scholarly journals Effect of bis(maltolato)oxovanadium (IV) (BMOV) on selenium nutritional status in diabetic streptozotocin rats

2011 ◽  
Vol 108 (5) ◽  
pp. 893-899 ◽  
Author(s):  
Cristina Sanchez-Gonzalez ◽  
Carmen Bermudez-Peña ◽  
Fernando Guerrero-Romero ◽  
Cristina E. Trenzado ◽  
María Montes-Bayon ◽  
...  

The role of V as a micronutrient, and its hypoglycaemic and toxicological activity, have yet to be completely established. The present study focuses on changes in the bioavailability and tissue distribution of Se in diabetic streptozotocin rats following treatment with V. The following four study groups were examined: control; diabetic (DM); diabetic treated with 1 mg V/d (DMV); diabetic treated with 3 mg V/d (DMVH). V was supplied in the drinking water as bis(maltolato)oxovanadium (IV). The experiment had a duration of 5 weeks. Se was measured in food, faeces, urine, serum, muscle, kidney, liver and spleen. Glucose and insulin serum were studied, together with glutathione peroxidase (GSH-Px), glutathione reductase (GR), glutathione transferase (GST) activity and malondialdehyde (MDA) levels in the liver. In the DM group, we recorded higher levels of food intake, Se absorbed, Se retained, Se content in the kidney, liver and spleen, GSH-Px and GST activity, in comparison with the control rats. In the DMV group, there was a significant decrease in food intake, Se absorbed, Se retained and Se content in the liver and spleen, and in GSH-Px and GST activity, while fasting glycaemia and MDA remained unchanged, in comparison with the DM group. In the DMVH group, there was a significant decrease in food intake, glycaemia, Se absorbed, Se retained, Se content in the kidney, liver and spleen, and in GSH-Px and GST activity, and increased MDA, in comparison with the DM and DMV groups. We conclude that under the experimental conditions described, the treatment with 3 mg V/d caused a tissue depletion of Se that compromised Se nutritional status and antioxidant defences in the tissues.

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Cristina Sánchez-González ◽  
Carlos López-Chaves ◽  
Cristina E. Trenzado ◽  
Pilar Aranda ◽  
María López-Jurado ◽  
...  

The role of vanadium as a micronutrient and hypoglycaemic agent has yet to be fully clarified. The present study was undertaken to investigate changes in the metabolism of iron and in antioxidant defences of diabetic STZ rats following treatment with vanadium. Four groups were examined: control; diabetic; diabetic treated with 1 mgV/day; and Diabetic treated with 3 mgV/day. The vanadium was supplied in drinking water as bis(maltolato) oxovanadium (IV) (BMOV). The experiment had a duration of five weeks. Iron was measured in food, faeces, urine, serum, muscle, kidney, liver, spleen, and femur. Superoxide dismutase, catalase, NAD(P)H: quinone-oxidoreductase-1 (NQO1) activity, and protein carbonyl group levels in the liver were determined. In the diabetic rats, higher levels of Fe absorbed, Fe content in kidney, muscle, and femur, and NQO1 activity were recorded, together with decreased catalase activity, in comparison with the control rats. In the rats treated with 3 mgV/day, there was a significant decrease in fasting glycaemia, Fe content in the liver, spleen, and heart, catalase activity, and levels of protein carbonyl groups in comparison with the diabetic group. In conclusion BMOV was a dose-dependent hypoglycaemic agent. Treatment with 3 mgV/day provoked increased Fe deposits in the tissues, which promoted a protein oxidative damage in the liver.


