scholarly journals Dietary and anthropometric indicators of nutritional status in relation to Helicobacter pylori infection in a paediatric population

2015 ◽  
Vol 113 (7) ◽  
pp. 1113-1119 ◽  
Author(s):  
Mariana A. Janjetic ◽  
Paula Mantero ◽  
Eduardo Cueto Rua ◽  
Norma Balcarce ◽  
Gerardo Zerbetto de Palma ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Nutritional Status ◽  
Dietary Intake ◽  
Age Groups ◽  
Gastrointestinal Symptoms ◽  
Paediatric Population ◽  
Overweight And Obesity ◽  
Dietary Recall ◽  
Anthropometric Indicators ◽  
H Pylori

It has been postulated that Helicobacter pylori infection could affect growth and appetite, consequently influencing body weight. Therefore, the association between H. pylori infection and the dietary and anthropometric indicators of nutritional status of a paediatric population were investigated. A total of 525 children (aged 4–16 years) who were referred to the gastroenterology unit of the Sor Maria Ludovica Children's Hospital from Buenos Aires, Argentina, were enrolled and completed an epidemiological questionnaire. H. pylori infection was diagnosed using the 13C-urea breath test (13C-UBT). Height and weight were assessed for calculation of anthropometric indicators. Energy and macronutrient intakes were estimated by 24 h dietary recall. Data analysis was performed using a χ2 test, a Student's t test, a Mann–Whitney U test and linear and logistic regressions. The prevalence of H. pylori infection was 25·1 % (with a mean age of 10·1 (sd 3·1) years). A tendency towards lower energy, carbohydrate, protein and fat intakes was observed in infected patients; however, it was not associated with H. pylori infection in any of the evaluated age groups (4–8, 9–13 and 14–16 years). Underweight, stunting, overweight and obesity were also not associated with the infection. Although height-for-age and BMI-for-age Z scores tended to be lower in infected patients, the differences between H. pylori-positive and H. pylori-negative children were not statistically significant. In conclusion, H. pylori infection was not associated with dietary intake or with anthropometric indicators in the present population of children with gastrointestinal symptoms; however, an increased sample size would be needed to confirm the observed tendency towards lower dietary intake and lower anthropometric indicators of nutritional status in H. pylori-infected children.

scholarly journals Specific Serum Immunoglobulin G Response to Urease and CagA Antigens of Helicobacter pylori in Infected Children and Adults in a Country with High Prevalence of Infection

2002 ◽  
Vol 9 (1) ◽  
pp. 97-100 ◽  
Author(s):  
Javier Torres ◽  
Margarita Camorlinga-Ponce ◽  
Guillermo Perez-Perez ◽  
Leopoldo Muñoz ◽  
Onofre Muñoz
Keyword(s):  
Helicobacter Pylori ◽  
Immunoglobulin G ◽  
Natural Infection ◽  
Age Groups ◽  
Gastrointestinal Symptoms ◽  
Enzyme Linked Immunosorbent Assay ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Serologic Response ◽  
H Pylori

ABSTRACT Few studies have analyzed the immune response to Helicobacter pylori CagA and urease antigens across age groups in the same population. The aim of this study was to analyze the serologic immunoglobulin G (IgG) response to CagA and urease proteins in children and adults with gastrointestinal symptoms and belonging to the same population and similar socioeconomic levels. The serologic response was studied in 352 children and 293 adults with gastrointestinal symptoms. IgG antibodies against CagA and urease were tested by enzyme-linked immunosorbent assay methods using highly purified recombinant antigens. H. pylori infection was defined as a positive result in a serologic assay using whole-cell H. pylori extracts as the antigen. We found, in H. pylori-positive children, a seroprevalence of 46.9% to CagA and 16.2% to urease, whereas in H. pylori-positive adults, a seroprevalence of 78.9% to CagA and 59% to urease was found. In children, the magnitude of the response to CagA was significantly higher and the response to urease was significantly lower than those in adults. The kinetics of serologic response to CagA and to urease across age groups was contrastably different. Whereas CagA is a strong immunogen, urease is a poor immunogen during natural infection. These differences in the humoral response may be important for the short-term or long-term outcome of the infection. These results add to our knowledge of the epidemiology of H. pylori infection.

