bilir ◽  
Tuna Demirdal
Keyword(s):  
Quality Of Life ◽  
Antiretroviral Therapy ◽  
T Lymphocyte ◽  
Musculoskeletal System ◽  
Lymphocyte Count ◽  
Fibromyalgia Impact Questionnaire ◽  
Cross Sectional ◽  
Sf 36 ◽  
Significant Difference

Abstract Background HIV infected patients receiving antiretroviral therapy (ART) have extensive musculoskeletal system involvement. Arthralgia and myalgia are the most common forms. Fibromyalgia Syndrome (FMS) is a chronic pain syndrome of the musculoskeletal system characterized by diffuse pain including arthralgia and myalgia. These overlapping symptoms are suggested the relationship between HIV and FMS. The primary purpose of this study was to determine the prevalence of FMS in HIV/AIDS patients. The secondary objective was to investigate the effects of FMS on functional status, depression, fatigue, sleep pattern and quality of life. Methods A total of 225 HIV infected patients who were receiving ART were included in this cross-sectional prospective study. The demographic data of the participants, CD4 T-lymphocyte count (cells/mm3), viral load (> 40 copy/ml), and ART regimens were recorded. FMS diagnosis was based on 2016 revision of diagnostic criteria. All patients completed the following questionnaires: Fibromyalgia Impact Questionnaire (FIQ), Beck Depression Inventory (BDI), Pittsburgh Sleep Quality Index (PSQI), Fatigue Severity Scale (FSS), and SF-36 scale. Results FMS was found in 20% of the HIV infected patients (n = 45). The mean duration of disease was 4.74 ± 4.42 years; it was significantly longer in patients with FMS (p = 0.007). The median CD4 T-lymphocyte count was found to be 616.00 ± 303.91 cells/mm3, and it was significantly higher in patients without FMS (p = 0.06). No statistically significant difference was found between the two groups according to the drug regimens used. A statistically significant difference was found in FIQ, BDI, PSQI, FSS and all subgroups of the SF-36 scale between the patients with and without FMS (p = 0.001). Conclusions A slightly higher frequency of FMS was determined in HIV infected patients receiving ART compared to previous studies. It was shown that presence of FMS negatively affected the function, depression, fatigue, sleep, and quality of life. Detection of FMS may decrease depression, fatigue, and sleep disorders and increase the quality of life in HIV infected patients. FMS should be distinguished correctly for an accurate treatment management of HIV and for increasing ART compliance.

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