2019 ◽  
Vol 22 (11) ◽  
pp. 213-223
Author(s):  
Meirina Dwi Larasati ◽  
Nurul Dwi Anggriyani ◽  
Susi Tursilowati ◽  
Ria Ambarwati ◽  
Yuniarti Yuniarti

2020 ◽  
Vol 8 (2) ◽  
pp. 101-106
Author(s):  
Risky Amelia Rhamadani ◽  
Reny Noviasty ◽  
Ratno Adrianto

Background : Nutrition problems in toddlers become a public health problem when it exceeds WHO indicators in which the issue of malnutrition and undernutrition 17.8%, short toddlers 27.5% and thin toddlers 11.1%. The problem of undernutrition, short and thin toddlers are public health problem in the chronic category.Objective :  to determine the factor related to the nutritional status of toddlers in Loa Ipuh Health Centre. The design of this research is a cross-sectional study with total sample of 97 toddlers. Data collection uses anthropometric measurements, 24 hours of form food recall and questionnaires for mother's knowledge of breastfeeding complementary feeding and the utilization of health services.Method : Data analysis is using Pearson product-moment test with a significance level of 0.05. The results showed that there was a significant positive relationship between the food intake with the WAZ (P=0,000), HAZ (P=0,000) and  WHZ (P=0,021), mother's knowledge about complementary feeding with the WAZ (P=0,041), HAZ (P=0,010) and WHZ (P=0,010), utilization of health services with the WAZ (P=0,007), HAZ (P=0,009) and WHZ (P=0,006). Result : there is a significant positive relationship between intake of toddler feeding, mother's knowledge about complementary feeding and the utilization of health services with the nutritional status of toddlers WAZ, HAZ, and WHZ. Access to health services should be improved and evenly distributed throughout the health centre area.Conclusion : There is a significant positive relationship between food intake for children under five, maternal knowledge about complementary foods and health service utilization with the nutritional status 


2021 ◽  
Vol 5 (1) ◽  
pp. 41
Author(s):  
Inggita Kusumastuty ◽  
Dian Handayani ◽  
Harjoedi Adji Tjahjono ◽  
Elsa Permata Sari ◽  
Silvy Kartika Rahayuningtyas ◽  
...  

Background: Previous research state the correlation between vitamin D deficiency and Type 1 diabetes. The deficiency of Vitamin D is caused by vitamin D intake, sunlight exposure, or nutritional status. Indonesia, as a tropical country, is close to the equator and receives sunlight all year long. Little research has been done on vitamin D levels in children and adolescents with Type 1 Diabetes in Indonesia.Objective: The study aims to determine the relationship among sunlight exposure, nutritional status, food intake, and vitamin D levels in children and adolescents with Type 1 Diabetes.Methods: The study design was cross-sectional with a sample size of 31 children and adolescents aged 5-19 years. Sunlight exposure data were collected using the Sun Exposure Questionnaire form, nutritional status o BMI/age data were using the WHO Anthro, food intake data were using the Semi-Quantitative Food Frequency Questioner, and vitamin D level data were using the ELISA method. Statistical analysis was conducted by using SPSS Version 21 with Pearson and Spearman correlation test.Results: All respondents showed vitamin D deficiency. Most respondents had low sunlight exposure and nutritional status in the normoweight category. The majority of respondents had good energy and protein intake, excess fat, low carbohydrates, and low vitamin D and calcium.Conclusion:There is a positive relationship between sunlight exposure and vitamin D level (p = 0.001, r = 0.627). However, there is no relationship among nutritional status, protein intake, fat, carbohydrates, vitamin D and calcium on the level of vitamin D (p = 0.409; p = 0.240; p = 0.311; p = 0.822; p = 0.231; 0.382).


