Lifestyle Changes Key To Metabolic Syndrome

2008 ◽  
Vol 38 (1) ◽  
pp. 17
Author(s):  
MIRIAM E. TUCKER
Keyword(s):  
Metabolic Syndrome ◽  
Lifestyle Changes

scholarly journals The effect of physical exercise and caloric restriction on the components of metabolic syndrome

2009 ◽  
Vol 45 (3) ◽  
pp. 379-399 ◽  
Author(s):  
Francisco Leonardo Torres-Leal ◽  
Mariana Dutilh de Capitani ◽  
Julio Tirapegui
Keyword(s):  
Metabolic Syndrome ◽  
Physical Exercise ◽  
Caloric Restriction ◽  
Epidemiologic Studies ◽  
Lifestyle Changes ◽  
Moderate Intensity ◽  
Mass Reduction ◽  
Current State ◽  
Regular Physical Exercise

Recent studies of the effects of physical exercise and caloric restriction have found several benefits on the metabolic and cardiovascular risk factors related to metabolic syndrome (MS). This review examines the current state of knowledge of the effects of physical exercise on the main pathologies associated with MS: obesity, insulin resistance, type 2 diabetes mellitus (DM2), dyslipidemias and hypertension. Although there are only a few randomized and controlled studies that evaluated the prevention and treatment of MS, strong evidence from controlled studies indicates that lifestyle changes that include regular physical exercise and caloric restriction are effective in preventing and treating DM2 in overweight individuals with reduced glucose tolerance. Likewise, epidemiologic studies suggest that regular physical exercise prevents the development of DM2 and cardiovascular disease. Based on current recommendations, it is important to increase the level of physical exercise at a moderate intensity to achieve good cardiorespiratory and muscular conditions and to promote fat mass reduction, with consequent reductions of risk of developing metabolic syndrome.

scholarly journals The Role of Bioactive Compounds from Dietary Spices in the Management of Metabolic Syndrome: An Overview

Nutrients ◽  
2021 ◽  
Vol 14 (1) ◽  
pp. 175
Author(s):  
Dana Hasan Alkhatib ◽  
Abdul Jaleel ◽  
Maryam Naveed Muhammad Tariq ◽  
Jack Feehan ◽  
Vasso Apostolopoulos ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Blood Glucose ◽  
Dietary Supplements ◽  
Bioactive Compounds ◽  
Fasting Blood Glucose ◽  
Density Lipoprotein ◽  
Preventive Measure ◽  
Blood Lipid ◽  
Lifestyle Changes

Metabolic syndrome (MetS) is a combination of physiologically dysregulated parameters that can include elevated fasting blood glucose, high blood pressure, central obesity, increased triglyceride levels, insulin resistance, diabetes, elevated low density lipoprotein levels, and reduced high density lipoprotein levels in the blood. Effective clinical management of MetS is critical as it is strongly associated with long lasting and fatal complications in patients. Alongside standard care of lifestyle changes and medication, dietary supplements derived from herbal resources could be an alternative therapeutic strategy that is safe, efficient, culturally acceptable, and has few side effects. Of the dietary supplements, spicy foods have always been considered a great source of functional bioactive compounds. Herbal therapy is broadly used in many countries as a treatment or as a preventive measure in the management of MetS risk factors, including blood glucose, blood pressure, and blood lipid levels. Herein, an attempt is made to evaluate the recent studies in the management of MetS with herbal alternatives, and to explore the possibility of their use as therapeutic treatments or supplements.

scholarly journals Non-alcoholic fatty liver disease and metabolic syndrome in childhood

2020 ◽  
Vol 183 (11) ◽  
pp. 51-61
Author(s):  
N. N. Vlasov ◽  
E. A. Kornienko
Keyword(s):  
Metabolic Syndrome ◽  
Liver Disease ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Lifestyle Changes ◽  
Alcoholic Fatty Liver ◽  
Ample Evidence ◽  
Alcoholic Fatty Liver Disease

There is ample evidence that insulin resistance, hyperinsulinemia, and obesity are at the heart of the development of non-alcoholic fatty liver disease (NAFLD). The disease is now considered as the hepatic component of metabolic syndrome (MS).64 children with NAFLD were assessed for metabolic syndrome stigma. An analysis was also made on the state of the problem according to the literature on the general links of the pathogenesis of these conditions, methods of diagnosis and treatment of NAFLD.All components of MS are observed with different frequencies in patients with NAFD. This disease, together with type 2 diabetes mellitus, becomes very common diseases in childhood. The incidence of NAFLD in children is constantly growing, it has begun to occur in infants, an outcome in cirrhosis of the liver is possible within childhood, although the prognosis for NAFLD remains definitely uncertain. Weight loss with a low glycemic index diet, regular exercise, and other lifestyle changes are the mainstay of NAFLD treatment, but not yet very effective for various reasons. In these conditions, it is necessary to increase the role of primary prevention of MS and NAFLD.

