scholarly journals Using the payback framework to evaluate the outcomes of pilot projects supported by the Georgia Clinical and Translational Science Alliance

Author(s):  
Latrice Rollins ◽  
Nicole Llewellyn ◽  
Manzi Ngaiza ◽  
Eric Nehl ◽  
Dorothy R. Carter ◽  
...  

Abstract Introduction: The Clinical and Translational Science Awards (CTSA) program of the National Center for Advancing Translational Sciences (NCATS) seeks to improve population health by accelerating the translation of scientific discoveries in the laboratory and clinic into practices for the community. CTSAs achieve this goal, in part, through their pilot project programs that fund promising early career investigators and innovative early-stage research projects across the translational research spectrum. However, there have been few reports on individual pilot projects and their impacts on the investigators who receive them and no studies on the long-term impact and outcomes of pilot projects. Methods: The Georgia CTSA funded 183 pilot projects from 2007 to 2015. We used a structured evaluation framework, the payback framework, to document the outcomes of 16 purposefully-selected pilot projects supported by the Georgia CTSA. We used a case study approach including bibliometric analyses of publications associated with the selected projects, document review, and investigator interviews. Results: These pilot projects had positive impact based on outcomes in five “payback categories”: (1) knowledge; (2) research targeting, capacity building, and absorption; (3) policy and product development; (4) health benefits; and (5) broader economic benefits. Conclusions: Results could inform our understanding of the diversity and breadth of outcomes resulting from Georgia CTSA-supported research and provide a framework for evaluating long-term pilot project outcomes across CTSAs.

2018 ◽  
Vol 2 (S1) ◽  
pp. 78-79
Author(s):  
Latrice Rollins ◽  
Nicole Llewellyn ◽  
Eric Nehl ◽  
Astrid Sosa

OBJECTIVES/SPECIFIC AIMS: We will use a structured evaluation framework, the payback framework, to document the outcomes of 15 case studies of pilot projects supported by Georgia CTSA from 2007 to 2014. METHODS/STUDY POPULATION: We will use a case study approach including bibliometric analyses of publications associated with the selected projects, document review (e.g., investigator curriculum vitae, biannual project reports) and investigator interviews. RESULTS/ANTICIPATED RESULTS: We will document outcomes in 5 “payback categories”: (1) knowledge, (2) research targeting, capacity building, and absorption, (3) policy and product development, (4) health benefits, and (5) broader economic benefits. DISCUSSION/SIGNIFICANCE OF IMPACT: This study will aid in characterizing the returns resulting from this research funding and identify its strengths and weaknesses. This study will inform our understanding of the diversity and breadth of outcomes resulting from Georgia CTSA-supported research, and the value pilot projects provide to clinical and translational science and the broader community.


2021 ◽  
Author(s):  
Bohuslav Slánský ◽  
Vit Šmilauer ◽  
Jiří Hlavatý ◽  
Richard Dvořák

A jointed plain concrete pavement represents a reliable, historically proven technical solution for highly loaded roads, highways, airports and other industrial surfaces. Excellent resistance to permanent deformations (rutting) and also durability and maintenance costs play key roles in assessing the economic benefits, rehabilitation plans, traffic closures, consumption and recycling of materials. In the history of concrete pavement construction, slow-to-normal hardening Portland cement was used in Czechoslovakia during the 1970s-1980s. The pavements are being replaced after 40-50 years of service, mostly due to vertical slab displacements due to missing dowel bars. However, pavements built after 1996 used rapid hardening cements, resulting in long-term surface cracking and decreased durability. In order to build durable concrete pavements, slower hardening slag-blended binders were designed and tested in the restrained ring shrinkage test and in isothermal calorimetry. Corresponding concretes were tested mainly for the compressive/tensile strength evolution and deicing salt-frost scaling to meet current specifications. The pilot project was executed on a 14 km highway, where a unique temperature-strain monitoring system was installed to provide long-term data from the concrete pavement. A thermo-mechanical coupled model served for data validation, showing a beneficial role of slower hydration kinetics. Continuous monitoring interim results at 24 months have revealed small curling induced by drying and the overall small differential shrinkage of the slab.


