Associations of choline intake with hypertension and blood pressure among older adults in cross-sectional 2011 – 2014 NHANES differ by body mass index and comorbidity status

2021 ◽  
pp. 1-22
Author(s):  
Siraphat Taesuwan ◽  
Paradee Thammapichai ◽  
Ariel B. Ganz ◽  
Wachira Jirarattanarangsri ◽  
Julaluk Khemacheewakul ◽  
...  

Abstract Blood pressure (BP) is a known cardiovascular risk factor that is hypothesized to be inversely related to choline intake. A previous study suggested that this association may be more apparent in older adults and may differ according to demographic and health characteristics. The primary study objectives are to investigate the cross-sectional associations of total choline intake with BP (n=843) and prevalent hypertension (n=2,113) among U.S. adults aged ≥65 y using the sample from the 2011–2014 National Health and Nutrition Examination Survey. Logistic and multiple linear regression models for complex surveys were employed for hypertension status and BP respectively. Effect modification by sex, race, body mass index (BMI) and comorbidity status were separately investigated using an interaction term. Choline intake interacted with BMI (P-interaction=0.04) such that choline intake tended to be associated with lower odds of hypertension among people with BMI <18.5 kg/m2 (OR [95% CI]: 0.64 [0.4,1.00]; P=0.052). Choline intake was not associated with systolic BP (mean±SEM change per 100 mg of choline: −1.03±0.74 mmHg; P=0.16). In contrast, its relation to diastolic BP differed by cardiovascular comorbidity (P-interaction=0.03) with a non-significant (P=0.13) negative direction of association observed among those who were free of comorbidities and a non-significant (P=0.26) positive direction observed among those with comorbidities. Collectively, these results suggested that the associations of choline intake with BP levels and hypertension risk among older adults are dependent on other risk factors.

2020 ◽  
Vol 3 (2) ◽  
pp. 618-627
Author(s):  
Remita Ully Hutagalung

This research aims to seek the relation of the index of the body with blood pressure on the fire-extinguishing officers in Samarinda. The method for this research is using a cross-sectional research design. The results of this statistical test indicate a significant link between the body mass index and hypertension but with a weak correlation. The correlation direction shows a positive direction, and it can be concluded that the higher body mass index is, the greater the degree of hypertension experienced by individuals. This research finds that the calculation of body mass index can be a predictor of the occurrence of hypertension, especially in individuals with excess weight up to obesity. The community is efficiently screening the risk of hypertension and supervision through the calculation of mass body index. The public does not need to rely on the availability of blood pressure gauges in screening. Similar research in various types of communities further strengthened that the body mass index is strongly correlated with hypertension.   Keyword: Hypertension, Body Mass Index, Firefighter


2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 1096-1096
Author(s):  
Siraphat Taesuwan ◽  
Paradee Thammapichai ◽  
Ariel Ganz ◽  
Wachira Jirarattanarangsri ◽  
Julaluk Khemacheewakul ◽  
...  

Abstract Objectives The study objective is to investigate the relationships of choline intake with blood pressure (BP) and hypertension among U.S. adults aged ≥65 y using the sample from the 2011–2014 National Health and Examination Survey (NHANES). The association between choline-containing supplement usage and BP in adults aged ≥20 y was also assessed to confirm previous findings. Methods The cross-sectional associations of choline intake with prevalent hypertension (n = 2113) and BP (n = 843) were assessed among the NHANES older adults using logistic and multiple linear regression models for complex surveys, respectively. Logistic regression was used to test the association between supplemental choline use and prevalent hypertension in adults aged ≥20 y (n = 9561). Effect modification by sex, race/ethnicity, body mass index (BMI) and comorbidity were also investigated. Results Among older adults, choline intake interacted with BMI (P-interaction = 0.04) such that choline intake tended to be associated with lower odds of hypertension among people with BMI lower than 18.5 kg/m2 (odds ratio [95% Confidence Interval], OR [95% CI]: 0.64 [0.4,1.00]; P = 0.052). Choline intake was not associated with systolic BP. In contrast, its relation to diastolic BP differed by comorbidity (P-interaction = 0.03) with a negative direction of association observed among those who were free of comorbidities and a positive direction observed among those with comorbidities. No association was found between choline supplement use and the odds of hypertension. Conclusions Collectively, these results suggested that the associations of choline intake with BP levels and hypertension risk among older adults are mild and dependent on other risk factors. A higher choline intake may be beneficialy associated with BP among people who have healthier profiles. Funding Sources This study was supported by the Young Faculty Research Grant, Faculty of Agro-Industry, Chiang Mai, Thailand.