Perfil Epidemiológico de Pacientes Submetidos à Biópsia Gástrica em um Hospital Escola do Sul de Minas Gerais/ Epidemiological Profile of Patients Undergo Gastric Biopsy in a School Hospital of Minas Gerais

1970 ◽  
Vol 4 (3) ◽  
pp. 48-57
Author(s):  
Isabela Maria A. Ribeiro Simões ◽  
Ana Carolina Mauad Coli ◽  
Roseane de Souza Candido Irulegui
Keyword(s):  
Helicobacter Pylori ◽  
Age Groups ◽  
Epidemiological Data ◽  
Minas Gerais ◽  
Gastric Biopsy ◽  
Gastric Ulcers ◽  
Histopathological Diagnosis ◽  
Gastric Diseases ◽  
H Pylori ◽  
Epidemiological Profile

Objetivo: Determinar a prevalência de lesões benignas e neoplasia gástrica através do estudo de biópsias realizadas em um Hospital Escola do Sul de Minas Gerais, no período entre 2007 e 2011. Materiais e Métodos: A pesquisa documental foi quantitativa e retrospectiva, baseada na análise dos registros de biópsias e prontuários. Realizou-se o levantamento de dados referentes à idade, gênero, cor, profissão, diagnóstico histopatológico e presença de Helicobacter pylori nas amostras. Resultados: O número total de biópsias gástricas analisadas foi de 1225, cujo perfil populacional encontrado foi: idade média de 56,75 anos, sexo masculino (52%), cor branca (81,9 %), aposentado (30%). Os diagnósticos mais frequentes foram: gastrites (71,9%), pólipos (14,2%), adenocarcinomas (5,9%), úlceras gástricas (6%), linfomas (0,4%), sem alterações (0,4%) e outros (1,2%). Em outros, encontram-se achados de malignidade, metaplasia e xantelasma gástrico. Em relação à presença de Helicobacter pylori nas amostras, o resultado encontrado foi de24% positivas, 46% negativas e 30% não pesquisadas. Conclusão: Os resultados confirmam a alta frequência das doenças gástricas e sua incidência nas diversas faixas etárias, além do envolvimento do H. pylori em tais afecções. É de grande importância a caracterização dos dados epidemiológicos, o que permite prováveis direcionamentos para programas de prevenção e informação para a população. Palavras-chave: biópsia gástrica, gastropatia, perfil epidemiológico.  ABSTRACTObjective: To determine the prevalence of benign lesions and gastric cancer through study of biopsies performed at a school hospital in southern Minas Gerais, in the period between 2007 and 2011.Materials and Methods: The research was quantitative and retrospective, based on analysis of biopsies records and medical records. We conducted the survey data regarding age, sex, color, profession, histopathological diagnosis and the presence of Helicobacter pylori in the samples. Results: The total number of gastric biopsies analyzed was 1225. Population listing was found: mean age of 56.75 years, male (52%), white (81.9%), retired (30%). The most frequent diagnoses were gastritis (71.9%), polyps (14.2%), adenocarcinomas (5.9%), gastric ulcers (6%), lymphoma (0.4%), unchanged (0, 4%) and others (1.2%). In others, there are: findings of malignancy, metaplasia, gastric xanthelasma. Regarding the presence of Helicobacter pylori in the sample, the result was: 24% positive, 46% negative, 30% non searched. Conclusion: The results confirm the high frequency of gastric diseases and their incidence in the various age groups additionally to the involvement of H. pylori in such conditions. It is of great importance to characterize the epidemiological data, allowing probable directions for prevention and information programs for population. Keywords: gastric biopsy, gastropathy, epidemiological profile

scholarly journals Evaluation of Helicobacter pylory colonization by serologic test (IgG) and dyspepsia in volunteers from the countryside of Monte Negro, in the Brazilian western Amazon region