Author(s):  
Kelli Qua ◽  
Clara M. Pelfrey

Abstract Introduction: Evaluating clinical and translational research (CTR) mentored training programs is challenging because no two programs are alike. Careful selection of appropriate metrics is required to make valid comparisons between individuals and between programs. The KL2 program provides mentored-training for early-stage CTR investigators. Clinical and Translational Awards across the country have unique KL2 programs. The evaluation of KL2 programs has begun to incorporate bibliometrics to measure KL2 scholar and program impact. Methods: This study investigated demographic differences in bibliometric performance and post-K award funding of KL2 scholars and compared the bibliometric performance and post-K award federal funding of KL2 scholars and other mentored-K awardees at the same institution. Data for this study included SciVal and iCite bibliometrics and National Institutions of Health RePORTER grant information for mentored-K awardees (K08, K23, and KL2) at Case Western Reserve University between 2005 and 2013. Results: Results showed no demographics differences within the KL2 program scholars. Bibliometric differences between KL2 and other mentored-K awardee indicated an initial KL2 advantage for the number of publications at 5 years’ post-matriculation (i.e., the start of the K award). Regression analyses indicated the number of initial publications was a significant predictor of federal grant funding at the same time point. Analysis beyond the 5-year post-matriculation point did not result in a sustained, significant KL2 advantage. Conclusions: Factors that contributed to the grant funding advantage need to be determined. Additionally, differences between translational and clinical bibliometrics must be interpreted with caution, and appropriate metrics for translational science must be established.


2021 ◽  
Vol 21 (2) ◽  
pp. 97-117
Author(s):  
Marija Radulović ◽  
Milan Kostić

Abstract Research background: Economic relations between countries members of the EU and EU candidates are very strong. Germany and France have the leading economies of the EU, are in the top ten economies worldwide, and drivers of EU development. Serbia has strong economic relations with Germany and France, especially with Germany. Therefore, it is necessary to examine whether Germany and France impact the development of Serbia. Purpose: The purpose of the study is to determine if there is a positive influence of a developed country on a developing country. The aim of the paper is to determine whether there is a long- and short-term positive relationship between Germany and France (EU members) and the Serbian economy (EU candidate). Research methodology: A Vector Error Correction Model is used to analyze quarterly data from 2002Q2 to 2018Q2. Results: The results showed a statistically significant long-term relationship between Germany and France and Serbia’s real GDPs, so EU members have a long-term positive impact on the economy of EU candidates. In the case of the French, there is a short-run positive impact on the Serbian economy. For Germany, it is not the case. Novelty: This paper fills the literature gap about the influence of a developed country on a developing country. Recommendations for policymakers in EU candidates could be that if they want to motivate people to accept the process of access to the EU, they must provide them with more information about long-run economic benefits from the association to the EU.


Agriculture ◽  
2022 ◽  
Vol 12 (1) ◽  
pp. 99
Author(s):  
Chun Yang ◽  
Xuqi Chen