2019 ◽  
pp. 127-136
Author(s):  
Venti Agustina

Hipertensiadalah penyebab kematian utama di Indonesia. Kematian akibat hipertensi lebih banyak terjadi di perkotaan dibandingkan di desa. Tingginya kejadian hipertensi dipengaruhi oleh faktor yang dapat dikontrol (obesitas,berat badan lebih, konsumsi garam berlebih,aktivitas fisik rendah, perokok, dan konsumsi alkohol) dan faktor yang tidak dapat dikontrol (genetik, usia, dan jenis kelamin). Penelitian bertujuan memberikan gambarandistribusi tekanan darah dan indeks massa tubuh (IMT) pendudukperempuan di kota maupun di desa.Desain penelitian adalah deskriptif kuatitatif dengan pendekatan cross sectional. Data primer didapatkan melalui pengukuran tekanan darah, tinggi badan dan berat badan. Penelitian dilakukan di Desa Kutowinangun Kidul, Kecamatan Tingkir,Salatiga yang mewakili penduduk perempuan di perkotaan dan Desa Batur, Kecamatan Getasan, Kabupaten Semarangyang mewakili penduduk perempuan pedesaan. Adapun jumlah sampel masing-masing 66 respondendan 72responden. Hasil penelitian menunjukkan bahwa kejadian penyakit hipertensi, resiko obese dan obese lebih didominasi oleh respondendi perkotaan dibandingkan di pedesaan dengan rentang usia di atas 46 tahun. Respondendi desa dengan indeks massa tubuh normal cenderung mengalami pre-hipertensi (8,3%) dan hipertensi stadium I (6,9%) sementararesponden dengan resiko obese dan obese cenderung mengalami hipertensi stadium I (1,4%).Respondendi kota dengan indeks massa tubuh normal cenderung mengalami pre hipertensi (6,06%), hipertensi stadium I (4,5%) dan II (7,5%). Responden dengan resiko obese cenderung mengalami hipertensi stadium I (4,5%), dan responden dengan obese I dan II cenderung mengalami pre-hipertensi (4,5%).   Hypertension is the leading cause of death in Indonesia. Deaths due to hypertension are more common in urban areas than in villages. The high incidence of hypertension is influenced by factors that can be controlled (obesity, overweight, excessive salt consumption, low physical activity, smokers, and alcohol consumption) and factors that cannot be controlled (genetic, age, and sex). The study aimed to provide an overview of blood pressure distribution and body mass index (BMI) of female residents in cities and villages. The study design was descriptive quantitative with a cross sectional approach. Primary data was obtained through measurements of blood pressure, height and weight. The study was conducted in Kutowinangun Kidul Village, Tingkir Subdistrict, Salatiga representing women in urban areas and Batur Village, Getasan Subdistrict, Semarang Regency, representing rural women. The number of samples was 66 respondents and 72 respondents respectively. The results showed that the incidence of hypertension, the risk of obese and obese was more dominated by respondents in urban areas than in rural areas with ages above 46 years. Respondents in villages with normal body mass index tended to experience pre-hypertension (8.3%) and stage I hypertension (6.9%) while respondents with obese and obese risk tended to experience stage I hypertension (1.4%). Respondents in cities with normal body mass index tended to experience pre-hypertension (6.06%), stage I hypertension (4.5%) and II (7.5%). Respondents with obese risk tended to experience stage I hypertension (4.5%), and respondents with obese I and II tended to experience pre-hypertension (4.5%).


2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
I. O. Ernest-Nwoke ◽  
M. O. Ozor ◽  
U. Akpamu ◽  
M. O. Oyakhire

Aim. To study the relationship between body mass index (BMI) and blood pressure (BP) on visual acuity among apparently healthy residents of Ekpoma, Esan West Local Government Area of Edo State, Nigeria. Methodology. This is a cross-sectional descriptive study among 225 subjects (ages of 18–35 years) from whom BP, body weight, and height were collected. Visual acuity was measured using the Snellen chart following standard procedures of number of letters seen at 6-metre distance. The data were then analyzed using SPSS version 17. Results. The sampled population consists of 112 male and 113 female (mean age 31.72±14.2 years). Majority (180) of the respondents had normal visual acuity. However, compared with the respondents with normal BMI (R19.61±1.5; L19.67±1.70), visual acuity of underweight (R18.53±2.30; L18.53±2.70) and obese (R15.68±4.79; L17.73±1.70) were more deviated. Similarly, compared with respondent with normal BP (120–125/80–85 mmHg; R18.00±2.53; L18.07±3.11), hypotensive (R15.5±7.35; L15.00±10.20), and hypertensive (R15.01±21.25; L15.00±11.91) respondents had deviated visual acuity. Conclusion. Abnormal body weight (underweight and obese) and BP (hypotension and hypertension) have potential negative impacts on visual acuity. Based on the observed relationship between weights, BP, and visual acuity, eye examinations can be included as regular screening exercise for abnormal BMI and BP conditions.