2010 ◽  
Vol 52 (4) ◽  
pp. 203-206 ◽  
Author(s):  
Rafael Bernardon Ribeiro ◽  
Herlon Saraiva Martins ◽  
Vera Aparecida dos Santos ◽  
Marcelo el Khouri ◽  
Leandro Savoy Duarte ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Rural Areas ◽  
Age Groups ◽  
Developed Countries ◽  
Progressive Increase ◽  
Amazon Region ◽  
Statistical Association ◽  
Serologic Test ◽  
Positive Serology ◽  
H Pylori

The present study intended to analyze the seroprevalence of Helicobacter pylori, IgG, and its relation to dyspepsia in a population from the western Amazon region. During the "Projeto Bandeira Científica", a University of São Paulo Medical School program, in Monte Negro's rural areas, state of Rondônia, 266 blood samples were collected from volunteers. The material was tested for IgG antibodies anti-Helicobacter pylori by ELISA method and the participants were also interviewed on dyspepsia, hygiene and social aspects. Participants aged between five and 81 years old (34 years on average), 149 (56%) were female and 117 (44%) male. We found 210 (78.9%) positive, 50 (18.8%) negative and six (2.3%) undetermined samples. Dyspeptic complaints were found in 226 cases (85.2%). There was no statistical association between dyspepsia and positive serology for H. pylori. We concluded that the seroprevalence in all age categories is similar to results found in other studies conducted in developing countries, including those from Brazil. On the other hand, the seroprevalence found in Monte Negro was higher than that reported in developed countries. As expected, there was a progressive increase in the positivity for H. pylori in older age groups.

scholarly journals Characteristics of Helicobacter pylori infection in a National Referral Hospital in Bhutan

2020 ◽  
Vol 6 (1) ◽  
pp. 6-10
Author(s):  
Chhabi Lal Adhikari ◽  
Guru Prasad Dhakal ◽  
Nongluck Suwisith ◽  
Sonam Dargay ◽  
Krishna P Sharma
Keyword(s):  
Gastric Cancer ◽  
Helicobacter Pylori ◽  
Age Groups ◽  
Referral Hospital ◽  
Upper Gastrointestinal Endoscopy ◽  
Age Group ◽  
Exact Test ◽  
Significant Difference ◽  
H Pylori ◽  
National Referral Hospital

Introduction: Helicobacter pylori (H. pylori) is a bacterium causing chronic gastric infection and may cause gastric cancer. It was necessary to see the trend of infection, especially in symptomatic patients. This retrospective descriptive study was aimed to describe the characteristics of H. pylori infection in Bhutanese patients referred for an endoscopy to the National Referral Hospital, Thimphu. Methods: The sample of the study was randomized 380 medical records of the patients who underwent upper gastrointestinal endoscopy and Rapid Urea Test for symptomatic dyspepsia and peptic ulcer. Data was collected using a survey form designed by the researchers. Data analysis was done using descriptive statistics and either Chi-square or Fisher’s exact test. Results: The prevalence of H. pylori infection was very high (76.6%). The mean age of the infection was 42 with a range from 15 to 84 years. The highest prevalence of infection was observed in the age group 20-29 years (82.7%) and lowest in the oldest age group 70-84 years (66.7%). The analysis showed no significant difference in infection amongst age groups, gender, and endoscopic findings to the positive results at 5% significant level except for monthly prevalence (p<0.001). Gastritis was the commonest endoscopy finding (153/380) and gastro-duodenitis had the highest positivity rate (88.9%). Conclusion: The prevalence of infection was relatively high compared with previous studies. Young and middle-aged adults had a high prevalence and this group needs to be given priority for screening and eradication treatment considering limited resources to prevent associated gastric cancer in Bhutan.

scholarly journals Helicobacter pylori infection in Iran: demographic, endoscopic and pathological factors

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Seyedeh Amineh Hojati ◽  
Sara Kokabpeyk ◽  
Salma Yaghoubi ◽  
Farahnaz Joukar ◽  
Mehrnaz Asgharnezhad ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Peptic Ulcer ◽  
Epigastric Pain ◽  
Tap Water ◽  
Clinical Manifestations ◽  
Gastrointestinal Symptoms ◽  
Common Symptom ◽  
Pathological Findings ◽  
Significant Difference ◽  
H Pylori