Since the outbreak of the COVID-19 pandemic, global food production and transportation have been largely impacted. Meanwhile, consumers have purchased and stockpiled large quantities of foods due to panic in the early stage of the pandemic, which has resulted in a lot of uneaten, expired foods and has reduced the varieties of foods available in the markets. Due to the lower prices, some consumers have chosen to buy those foods with an earlier production time or inferior quality (suboptimal foods), and the purchase rate of suboptimal foods has increased. Therefore, this study investigated consumer behavior during the pandemic as the research focus, explored the main dimensions that affect consumers’ purchasing of suboptimal foods during the COVID-19 pandemic, tested their correlations, and proposed suggestions for improvement. The results of this study showed that the impacts of Perceived Benefits on Attitude Toward Behavior, Perceived Behavioral Control, and Subject Norm rank 1st, 2nd, and 3rd in importance, respectively, which are all higher than the related impact of Environmental Concerns. For consumers, the most important thing is whether suboptimal foods have consumption motivation for them, which is also the most direct way to make consumers feel the value of suboptimal foods. Furthermore, for consumers, while the environmentally friendly attributes of suboptimal foods are less perceptible than the economic motivations, they still have considerable influence on consumers, and this is even more prominent during the COVID-19 pandemic. Many families have experienced a shock to their income during the pandemic, and consumers are more sensitive and concerned about commodity prices, which also makes lower-priced and more abundant suboptimal foods more popular. However, in the long term, suboptimal foods can have a positive impact on reducing food waste and protecting the environment. When consumers realize this, they will be more motivated to purchase and try suboptimal foods.


2017 ◽  
Vol 8 (4) ◽  
pp. 16
Author(s):  
Ra’ed Masa’deh ◽  
Mohammed Abdullah Nasseef ◽  
Mohammd Suliman ◽  
Monther Albawab

This study aims to examine the impact of hotel development (using the variables of positive social and cultural impacts, negative cultural & economic impacts, negative social impacts, community centered economic benefits, positive environmental impacts, government’s environment management, positive economic impacts, long-term planning, community development & involvement, amenities development & quality tourism experiences, and local prices & tax revenue) on sustainable tourism development at Aqaba hotels located in Jordan. A total of 170 questionnaire containing 44 items was used to collect information from the respondents. Simple regression, T-test, and ANOVA analyses were conducted to test the research hypotheses. Results of the current study revealed that there is a significant positive impact of hotel development on sustainable tourism development. Also, the results revealed that there is no significant difference in the impact of hotel development on sustainable tourism development that can be attributed to gender. Also, results indicated that there are no significant differences in the impact hotel development on sustainable tourism development in favor of age, educational level, personal income, work position, and hotel classification.


2021 ◽  
Vol 18 (04) ◽  
Author(s):  
Nicole Comfort

The United States (US) must strategically invest in diversifying its biomedical workforce to retain global leadership in biomedical research and to reduce racial and ethnic disparities in the US. The under-representation of minority groups in the biomedical sciences is influenced by the National Institutes of Health (NIH) grant funding process which relies heavily on peer review subject to bias. Despite recent initiatives to combat structural racism within the NIH, the NIH has done little to rectify racial disparities in funding allocation that have been known for over a decade. In this report, I evaluate current NIH proposals to reduce bias in peer review and present stronger policy options for reducing inequity in grant funding. I recommend that the NIH treat the race/ethnicity funding disparity as it did the early career investigator disparity and immediately relax paylines and simultaneously prioritize research topics that align with interests of under-represented investigators, while working to develop a modified lottery for grant funding as a long-term solution to the biases that can influence grant peer review. Policies to address disparities in grant funding will diversify the biomedical workforce and have a profound and long-term positive impact on providing equitable access to science careers, regardless of race.


2021 ◽  
Vol 8 ◽  
pp. 205435812110352
Author(s):  
M. Bevilacqua ◽  
S. Gradin ◽  
J. Williams ◽  
A. Romann ◽  
C. Lo ◽  
...  