2019 ◽  
Author(s):  
Zelalem Kofole ◽  
Diresbachew Haile ◽  
Yerukneh Solomon ◽  
Eyayu Girma

Abstract Background: The use of contraceptives has become prevalent among women in Ethiopia. Oral contraceptive use has been suggested to trigger changes in glucose metabolism, energy expenditure, blood pressure, and body weight, among the various populations and ethnic groups. Objective: To elucidate the pattern of fasting blood sugar (FBS), blood pressure and body mass index (BMI) among combined oral contraceptive (COC) pills users, taking into account other confounding factors including socioeconomic conditions and physical activity status. Methods: An institution based cross-sectional study design was employed. A total of 110 healthy women using pills were recruited as cases. Another 110 healthy women not using any hormonal contraceptives were recruited as matched controls. A study was conducted between October 2018 and January 2019. Fasting Capillary blood sample was collected from the study participants for the estimation of the FBS level. Systolic and diastolic blood pressures were measured and means arterial blood pressure was calculated for each participant. Body weight and height were measured to compute body mass index. Data obtained was entered and analyzed using IBM SPSS version 23 software packages. Results: FBS level in users was significantly increased compared to controls (88.55 ± 7.89 vs. 86.00 ± 9.85 in users and controls respectively, P = 0.025). There was a significant difference in mean arterial blood pressure of users compared to controls (88.2 ± 8.48 vs. 86.0 ± 6.74 respectively, P=0.04). The mean weight and body mass index of users were significantly increased (P = 0.03 and P = 0.003, respectively). Changes in mean fasting blood sugar level and mean weight of users were independent (P = 0.27 and P = 0.46) to the duration of use (3-12, 13-24 and ≥ 25 months). On the other hand, changes in mean body mass index and mean arterial blood pressure of users were dependent of the duration of use (P = 0.03 and P = 0.000 respectively). Conclusions: Overall, oral contraceptive pills use appears to cause a 2.9% increase in fasting blood glucose level, a 2.5% increase in mean arterial blood pressure and a 3.9% increase in body mass index among the users.


2021 ◽  
Vol 21 (2) ◽  
pp. 379-388
Author(s):  
Marcela Martins Soares ◽  
Leidjaira Lopes Juvanhol ◽  
Andreia Queiroz Ribeiro ◽  
Patrícia Feliciano Pereira ◽  
Sylvia C. C. Franceschini ◽  
...  

Abstract Objectives: to investigate the relation between maternal overweight and child’s anthropometric indices, identifying the interaction with the child's age. Methods: a cross-sectional study with mothers and their children under 2 years old. The mothers’ body mass index (BMI), waist-to-hip ratio and waist-to-height ratio was calculated. In children, we calculated height/age (H/A), body mass index/age (BMI/A), weight/height (W/H) and weight/age (W/A) indices. The means of the anthropometric indices of children with excess weight and maternal cardiometabolic risk were compared. Mothers and children’s anthropometric indices were correlated. Linear regression models were proposed. We investigated the child's age interaction with anthropometric variables of the dyad. Results: the means of BMI/A and W/H were higher in children of overweight mothers and the means of BMI/A, W/H and W/A were higher when mothers had increased risk for cardiometabolic diseases. There was an association of maternal weight and height with the W/A index; maternal BMI with W/H; maternal height with H/A; maternal weight, BMI and waist circumference with BMI/A. The children's age did not interact with the assessed parameters. Conclusion: children under 2 years of age, whose mothers are overweight, tend to show changes in weight, regardless of age.


2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
Tanica Lyngdoh ◽  
Bharathi Viswanathan ◽  
Edwin van Wijngaarden ◽  
Gary J. Myers ◽  
Pascal Bovet

We assessed the association between several cardiometabolic risk factors (CRFs) (blood pressure, LDL-cholesterol, HDL-cholesterol, triglycerides, uric acid, and glucose) in 390 young adults aged 19-20 years in Seychelles (Indian Ocean, Africa) and body mass index (BMI) measured either at the same time (cross-sectional analysis) or at the age of 12–15 years (longitudinal analysis). BMI tracked markedly between age of 12–15 and age of 19-20. BMI was strongly associated with all considered CRFs in both cross-sectional and longitudinal analyses, with some exceptions. Comparing overweight participants with those having a BMI below the age-specific median, the odds ratios for high blood pressure were 5.4/4.7 (male/female) cross-sectionally and 2.5/3.9 longitudinally (P<0.05). Significant associations were also found for most other CRFs, with some exceptions. In linear regression analysis including both BMI at age of 12–15 and BMI at age of 19-20, only BMI at age of 19-20 remained significantly associated with most CRFs. We conclude that CRFs are predicted strongly by either current or past BMI levels in adolescents and young adults in this population. The observation that only current BMI remained associated with CRFs when including past and current levels together suggests that weight control at a later age may be effective in reducing CRFs in overweight children irrespective of past weight status.