Abstract Background Helicobacter pylori (H. pylori) infection is the most important risk factor for gastritis and peptic ulcer. However, factors other than H. pylori are involved in its pathogenesis. In the current study, we aimed to compare the clinical manifestations and endoscopic and histopathological findings of patients with and without H. pylori infection. Methods In this cross-sectional study, 233 patients with dyspepsia, referred for endoscopy, were examined regarding the presence of H. pylori infection. During an endoscopic exam, 5 biopsy specimens were taken from the stomach. The criteria for the presence of H. pylori infection was the presence and identification of bacteria in pathology. Two groups of H. pylori-positive and H. pylori-negative patients were compared regarding their demographic, endoscopic, and pathological findings. Results Of 233 patients, 154 (66.1%) were non-smokers, 201 (86.3%) were not alcohol users, and 153 (65.7%) used tap water. The most common symptom, reported in 157 (67.4%) patients, was epigastric pain. There was a significant difference between patients with and without H. pylori infection in terms of the educational status, occupational status, family history of gastrointestinal cancer, and some gastrointestinal symptoms. Also, there was a significant relationship between the endoscopic and pathological findings of patients with H. pylori. Conclusions The results of the present study revealed that H. pylori infection was not associated with sex, alcohol consumption, or non-steroidal anti-inflammatory drug use. The role of H. pylori in the pathophysiology of peptic ulcer was clarified. Also, there was a significant difference in the endoscopic and pathological findings of patients with H. pylori.

scholarly journals PO-085 Investigation and assessment of nutritional status among Chinese elite artistic swimming athletes

2018 ◽  
Vol 1 (3) ◽  
Author(s):  
Liang Li ◽  
Jianfang Xu ◽  
Huayu Fang ◽  
Xiaojing Wang
Keyword(s):  
Nutritional Status ◽  
Dietary Intake ◽  
Energy Intake ◽  
Nutritive Value ◽  
Female Athletes ◽  
Early Morning ◽  
Fat Percentage ◽  
Food Material ◽  
Dietary Recall ◽  
Waist Hip Ratio

Objective The sport of artistic swimming is unique which requires a mixture of endurance, power, acrobatics, flexibility, and eurhythmics to produce an artistic performance. Optimal nutrition plays an important role in attaining high level of achievements for artistic swimming athletes, a poor nutritional status will significantly affect their health, athletic performance and post-exercise recovery. However, the assessment of nutritional status among artistic swimming athletes is very lack. The purpose of present study was to assess the nutritional status of Chinese elite artistic swimming athletes and provide suggestions for them to modify their dietary structures. Methods During the summer training season before the 17th FINA World Championships, 17 Chinese elite artistic swimming female athletes participated in this study. After an overnight fast, the anthropometric data including height, weight, BMI, body fat percentage (BF%), and waist/hip ratio were collected in the early morning around 7 a.m. before breakfast. The 24 hours dietary recall was used to collect dietary intake data of individuals, the athletes were required to record their daily dietary intake in the structured questionnaire for 2 work days and 1 weekend day. During data processing, the cooked foods were converted into raw amounts of each food material by standardized recipe method, and the nutritive value was calculated by using a dietary nutrients analysis software. Results The athletes were 19.6±1.7 years old and their training age was 10-12 years. The athletes’ BMI was 18.3±1.4 kg/m2, their BF% and waist/hip ratio was 16.6±2.6% and 0.85±0.02 respectively. Even the athletes’ body composition level was in the normal range, the BMI and BF% were lower than Russia and Spain artistic swimming athletes. The daily energy intake was 1528±276 kcal which was composed of 435±50 kcal breakfast, 477±62 kcal lunch, 402±49 kcal supper, and 214±22 kcal snacks. However, the energy intake was much lower than the recommendation of 3500 kcal/day. Carbohydrates provided approximately 51% of total energy which was lower than the practical demands, but both fats and proteins provided more energy (31.3% and 17% respectively) than the recommendations. In addition, the supplementation of many important vitamins and minerals, except vitamin E and sodium, were not reached the recommended level, for example, the consumption of vitamin C and calcium was only 46±12 mg and 430±72 mg per day. Conclusions The data showed that the nutritional status was unsatisfactory among Chinese elite artistic swimming female athletes, the dietary energy intake and many important vitamins and minerals were much lower than the recommendations. In order to keep healthy and increase the exercise performance, it was suggested that the artistic swimming athletes should modify their dietary structures to supply more energies, vitamins and minerals according to their physical conditions and training arrangements.