2021 ◽  
Vol 41 (1) ◽  
pp. 39-67
Author(s):  
Md Abdul Karim ◽  
Jesmin Akter

This study aims to investigate the determinants of nutritional status (BMI) of school girls, selected randomly from the schools of Chittagong metropolitan area because good nutritional status is a prerequisite for good health, fertility and national productivity. The results of this study show that more than one-third (38.6%) school girls belong to underweight, 47.9% normal and 13.5% overweight. The overall mean BMI of the selected girls is found 20.03±4.06 kg/m2 with considerable variations by their background characteristics. The co-efficient of variation (20.27%) indicates that there exists extreme heterogeneity in BMI of the respondents. Co-efficient of skewness (β1=0.85) and excess of kurtosis (γ2=1.05) reflect that the distribution of BMI is positively skewed and leptokurtic. The mean BMI is found relatively high among the respondents living in the metropolitan area (21.18 kg/m2). The highest mean BMI is found among the girls belong to high family income group (21.62 kg/m2) and low (18.69 kg/m2) in lower family income group. Bivariate analysis indicates that religion, place of origin, place of residence, respondents’ education, arm circumference, fathers and mothers education and occupation, family income, family size, sibling size, skipping and cycling, duration of sporting activity and sleeping, and food intake are found to have significant association with nutritional status of the girls. The study also shows that BMI is significantly positively correlated with family income and negatively with duration of sporting activities. Multinomial logistic regression analysis illustrates that place of residence, arm circumference, mothers’ occupation, duration of sleeping and food intake is found significant predictors of BMI. The Chittagong Univ. J. Sci. 40(1) : 39-67, 2019


1992 ◽  
Vol 12 (2) ◽  
pp. 223-233 ◽  
Author(s):  
N Battistini ◽  
D Caselli ◽  
G Bedogni ◽  
G Gatti

PEDIATRICS ◽  
1980 ◽  
Vol 66 (1) ◽  
pp. 156-157
Author(s):  
Robert P. Dillard

In their article, Shull et al1 imply that the mode of breast -feeding is causally related to the observed differences in growth velocity. They do this even though: (1) no food intake data were obtained on the breast fed infants; (2) type of supplemental feeding received by breast-fed infants older than 6 months was unknown; (3) maternal nutritional status while nursing was unknown; (4) measurements of the child's nutritional status other than growth velocity were not made; (5) dietary disparities appeared present within macrobiotic and nonmacrobiotic groups; (6) parental socioeconomic class was not evaluated.


PeerJ ◽  
2018 ◽  
Vol 6 ◽  
pp. e5935 ◽  
Author(s):  
Sanni Yaya ◽  
Ruoxi Wang ◽  
Shangfeng Tang ◽  
Bishwajit Ghose

Abstract There is little evidence on maternal consumption of supplementary food on nutritional status of children. The objectives of this study were to measure the prevalence and determinants of supplementary food intake during pregnancy and lactation, and their association with nutritional status of under-five children in Timor Leste. Methods Cross-sectional data from Timor Leste Demographic and Health Survey on 5,993 mother (15–49 years) child dyads (<5 years) were included in the analysis. Self-reported intake of supplementary food intake was the explanatory variable. Child’s nutritional status was assessed by stunting, wasting, and underweight and categorized according to WHO recommendations. Results The prevalence of taking supplementary food during pregnancy and lactation was, respectively, 29.1% (95% CI [27.2–31.0]) 31.0% (95% CI [29.1–33.0]), and that of taking iron supplement during pregnancy was close to three-fifths (63.1%, 95% CI [60.9–65.3]). The odds of taking supplementary food during pregnancy and lactation were lower among those in the younger age groups and higher among urban residents. Compared with mothers who had supplementary food during pregnancy and lactation, those did not have had respectively 1.36 (OR = 1.360, 95% CI [1.191–2.072]) and 1.15 times (OR = 1.152, 95% CI [1.019–1.754]) higher odds of having stunted, and 1.30 (OR = 1.307, 95% CI [1.108–1.853]) and 1.43 (OR = 1.426, 95% CI [1.140–1.863]) times higher odds of having underweight children. Those who had none of the supplements had respectively 1.67 (OR = 1.674, 95% CI [1.118–2.087]) and 1.63 (OR = 1.631, 95% CI [1.130–2.144]) times higher odds of having stunted and underweight children. Conclusion A great majority of the mothers in Timor Leste are not taking supplementary food during pregnancy and lactation. We found a positive relationship between supplementary food intake during pregnancy and lactation with stunting and wasting among under-five children.


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