2021 ◽  
Author(s):  
Rebeca Mozun ◽  
Cristina Ardura-Garcia ◽  
Eva S. L. Pedersen ◽  
Jakob Usemann ◽  
Florian Singer ◽  
...  

AbstractBackgroundReferences from the Global Lung Function Initiative (GLI) are widely used to interpret children’s spirometry results. We assessed fit for healthy schoolchildren.MethodsLuftiBus in the school (LUIS) is a population-based cross-sectional study done from 2013-2016 in the canton of Zurich, Switzerland. Parents and children aged 6-17 years answered questionnaires about respiratory symptoms and lifestyle. Children underwent spirometry in a mobile lung function lab. We calculated GLI-based z-scores for FEV1, FVC, FEV1/FVC, and FEF25-75 for healthy White participants. We defined appropriate fit to GLI references by mean values ±0.5 z-scores. We assessed if fit varied by age, body mass index, height, and sex using linear regression models.ResultsWe analysed data from 2036 children with valid FEV1 measurements of which 1762 also had valid FVC measurements. The median age was 12.2 years. Fit was appropriate for children aged 6-11 years for all indices. In adolescents aged 12-17 years, fit was appropriate for FEV1/FVC (mean: -0.09; SD: 1.02) z-scores, but not for FEV1 (mean: -0.62; SD: 0.98), FVC (mean: -0.60; SD: 0.98), and FEF25-75 (mean: -0.54; SD: 1.02). FEV1, FVC, and FEF25-75 z-scores fitted better in children considered overweight (means: -0.25, -0.13, -0.38) than normal weight (means: -0.55, -0.50, -0.55; p-trend: <0.001, 0.014, <0.001). FEV1, FVC, and FEF25-75 z-scores depended on both age and height (p interaction: 0.034, 0.019, <0.01).ConclusionGLI-based FEV1, FVC, and FEF25-75 z-scores do not fit White Swiss adolescents well. This should be considered when using reference equations for clinical decision making, research and international comparison.Take home messageOur study suggests GLI-based FEV1, FVC, and FEF25-75 z-scores over detect abnormal lung function in Swiss adolescents, and more so among slimmer adolescents, which has important implications for clinical care, research, and international comparisons.


2016 ◽  
Vol 134 (4) ◽  
pp. 330-334 ◽  
Author(s):  
Felipe Pucci ◽  
Guilherme Machado ◽  
Edcarlo Solera ◽  
Fernanda Cenovicz ◽  
Christian Arruda ◽  
...  

ABSTRACT CONTEXT AND OBJECTIVE: Increased life expectancy among people with Down syndrome (DS) has introduced new environmental factors that may affect blood pressure (BP) and/or lead to obesity in this population. The aim here was to investigate BP levels and body mass index (BMI) in adults with DS, correlating these data with the patients' sex and age. DESIGN AND SETTING: Analytical cross-sectional observational study conducted in special schools in Curitiba (PR), Brazil. METHODS: 97 adult patients were included. BP was measured in accordance with the established guidelines. BMI was calculated by dividing the weight by the height squared (kg/m2). RESULTS: Sex had no influence on BMI; nor did systolic BP (SBP) or diastolic BP (DBP). The age range was from 18 to 56 years. No correlation was observed between increasing age and greater BMI or BP. Eighty-six individuals (88.7%) presented normal BP, eleven (11.3%) prehypertension and none hypertension. Twenty patients (20.4%) presented BP lower than 90 × 60 mmHg. BMI ranged from 18 to 48 kg/m2 (mean of 28.8 ± 3.92 kg/m2): 21.9% had normal weight; 40.7% were overweight; and 25.3% had obesity class I, 9.9% class II and 2.2% class III. Higher BMI was associated with significantly greater SBP and DBP (P = 0.0175 and P = 0.0015). CONCLUSION: Sex and age did not influence SBP, DBP or BMI in Brazilian adults with DS. Higher BMI was associated with greater BP (both systolic and diastolic).


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