scholarly journals Metabolic side effects of clozapine in patients at south ceredigion community mental health team

BJPsych Open ◽  
2021 ◽  
Vol 7 (S1) ◽  
pp. S345-S345
Author(s):  
Harish Reddy
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Side Effects ◽  
Nutritional Intervention ◽  
Serum Glucose ◽  
Lifestyle Changes ◽  
Glucose Levels ◽  
Fasting Level ◽  
Waist Size ◽  
Patients At Risk

AimsThe aim of the audit was to identify patients at risk of developing Metabolic Syndrome who are on Clozapine in the community. Anyone who has three of following attributes has Metabolic Syndrome. A large waist size (greater than 40 inches in men or 35 inches in women) ,high blood pressure (130/85 mm Hg or higher) ,high triglycerides — a form of fat in the blood (150 mg/dL or higher) ,high blood sugar (a fasting level of 100 mg/dL or higher).Patients receiving should be regularly monitored under clinical review particularly in relation to side effects of the drug and maintain minimum standards of review both physically and clinical investigations once a year .BackgroundTo measure the screening of central obesity, Blood Pressure, serum glucose levels and lipid profile in last one year.MethodData were collected from Blood results and electronic entries of patients who are on Clozapine in South Ceredigion Community Mental Team. There were 31 patients of which 20 were male and 11 were female patients. The age range was 31–66 years and average was 46 years.Result52% of the patients had obesity,34 % with Hypertension,50 %Dyslipidaemia and 43 % had Increased glucose tolerance. 80 % were only on clozapine,3% were on combined Amisulpride, 10% on combined on Ariprazole, 3 % on combined Quetiapine.ConclusionTreatment of causes like making changing lifestyle changes, weigh reduction using health diet and to include regular physical activity. Reduce Abdominal Obesity and in possible provide nutritional intervention.

Physical activity and the metabolic syndrome in Canada

2006 ◽  
Vol 31 (1) ◽  
pp. 40-47 ◽  
Author(s):  
Susan E Brien ◽  
Peter T Katzmarzyk
Keyword(s):  
Physical Activity ◽  
Metabolic Syndrome ◽  
Health Surveys ◽  
Lifestyle Changes ◽  
Heart Health ◽  
Physically Active ◽  
The Metabolic Syndrome ◽  
Strenuous Activity ◽  
Therapeutic Lifestyle Changes ◽  
The Relationship

The metabolic syndrome (MetS) is a cluster of risk factors that predispose individuals to cardiovascular disease. Therapeutic lifestyle changes, including increased physical activity, are recommended for the prevention and treatment of MetS. The purpose of this study was to examine the relationship between physical activity and MetS in Canada. The sample included 6406 men and 6475 women aged 18-64 y who were participants in the Canadian Heart Health Surveys (1986-1992). MetS was classified using criteria modified from the US National Cholesterol Education Program. Participants were deemed physically active if they were active at least once each week for at least 30 min, engaging in strenuous activity some of the time. The relationship between physical activity and MetS was assessed using logistic regression, with age, smoking, alcohol consumption, and income adequacy as covariates. A total of 14.4% of Canadians had MetS and 33.6% were physically active. The odds ratio for MetS was 0.73 (95% confidence interval (CI): 0.54-0.98; p < 0.05) for physically active vs. physically inactive participants. The corresponding odds ratios were 0.45 (95% CI: 0.29-0.69; p < 0.001) and 0.67 (95% CI: 0.44-1.02; p = 0.06) for men and women, respectively. In summary, physical activity was associated with lower odds of MetS, particularly in men. Further research is required to determine the effectiveness of physical activity in the treatment of MetS.Key words: metabolic syndrome, physical activity, Canadian Heart Health Surveys.

scholarly journals Assessment of Metformin as an Additional Treatment to Therapeutic Lifestyle Changes in Pediatric Patients with Metabolic Syndrome

Cholesterol ◽  
2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Rebecca M. Raub ◽  
Stanley J. Goldberg
Keyword(s):  
Metabolic Syndrome ◽  
Pediatric Population ◽  
Additional Treatment ◽  
Lifestyle Changes ◽  
Control Group ◽  
Average Dose ◽  
Z Score ◽  
Positive Direction ◽  
Metformin Group ◽  
Therapeutic Lifestyle Changes