scholarly journals Comparative analysis of genotypes of Helicobacter pylori strains in the Rostov and Astrakhan regions

2018 ◽  
Vol 9 (4) ◽  
pp. 81-86
Author(s):  
V. M. Sorokin ◽  
R. V. Pisanov ◽  
A. S Vodop’janov ◽  
E. V. Golubkina ◽  
E. A. Bereznjak
Keyword(s):  
Helicobacter Pylori ◽  
Peptic Ulcer ◽  
Comparative Analysis ◽  
Mucous Membrane ◽  
Adult Population ◽  
Age Groups ◽  
Biopsy Material ◽  
Pathogenicity Factors ◽  
Rostov Region ◽  
H Pylori

Objective:to study the infection of the adult and children’s population of the Rostov and Astrakhan regions by the bacteria Helicobacter pylori, to determine the frequency of H. pylori pathogenicity factors in different age groups of the population.Materials and methods:118 adults and 112 children were examined. Te presence of H. pylori DNA and the pathogenicity factors of CagA and VacA in the biopsy material of the mucous membrane of the antrum of the stomach was determined by PCR.Results:a signifcantly smaller percentage of H. pylori–positive patients is characteristic of the child population. Te prevalent H. pylori genotype in the infant population is the avirulent genotype Vac s2m2 (60%) (χ2: p <0.005). Genotype CagA + VacAs1 VacAm1 is a marker of peptic ulcer for adult population of the Rostov region.Conclusion:Te conducted studies allowed to establish differences in infection of the population with H. pylori bacteria and the frequency of the distribution of virulent genotypes depending on the region, age and severity of the pathology.

scholarly journals Urban-Rural Differences in Nutritional Status and Dietary Intakes of School-Aged Children in Cambodia

Nutrients ◽  
2018 ◽  
Vol 11 (1) ◽  
pp. 14 ◽  
Author(s):  
Yoko Horiuchi ◽  
Kaoru Kusama ◽  
Sar Kanha ◽  
Nobuo Yoshiike ◽  
Keyword(s):  
Nutritional Status ◽  
Rural Areas ◽  
Urban Areas ◽  
Age Groups ◽  
Overweight And Obesity ◽  
Dietary Intakes ◽  
Nutrition Survey ◽  
Rural And Urban Areas ◽  
School Aged Children ◽  
Urban Rural

: This study aimed to describe the nutritional status and dietary patterns of Cambodian school-aged children compared with those in the South East Asian Nutrition Survey (SEANUTS; Indonesia, Malaysia, Thailand, and Vietnam in 2011) and to clarify the urban-rural differences using data from a nationally representative sample. The survey was conducted in 2014/2015 with a sample of 2020 children aged 6–17 years from 136 randomly selected schools. Standardized anthropometric measurements and a 1-day dietary survey by 24-hour recall method were conducted. Extended analyses in the present study revealed that the difference between rural and urban areas was similar to that of the SEANUTS; the overall prevalence of stunting remained high (33.2%). Stunting was more prevalent in children living in rural areas than in those in urban areas (total: 36.4% vs 20.4%). In contrast, the overall prevalence of overweight and obesity was not as high (3.1%), but was higher among urban children in all age groups compared with those living in rural areas (total: 6.4% vs 2.3%). Overall, the dietary intake of children did not meet the local recommended dietary allowances, which was similar to the results of the SEANUTS and differed across urban and rural areas.

scholarly journals Helicobacter pylori associated with breastfeeding, nutritional status and recurrent abdominal pain in healthy Nigerian children