Purpose: With evolving evidence around the progression, assessment, and management of autosomal dominant polycystic kidney disease (ADPKD), care of the disease has become increasingly complex. Needs assessments in British Columbia (BC) described variability in knowledge and comfort with incorporating these new aspects of ADPKD care into clinical practice. Undercapture of early-stage ADPKD patients in existing renal databases was also identified as an unmet need. Sources of Information: A multidisciplinary group of clinicians and patient partners with interest and expertise in ADPKD and/or multidisciplinary kidney care informed the project work. An existing provincial renal database was used to support the provincial ADPKD registry. Methods: A formalized, comprehensive provincial ADPKD Network was created within the existing infrastructure of multidisciplinary kidney clinics (MDCs) in BC. The Network is coordinated provincially and implemented locally. It incorporates robust data collection, education, creation, and dissemination of dedicated clinical tools; collaboration between clinics and clinicians across the province; and ongoing evaluation and continuous quality improvement. Key Findings: Over the 5 years since its inception, the BC ADPKD Network has enabled increased and earlier identification of British Columbians living with ADPKD and a shift in practice toward increased and earlier enrollment of ADPKD patients into MDCs. A host of tailored ADPKD clinical tools have been created and implemented in all MDCs across the province to support existing MDC staff in the delivery of more standardized and specialized ADPKD care. A collaborative provincial clinician network founded on Local Clinical Champions has been established to support ongoing experience sharing between clinics. An evaluation framework has been established to evaluate outcomes and enable ongoing refinement of the Network. Limitations: The provincial ADPKD registry is undergoing enhancements to enable more comprehensive capture of APDKD-specific information such as total kidney volume and genetic results, but at present, this remains a limitation. It remains to be seen whether the activities of the ADPKD Network will improve long-term clinical outcomes and care experiences of patients living with ADPKD, and a long-term sustainability assessment of this model of care will be required. Implications: The structure, tools, and coordinated and collaborative clinician network established through this comprehensive provincial ADPKD Network may be valuable in addressing the variability and gaps in existing ADPKD care while allowing patients and families across BC to receive enhanced care locally, in their usual kidney care environments.


Author(s):  
Yuliia Nehoda

The subject of the research – is a set of organizational-economic relations arising in the process of structural transformation of financial and credit relations in the agricultural business. The purpose of the article is a retrospective analysis of structural transformations of financial and credit relations in the agricultural business, evaluation of the effectiveness and feasibility of the introduction of agricultural receipts as a new instrument of lending to the agricultural business of the regions. Methodology of work – system-structural and comparative analyzes (to determine the effectiveness of the crediting mechanism according to the agricultural receipts of the farmers of the region); monographic (when studying the problems of the functioning of the mechanism of lending to agrarians by agrarian receipts) economic analysis (when carrying out a comparative analysis of the mechanism of classical bank lending to the agrarian business and the mechanism of lending to agrarians according to agrarian receipts); modeling and forecasting (when determining ways to overcome the existing deficiencies in the mechanism of lending to agrarian business entities of the region according to agrarian receipts). The results of the work – a retrospective analysis of the structural transformation of financial and credit relations in the agricultural business was carried out. The mechanism of crediting agrarians according to agrarian receipts and the scale of its distribution in the agrarian business of the region are considered. A comparative analysis of the mechanism of classical bank lending to the agrarian business and the mechanism of lending to agrarians according to agrarian receipts was carried out. In the framework of the pilot project “Agrarian receipts in Ukraine” of the international financial corporation (IFC) in partnership with the Swiss Confederation in Ukraine, the example of the Poltava region defined the effectiveness of the crediting mechanism according to the agrarian receipts of the agrarians of the region. The advantages and disadvantages of the mechanism of crediting the subjects of the agrarian business on agrarian receipts are noted. The ways to overcome the existing shortcomings of the mechanism of crediting the subjects of the agrarian business of the region according to agricultural receipts are determined. Conclusions – according to the results of the conducted research, the effectiveness of the mechanism of lending to the agricultural business of the regions according to agricultural receipts was proved, its advantages and disadvantages were noted, and attention was also focused. Proposed in Art. 7 of Law No. 5479-VI clearly delineate cases and restrictions on the debtor’s reimbursement of expenses incurred by the lender with the acquisition of the right to grow and harvest the pledged crop of agricultural products, which will ensure the principle of equality of parties on economic benefits and distribution of credit risks according to agricultural receipts.


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