Objective. To assess the effectiveness of metformin and therapeutic lifestyle changes (TLCs) in a clinical setting, compared to TLC alone in adolescents with metabolic syndrome (MS). Methodology. This study was a retrospective trial consisting of 60 patients, aged 8–18 years, who were treated for MS at an outpatient clinic. Two groups were formed: the metformin group (M group) and the control group (C group). The M group had been given metformin along with TLC, and the C group had been given TLC alone. Several outcome measures were obtained; the main outcome measure was measuring the change in percentile and z-score of weight and BMI. Results. There were no significant differences between the two groups at the conclusion of the study, except for height percentile (P=0.02) and z-score (P=0.03). Both groups showed promising significant intragroup decreases in weight z-score but BMI percentile and z-score were only significantly decreased in the M group. Conclusion. Metformin at an average dose of 1033 mg, when added to TLC, did not show any clinically important efficacy compared to TLC alone in a pediatric population with MS. However, both groups made significant changes in a positive direction, which may be solely due to TLC.

scholarly journals Prospects for the Primary Prevention of Myocardial Infarction and Stroke

2018 ◽  
Vol 24 (3) ◽  
pp. 207-214 ◽  
Author(s):  
Madison Caldwell ◽  
Lisa Martinez ◽  
Jennifer G. Foster ◽  
Dawn Sherling ◽  
Charles H. Hennekens
Keyword(s):  
United States ◽  
Myocardial Infarction ◽  
Insulin Resistance ◽  
Metabolic Syndrome ◽  
Primary Prevention ◽  
Clinical Manifestations ◽  
The United States ◽  
Overweight And Obesity ◽  
Lifestyle Changes ◽  
Prevention And Treatment

Cardiovascular disease (CVD), principally myocardial infarction (MI) and stroke, is the leading clinical and public health problem in the United States and is rapidly becoming so worldwide. Their primary prevention is promising, in theory, but difficult to achieve in practice. The principal modalities that have demonstrated efficacy include therapeutic lifestyle changes (TLCs) and adjunctive drug therapies under the guidance of the health-care provider and tailored to the individual patient. The prevention and treatment of the pandemic of overweight and obesity and lack of regular physical activity, both of which are alarmingly common in the United States, prevention and treatment of hypertension, avoidance and cessation of cigarette smoking, adoption and maintenance of a healthy diet, and avoidance of heavy alcohol consumption all have proven benefits in decreasing the risks of a first MI and stroke as well as other clinical manifestations of CVD. Although adoption of TLCs would avoid the need for adjunctive drug therapies in many primary prevention subjects, this strategy is difficult to achieve or maintain for most and may be insufficient for many, especially those at high risk with metabolic syndrome. The criteria for metabolic syndrome, affecting over 40% of the adult population older than 40 in the United States, include overweight or obesity, dyslipidemia, hypertension, and insulin resistance, a precursor of diabetes. The adjunctive therapies of proven benefit in the primary prevention of MI and stroke include statins, blood pressure medications, aspirin, and drugs to treat insulin resistance and hyperglycemia. Fortunately, even for patients who prefer prescription of pills to proscription of harmful lifestyles, these drug therapies still have net benefits. The adoption and maintenance of TLCs and adjunctive drug therapies into clinical practice will reduce both the incidence of and mortality from a first MI and stroke as well as other major clinical manifestations of CVD.

scholarly journals Prevalence of Metabolic Syndrome and of Cardiovascular Risk Factors

2018 ◽  
Vol 15 (5) ◽  
pp. 35-42
Author(s):  
Manta Andrei ◽  
Maștaleru Alexandra ◽  
Oancea Andra ◽  
Anghel Razvan Constantin ◽  
Roca Mihai ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Public Health Problem ◽  
Left Ventricular ◽  
Lifestyle Changes ◽  
Therapeutic Success ◽  
The Metabolic Syndrome ◽  
Group 2 ◽  
Group 1

AbstractObesity, a component of the metabolic syndrome, is a rising public health problem, continuously increasing in the European countries. The therapeutic success of the patient with metabolic syndrome requires a multidisciplinary approach to lifestyle changes, weight loss, continuous and dynamic dietary improvement, sedentary reduction, normalization of blood pressure, glycemia and lipid parameters. We performed a retrospective study that was conducted in the Clinical Rehabilitation Hospital in Iasi, with 4627 patients that were admitted in the Cardiovascular Rehabilitation Clinic from January 2011 to December 2015 with the diagnosis of metabolic syndrome according to WHO definition (Group 1) or with other comorbidities (Group 2). In the first group were included 1064 patients diagnosed with metabolic syndrome. This group has predominantly smoking female patients. Also, in group 1 were diagnosed more patients with left ventricular hypertrophy and coronary heart disease compared to group 2. Most of the patients with inflammatory syndrome were included in the group without metabolic syndrome (group 2). The results of our study confirm that metabolic syndrome is a cluster of abnormalities whose evolution determines the development of coronary heart disease. All this would advocate for treating metabolic syndrome as the primary method of preventing cardiovascular disease.

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