2014 ◽  
Vol 8 (04) ◽  
pp. 448-453 ◽  
Author(s):  
Idowu O Senbanjo ◽  
Kazeem A Oshikoya ◽  
Olisamedua F Njokanma
Keyword(s):  
Helicobacter Pylori ◽  
Abdominal Pain ◽  
Nutritional Status ◽  
Recurrent Abdominal Pain ◽  
University Teaching ◽  
Breastfeeding Duration ◽  
Pediatric Care ◽  
Enzyme Linked Immunosorbent Assay ◽  
Healthy Children ◽  
H Pylori

Introduction: There is limited knowledge about the associations of Helicobacter pylori (H. pylori) infections in developing countries. This study aimed to determine the current prevalence and associations of H. pylori infection with breastfeeding practices, nutritional status, and recurrent abdominal pain (RAP) in a group of apparently healthy children and adolescents in Lagos, Nigeria. Methodology: This was a prospective hospital-based study conducted at the Lagos State University Teaching Hospital that involved 118 children who came to the hospital for routine pediatric care. Seroprevalence status of the children was determined by measuring immunoglobulin G antibodies against H. pylori using enzyme-linked immunosorbent assay (ELISA). Results: Seventy-five (63.6%) children were seropositive for H. pylori. The prevalence of H. pylori infection increased significantly from 40.4% in children less than five years of age to 85.1% at six to ten years of age (χ2 = 20.9, p < 0.001). H. pylori infection was associated with low social class (OR = 3.24; 95% CI = 1.20-8.23, p = 0.016) and with RAP (OR = 3.47; 95% CI = 1.55-7.79, p = 0.002), but no association was observed with exclusive breastfeeding, duration of breastfeeding, and under-nutrition. Conclusions: The prevalence of H. pylori infection is high, particularly among children from low socioeconomic backgrounds in Lagos, Nigeria. It is associated with RAP. The effect of this infection on children’s health requires further studies.

scholarly journals Relation between Helicobacter pylori infection and gastrointestinal symptoms and syndromes

Gut ◽  
1997 ◽  
Vol 41 (2) ◽  
pp. 169-176 ◽  
Author(s):  
S Rosenstock ◽  
L Kay ◽  
C Rosenstock ◽  
L P Andersen ◽  
O Bonnevie ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Epigastric Pain ◽  
Gastrointestinal Symptoms ◽  
Igg Antibodies ◽  
Serum Samples ◽  
Ulcer Disease ◽  
Abdominal Symptoms ◽  
Nocturnal Pain ◽  
H Pylori ◽  
Upper Dyspepsia

Background—Helicobacter pylori is a human pathogen that colonises the gastric mucosa and causes permanent gastric inflammation.Aims—To assess the symptoms of H pylori infection in an adult unselected population.Subjects—A random sample of 3589 adult Danes who were examined in 1982 and 1987 (n=2987).Methods—Abdominal symptoms within the preceding year were recorded at both attendances. Circulating IgG antibodies against H pylori in serum samples drawn in 1982 were measured by using in-house indirect enzyme linked immunosorbent assays (ELISA).Results—People with increased levels of IgG antibodies to H pylori were more likely than uninfected individuals to report heartburn (odds ratio (OR) = 1.26, 95% confidence interval (CI) 1.03–1.54) and abdominal pain characterised by daily length (OR = 1.33, 95% CI 0.92–1.91), nocturnal occurrence (OR = 1.62, 95% CI 1.19–2.19), spring aggravation (OR = 1.68, 95% CI 0.70–4.05), and no relation to meals (OR = 0.62, 95% CI 0.43–0.91) or stress (OR = 0.69, 95% CI 0.50–0.95). The inclusion of people with increased levels of IgG antibodies to H pylori, but without upper dyspepsia, at study entry significantly increased the likelihood of reporting upper dyspepsia at follow up (OR = 1.71, 95% CI 1.24–2.36). People with epigastric pain and increased levels of IgM antibodies to H pylori only indicative of acute H pylori infection were more likely to report nocturnal pain, heartburn, nausea, and vomiting.Conclusions—H pylori infection may precede the development of dyspepsia and is associated with a variety of gastrointestinal symptoms in people with no history of peptic ulcer disease.

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